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Original Articles

Role of ethanolic extract of Morus alba leaves on some biochemical and hematological alterations in irradiated male rats

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Pages 374-384 | Received 08 Jul 2017, Accepted 23 Jan 2018, Published online: 16 Feb 2018

References

  • Abd El-Kader MA, El-Kafrawy MH, Tolba AMA, Ali MM, Mohamed AS. 2015. Evaluation of taurine role on some biochemical and histological alterations in γ-irradiated rats. Int J Pharm Sci Rev Res. 30:263–271.
  • Ahmad MK, Khan AA, Mahmood R. 2013. Taurine ameliorates potassium bromate-induced kidney damage in rats. Amino Acids. 45:1109–1121.
  • Agrawal S, Kanwar K. 2007. Comparison of genetic transformation in Morus alba L. via different regeneration systems. Plant Cell Rep. 26:177–185.
  • Akleyev AV, Akushevich IV, Dimov GP, Veremeyeva GA, Varfolomeyeva TA, Ukraintseva SV, Yashin AI. 2010. Early hematopoiesis inhibition under chronic radiation exposure in humans. Radiat Environ Biophys. 49:281–291.
  • Al-Amri S, Alrasheedi A. 2016. Effect of fenugreek seeds on haematogenesis in irradiated rats. World Appl Sci J. 34:147–157.
  • Al-Awwadi NA, Araiz C, Bomet A, Delbosc S, Cristol JP, Linck N, Azay J, Teissedre PL, Cros G. 2005. Extracts enriched in different polyphenolic families normalize increased cardiac NADPH oxidase expression while having different effects on insulin resistance hypertension and cardiac hypertrophy in high fructose fed rats. J Agric Food Chem. 53:1.
  • Al-Janabi OSI, Amer MS, Khayri MH. 2015. Effects of the extracts of olive and morusalbaleaves on experimentally STZ induced diabetes in male rats. Inter J Sci Res. 4:1526–1532.
  • Allain CC, Poon LS, Chan CS, Richmond W, Fu PCC. 1974. Enzymatic determination of total serum cholesterol. Clin Chem. 20:470.
  • Alonzo F, Hertel- Aas T, Gilek M, Gilbin R, Oughton DH, Garnier-Laplace J. 2008. Modelling the propagation of effects of chromic exposure to ionizing radiation from individuals to populations. J. Environ Radioact. 99:1464–1473.
  • Andallu B, Varadcharyulu NCH. 2002. Control of hyperglycemia and retardation of cataract by mulberry (Morus indica L.) leaves in streptozotocin diabetic rats. Indian J Exp Biol. 40:791–795.
  • Andallu B, Varadacharyulu NC. 2007. Gluconeogenic substrates and hepatic gluconeogenic enzymes in streptozotocin diabetic rats: effect of mulberry (Morus indica L.) leaves. J Med Food. 10:41–48.
  • Asano N, Oseki K, Kizu H, Matsui K. 1994. Nitrogen-in-the-ring pyranoses and furanoses: structural basis of inhibition of mammalian glycosidases. J Med Chem. 37:3701–3706.
  • Asano N, Yamashita T, Yasuda K, Ikeda K, Kizu H, Kameda Y, Kato A, Nash RJ, Lee HS, Ryu KS. 2001. Polyhydroxylated alkaloids isolated from mulberry trees (Morus alba l) and silkworms (bombycmori l). J Agric Food Chem. 49:4208–4213.
  • Ashry OM, Hussein EM. 2007. Radio protective potency of ginseng on some haematopoeilic and physiological parameters in irradiated rats. Egypt J Rad Sci Appl. 20:46.
  • Azab KS, Bashandy M, Salem M, Ahmed O, Tawfik Z, Helal H. 2011. Royal jelly modulates oxidative stress and tissue injury in gamma irradiated male Wister albino rats. N Am J Med Sci. 3:268–276.
  • Banerjee SK, Maulik M, Mancahanda SC, Dinda AK, Gupta SK, Mulik SK. 2002. Dose dependent induction of endo- genous antioxidants in rat heart by chronic administration of garlic. Life Sci. 70:1509–1518.
