Radiation-induced Genomic Instability

References

• Alvarez L., Evans J.W., Wilks R., Lucas J.N., Brown J.M., Giaccia A.J. Chromosomal radiosensitivity at intrachromosomal telomeric sites. Genes, Chromosomes and Cancer 1993; 8: 8–14
   PubMed Web of Science ®Google Scholar
• Born R., Trott K.R. Clonogenicity of the progeny of surviving cells after irradiation. International Journal of Radiation Biology 1988; 53: 319–330
   Web of Science ®Google Scholar
• Bronner C.E., Baker S.M., Morrison P.T., Warren G., Smith L.G., Lescoe M.K., Kane M., Earabino C., Lipford J., Lindblom A., Tannergård P., Bollag R.J., Godwin A.R., Ward D.C., Nordenskjøld M., Fishel R., Kolodner R., Liskay R.M. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 1994; 368: 258–261
   PubMed Web of Science ®Google Scholar
• Chang W.P., Little J.B. Delayed reproductive death in X-irradiated Chinese hamster ovary cells. International Journal of Radiation Biology 1991; 60: 483–496
   PubMed Web of Science ®Google Scholar
• Chang W.P., Little J.B. Evidence that DNA double-strand breaks initiate the phenotype of delayed reproductive death in Chinese hamster ovary cells. Radiation Research 1992a; 131: 53–59
   PubMed Web of Science ®Google Scholar
• Chang W.P., Little J.B. Delayed reproductive death as a dominant phenotype in cell clones surviving X-irradiation. Carcinogenesis 1992b; 13: 923–928
   PubMed Web of Science ®Google Scholar
• Chang W.P., Little J.B. Persistently elevated frequency of spontaneous mutations in progeny of CHO clones surviving X-irradiation: association with delayed reproductive death. Mutation Research 1992c; 270: 191–199
   PubMed Web of Science ®Google Scholar
• Clarke A.R., Purdie F.A., Harrison D.J., Morris R.G., Bird C.C., Hooper M.L., Wyllie A.H. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 1993; 362: 849–852
   PubMed Web of Science ®Google Scholar
• Cox R. Molecular mechanisms of radiation oncogenesis. International Journal of Radiation Biology 1994; 65: 57–64
   PubMed Web of Science ®Google Scholar
• Crompton N.E., Barth B., Kiefer J. Inverse dose-rate effect for the induction of 6-thioguanine-resistant mutants in Chinese hamster V79-S cells by 60Co gamma rays. Radiation Research 1990; 124: 300–308
   PubMed Web of Science ®Google Scholar
• Donehower L.A., Harvey M., Slagle B.L., McArthur M.J., Montgomery C.A., Jr., Butel J.S., Bradley A. Mice deficient in p53 are developmentally normal but susceptible to spontaneous tumors. Nature 1992; 356: 215–221
   PubMed Web of Science ®Google Scholar
• El-Deiry W., Harper J.W., O'Connor P.M., Velculescu V.E., Canman C.E., Jackman J., Pietenpol J.A., Burrell M., Hill D.E., Wang Y., Wiman K.G., Merger W.E., Kastan M.B., Kohn K.W., Elledge S.J., Kinzler K.W., Vogelstein B. WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis. Cancer Research 1994; 54: 1169–1174
   PubMed Web of Science ®Google Scholar
• Fabre F. Mitotic transmission of induced recombinational ability in yeast. Cellular Responses to DNA Damage, E. Friedberg. Liss, New York 1983; 379–384, In
   Google Scholar
• Fabre F., Roman H. Genetic evidence for inducibility of recombination competence in yeast. Proceedings of the National Academy of Sciences USA 1977; 74: 1667–1671
   PubMed Web of Science ®Google Scholar
• Fishel R., Lescoe M.K., Rao M.R., Copeland N.G., Jenkins N.A., Garber J., Kane M., Kolodner R. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 1993; 75: 1027–1038
   PubMed Web of Science ®Google Scholar
• Game J.C. DNA double-strand breaks and the RAD50-RAD57 genes in Saccharomyces. Seminars in Cancer Biology 1993; 4: 73–83
   PubMed Web of Science ®Google Scholar
• Gorgojo L., Little J.B. Expression of lethal mutations in progeny of irradiated mammalian cells. International Journal of Radiation Biology 1989; 55: 619–630
   PubMed Web of Science ®Google Scholar
