Clinical characteristics, risk factors, and outcomes after adjuvant radiotherapy for patients with thymoma in the United States: analysis of the Surveillance, Epidemiology, and End Results (SEER) Registry (1988–2013)

References

• Ahmad U, Huang J. 2013. Current readings: the most influential and recent studies involving surgical management of thymoma. Semin Thorac Cardiovasc Surg. 25:144–149.
   PubMedGoogle Scholar
• Engels EA, Pfeiffer RM. 2003. Malignant thymoma in the United States: demographic patterns in incidence and associations with subsequent malignancies. Int J Cancer. 105:546–551.
   PubMed Web of Science ®Google Scholar
• Engels EA. 2010. Epidemiology of thymoma and associated malignancies. J Thorac Oncol. 5(10 Suppl.4):S260–S265.
   Web of Science ®Google Scholar
• Ettinger DS, Riely GJ, Akerley W, Borghaei H, Chang AC, Cheney RT, Chirieac LR, D'Amico TA, Demmy TL, Govindan R, et al. 2013. Thymomas and thymic carcinomas: Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 11:562–576.
   PubMed Web of Science ®Google Scholar
• Falkson CB, Bezjak A, Darling G, Gregg R, Malthaner R, Maziak DE, Yu E, Smith CA, McNair S, Ung YC, et al. 2009. The management of thymoma: a systematic review and practice guideline. J Thorac Oncol. 4:911–919.
   PubMed Web of Science ®Google Scholar
• Fernandes AT, Shinohara ET, Guo M, Mitra N, Wilson LD, Rengan R, Metz JM. 2010. The role of radiation therapy in malignant thymoma: a Surveillance, Epidemiology, and End Results database analysis. J Thorac Oncol. 5:1454–1460.
   PubMed Web of Science ®Google Scholar
• Filosso PL, Galassi C, Ruffini E, Margaritora S, Bertolaccini L, Casadio C, Anile M, Venuta F. 2013. Thymoma and the increased risk of developing extrathymic malignancies: a multicentre study. Eur J Cardiothorac Surg. 44:219–224; discussion 224.
   PubMed Web of Science ®Google Scholar
• Forquer JA, Rong N, Fakiris AJ, Loehrer PJ, Sr, Johnstone PA. 2010. Postoperative radiotherapy after surgical resection of thymoma: differing roles in localized and regional disease. Int J Radiat Oncol Biol Phys. 76:440–445.
   PubMed Web of Science ®Google Scholar
• Fritz A, WHO. 2000. International classification of diseases for oncology. 3rd ed. Geneva: World Health Organization.
   Google Scholar
• Girard N, Mornex F. 2011. The role of radiotherapy in the management of thymic tumors. Thorac Surg Clin. 21:99–105, vii.
   PubMed Web of Science ®Google Scholar
• Girard N, Ruffini E, Marx A, Faivre-Finn C, Peters S. 2015. Thymic epithelial tumours: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 26(Suppl.5):v40–v55.
   PubMed Web of Science ®Google Scholar
• Guerrera F, Rendina EA, Venuta F, Margaritora S, Ciccone AM, Novellis P, Novero D, Anile M, Bora G, Rena O, et al. 2015. Does the World Health Organization histological classification predict outcomes after thymomectomy? Results of a multicentre study on 750 patients. Eur J Cardiothorac Surg. 48:48–54.
   PubMed Web of Science ®Google Scholar
• Huang J, Ahmad U, Antonicelli A, Catlin AC, Fang W, Gomez D, Loehrer P, Lucchi M, Marom E, Nicholson A, et al. 2014. Development of the international thymic malignancy interest group international database: an unprecedented resource for the study of a rare group of tumors. J Thorac Oncol. 9:1573–1578.
