26
Views
28
CrossRef citations to date
0
Altmetric
Original Article

Late T Cell Deficiency in Victims of the Chernobyl Radiation Accident: Possible Mechanisms of Induction

, , , , , & show all
Pages 519-528 | Received 26 May 1992, Accepted 09 Oct 1992, Published online: 03 Jul 2009

References

  • Akiyama M., Zhou O.L., Kusunoki Y., Kyoizumi S., Kohno N., Akiba S., Delongchamp R.R. Age and dose-related alteration of in vitro mixed lymphocyte culture response of blood lymphocytes from A-bomb survivors. Radiation Research 1989; 117: 26–34
  • Amagai T., Kina T., Hirokawa K.-I., Nishikawa S.-I., Imanishi J., Katsura Y. Dysfunction of irradiated thymus for the development of helper T cells. Journal of Immunology 1987; 139: 358–364
  • Bach J.F., Dardenne M. Studies on thymus products. II. Demonstration and characterization of a circulating thymic hormone. Immunology 1973; 25: 353–357
  • Barabanova A.V., Baranov A.E., Gus'kova A.K., Gruzdev G.P., Pyatkin E.K. Acute Radiation Effects in Humans. Atomizdat, Moscow 1986, in Russian
  • Baryshnikov, A.Y., Tupicin, N.N., Kryczanov, M.A., et al. Panel of monoclonal antibodies and antisera for dignoses of human haemoblastoses. Doklady Akademii Nauk SSSR 1985; 282: 753–759
  • Bebeshko V.G., Chumak A.A., Bazyka D.A., Khal'avka I.G., Savran A.A., Belyaeva N.V., Tsiva S.A., Prakhova V.K. Immunological monitoring of patients with acute radiation sickness 12–36 months after disaster on Chernobyl. NPP Meditsinskaya Radiologiya 1990; 35: 27–30, (in Russian)
  • Belyakov I.M., Yarilin A.A., Nadegyna N.M. The state of the immune system of men five years after being affected by factors of radiation disaster. Radiobiologiya 1992; 41: 42–47, (in Russian)
  • Boyum A. Separation of leukocytes from blood and bone marrow. Scandinavian Journal of Clinical and Laboratory Investigation 1968; 21: 77–89
  • Chumak A.A., Bazyka D.A., Tal'ko V.V., Minchenko J.N., Bespalenko A.G., Belyaeva N.V., Gerasimenko N.K., Dmitrenko E.A., Konopleva Y.L., Nefedova P.A., Prakhova V.K., Savran A.V., Tsiva S.A. Immunological aspects in the study of subjects exposed to ionizing radiation during the accident at the Chernobyl Atomic Power Station. Vestnik Akademii Medicinskikh Nauk SSSR 1991; 8: 16–20, (in Russian)
  • Drobyshevskaya E.I., Nesterenko V.G., Spitsyn S.V., Nedyalkov Yu.A. Induction of tissue-specific and multi-specific monoclonal antibodies in immunization with microbe antigens. Immunologiya 1990; 3: 48–52, (in Russian)
  • Filatov A.V., Bachurin P.S., Markova N.A. Panel of monoclonal antibodies against antigens of human lymphocytes. Experimentalnaya Oncologiya 1989; 2: 24–27, (in Russian)
  • Filatov A.V., Scherbukhin V.V., Bachurin P.S., Yartsev M.N. Two-colour flow cytometry study of lymphocyte subpopulation in patients with primary immunodeficiencies. Biomedical Science 1991; 2: 88–96
  • Gus'kova A.K., Baranov A.E., Barabanova A.V., Grusdev G.P., Pyatkin E.K., Nadezhina N.M., Metlyaeva N.A., Selidovkin G.D., Gusev I.A., Moiseev A.A., Dorofeeva E.M., Zykova I.E., Konchalovsky M.V. Acute radiation effects in victims of the Chernobyl N.P.P. accident. Meditsinskaya Radiologiya 1987; 32: 3–18, (in Russian)
  • Hirokawa K., Sado T. Radiation effects on regeneration and T cell inducing function of the thymus. Cellular Immunology 1984; 84: 372–379
  • Incefy G.S., Ishimura K., Wang J.G., Unson C.G., Erickson B.W. A radioimmunoassay for thymosin alpha-1. Journal of Immunological Methods 1986; 89: 9–17
  • Kay M.M.B. Effect of age on T cell differentiation. Federation Proceedings 1978; 37: 1241–1244
