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International Journal of Radiation Biology Volume 70, 1996 - Issue 6
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Research Article

Chelation therapy by DFO-HOPO and 3,4,3-LIHOPO for injected Pu-238 and Am-241 in the rat: effect of dosage, time and mode of chelate administration

V. VOLF Forschungszentrum Karlsruhe: Technik und Umwelt, Institut fur Toxikologie, Postfach 3640, 76021 Karlsruhe, Germany. Laboratorie de Chimie des Organo-elements, Universite Pierre et Marie Curie, F-75252 Paris, France. Department of Chemistry and Lawrence Berkeley Laboratory, University of California, Berkeley, CA 94720, USA.
Pages 765-772 | Published online: 03 Jul 2009

References

  • BREITENSTEIN, B. D. and PALMER, H. E., 1989, Life time follow up of the 1976 American accident victim. Radiation Protec-tion Dosimetry, 26, 317–322.
  • DURBIN, P. W., JEUNG, N., RODGERS, S. J., TUROWSKI, P. N., WEITL, F. L., WHITE, D. L. and RAYMOND, K. N., 1989a, Removal of Pu-238(IV) from mice by polycatecholate, - hydroxamate, or -hydroxypyridonate ligands. Radiation Protection Dosimetry, 26, 351–358.
  • DURBIN, P. W., JONES, E. S., RAYMOND, K. N. and WEITL, F. L., 1980, Specific sequestring agents for the actinides. 4. Removal of Pu (IV) from mice by sulfonated tetrameric catechoyl amides. Radiation Research, 81, 170–187.
  • DURBIN, P. W., WHITE, D. L., JEUNG, N., WEITL, F. L., UHLIR, L. C., JONES, S. E., BRUENGER, F. W. and RAYMOND, K. N., 1989b, Specific sequestring agents for the actinides. 18. In-vivo chelation of Pu-238(IV) by 3,4,3-LICAM(C): effects of ligand methylation and pH. Health Physics, 56, 839–855.
  • GRAY, S. A., PEARCE, M. J., STRADLING, G. N., WILSON, I., HODGSON, A. and IsAAcs, K. R., 1995, Optimizing removal of inhaled plutonium and americium from the rat by administration of ZnDTPA in drinking water. Human and Experimental Toxicology, 14, 902–908.
  • PAQUET, F., PONCY, J. L., RATEAU, G., BURGADA, R., BAILLY, T., LEROUX, y, RAYMOND, K. N., DURBIN, P. W. and MASSE, R., 1994, Reduction of the retention of 238Pu inhaled as the tributylphosphate complex in rats treated by 3,4,3-LIHOP0. Radiation Protection Dosimetry, 53, 323–326.
  • PONCY, J. L., RATEAU, G., BURGADA, R., BAILLY, T., LEROUX, Y, RAYMOND, K. N., DURBIN, P. W. and MASSE, R., 1993, Effi-cacy of 3,4,3-LIHOPO for reducing the retention of 238 Pu Pu n rat after inhalation of the tributyl phosphate complex. International Journal of Radiation Biology, 64, 431–436.
  • SEIDEL, A. and VOLE, V., 1972, Rapid determination of some transuranium elements in biological material by liquid scintillation counting. International Journal of Applied Radiation and Isotopes, 23, 1–4.
  • STRADLING, G. N., STATHER, J. W., GRAY, S. A., MOODY, J. C., ELLENDER, M., HODGSON, A., VOLE, V., TAYLOR, D. M., WIRTH, P. and GASKIN, P. W., 1989, The efficacies of pure LICAM (C) and DTPA on the retention of plutonium-238 and americium-241 in rats after their inhalation as nitrate and intravenous injection as citrate. Interna-tional Journal of Radiation Biology, 56, 503–514.
  • STRADLING, G. N., GRAY, S. A., MOODY, J. C., HODGSON, A., RAYMOND, K. N., DURBIN, P. W., RODGERS, S. J., WHITE, D. L. and TUROWSKI, P. N., 1991, The efficacy of DFO-HOPO, DTPA-DX and DTPA for enhancing the excretion of plutonium and americium from the rat. International Journal of Radiation Biology, 59, 1269–1277.
  • STRADLING, G. N., GRAY, S. A., ELLENDER, M., MOODY, J. C., HODGSON, A., PEARCE, M., WILSON, I., BURGADA, R., BAILLY, T., LEROUX, y, EL MANOUNI, D., RAYMOND, K. N. and DURBIN, P. W., 1992, The efficacies of 3,4,3-LIHOPO and DTPA for enhancing the excretion of plutonium and americium from the rat: comparison with other siderophore analogues. InternationalJournal of Radiation Biology, 62, 487–497.
  • VOLL, V., 1978, Treatment of Incorporated Transuranium Elements. Technical Reports Series No 184 (Vienna: Interna-tional Atomic Energy Agency).
  • VOLK, V., 1986, Chelation therapy of incorporated plutonium-238 and americium-241: comparison of LICAM(C), DTPA and DFOA in rats, hamsters and mice. Inter-national Journal of Radiation Biology, 49, 331–335.
  • VOLE, V., 1989, Optimisation and status of chelation therapy. Radiation Protection Dosimetry, 26, 331–335.
  • VOLL, V., BURGADA, R., RAYMOND, K. N. and DURBIN, P.W., 1993, Early chelation therapy for injected Pu-238 and Am-241 in the rat: comparison of 3,4,3-LIHOPO, DFO-HOPO, DTPA-DX, DTPA and DFOA. International Journal of Radiation Biology, 63, 785–793.

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