16
Views
58
CrossRef citations to date
0
Altmetric
Original Article

DNA Base Damage Generated in Vivo in Hepatic Chromatin of Mice Upon Whole Body γ-irradiation

, &
Pages 645-650 | Received 11 Jun 1993, Accepted 30 Aug 1993, Published online: 03 Jul 2009

References

  • Boiteux S., Gajewski E., Laval J., Dizdaroglu M. Substrate specificity of the Escherichia coli Fpg protein (formamidopyrimidine-DNA glycosylase): excision of purine lesions in DNA produced by ionizing radiation or photosensitization. Biochemistry 1992; 31: 106–110
  • Breimer L.H. Molecular mechanisms of oxygen radical carcinogenesis and mutagenesis: the role of DNA base damage. Molecular Carcinogenesis 1990; 3: 188–197
  • Chapman J.D., Reuvers A.P., Borsa J., Greenstock C.L. Chemical radioprotection and radiosensitization of mammalian cells growing in vitro. Radiation Research 1973; 56: 291–306
  • Claycamp H.G., Ho K.-K. Background and radiation-induced 8-hydroxy-2′-deoxyguanosine in γ-irradiated Escherichia coli. International Journal of Radiation Biology 1993; 63: 597–607
  • Cullis P.M., Jones G.D.D., Symons M.C.R., Lea J.S. Electron transfer from protein to DNA irradiated chromatin. Nature 1987; 330: 773–774
  • Deeble D.J., Schuchmann M.N., Steenken S., von Sonntag C. Direct evidence for the formation of thymine radical cations from the reaction of SO.-4 with thymine derivatives: a pulse radiolysis study with optical and conductive detection. Journal of Physical Chemistry 1990; 94: 8186–8192
  • Dizdaroglu M. Oxidative damage to mammalian chromatin. Mutation Research 1992; 275: 331–342
  • Dizdaroglu M. Quantitative determination of oxidative base damage in DNA by stable isotope-dilution mass spectrometry. FEBS Letters 1993; 315: 1–6
  • Dizdaroglu M., Hermes W., Schulte-Frohlinde D., von Sonntag C. Enzymatic digestion of DNA irradiated in aqueous solution. Separation of the digests by ion-exchange chromatography. International Journal of Radiation Biology 1978; 33: 563–569
  • Djuric Z., Heilbrun L.K., Reading B.A., Boomer A., Valeriote F.A., Martino S. Effects of a low-fat diet on levels of oxidative damage to DNA in human peripheral nucleated blood cells. Journal of the National Cancer Institute 1991; 83: 766–769
  • Floyd R.A., West M.S., Eneff K.L., Schneider J.E., Wong P.K., Tingey D.T., Hogsett W.E. Conditions influencing yield and analysis of 8-hydroxy-2′-deoxyguanosine on oxidatively damaged DNA. Analytical Biochemistry 1990; 188: 155–158
  • Frenkel K., Zhong Z., Wei H., Karkoszka J., Patel U., Rashid K., Georgescu M., Solomon J.J. Quantitative high performance liquid chromatographic analysis of DNA oxidized in vitro and in vivo. Analytical Biochemistry 1991; 196: 126–136
  • Fuciarelli A.F., Wegher B.J., Gajewski E., Dizdaroglu M., Blakely W.F. Quantitative measurement of radiation-induced base products in DNA using gas chromatography-mass spectrometry. Radiation Research 1989; 119: 219–231
  • Gajewski E., Rao G., Nackerdien Z., Dizdaroglu M. Modification of DNA bases in mammalian chromatin by radiation-generated free radicals. Biochemistry 1990; 29: 7876–7882
  • Halliwell B., Dizdaroglu M. The measurement of oxidative damage to DNA by HPLC and GC/MS techniques. Free Radical Research Communications 1992; 16: 75–87
  • Halliwell B., Gutteridge J.M.C. Role of free radicals and catalytic metal ions in human disease: an overview. Methods in Enzymology 1990; 186: 1–85
  • Kasai H., Crain P.F., Kuchino Y., Nishimura S., Ootsuyama A., Tanooka H. Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair. Carcinogenesis 1986; 7: 1849–1851
  • Kasai H., Yamaizumi Z., Berger M., Cadet J. Photosensitized formation of 7,8-dihydro-8-oxo-2′-deoxyguanosine (8-hydroxy-2′-deoxyguanosine) in DNA by riboflavin: a non-singlet oxygen mediated reaction. Journal of the American Chemical Society 1992; 114: 9692–9694
  • Kasprzak K.S., Diwan B.A., Rice J.M., Misra M., Riggs C.W., Olinski R., Dizdaroglu M. Nickel(II)-mediated oxidative DNA base damage in renal and hepatic chromatin of pregnant rats and their fetuses. Possible relevance to carcinogenesis. Chemical Research in Toxicology 1992; 7: 809–815
  • MacCubbin A.E., Evans M.S., Paul C.R., Budzinski E.E., Przybyszewki J., Box H.C. Enzymatic excision of radiation-induced lesions from DNA model compounds. Radiation Research 1991; 126: 21–26
  • MacCubbin A.E., Evans M.S., Budzinski E.E., Wallace J.C., Box H.C. Characterization of two radiation-induced lesions from DNA: studies using nuclease P1. International Journal of Radiation Biology 1992; 61: 729–736
  • Nackerdien Z., Olinski R., Dizdaroglu M. DNA base damage in chromatin of γ-irradiated cultured human cells. Free Radical Research Communications 1992; 16: 259–273
  • Oleinick N.L., Chiu S., Ramakrishnan N., Xue L. The formation, identification, and significance of DNA-protein cross-links in mammalian cells. British Journal of Cancer 1987; 55(Suppl. VIII)135–140
  • Roots R., Okada S. Protection of DNA molecules of cultured mammalian cells from radiation-induced single-strand scissions by various alcohols and SH compounds. International Journal of Radiation Biology 1972; 21: 329–342
  • Roots R., Okada S. Estimation of life times and diffusion distances of radicals involved in X-ray-induced DNA strand breaks or killing of mammalian cells. Radiation Research 1975; 64: 306–320
  • Sancar A., Sancar G.B. DNA repair enzymes. Annual Reviews in Biochemistry 1988; 57: 29–67
  • Steenken S. Purine bases, nucleosides, and nucleotides: aqueous solution redox chemistry and transformation reactions of their radical cations and e- and OH adducts. Chemical Reviews 1989; 89: 503–520
  • Téoule R. Radiation-induced DNA damage and its repair. International Journal of Radiation Biology 1987; 51: 573–589
  • von Sonntag C. The Chemical Basis of Radiation Biology. Taylor & Francis, New York 1987; 94–166
  • Wagner J.R., van Lier J.E., Berger M., Cadet J. Photodynamic methods for oxy radical-induced DNA damage. Methods in Enzymology 1990; 186: 502–511
  • Ward J. The yield of DNA double-strand breaks produced intracellularly by ionizing radiation: a review. International Journal of Radiation Biology 1990; 57: 1141–1150
  • Ward J. Mechanisms of radiation action on DNA in model systems—their relevance to cellular DNA. The Early Effects of Radiation on DNA, E.M. Fielden, P. O'Neill. Springer-Verlag, Berlin 1991; 1–16, In
  • Watson J.T. Selected-ion measurements. Methods in Enzymology 1990; 193: 86–106

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.