112
Views
323
CrossRef citations to date
0
Altmetric
Original Article

Internucleosomal DNA Cleavage Should not be the Sole Criterion for Identifying Apoptosis

, , &
Pages 451-453 | Received 13 Nov 1991, Accepted 13 Dec 1991, Published online: 03 Jul 2009

References

  • Alnemri E.S., Litwack G. Activation of internucleosomal DNA cleavage in human CEM lymphocytes by glucocorticoid and novobiocin. Journal of Biological Chemistry 1990; 265: 17323–17333
  • Arends M.J., Morris R.G., Wyllie A.H. Apoptosis. The role of the endonuclease. American Journal of Pathology 1990; 136: 593–608
  • Calderwood S.K., Stevenson M.A., Modlinsky M., Hahn G.M. Binding of polycation DEAE-dextran to Chinese hamster ovary cells induces reversible Ca2+ influx and inhibits capping of concanavalin A acceptor proteins. Biochimica et Biophysica Acta 1986; 889: 316–325
  • Harmon B.V., Corder A.M., Collins R.J., Gobé G.C., Allen J., Allan D.J., Kerr J.F.R. Cell death induced in a murine mastocytoma by 42–47°C heating in vitro: evidence that the form of death changes from apoptosis to necrosis above a critical heat load. International Journal of Radiation Biology 1990; 58: 845–858
  • Kerr J.F.R., Wyllie A.H., Currie A.R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. British Journal of Cancer 1972; 26: 239–357
  • Kerr J.F.R., Harmon B.V. Definition and incidence of apoptosis: an historical perspective. Apoptosis: the Molecular Basis of Cell Death, L.D. Tomei, F.O. Cope. Cold Spring Harbor Laboratory Press, New York 1991; 5–29
  • Lockshin R.A., Alles A., Kodaman N., Zakeri Z.F. Programmed cell death and apoptosis: early DNA degradation does not appear to be prominent in either embryonic cell death or metamorphosis of insects. FASEB Journal 1991; 5: A518–A518
  • McConkey D.J., Hartzell P., Duddy S.K., Håkansson H., Orrenius S. 2,3,7,8-tetrachlorodibenzo-p-dioxin kills immature thymocytes by Ca2+-mediated endonuclease activation. Science 1988; 242: 256–259
  • McConkey D.J., Aguilar-Santelises M., Hartzell P., Eriksson I., Mellstedt H., Orrenius S., Jondal M. Induction of DNA fragmentation in chronic B-lymphocytic leukemia cells. Journal of Immunology 1991; 146: 1072–1076
  • Newell M.K., Haughn L.J., Maroun C.R., Julius M.H. Death of mature T cells by separate ligation of CD4 and T-cell receptor for antigen. Nature 1990; 347: 286–288
  • Orrenius S., McConkey D.J., Bellomo G., Nicotera P. Role of Ca2+ in toxic cell killing. Trends in Pharmacological Science 1989; 10: 281–285
  • Smith C.A., Williams G.T., Kingston R., Jenkinson E.J., Owen J.J.T. Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures. Nature 1989; 337: 181–184
  • Tomei L.D. Apoptosis: a program for death or survival?. Apoptosis: the Molecular Basis of Cell Death, L.D. Tomei, F.O. Cope. Cold Spring Harbor Laboratory Press, New York 1991; 279–316
  • Wyllie A.H. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 1980; 284: 555–556
  • Wyllie A.H., Morris R.G., Smith A.L., Dunlop D. Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis. Journal of Pathology 1984; 142: 67–77

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.