• Hockenbery D., Nunez G., Milliman C., Schreiber R.D., Korsmeyer S.J. Bel-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 1990; 348: 334–336
   PubMed Web of Science ®Google Scholar
• Holmberg K., Fält S., Johnsson A., Lambert B. Clonal chromosome aberrations and genomic instability in X-irradiated human T-lymphocyte cultures. Mutation Research 1993; 286: 321–330
   PubMed Web of Science ®Google Scholar
• Jeggo P.A., Kemp L.M. X-ray-sensitive mutants of Chinese hamster ovary cell line. Isolation and cross-sensitivity to other DNA-damaging agents. Mutation Research 1983; 112: 313–327
   PubMed Web of Science ®Google Scholar
• Kadhim M.A., MacDonald D.A., Goodhead D.T., Lorimore S.A., Marsden S.J., Wright E.G. Transmission of chromosomal instability after plutonium α-particle irradiation. Nature 1992; 355: 738–740
   PubMed Web of Science ®Google Scholar
• Kastan M.B., Onyekwere O., Sidransky D., Vogelstein B., Craig R.W. Participation of p53 protein in the cellular response to DNA damage. Cancer Research 1991; 51: 6304–6311
   PubMed Web of Science ®Google Scholar
• Kastan M.B., Zhan Q., El-Deiry W.S., Carrier F., Jacks T., Walsh W.V., Plunkett B.S., Vogelstein B., Fornace A.J., Jr. A mammalian cell cycle checkpoint pathway utilizing p53 and GaDD45 is defective in ataxia-telangiectasia. Cell 1992; 71: 587–597
   PubMed Web of Science ®Google Scholar
• Kennedy A.R., Fox M., Murphy G., Little J.B. Relationship between X-ray exposure and malignant transformation in C3H10T½ cells. Proceedings of the National Academy of Sciences, USA 1980; 77: 7262–7266
   PubMed Web of Science ®Google Scholar
• Kennedy A.R., Little J.B. Evidence that a second event in X-ray-induced oncogenic transformation in vitro occurs during cellular proliferation. Radiation Research 1984; 99: 228–248
   PubMed Web of Science ®Google Scholar
• Kronenberg A., Little J.B. Mutagenic properties of low doses of X-rays, fast neutrons, and selected heavy ions in human cells. Low Dose Radiation: Biological Bases of Risk Assessment, K.F. Baverstock, J.W. Stather. Taylor & Francis, London 1989a; 554–559, In
   Google Scholar
• Kronenberg A., Little J.B. Molecular characterization of thymidine kinase mutants of human cells induced by densely ionizing radiation. Mutation Research 1989b; 211: 215–224
   PubMedGoogle Scholar
• Kuerbitz S.J., Plunkett B.S., Walsh W.V., Kastan M.B. Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proceedings of the National Academy of Sciences, USA 1992; 89: 7491–7495
   PubMed Web of Science ®Google Scholar
• Ladanyi M., Cha C., Lewis R., Jhanwar S.C., Huvos A.G., Healy J.H. MDM2 gene amplification in metastatic osteosarcoma. Cancer Research 1993; 53: 16–18
   PubMed Web of Science ®Google Scholar
• Leach F.S., Nicolaides N.C., Papadopoulos N., Liu B., Jen J., Parsons R., Peltomaki P., Sistonen P., Aaltonen L.A., Nystrom-Lahti M., Guan X.-Y., Zhang J., Meltzer P.S., Yu I.-N., Kao F.-T., Chen D.J., Cerosaletti K.M., Fournier R.E.K., Todd S., Lewis T., Leach R.J., Naylor S.L., Weissenbach J., Mecklin J.-P., Järviner H., Petersen G.M., Hamilton S.R., Green J., Jass J., Watson P., Lynch H.T., Trent J.M., de la Chapelle A., Kinzler K., Vogelstein B. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 1993; 75: 1215–1225
   PubMed Web of Science ®Google Scholar
• Lee J.M., Bernstein A. p53 mutations increase resistance to ionizing radiation. Proceedings of the National Academy of Sciences, USA 1993; 90: 5742–5746
   PubMed Web of Science ®Google Scholar
• Li C.Y., Yandell D.W., Little J.B. Evidence for coincident mutations in human lymphoblast clones selected for functional loss of a thymidine kinase gene. Molecular Carcinogenesis 1992; 5: 270–277
   PubMed Web of Science ®Google Scholar
• Little J.B., Gorgojo L., Vetrovs H. Delayed appearance of lethal and specific gene mutations in irradiated mammalian cells. International Journal of Radiation Oncology 1990; 19: 1425–1429
