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Original Article

Radioprotective Activity of Ethylcellulose Microspheres Containing WR 2721, after Oral Administration

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Pages 21-29 | Received 15 Aug 1986, Accepted 08 Jan 1987, Published online: 03 Jul 2009

References

  • Benita S., Shani D., Abdulrazik M., Samunia. Controlled release of radioprotective agents from matrix tablets-effect of preparative conditions on release rates. Journal of Pharmacy and Pharmacology 1984; 36: 222–228
  • Benoit J.P., Puisieux J.F. Microcapsules and microspheres for embolization and chemoembolization. Polymeric Nanoparticles and Microspheres, P. Guiot, P. Couvreur. C.R.C. Press, Boca Raton 1986; 137–174
  • Brown D.Q., Yuhas J.M., Mackenzie L.J., Graham W.J., Pittock J.W. Differential radioprotection of normal tissues by hydrophilic chemical protectors. International Journal of Radiation, Oncology, Biology, Physics 1984; 10: 1581–1584
  • Davidson D.E., Grenan M.M., Sweeney T.R. Biological characteristics of some improved radioprotectors. Radiation Sensitizers. Their Use in the Clinical Management of Cancer, L.W. Brady. Masson, New York 1980; 309–318
  • Ellman G.L., Courtney K.D., Andres V., Featherstone R.M. A new and rapid colorimetric determination of acetylcholinestrease activity. Biochemical Pharmacology 1961; 7: 88–95
  • Jaskierowicz D., Genissel F., Roman V., Berleur F., Fatome M. Oral administration of liposome-entrapped cysteamine and the distribution pattern in blood, liver and spleen. International Journal of Radiation Biology 1985; 47: 615–619
  • Kato T., Unno K., Goto A. Ethylcellulose microcapsules for selective drug delivery. Methods in Enzymology. Vol. 112. Drug and Enzyme targeting, K.J. Widder, R. Green. Academic Press, New York 1985; 139–150
  • Kligerman M.M., Glover D.J., Turrisi A.T., Norfleet A.L., Yuhas J.M., Coia L.R., Simone C., Glick J.H., Goodman R.L. Toxicity of WR 2721 administered in single and multiple doses. International Journal of Radiation, Oncology, Biology, Physics 1984; 10: 1773–1776
  • Miyazaki S., Hashiguchi N., Sugiyama M., Takada M., Morimoto Y. Fibrinogen microspheres as novel drug delivery system for antitumor drugs. Chemical and Pharmaceutical Bulletin 1986; 34: 1370–1375
  • Pongpaibul Y., Price J.C., Whirworth C.W. Preparation and evaluation of controlled indomethacine microspheres. Drug Development and Industrial Pharmacy 1984; 10: 1597–1616
  • Roman V., Bocquier F., Leterrier F., Fatome M. Action radioprotectice de la cystéamine incorporée dans des liposomes administrés par voie orale à la souris. Comptes rendus Académie des Sciences, Paris 1982; 295: 191–193
  • Salib N.N., El-Menshawy M.E., Ismail A.A. Ethylcellulose as a potential sustained release coating for oral pharmaceuticals. Pharmazie 1976; 31: 721–723
  • Tomlinson E., Burger J.J. Incorporation of water-soluble drugs in albumin microspheres. Methods in Enzymology. Vol. 112. Drug and Enzyme Targeting, K.S. Widder, R. Green. Academic Press, New York 1985; 27–43
  • Tomlinson E., Burger J.J., Schoonderwoerd E.M.A., Mc Vie J.G. Human serum albumin microspheres for intra-arterial drug targeting of cytostatic compounds. Pharmaceutical aspects and release characteristics. Microspheres and Drug Therapy. Pharmaceutical, Immunological and Medical Aspects, S.S. Davies, L. Illum, J.G. McVie, E. Tomlinson. Elsevier, Amsterdam 1984; 75–89
  • Vos O., Roos-Verhey W.S.D. Protection against X-irradiation by some orally administered compounds. International Journal of Radiation Biology 1984; 45: 479–486
  • Weingarten C., Moufi A., Desjeux J.F., Luong T.T., Durand G., Devisaguet J.P., Puisieux F. Oral ingestion of insulin liposomes: effects of the administration route. Life Sciences 1981; 28: 2747–2752
  • Yuhas J.M., Storer J.B. Chemoprotection against three modes of radiation death in the mouse. International Journal of Radiation Biology 1969; 15: 233–237
  • Yuhas J.M. Protective drugs in cancer therapy: optimal testing and future directions. International Journal of Radiation Oncology, Biology, Physics 1982; 8: 513–517
  • Yuhas J.M., Davies M.E., Glover D., Brown D.Q., Ritter M. Circumvention of the tumour membrane barrier to WR 2721 adsorption by reduction of drug hydrophilicity. International Journal of Radiation Oncology, Biology, Physics 1982; 8: 519–522
  • Ziegler D.M., Pouljen L.L., Richerson R.B. Oxidation metabolism of sulfur containing radioprotective agents. Radioprotectors and Anticarcinogens, O.F. Nygaard, M.G. Simic. Academic Press, New York 1983; 191–202

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