Mechanisms of Radiosensitization in Iododeoxyuridine-Substituted Cells

References

• Blakely W.F., Ward J.F., Joner E.I. A quantitative assay of deoxyribonucleic acid strand breaks and their repair in mammalian cells. Analytical Biochemistry 1982; 124: 125–133
   PubMed Web of Science ®Google Scholar
• Bradley M.O., Kohn K.W. X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral elution. Nucleic Acids Research 1979; 7: 793–804
   PubMed Web of Science ®Google Scholar
• Buxton G.V., Greenstock C.L., Helman W.P., Ross A.B. Critical review of rate constants for reactions of hydrated electrons, hydrogen atoms and hydroxyl radicals (·OH/·O-). Journal of Physical Chemical Reference Data 1988; 17: 513–886
   Web of Science ®Google Scholar
• Erikson R.L., Szybalski W. Molecular radiobiology of human cell lines. V. Comparative radiosensitizing properties of 5-halodeoxycytidines and 5-halodeoxyuridines. Radiation Research 1963; 20: 253–262
   Web of Science ®Google Scholar
• Iliakis G., Kurtzman S. Mechanism of radiosensitization by halogenated pyrimidines: BrdU and β-arabinofura-nosyladenine affect similar subsets of radiation induced potentially lethal damage in plateau-phase Chinese hamster ovary cells. Radiation Research 1991; 127: 45–51
   PubMed Web of Science ®Google Scholar
• Iliakis G., Kurtzman S., Pantelias G., Okayasu R. Mechanism of radiosensitization by halogenated pyrimidines: effect of BrdU on radiation induction of DNA and chromosome damage and its correlation with cell killing. Radiation Research 1989; 119: 286–304
   PubMed Web of Science ®Google Scholar
• Iliakis G., Pantelias G., Kurtzman S. Mechanism of radiosensitization by halogenated pyrimidines: effect of BrdU on cell killing and interphase chromosome breakage in radiation-sensitive cells. Radiation Research 1991; 125: 56–64
   PubMed Web of Science ®Google Scholar
• Iliakis G., Wang Y., Pantelias G., Metzger L. Mechanism of radiosensitization by halogenated pyrimidines: effect of BrdU on repair of DNA breaks, interphase chromatin breaks, and potentially lethal damage in plateau-phase CHO cells. Radiation Research 1992; 129: 202–211
   PubMed Web of Science ®Google Scholar
• Iliakis G., Wright E., Ngo F.Q.H. Possible importance of PLD repair in the modulation of BrdUrd and IdUrd-mediated radiosensitization in plateau-phase C3H10T1/2 mouse embryo cells. International Journal of Radiation Biology 1987a; 51: 541–548
   Web of Science ®Google Scholar
• Iliakis G., Wright E., Ngo F.Q.H. Repair and fixation of potentially lethal damage (PLD) as demonstrated by delayed plating or incubation with araA in contact inhibited plateau-phase C3H mouse embryo 10T1/2 cells grown in the presence of BrdUrd. Radiation and Environmental Biophysics 1987b; 26: 47–62
   PubMed Web of Science ®Google Scholar
• Johansen I., Howard-Flanders P. Macromolecular repair and free radical scavenging in the radiation protection of bacteria against X-rays. Radiation Research 1965; 24: 184–200
   PubMed Web of Science ®Google Scholar
• Kinsella T.J., Dobson P.P., Mitchell J.B., Fornace A.J. Enhancement of x-ray induced DNA damage by pre-treatment with halogenated pyrimidine analogs. International Journal of Radiation Oncology, Biology and Physics 1987; 13: 733–739
   PubMed Web of Science ®Google Scholar
• Kinsella T.J., Glastein E. Clinical experience with intravenous radiosensitizers in unresectable sarcomas. Cancer 1987; 59: 908–915
   PubMed Web of Science ®Google Scholar
• Kinsella T.J., Russo A., Mitchell J.B., Collins J.R., Rowland J., Wright D., Glastein E. Phase I study of intravenous iododeoxyuridine as a clinical radiosensitizer. International Journal of Radiation Oncology, Biology and Physics 1985; 11: 1941–1946
   PubMed Web of Science ®Google Scholar
• Lawrence T.S., Davis M.A., Maybaum J., Mukhopadhyay S.K., Stetson P.L., Normolle D.P., McKeever P.E., Ensminger W.D. The potential superiority of bromodeoxyuridine to iododeoxyuridine as a radiation sensitizer in the treatment of colorectal cancer. Cancer Research 1992; 52: 3698–3704
   PubMed Web of Science ®Google Scholar
• Limoli C.L., Ward J.F. A new method for introducing double-strand breaks into cellular DNA. Radiation Research 1993; 134: 160–169
   PubMed Web of Science ®Google Scholar
• Ling L.L., Ward J.F. Radiosensitization of Chinese hamster V79 cells by bromodeoxyuridine substitution of thymidine: enhancement of radiation-induced toxicity and DNA strand break, production by monofilar and bifilar substitution. Radiation Research 1990; 121: 76–83
   PubMed Web of Science ®Google Scholar
• Mitchell J.B., Morstyn G., Russo A., Kinsella T.J., Fornace A., McPherson S., Glastein E. Differing sensitivity to fluorescent light in Chinese hamster cells containing equally incorporated quantities of BudR versus IUdR. International Journal of Radiation Oncology, Biology and Physics 1984; 10: 1447–1551
   PubMed Web of Science ®Google Scholar
• Speth P.A., Kinsella T.J., Chang A.E., Klecker R.W., Belanger K., Smith R., Rowland J., Cupp J.E., Collins J.M. Iododeoxyuridine (IdUrd) incorporation into DNA of human haematopoietic cells, normal liver and hepatic metastases in man: as a radiosensitizer and as a marker for cell kinetic studies. International Journal of Radiation Oncology, Biology and Physics 1989; 16: 1247–1250
   PubMed Web of Science ®Google Scholar
• Wang Y., Iliakis G. Effects of 5-iododeoxyuridine on the repair of radiation induced potentially lethal damage interphase chromatin breaks and DNA double strand breaks in Chinese hamster ovary cells. International Journal of Radiation Oncology, Biology and Physics 1992; 23: 353–360
   PubMed Web of Science ®Google Scholar
• Ward J.F. Some biochemical consequences of the spatial distribution of ionizing radiation-produced free radicals. Radiation Research 1981; 86: 185–195
   PubMed Web of Science ®Google Scholar
• Ward J.F. Biochemistry of DNA lesions. Radiation Research 1985; 104: S103–111
   Web of Science ®Google Scholar
• Ward J.F. DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation and repairability. Progress in Nucleic Acids and Molecular Biology 1988; 35: 95–125
   PubMed Web of Science ®Google Scholar
• Webb C.F., Jones G.D.D., Ward J.F., Moyer D.J., Aguilera J.A. Mechanisms of radiosensitization in bromodeoxyuridine-substituted cells. International Journal of Radiation Biology 1993; 64: 695–705
   PubMed Web of Science ®Google Scholar