   Web of Science ®Google Scholar
• Livingstone L.R., White A., Sprouse J., Livanos E., Jacks T., Tlsty T.D. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell 1992; 70: 923–935
   PubMed Web of Science ®Google Scholar
• Lowe S.W., Schmitt E.M., Smith S.W., Osborne B.A., Jacks T. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 1993; 362: 847–849
   PubMed Web of Science ®Google Scholar
• Malkin D., Li F.P., Strong L.C., Fraumeni J.F., Nelson C.M., Kim D.H., Kassel J., Gryka M.A., Bischoff F.Z., Tainsky M.A., Friend S.H. Germline p53 mutations in a familial syndrome of breast cancer, sarcomas and other neoplasias. Science 1990; 250: 1233–1238
   PubMed Web of Science ®Google Scholar
• Maltzman W., Czyzyk L. UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells. Molecular and Cellular Biology 1984; 4: 1689–1694
   PubMed Web of Science ®Google Scholar
• Marin G., Bender M.A. Radiation-induced mammalian cell death: lapse-time cinemicrographic observations. Experimental Cell Research 1963; 43: 412–423
   Google Scholar
• Martins M.B., Sabatier L., Ricoul M., Pinton A., Dutrillaux B. Specific chromosome instability induced by heavy ions: a step towards transformation of human fibroblasts?. Mutation Research, 285: 229–237
   PubMedGoogle Scholar
• Marder B.A., Morgan W.F. Delayed chromosomal instability induced by DNA damage. Molecular and Cellular Biology 1993; 13: 6667–6677
   PubMed Web of Science ®Google Scholar
• Mendonca M.S., Kurohara W., Antoniono R., Redpath J.L. Plating efficiency as a function of time postirradiation: evidence for the delayed expression of lethal mutations. Radiation Research 1989; 119: 387–393
   PubMed Web of Science ®Google Scholar
• Mihara K., Bai L., Kano Y., Miyazaki M., Namba M. Malignant transformation of human fibroblasts previously immortalized with 60Co gamma rays. International Journal of Cancer 1992; 50: 639–643
   PubMed Web of Science ®Google Scholar
• Miles C., Sargent G., Phear G., Meuth M. DNA sequence analysis of gamma-radiation-induced deletions and insertions at the APRT locus of hamster cells. Molecular Carcinogenesis 1991; 3: 233–242
   Web of Science ®Google Scholar
• Morris T., Thacker J. Formation of large deletions by illegitimate recombination in the HPRT gene of primary human fibroblasts. Proceedings of the National Academy of Sciences, USA 1993; 90: 1392–1396
   PubMed Web of Science ®Google Scholar
• Mothersill C., Seymour C.B. The influence of lethal mutations on the quantification of radiation transformation frequencies. International Journal of Radiation Biology 1987; 51: 723–729
   Web of Science ®Google Scholar
• Nias A.H.W., Gilbert C.W., Lajtha L.G., Lange C.S. Clone-size analysis in the study of cell growth following single or during continuous irradiation. International Journal of Radiation Biology 1965; 9: 275–290
   Web of Science ®Google Scholar
• Oliner J.D., Kinzler K.W., Meltzar P.S., George D.L., Vogelstein B. Amplification of a gene encoding a p53 associated protein in human sarcomas. Nature 1992; 358: 80–83
   PubMed Web of Science ®Google Scholar
• Papadopoulos N., Nicolaides N.C., Wei Y.F., Ruben S.M., Carter K.C., Rosen C.A., Haseltine W.A., Fleischmann R.D., Fraser C.M., Adams M.D., Venter J.C., Hamilton S.R., Petersen G.M., Watson P., Lynch H.T., Peltomäki P., Mecklin J.-P., de la Chapelle A., Kinzler K.W., Vogelstein B. Mutation of a mutL homolog in hereditary colon cancer. Science 1994; 263: 1625–1629
   PubMed Web of Science ®Google Scholar
• Paquette B., Little J.B. Genomic rearrangements in mouse C3H/10T1/2 cells transformed by X-rays, UVC, and 3-methylcholanthrene, detected by a DNA fingerprint assay. Cancer Research 1992; 52: 5788–5793
   PubMed Web of Science ®Google Scholar
• Pereira-Smith O.M., Smith J.R. Genetic analysis of indefinite division in human cells: identification of four complementation groups. Proceedings of the National Academy of Sciences, USA 1988; 85: 6042–6046
