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Original Article

Changes in Frequencies of Chromosomal Aberrations and Sister Chromatid Exchanges during Confluent Holding Recovery in X-irradiated Normal Human Diploid Fibroblasts

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Pages 597-602 | Received 28 Dec 1984, Accepted 18 Mar 1984, Published online: 03 Jul 2009

References

  • Chan G.L., Little J.B. Induction of oncogenic transformation in vitro by ultraviolet light. Nature 1976; 264: 442–444
  • Cox R., Masson W.K., Weichselbaum R.R., Nove J., Little J.B. The repair of potentially lethal damage in X-irradiated cultures of normal and Ataxia telangiectasia human fibroblasts. International Journal of Radiation Biology 1981; 39: 357–365
  • Chan G.L., Nagasawa H., Little J.B. Induction and repair of lethal and oncogenic lesions and their relationship to cytogenetic changes in UV-irradiated mouse 10T1/2 cells. Radiation Research, S. Okada, M. Imamura, T. Terasima, M. Yamaguchi. Japanese Association for Radiation Research, Tokyo 1979; 603–609
  • Fornace A.J., Nagasawa H., Little J.B. Relationship of DNA repair to chromosome aberrations, sister chromatid exchanges and survival during liquid holding recovery in X-irradiated mammalian cells. Mutation Research 1980; 70: 323–336
  • Grosovsky A.J., Little J.B. Confluent holding leads to a transient enhancement in mutagenesis in UV-light-irradiated Xeroderma pigmentosum, Gardner's syndrome and normal human diploid fibroblasts. Mutation Research 1985; 149: 147–155
  • Nagasawa H., Little J.B. Induction of chromosome aberrations and sister chromatid exchanges by X-rays in density-inhibited cultures of mouse 10T1/2 cells. Radiation Research 1981; 87: 538–551
  • Nagasawa H., Fornace A.J., Jr., Ritter M.A., Little J.B. Relationship of enhanced survival during confluent holding recovery in ultraviolet-irradiated human and mouse cells to chromosome aberrations, sister chromatid exhcanges, and DNA repair. Radiation Research 1982; 92: 483–496
  • Nagasawa H., Little J.B. Comparison of kinetics of X-ray induced cell killing in normal, Ataxia telangiectasia and hereditary retinoblastoma fibroblasts. Mutation Research 1983; 109: 297–308
  • Nagasawa H., Latt S.A., Lalande M.E., Little J.B. Effects of X-irradiation on cell-cycle progression, induction of chromosomal aberrations and cell killing in Ataxia telangiectasia (AT) fibroblasts. Mutation Research 1985; 148: 71–82
  • Ritter M.A., Cleaver J.E., Tobias C.A. High LET radiations induce a large proportion of non-rejoining DNA breaks. Nature 1977; 266: 653–655
  • Sakai K., Okada S. Radiation-induced DNA damage and cellular lethality in cultured mammalian cells. Radiation Research 1984; 98: 479–490
  • Terzaghi M., Little J.B. Repair of potentially lethal radiation damage in mammalian cells is associated with enhancement of malignant transformation. Nature 1975; 253: 548–549
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  • Weichselbaum R.R., Nove J., Little J.B. Deficient recovery from potentially lethal radiation damage in Ataxia telangiectasia and Xeroderma pigmentosum. Nature 1978; 271: 261–262

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