  • Basu A, Basu S, Modak MJ. 1992. Structure-activity analyses of HIV-1 reverse transcriptase. Biochem Biophys Res Commun. 183:1131–1138.
  • Berry AJ, Katz JD. 2009. Occupational health. In: Barash PG, Cullen BF, Stoelting RK, Cahalan MK, Stock MC, editors. Clinical anesthesia. 6th ed. Philadelphia (PA): Lippincott Williams & Wilkins; p. 57–81.
  • Boerma M, Hauer-Jensen M. 2011. Preclinical research into basic mechanisms of radiation induced heart disease. Cardiol Res Pract. 2011:858262.
  • Bok S, Lee S, Park Y, Bae K, Son K, Jeong T, Choi M. 1999. Plasma and hepatic cholesterol and hepatic activities of 3-hydroxy-3-methyl-glutaryl-CoA reductase and acyl CoA: cholesterol transferase are lower in rats fed citrus peel extract or a mixture of citrus bioflavonoids. J Nutr. 129:1182–1185.
  • Butt MS, Nazir A, Tauseef MS, Schroen K. 2008. Morus alba L. mature’s functional tonic. Trends Fd Sci Technol. 19:505–512.
  • Chayalo PP, Lyakhovchun NN, Chobotko GM. 1992. Effect of single and fractionated γ-irradiation on rat blood lipids and tissues. UKr Biokhim ZH. 64:60–66.
  • Chen FJ, Nakashima N, Kimura I, Kimura M. 1995. Hypoglycemic activity and mechanism of extract from mulberry leaves (folium mori) and cortex mori radicis in streptozotocin induced diabetic mice. Yakugaku Zasshi. 115:476–482.
  • Chen J, Li X. 2007. Hypolipidemic effect of flavonoids from mulberry leaves in triton WR-1339 induced hyperlipidemic mice. Asia Pac J Clin Nutr. 16(Suppl 1):290–294.
  • Chew B, Park J. 2004. Carotenoid action on the immune response. J Nutr. 134: 257S–261S.
  • Dacie JV, Lewis MS. 1993. Practical haematology. 6th ed. London: Churchill Livingston; p. 37.
  • de Freitas RB, Boligon AA, Rovani BT, Piana M, de Brum TF, Jesus RS, Rother FC, Alves NM, da Rocha JBT, Athayde ML, et al. 2013. Effect of bklack grape juice against heart damage from acute gamma tbi in rats. Molexcules 18:12154–12167.
  • Derval V, Sichevskaia L. 2000. Exposure to ionizing radiation decreases haemoglobin binding to erythrocytes membrane. Biofizika 45:1086.
  • Devi GS, Prasad MH, Saraswathi I. 2002. Free radicals antioxidant enzymes and lipid peroxidation in different types of leukemias. Clin Chem Acta 293:53–62.
  • Dkhil MA, Bauomy AA, Diab MS, Al-Quraishy S. 2015. The antioxidant effect of Morus alba leaves extract on kidney, testes, spleen and intestine of mice. Pakistan J Zool. 47:393–397.
  • Duncan DB. 1955. Multiple range and multiple F-test. Biometrics 11:1.
  • Eaton S, Zaitoun AM, Record CO, Bartlett K. 1996. beta-Oxidation in human alcoholic and non-alcoholic hepatic steatosis. Clin Sci. 90:307–313.
  • Ebrahimzadeh MA, Ehsanifar S, Eslami B. 2009. Sambucusebuluse lburensis fruits: a good source for antioxidants. Pharmacogn Mag. 4:213–218.
  • Egea I, Sanchez BP, Romojaro F, Pretel MT. 2010. Six edible wild fruits as potential antioxidant additives or nutritional supplements. Plant Foods Hum Nutr. 65:121–129.
  • El-Batal AI, Azab KHSH, Saad HN, Rezk RG, El-Tahawy NA. 2008. Ameliorating effects of yeast glucan with zinc bisglycinate on histological and biochemical changes in γ-irradiated rats. Int J Agric Biol. 10:361–368.