   PubMed Web of Science ®Google Scholar
• Puck T.T., Marcus P.I. Action of x-rays on mammalian cells. Journal of Experimental Medicine 1956; 103: 653–666
   PubMed Web of Science ®Google Scholar
• Sabatier L., Dutrillaux B., Martin M.B. Chromosomal instability. Nature 1992; 357: 548–548
   PubMed Web of Science ®Google Scholar
• Sadamoto S., Suzuki S., Kamiya K., Kominami R., Dohi K., Niwa O. Radiation induction of germline mutation at a hypervariable mouse minisatellite locus. International Journal of Radiation Biology 1994; 65: 549–557
   PubMed Web of Science ®Google Scholar
• Seymour C.B., Mothersill C. Lethal mutations, the survival curve shoulder and split-dose recovery. International Journal of Radiation Biology 1989; 56: 999–1010
   PubMed Web of Science ®Google Scholar
• Seymour C.B., Mothersill C., Alper T. High yields of lethal mutations in somatic mammalian cells that survive ionizing radiation. International Journal of Radiation Biology 1986; 50: 167–179
   Web of Science ®Google Scholar
• Shinohara A., Ogawa H., Matsuda Y., Ushio N., Ikeo K., Ogawa T. Cloning of human, mouse, and fission yeast recombination genes homologous to RAD51 and recA. Nature Genetics 1993; 4: 239–243
   PubMed Web of Science ®Google Scholar
• Sinclair W.K. X-ray induced heritable damage (small-colony formation) in cultured mammalian cells. Radiation Research 1964; 21: 584–611
   PubMed Web of Science ®Google Scholar
• Silver A., Cox R. Telomere-like DNA polymorphisms associated with genetic predisposition to acute myeloid leukemia in irradiated CBA mice. Proceedings of the National Academy of Sciences, USA 1993; 90: 1407–1410
   PubMed Web of Science ®Google Scholar
• Slichenmeyer W.J., Nelson W.G., Slebos R.J., Kastan M.B. Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage. Cancer Research 1993; 53: 4164–4168
   PubMed Web of Science ®Google Scholar
• Srivastava S., Zou Z., Pirollo K., Blattner W., Chang E.H. Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome. Nature 1990; 348: 747–749
   PubMed Web of Science ®Google Scholar
• Stamato T., Weinstein R., Peters B., Hu J., Doherty B., Giaccia A. Delayed mutation in chinese hamster cells. Somatic Cell Molecular Genetics 1987; 13: 57–66
   PubMedGoogle Scholar
• Takahashi E., Matsuda Y., Hori T., Yasuda N., Tsuji S., Mori M., Yoshimura Y., Yamamoto A., Morita T., Matsushiro A. Chromosome mapping of the human (recA) and mouse (recA) homologs of the yeast RAD51 and Escherichia coli recA genes to human (15q15.1) and mouse (2F1) chromosomes by direct R-banding fluorescence in situ hybridization. Genomics 1994; 19: 376–378
   PubMed Web of Science ®Google Scholar
• Thompson L.H., Suit H.D. Proliferation kinetics of x-irradiated mouse L cells studied with time-lapse photography. International Journal of Radiation Biology 1969; 15: 347–362
   Web of Science ®Google Scholar
• Todd P. Defective mammalian cells isolated from X-irradiated cultures. Mutation Research 1968; 5: 173–183
   PubMed Web of Science ®Google Scholar
• Vaux D.L., Cory S., Adams J.M. Bel-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 1988; 335: 440–442
   PubMed Web of Science ®Google Scholar
• Westra A., Barendsen G.W. Proliferation characteristics of cultured mammalian cells after irradiation with sparsely and densely ionizing radiations. International Journal of Radiation Biology 1966; 11: 477–485
   Web of Science ®Google Scholar
• Yandell D.W., Dryja T.P., Little J.B. Molecular genetic analysis of recessive mutations at a heterozygous autosomal locus in human cells. Mutation Research 1990; 229: 89–102
   PubMedGoogle Scholar
• Yin Y., Tainsky M.A., Bischoff F.Z., Strong L.C., Wahl G.M. Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell 1992; 70: 937–948
   PubMed Web of Science ®Google Scholar