   PubMed Web of Science ®Google Scholar
• Jackson MW, Palma DA, Camidge DR, Jones BL, Robin TP, Sher DJ, Koshy M, Kavanagh BD, Gaspar LE, Rusthoven CG. 2017. The impact of postoperative radiotherapy for thymoma and thymic carcinoma. J Thorac Oncol. 12:734–744.
   PubMed Web of Science ®Google Scholar
• Kersh CR, Eisert DR, Hazra TA. 1985. Malignant thymoma: role of radiation therapy in management. Radiology. 156:207–209.
   PubMed Web of Science ®Google Scholar
• Kim E, Thomas CR. Jr. 2015. Conditional survival of malignant thymoma using national population-based surveillance, epidemiology, and end results (SEER) registry (1973–2011). J Thorac Oncol. 10:701–707.
   PubMed Web of Science ®Google Scholar
• Koga K, Matsuno Y, Noguchi M, Mukai K, Asamura H, Goya T, Shimosato Y. 1994. A review of 79 thymomas: modification of staging system and reappraisal of conventional division into invasive and non-invasive thymoma. Pathol Int. 44:359–367.
   PubMed Web of Science ®Google Scholar
• Kondo K, Monden Y. 2003. Therapy for thymic epithelial tumors: a clinical study of 1,320 patients from Japan. Ann Thorac Surg. 76:878–884. discussion 884–875.
   PubMed Web of Science ®Google Scholar
• Lim YJ, Kim E, Kim HJ, Wu HG, Yan J, Liu Q, Patel S. 2016. Survival impact of adjuvant radiation therapy in Masaoka stage II to IV thymomas: a systematic review and meta-analysis. Int J Radiat Oncol Biol Phys. 94:1129–1136.
   PubMed Web of Science ®Google Scholar
• Lim YJ, Kim HJ, Wu HG. 2015. Role of postoperative radiotherapy in nonlocalized thymoma: propensity-matched analysis of surveillance, epidemiology, and end results database. J Thorac Oncol. 10:1357–1363.
   PubMed Web of Science ®Google Scholar
• Liu Q, Gu Z, Yang F, Fu J, Shen Y, Wei Y, Tan L, Zhang P, Han Y, Chen C, et al. 2016. The role of postoperative radiotherapy for stage I/II/III thymic tumor-results of the ChART retrospective database. J Thorac Dis. 8:687–695.
   PubMed Web of Science ®Google Scholar
• Ma J, Sun X, Huang L, Xiong Z, Yuan M, Zhang S, Han CB. 2016. Postoperative radiotherapy and tumor recurrence after complete resection of stage II/III thymic tumor: a meta-analysis of cohort studies. OncoTargets Ther. 9:4517–4526.
   PubMed Web of Science ®Google Scholar
• Masaoka A, Monden Y, Nakahara K, Tanioka T. 1981. Follow-up study of thymomas with special reference to their clinical stages. Cancer. 48:2485–2492.
   PubMed Web of Science ®Google Scholar
• Omasa M, Date H, Sozu T, Sato T, Nagai K, Yokoi K, Okamoto T, Ikeda N, Tanaka F, Maniwa Y. 2015. Postoperative radiotherapy is effective for thymic carcinoma but not for thymoma in stage II and III thymic epithelial tumors: the Japanese Association for Research on the Thymus Database Study. Cancer. 121:1008–1016.
   PubMed Web of Science ®Google Scholar
• Patel S, Macdonald OK, Nagda S, Bittner N, Suntharalingam M. 2012. Evaluation of the role of radiation therapy in the management of malignant thymoma. Int J Radiat Oncol Biol Phys. 82:1797–1801.
   PubMed Web of Science ®Google Scholar
• Penn CR, Hope-Stone HF. 1972. The role of radiotherapy in the management of malignant thymoma. Br J Surg. 59:533–539.
   PubMed Web of Science ®Google Scholar
• Rimner A, Yao X, Huang J, Antonicelli A, Ahmad U, Korst RJ, Detterbeck F, Gomez DR. 2016. Postoperative radiation therapy is associated with longer overall survival in completely resected stage II and III thymoma–an analysis of the international thymic malignancies interest group retrospective database. J Thorac Oncol. 11:1785–1792.