  • El-Ganzuri M, El-Gawish M, Hanafi N, Taha W. 2015. The possible protective effect of bone marrow transplantation on the haematopoietic and lymphoid tissues in gamma irradiated rats. J Nucl Tech Appl Sci. 3:131–144.
  • El-Mahdy AA, Ghoneim MAM. 2013. Evaluation of tryptophan role on some biochemical and histological alterations in irradiated rats. Biosci Res. 10:12–19.
  • El-Sayed SM. 2010. Lupine alleviate hyperglycemia in streptozotcin diabetic γ- irradiated rats. J Rad Res Appl Sci. 3:293–309.
  • Eshak MG, Osman HF. 2013. Role of moringaoleifera leaves on biochemical and genetical alterations in irradiated male rats. Middle East J Sci Res. 16:1303–1315.
  • Ezz MK. 2011. The ameliorative effect of Echinacea purpurea against gamma radiation induced oxidative stress and immune responses in male rats. Aust J Basic Appl Sci. 5:506–512.
  • Fossati P, Principe L. 1982. Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide. Clin Chem. 28:2077.
  • Gad MZ, El-Sawalhi MM, Ismail MF, El-Tanbouly ND. 2006. Biochemical study of the anti-diabetic action of the Egyptian plants fenugreek and balanites. Mol Cell Biochem. 281:173.
  • Gomez-Millan J. 2009. Radiation therapy in the elderly: more side effects and complications? Crit Rev Oncol Hematol. 71:70–78.
  • Hall EJ. 2000. Radiobiology for the radiologist. 5th ed. Lippincott Williams and Wilkins; p. 588.
  • Hamzaa RG, El-Shahat AN, Mekawey HMS. 2012. The antioxidant role of mulberry (Morus alba L.) fruits in ameliorating the oxidative stress induced in γ-irradiated male rats. Biochem Anal Biochem. 1:122.
  • Henke M, Guttenberger R, Barke A, Pajonk F, Potter R, Frommhold H. 1999. Erythropoietin for patients undergoing radiotherapy: a pilot study. Radiother Oncol. 50:185.
  • Hussien EM, Darwish MM, Ali SE. 2007. Prophylactic role of combined treatment with co enzyme Q 10 and vitamin E against radiation in male rats. Egypt J Rad Sci Appl. 20:181–194.
  • Japon-Lujan R, Luque de Castro MD. 2006. Super heated liquid extraction of oleuropein and related biophenols from olive leaves. J Chromatogr A. 1136:185–191.
  • Kafafy YA, Ashry OM. 2001. Antioxidative potential of parsley on gamma irradiated rats. Egypt J Rad Sci Appl. 14:125–142.
  • Kimura T, Nakagawa K, Kubota H, Kojima Y, Yamagishi K, Oita S, Oikawa S, Miyazawa T. 2007. Food-grade mulberry powder enriched with 1-deoxynojirimycin suppresses the elevation of postprandial blood glucose in humans. J Agric Food Chem. 55:5869–5874.
  • Koc M, Buyukokuroglu ME, Taysi S. 2002. The effect of melatonin on peripheral blood cells during total body irradiation in rats. Biol Pharm Bull. 25:656.
  • Kornberg A, Horecker BL. 1955. Gucose- 6- phosphate dehydrogenase. In: Colowick SP, Kaplan NO, editors. Methods in enzymology. Vol. 1, New York and London: Academic Press, Inc.; p. 323–327.
  • Lang CH, Dobrescu C. 1989. Interleukin-1 induced increases in glucose utilization are insulin mediated. Life Sci. 45:27–34.
  • Lee MS, Kim YH, Park WS, Ahn WG, Park OK, Kwon SH, Mortta K, Shin I, Iter S. 2013. Antidepressant like effects of cortex moriradicis extract via bidirectional phyosphorylation of glucocorticoid receptors in the hippocampus. Behav Brain Res. 236:56–61.
  • Mansour HH, Tawfik SS. 2011. Early treatment of radiation induced heart damage in rats by caffeic acid phenethyl ester. Eur J Pharmacol. 692:46–51.
  • Mazimba O, Majinda RR, Mothanka D. 2011. Antioxidant and antibacterial constituents from Morus niggra. Afr J Pharm Pharmacol. 5:751–754.
