8
Views
2
CrossRef citations to date
0
Altmetric
Original Article

Radioprotection of Cultured Cells by Preincubation in Medium Containing Deuterium Oxide

, , &
Pages 165-173 | Received 05 Mar 1990, Accepted 19 Jun 1990, Published online: 03 Jul 2009

References

  • Ben-Hur E., Riklis E. Deuterium oxide enhancement of Chinese hamster cell response to gamma radiation. Radiation Research 1980; 81: 224–235
  • Ben-Hur E., Utsumi H., Elkind M.M. Potentially lethal and DNA radiation damage by medium containing D2O and by hypertonic buffer. Radiation Research 1980; 84: 25–34
  • Biggs M.W., Eiselein J.E., Wilcox G. Observations on murine leukemia treated with deuterium and X-ray. Cancer Research 1963; 23: 1059–1062
  • Buckhold B., Adams R.B., Gregg E.C. Osmotic adaptation of mouse lymphoblasts. Biochimica et Biophysica Acta 1965; 102: 600–608
  • Fielden E.M., Hart E.J. Primary radical yields and some rate constants in heavy water. Radiation Research 1968; 33: 426–436
  • Katz J.J., Crespi H.L., Hasterlik R.J., Thomson J.F., Finkel A.J. Some observations on biological effects of deuterium, with special reference to effects on neoplastic processes. Journal of the National Cancer Institute 1957; 18: 641–659
  • Katz J.J., Crespi H.L., Czajka D.M., Finkel A.J. Course of deuteration and some physiological effects of deuterium in mice. American Journal of Physiology 1962; 205: 907–913
  • Katz J.J., Crespi H.L. Isotope effects in biological systems. Isotope Effects in Chemical Reactions, C.J. Collins, N.S. Bowman. Van Nostrand Reinhold, New York 1970; 286–363
  • Laissue J.A., Bally E., Joel D.D., Slatkin D.N., Stoner D. Protection of mice from whole-body gamma radiation by deuteration of drinking water. Radiation Research 1983; 96: 59–64
  • Laissue J.A., Altermatt H.J., Bally E., Gebbers J.O. Protection of mice from whole body gamma irradiation by deuteration of drinking water: hematologic findings. Experimental Hematology 1987; 15: 177–180
  • Michel F., Altermatt H.J., Gebbers J.O., Bally E., Berchtold W., Laissue J.A. Radioprotection by pretreatment with deuterated water: cytokinetic changes in the small intestine of the mouse. Virchows Archiv B, Cell Pathology 1988; 54: 214–220
  • Schaer J.C., Schindler R. The requirement of mammalian cell cultures for serum proteins. Growth-promoting activity of pepsin-digested serum albumin in different media. Biochimica et Biophysica Acta 1967; 147: 154–161
  • Schindler R. Quantitative colonial growth of mammalian cells in fibrin gels. Experimental Cell Research 1964; 34: 595–598
  • Slatkin D.N., Stoner R.D., Gremme A.M., Fairchild R.G., Laissue J.A. Whole-body irradiation of deuterated mice by the 10B(n,α)7Li reaction. Proceedings of the National Academy of Sciences, U.S.A. 1983; 80: 3480–3484
  • Thomson J.F. Biological Effects of Deuterium. Pergamon, Oxford 1963; 85–112
  • Ueno A.M., Tanaka O., Matsudaira H. Inhibition of gamma-ray dose-rate effects by D2O and inhibitors of poly(ADP-ribose) synthetase in cultured mammalian L5178Y cells. Radiation Research 1984; 98: 574–582
  • Ujeno Y., Takimoto K. Suppression of mammalian cell survival after X- or thermal neutron-irradiation in the presence of deuteriated water or 10B-boric acid. International Journal of Radiation Biology 1983; 43: 675–679
  • Zimmermann A., Schaer J.C., Schneider J., Molo P., Schindler R. Dominant versus recessive behavior of a cold- and a heat-sensitive mammalian cell cycle variant in heterokaryons. Somatic Cell Genetics 1981; 7: 591–601

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.