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Original Articles

Gamma irradiation of aloe-emodin induced structural modification and apoptosis through a ROS- and caspase-dependent mitochondrial pathway in stomach tumor cells

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Pages 403-416 | Received 12 May 2017, Accepted 29 Jan 2018, Published online: 06 Mar 2018

References

  • Altmann KH, Gertsch J. 2007. Anticancer drugs from nature-natural products as a unique source of new microtubule-stabilizing agents. Nat Prod Rep. 24:327–357.
  • Byun EB, Sung NY, Kim JH, Choi J, Matsui T, Byun MW, Lee JW. 2010. Enhancement of anti-tumor activity of gamma-irradiated silk fibroin via immunomodulatory effects. Chem Biol Interact. 186:90–95.
  • Byun EB, Sung NY, Kwon SK, Song BS, Kim JH, Choi J, Matsui T, Byun M-W, Lee J-W. 2009. In vitro and in vivo studies on the cytotoxicity of irradiated silk fibroin against mouse melanoma tumor cell. Radiat Phys Chem. 78:429–431.
  • Byun EB, Sung NY, Park JN, Yang MS, Park SH, Byun EH. 2015. Gamma-irradiated resveratrol negatively regulates LPS-induced MAPK and NF-κB signaling through TLR4 in macrophages. Int Immunopharmacol. 25:249–259.
  • Byun EB, Sung NY, Yang MS, Lee BS, Song DS, Park JN, Kim JH, Jang BS, Choi DS, Park SH, et al. 2014. Anti-inflammatory effect of gamma-irradiated genistein through inhibition of NF-κB and MAPK signaling pathway in lipopolysaccharide-induced macrophages. Food Chem Toxicol. 74:255–264.
  • Byun EH, Kim JH, Sung NY, Choi J, Lim ST, Kim KH, Jang B-S, Choi D-S, Park S-H, Yu Y-B, Byun E-H. 2008. Effects of gamma irradiation on the physical and structural properties of b-glucan. Radiat Phys Chem. 77:781–786.
  • Choi J, Kim HJ. 2013. Preparation of low molecular weight fucoidan by gamma-irradiation and its anticancer activity. Carbohydr Polym. 97:358–362.
  • Choi SR, Lee JH, Kim JY, Park KW, Jeong IY, Shim KH, Lee MK, Seo KI. 2011. Decursin from Angelica gigas Nakai induces apoptosis in RC-58T/h/SA#4 primary human prostate cancer cells via a mitochondria-related caspase pathway. Food Chem Toxicol. 49:2517–2523.
  • Dejeana LM, Martinez-Caballero S, Manon S, Kinnally KW. 2006. Regulation of the mitochondrial apoptosis-induced channel, MAC, by BCL-2 family proteins. Biochim Biophys Acta. 1762:191–201.
  • Eshun K, He Q. 2004. Aloe vera: a valuable ingredient for the food, pharmaceutical and cosmetic industries – a review. Crit Rev Food Sci Nutr. 44:91–96.
  • Gackowski D, Banaszkiewicz Z, Rozalski R, Jawien A, Olinski R. 2002. Persistent oxidative stress in colorectal carcinoma patients. Int J Cancer. 101:395–397.
  • Gordaliza M. 2007. Natural products as leads to anticancer drugs. Clin Transl Oncol. 9:767–776.
  • Green DR. 2011. Means to an end: apoptosis and other cell death mechanisms. New York: Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
  • Hajra KM, Liu JR. 2004. Apoptosome dysfunction in human cancer. Apoptosis. 9:691–704.
  • Henderson B, Poole S, Wilson M. 1996. Bacterial modulins: a novel class of virulence factors which cause host tissue pathology by inducing cytokine synthesis. Microbiol Rev. 60:316–341.
  • Hersh D, Weiss J, Zychlinsky A. 1998. How bacteria initiate inflammation: aspects of the emerging story. Curr Opin Microbiol. 1:43–48.
  • Hu W, Kavanag JJ. 2003. Anticancer therapy targeting the apoptotic pathway. Lancet Oncol. 4:721–729.
  • Ilyina AW, Tikhonov VE, Albulov AL, Varlamov VP. 2000. Enzymic preparation of acid-free-water-soluble chitosan. Process Biochem. 35:563–568.
  • Jeon YI, Kim SK. 2002. Production of chito-oligosaccharides using an ultrafiltration membrane reactor and their antibacterial activity. Carbohydr Res. 41:133–141.
  • Jung HJ, Park HR, Jung UJ, Jo SK. 2009. Radiolysis study of genistein in methanolic solution. Radiat Phys Chem. 78:386–393.
  • Kim R, Emi M, Tanabe K. 2006. Role of mitochondria as the gardens of cell death. Cancer Chemother Pharmacol. 57:545–553.
  • Kozlowski D, Marsal P, Steel M, Mokrini R, Duroux JL, Lazzaroni R, Trouillas P. 2007. Theoretical investigation of the formation of a new series of antioxidant depsides from the radiolysis of flavonoid compounds. Radiat Res. 168:243–252.