  • Miura N, Satoh M, Imura N, Naganuma A. 1998. Protective effect of bismuth mitrate against injury to the bone marrow by gamma irradiation in mice: possible involvement of induction of metallothionein synthesis. J Pharmacol Exp Therapeut. 286:1427–1430.
  • Mohit J, Daniel A, Lei C, Chee C, Bo W, David R, Stanley K, Douglas B, Jane A, Diane E, et al. 2003. Glucose-6-phosphate dehydrogenase modulates cytosolic redox status and contractile phenotype in adult cardiomyocytes. Circulat Res. 93:9.
  • Mukherjee S, Ghhosh S, Choudhury S, Adhikary A, Manna K, Dey S, Sa G, Das T, Chattopadhyay S. 2013. Pomegranate reverses methotrexate-induced oxidative stress and apoptosis in hepatocytes by modulating Nrf2-NF-κB pathways. J Nutr Biochem. 24:2040–2050.
  • Murray RK, Granner DK, Mayes PA, Rodwell VW. 2003. Harper´s illustrated biochemistry. 26th ed. Printed in the United States of America: The McGraw-Hill Companies.
  • Nazari M, Hajizadeh MR, Eftekhar A, Fattahpour S, Ziaaddini H, Hassanshahi G, Mahmoodi M, Rezaeian M. 2014. Comparative regulatory effects of moru salba leaf extracts on hepatic enzymes in streptozotocin induced diabetic and non diabetic rats. Med Chem. S1:003.
  • Nie Y, He JL, Hsia SL. 1993. A micro enzymatic method for determination of choline containing phospholipids in serum and high density lipoproteins. Lipids 28:949.
  • Nunia V, Goyal PK. 2004. Prevention of gamma radiation induced anaemia in mice by diltiazem. J Radiat Res. 45:11–17.
  • Oh H, Ko EK, Jun JY, Oh MH, Park SU, Kang KH, Lee HS, Kim YC. 2002. Hepatoprotective and free radical scavenging activities of prenylflavonoids, coumarin, and stilbene from Morus alba. Planta Med. 68:932–934.
  • Omaima M, Maha G, Neveen H, Manar A. 2013. Immunostimulatory Role of panax ginseng in irradiated bone marrow transplanted rats. Int J Acad Res. 5:115–123.
  • Pawlowska AM, Oleszek W, Braca A. 2008. Quali-quantitative analyses of Flavonoids of Morus nigra L. and Morus alba L. (Moraceae) fruits. J Agric Food Chem. 56:3377–3380.
  • Pispirigos K, Chrysanthopoulos K. 2001. Evaluation of cardiac subacute toxicity of ciprofloxacin in rats using serum biochemical parameters. Drug Res. 51:582–587.
  • Prasad NR, Mahesh T, Menon VP, Jeevanram PK, Pugalendi KV. 2005. Radioprotective effect of sesamol on radiation induced DNA damage, lipid peroxidation and antioxidant levels in cultured human lymphocytes. Toxicology 209:225–235.
  • Radojkovic MM, Zekovic ZP, Vidovic SS, Kočar DD, Maškovič PZ. 2012. Free radical scavenging activity and total phenolic and flavonoid comments of mulberry (morus spp. L. moraceae) extracts. Hem Ind. 66:547–552.
  • Rajapakse N, Kim MM, Mendis E, Kim SK. 2007. Inhibition of free radical-mediated oxidation of cellular biomolecules by carboxylated chitooligosaccharides. Bioorg Med Chem. 15:997–1003.
  • Ramadan FL. 2007. Evaluation of the synergistic effect of danazol and radiation exposure on some biochemical functions in female albino rats. Egypt J Hospit Med. 27:255–262.
  • Rostamian V, Shakeri F, Estakhr J. 2011. The effect of hydro-alcoholic extract of strawberry leaf on sugar and lipids in serum of diabetic rats. Pharmacologyonline. 3:1171–1175.
  • Said UZ, Azab KS. 2006. Efficacy of wheat germ oil in modulating radiation induced heart damage in rats. Egypt J Rad Sci Apllic. 19: 433–452.
