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International Journal of Radiation Biology Volume 67, 1995 - Issue 2
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Original Article

Bis-dithiocarbamates: Effective Chelating Agents for Mobilization of Polonium-210 from Rat

J. Rencová National Institute of Public Health, Centre of Radiation Hygiene, Šrobárova 48, 100 42, Praha, Czech Republic
,
V. Volf Department of Chemistry and Center in Molecular Toxicology, Vanderbilt University, PO Box 1583, Nashville, TN, 37235, USA
,
M.M. Jones National Institute of Public Health, Centre of Radiation Hygiene, Šrobárova 48, 100 42, Praha, Czech Republic
,
P.K. Singh Department of Chemistry and Center in Molecular Toxicology, Vanderbilt University, PO Box 1583, Nashville, TN, 37235, USA
&
R. Filgas National Institute of Public Health, Centre of Radiation Hygiene, Šrobárova 48, 100 42, Praha, Czech Republic
Pages 229-234 | Received 29 Apr 1994, Accepted 31 Aug 1994, Published online: 03 Jul 2009

References

  • Aposhian H.V., Bruce D. Binding of polonium-210 to liver metallothionein. Radiation Research 1991; 126: 379–382
  • Aposhian H.V., Dart R.C., Aposhian M.M., Dawson B.V. Tissue decorporation of polonium-210 in rats by DMPA. Research Communications in Chemical Pathology and Pharmacology 1987; 58: 157–171
  • Bogdan G.M., Aposhian H.V. N-(2,3-dimercaptopropyl)-phtalamidic acid (DMPA) increases polonium-210 excretion. Biology of Metals 1990; 3: 232–236
  • Fink R.M. Biological Studies with Polonium, Radium and Plutonium. McGraw-Hill, New York 1950
  • Moroz B.B., Parfenov Yu.D. Effect of Polonium-210 on the Organism. Atomizdat, Moscow 1971, [in Russian]
  • Rencová J., Volf V., Jones M.M., Singh P.K. Relative effectiveness of dithiol and dithiocarbamate chelating agents in reducing retention of polonium-210 in rats. International Journal of Radiation Biology 1993; 63: 223–232
  • Rencová J., Volf V., Jones M.M., Singh P.K. Decorporation of polonium from rats by new chelating agents. Radiation Protection Dosimetry 1994; 53: 311–313
  • Seidel A. Metabolism and toxicology of polonium and its removal from the body. Polonium, Gmelin Handbook of Inorganic and Organometallic Chemistry, K.-C. Buschbeck, C. Keller. Springer, Berlin 1990; 251–274, In Suppl. 1
  • Seidel A., Volf V. Rapid determination of some transuranium elements in biological material by liquid scintillation counting. International Journal of Applied Radiation and Isotopes 1972; 23: 1–4
  • Singh P.K., Jones M.M., Jones S.G., Gale G.R., Atkins L.M., Smith A.B., Bullman R.A. Effect of chelating agent structure on the mobilization of cadmium from intracellular deposits. Journal of Toxicology and Environmental Health 1989; 28: 501–518
  • Volf V. Dekorporierung von Radionukliden (Untersuchungen an Polonium). Strahlentherapie 1973; 145: 101–115

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