  • Kraft R., Frankhauser G., Gerber H., Hess W., Cottier H. Age-related involution and terminal disorganization of the human thymus. International Journal of Radiation Biology 1988; 53: 169–176
  • Kusunoki Y., Akiyama M., Kyoizumi S., Bloom E.T., Makinodan T. Age-related alteration in the composition of immunocompetent blood cells in atomic bomb survivors. International Journal of Radiation Biology 1988; 53: 189–198
  • Lauria F., Foa R., Gobbi M., Camasdulla C., Lusso P., Raspadori D., Tura S. Increased proportion of suppressor/cytotoxic (OKT8+) cells in patients with Hodgkin's disease in long-lasting remission. Cancer 1983; 52: 1385–1388
  • Lyampert I.M. Autoantibodies reacting with skin basal epithelium and endocrine epithelium of thymus. First stage of development of various autoimmune processes. Immunologiya 1988; 4: 5–9, (in Russian)
  • Manori I., Kushilevsky A., Segal S., Weinstein Y. Radiosensitivity of isolated subsets of human lymphocytes (E+, OKT4+, OKT8+): protective role of monocytes and monokines. Clinical and Experimental Immunology 1984; 58: 453–461
  • Martynenko S.V., Grinevich Y.A., Baraboi V.A., Gulko G.M. A comparative study of the effect of X-rays and fast neutrons on endocrine thymus function. Radiobiologiya 1989; 29: 268–271, (in Russian)
  • Nakamura N., Kusunoki Y., Akiyama M. Radiosensitivity of CD4 and CD8 positive human T lymphocytes by an in vitro colony formation assay. Radiation Research 1990; 123: 224–227
  • Petrov R.V., Oradovskaya I.V., Pinegin B.V. Program of long-term immunological monitoring of population group exposed to risk factors at the Chernobyl accident. Meditsinskay Radiologiya 1991; 1: 39–42, (in Russian)
  • Rinaldi-Garaci C., Gobbo V.D., Favalli C., Garaci E., Bistoni F., Jaffe B.M. Induction of serum thymic-like activity in adult thymectomized mice by a synthetic analogue of PGE2. Cellular Immunology 1982; 72: 97–101
  • Rotstein S., Blomgren H., Petrini B., Wasserman J., Baral E. Long-term effects on the immune system following local radiation therapy for breast cancer. I. Cellular composition of the peripheral blood lymphocyte population. International Journal of Radiation Oncology, Biology and Physics 1985; 11: 921–925
  • Sado T., Kamisaki H., Ikarashi J., Kubo E. Immediate and long-term effects of radiation on the immune system of specific pathogen-free mice. International Journal of Radiation Biology 1988; 53: 177–187
  • Sharp J.G., Watkins E.B. Cellular and immunological consequences of thymic irradiation. Immunopharmacologic Effects of Radiation Therapy, J.B. Dubois, B. Serron, C. Rosenfeld. Raven Press, New York 1981; 137–179, In
  • Silagadze D.G., Beletskaya L.V., Drobyshevskaya E.L., Chelidze P.V., Abyzov V.N., Lyampert I.M. The reaction of monoclonal antibodies A 6/1 with the antigen determination of squamous cell carcinoma ultrastructures. Bulleten Experimentalnov Biologii i Meditsini 1987; 104: 488–490, (in Russian)
  • Smirnov V.S., Vaschenko V.I., Morozov F.G. Immune system status in subjects two years after the action of radiation catastrophe factors. Immunologiya 1990; 6: 63–65, (in Russian)
  • Wiedmeier S.E., Samlowski W.E., Rasmussen C.J., Huang K., Daynes R.A. Effect of ionizing radiation on thymic epithelial cell function. I. Radiation-spared thymic epithelial grafts expedite the recovery of T cell function in lethally irradiated and fetal liver reconstituted mice. Journal of Immunology 1988; 140: 21–29
  • Yialouris Y., Evangelatos G.P., Soteriadis-Vlahos C. The identification of prothymosin alfa-like material in vertebrate lymphoid organs by a radioimmunoassay. Journal of Immunological Methods 1988; 106: 267–275

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.