  • Salman MMMA, Mohi Eldin MM, Kasem NRA. 2015. Physiological effects of bee venom and propolis on irradiated albino rats. Danisb J Agric Anim Sci. 1:11–21.
  • Sato Y, Sato K, Suzuki Y. 1999. Mechanism of free radical-induced hemolysis of human erythrocytes: comparison of calculated rate constants for hemolysis with experimental rate constants. Arch Biochem Biophys. 366:61
  • Sedláková A, Borikova K, Ahlers I. 1986. Changes in lipoprotein lipase activity in the adipose tissue and heart of non-lethally X-irradiated rats. Physiol Bohemoslov. 35:400–405.
  • Singh P, Jain A, Kaur P. 2004. Impact of hypoglycemia and diabetes on CNS: correlation of mitochondrial ox. St with DNA damage. Mol Cell Biochem. 260:153.
  • Sleim N, Desouky O, Ali S, Ibrahiem H, Ashry H. 2009. Effect of gamma irradiation on some biophysical properties of red blood cell membrane. Romania J Biophys. 19:171–185.
  • Soliman MG, Ashry MO, Ahmed MAE, Abd El-Naby YH. 2015. Improvement of hematopoietic and immunologic findings in sublethal gamma irradiated rats treated with bone marrow transplantation and wheat germ oil. JIBTVA. 4:9–18.
  • Spitz DR, Azzam EI, Li JJ, Gius D. 2004. Metabolic oxidation/reduction reactions and cellular responses to ionizing radiation: a unifying concept in stress response biology. Cancer Metastasis Rev. 23:311.
  • Srivastava N, Kaushik N, Gupta P. 2002. Zinc induced changes in the liver and muscle of fish, channa punctatus (Bloch). J Ecophysiol Occup Health. 2:197.
  • Tietz NW. 1986. Textbook of clinical chemistry. Philadelphia: WB Saunders Co.; p. 796.
  • Tietz NW. 2005. Textbook of clinical chemistry and molecular diagnostics. 4th ed. Philadelphia: WB Saunders Co.
  • Trosic I. 2001. Multinucleated giant cell appearance after whole body microwave irradiation of rats. Int J Hyg Environ Health. 204:126–133.
  • WHO. 2012. World Health Organization Ionizing radiation, health effects and protective measures (fact sheet number 371).
  • Wild S, Roglic G, Green A, Sicree R, King H. 2004. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care. 27:1047–1053.
  • Witztum J. 2002. Splenic immunity and atherosclerosis: a glimpse into a novel paradigm. J Clin Invest. 109:721–724.
  • Wu G, Fang YZ, Yang S, Lupton JR, Turner ND. 2004. Glutathione metabolism and its implications for health. J Nutr. 134:489–492.
  • Young DS. 2001. Effects of disease on clinical lab tests. 4th ed. Washington (DC): AACC Press.
  • Zafar MS, Muhammad F, Javed I, Aktar M, Khaliq T, Aslam B, Waheed A, Yasmin R, Zafar H. 2013. White mulberry (Morus alba) a brief phytochemical and pharmacological evaluations account. Int J Agric Biol. 15:612–620.
  • Zahkouk SA, El-Kabany HA, Dawoud MH. 2017. Therapeutic effects of an ethanolic olive leaves extract or bone marrow mesenchymal stem cells against liver injury induced by gamma radiation. Egypt J Hosp Med. 67:382–391.
  • Zarybnicka L, Vavrova J, Havelek R, Tichy A, Pejchal J, Sinkorova Z. 2013. Lymphocyte subsets and their H2AX phosphorylation in response to in vivo irradiation in rats. Int J Radiat Biol. 89:110–117.
  • Zhao H, Wang Z, Ma F, Yang X, Cheng C, Yao L. 2012. Protective effect of anthocyanin from lonicera caerulea var. edulis on radiation-induced damage in mice. Int J Mol Sci. 13:11773–11782.
  • Zollner N, Kirsch K. 1962. Colorimetric method for determination of total lipids. Z Ges Exp Med. 135:545–550.

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