   PubMed Web of Science ®Google Scholar
• Scorsetti M, Leo F, Trama A, D'Angelillo R, Serpico D, Macerelli M, Zucali P, Gatta G, Garassino MC. 2016. Thymoma and thymic carcinomas. Crit Rev Oncol Hematol. 99:332–350.
   PubMed Web of Science ®Google Scholar
• SEaERSP. Research Data. 1973–2013. National Cancer Institute, DCCPS, Surveillance Research Program, Surveillance Systems Branch, released April 2016, based on the November 2015 submission. www.seer.cancer.gov
   Google Scholar
• Siesling S, van der Zwan JM, Izarzugaza I, Jaal J, Treasure T, Foschi R, Ricardi U, Groen H, Tavilla A, Ardanaz E. 2012. Rare thoracic cancers, including peritoneum mesothelioma. Eur J Cancer. 48:949–960.
   PubMed Web of Science ®Google Scholar
• Toothaker TBRM. 2009. Paraneoplastic neurological syndromes: a review. Neurologist. 15:21–33.
   PubMed Web of Science ®Google Scholar
• Travis WD, Brambilla E, Müller-Hermelink HK, Harris CC. 2004. In: Mueller-Hermelink H, editor. Tumours of the thymus. World Health Organization Classification of Tumours: pathology and genetics. Tumours of the lung, pleura, thymus, and heart. Lyon: IRC Press; p. 148–151.
   Google Scholar
• van Geffen WH, Sietsma J, Roelofs PM, Hiltermann TJ. 2011. A malignant retroperitoneal mass – a rare presentation of recurrent thymoma. BMJ Case Rep. 2011. DOI:10.1136/bcr.09.2011.4737
   PubMedGoogle Scholar
• Venuta F, Anile M, Diso D, Vitolo D, Rendina EA, De Giacomo T, Francioni F, Coloni GF. 2010. Thymoma and thymic carcinoma. Eur J Cardiothorac Surg. 37:13–25.
   PubMed Web of Science ®Google Scholar
• Wang F, Pang L, Fu J, Shen Y, Wei Y, Tan L, Zhang P, Han Y, Chen C, Zhang R, et al. 2016. Postoperative survival for patients with thymoma complicating myasthenia gravis-preliminary retrospective results of the ChART database. J Thorac Dis. 8:711–717.
   PubMed Web of Science ®Google Scholar
• Weis CA, Yao X, Deng Y, Detterbeck FC, Marino M, Nicholson AG, Huang J, Strobel P, Antonicelli A, Marx A. 2015. The impact of thymoma histotype on prognosis in a worldwide database. J Thorac Oncol. 10:367–372.
   PubMed Web of Science ®Google Scholar
• Weksler B, Nason KS, Mackey D, Gallagher A, Pennathur A. 2012. Thymomas and extrathymic cancers. Ann Thorac Surg. 93:884–888.
   PubMed Web of Science ®Google Scholar
• Weksler B, Pennathur A, Sullivan JL, Nason KS. 2015. Resection of thymoma should include nodal sampling. J Thorac Cardiovasc Surg. 149:737–742.
   PubMed Web of Science ®Google Scholar
• Weksler B, Shende M, Nason KS, Gallagher A, Ferson PF, Pennathur A. 2012. The role of adjuvant radiation therapy for resected stage III thymoma: a population-based study. Ann Thorac Surg. 93:1822–1828; discussion 1828–1829.
   PubMed Web of Science ®Google Scholar
• Zhou D, Deng XF, Liu QX, Zheng H, Min JX, Dai JG. 2016. The effectiveness of postoperative radiotherapy in patients with completely resected thymoma: a meta-analysis. Ann Thorac Surg. 101:305–310.
   PubMed Web of Science ®Google Scholar