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Original Article

An Image Analysis Technique for Detection of Radiation-induced DNA Fragmentation after CHEF Electrophoresis

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Pages 245-249 | Received 07 Jan 1993, Accepted 22 Apr 1993, Published online: 03 Jul 2009

References

  • Blöcher D. In CHEF electrophoresis a linear induction of DSB corresponds to a nonlinear fraction of extracted DNA with dose. International Journal of Radiation Biology 1990; 57: 7–12
  • Blöcher D., Kuhni M. DNA double-strand break analysis by CHEF electrophoresis. International Journal of Radiation Biology 1990; 58: 23–34
  • Elia M.C., Deluca J.G., Bradley M.O. Significance and measurement of DNA double-strand breaks in mammalian cells. Pharmacology Theory 1991; 51: 291–327
  • Rosemann M., Peacock J., McMillan T.J., Kampinga H.H., Konings A.W.T. Analysis of the dose response curve for DNA fragmentation after ionizing radiation as detected by pulsed field gel electrophoresis. 1993, (Submitted)
  • Smeets M.A., Mooren E.H.M., Begg A.C. Radiation-induced DNA damage and repair in radiosensitive and radioresistant human tumour cells measured by field inversion gel electrophoresis. International Journal of Radiation Biology 1993; 63: 703–714
  • Stamato T.S., Denki N. Asymmetric field inversion gel electrohoresis: A new method for detecting DNA double-strand breaks in mammalian cells. Radiation Research 1990; 121: 196–205

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