  • Kroemer G, Galluzzi L, Brenner C. 2007. Mitochondrial membrane permeabilization in cell death. Physiol Rev. 87:99–163.
  • Kuo P, Lin TC, Lin CC. 2002. The antiproliferative activity of aloe-emodin is through p53-dependent and p21-dependent apoptotic pathway in human hepatoma cell lines. Life Sci. 71:1879–1892.
  • Lee EM, Bai HW, Lee SS, Hong SH, Cho SY, Chung BY. 2012. Gamma irradiation improves the antioxidant activity of Aloe vera (Aloe barbadensis miller) extracts. Radiat Phys Chem. 81:1029–1032.
  • Lee HZ, Hsu SL, Liu MC, Wu CH. 2001. Effects and mechanisms of aloe-emodin on cell death in human lung squamous cell carcinoma. Eur J Pharmacol. 431:287–295.
  • Lee SL, Lee MS, Song KB. 2005. Effect of gamma-irradiation on the physicochemical properties of gluten films. Food Chem. 92:621–625.
  • Li H, Zhu H, Xu CJ, Yuan J. 1998. Cleavage of Bid by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell. 94:491–501.
  • Marfak A, Trouillas P, Allais DP, Calliste CA, Cook-Moreau J, Durouxa JL. 2004. Reactivity of flavonoids with 1-hydroxyethyl radical: a gamma-radiolysis study. Biochim Biophys Acta. 1670:28–39.
  • Micke O, Seegenschmiedt MH. 2002. Consensus guidelines for radiation therapy of benign diseases: a multicenter approach in Germany. Int J Radiat Oncol Biol Phys. 52:496–513.
  • Ouyang L, Shi Z, Zhao S, Wang FT, Zhou TT, Liu B, Bao JK. 2012. Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis. Cell Prolif. 45:487–489.
  • Park JH, Hyun CK, Shin HK, Yeo IH. 1997. Effects of heat-treatment, sugar addition and fermentation on cytotoxicity of Korean mistletoe. Kor J Food Sci Technol. 29:362–368.
  • Pecere T, Gazzola MV, Mucignat C, Parolin C, Vecchia FD, Cavaggioni A, Basso G, Diaspro A, Salvato B, Carli M, et al. 2000. Aloe-emodin is a new type of anticancer agent with selective activity against neuroectodermal tumors. Cancer Res. 60:2800–2804.
  • Penninger JM, Kroemer G. 2003. Mitochondria, AIF and caspases-rivaling for cell death execution. Nat Cell Biol. 5:97–99.
  • Reynolds T. 1985. The compounds in Aloe leaf exudates: a review. Bot J Linn Soc. 90:157–177.
  • Seegenschmiedt MH, Katalinic A, Makoski H, Haase W, Gademann G, Hassenstein E. 2000. Radiation therapy for benign diseases: patterns of care study in Germany. Int J Radiat Oncol Biol Phys. 47:195–202.
  • Simon HU, Haj-Yehia A, Levi-Schaffer F. 2000. Role of reactive oxygen species (ROS) in apoptosis induction. Apoptosis. 5:415–418.
  • Stoclet JC, Chataigneau T, Ndiaye M, Oak MH, Bedoui J, Chataigneau M, Schini-Kerth VB. 2004. Vascular protection by dietary polyphenols. Eur J Pharmacol. 500:299–313.
  • Sung NY, Byun EB, Song DS, Jin YB, Kim JK, Park JH, Song BS, Jung PM, Byun MW, Lee JW, et al. 2013. Effect of gamma irradiation on mistletoe (Viscum album) lectin-mediated toxicity and immunomodulatory activity. FEBS Open Biol. 3:106–111.
  • Sung NY, Byun EB, Song DS, Yoo YC, Kim JK, Park JH, Song B-S, Park S-H, Lee J-W, Yu Y-B, Kim J-H. 2012. Low molecular weight β-Glucan stimulates doxorubicin-induced suppression of immune functions in mice. Food Sci Biotechnol. 21:645–651.
  • Susin SA, Daugas E, Ravagnan L. 2000. Two distinct pathways leading to nuclear apoptosis. J Exp Med. 192:571–579.
  • Veeriah S, Hofmann T, Glei M, Dietrich H, Will F, Schreier P, Knaup B, Pool-Zobel BL. 2007. Apple polyphenols and products formed in the gut differently inhibit survival of human cell Lines derived from colon adenoma (LT97) and carcinoma (HT29). J Agric Food Chem. 55:2892–2900.
  • Wan CK, Wang C, Cheung HY, Yang MS, Fong WF. 2005. Triptolide induces Bcl-2 cleavage and mitochondria dependent apoptosis in p53-dependent HL-60 cells. Cancer Lett. 241:1–11.
  • Wang C, Youle RJ. 2009. The role of mitochondria in apoptosis. Annu Rev Genet. 43:95.
  • Waxman DJ, Schwartz PS. 2003. Harnessing apoptosis for improved anticancer gene therapy. Cancer Res. 63:8563–8572.
  • Wong RSY. 2011. Apoptosis in cancer: from pathogenesis to treatment. J Exp Clin Cancer Res. 30:1–14.

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