- ANDERSON, C. W. and LEES-MILLER, S. P., 1992, The nuclear serine/threonine protein kinase DNA-PK. Critical Renews in Eukaryotic Gene Expression, 2, 283-314.
- ARAKI, R., FUJIMORI, A., HAMATANI, K., MITA, K., SAITO, T., MORI, M., FUKUMURA, R., MORIMYO, M., MUTO, M., ITOH, M. and TATSUMI, K., 1997, Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice. Proceedings of the National Academy of Sciences, USA, 94, 2438-2443.
- BLUNT, T., FINNIE, N. J., TACCIOLI, G. E., SMITH, G. C. M., DEMENGEOT, J., GOTTLIEB, T. M., MIZUTA, R., VARGHESE, A. J., ALT, F. W., JEGGO, P. A. and JACKSON, S. P., 1995, Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine seid mutation. Cell, 80, 813-823.
- BOSMA, G. C., CUSTER, R. P. and BOSMA, M. J., 1983, A severe combined immunodeficiency mutation in the mouse. Nature, 301, 527-530.
- BOUBNOV, N. V., HALL, K. T., WILLS, Z., LEE, S. E., HE, D. M., BENJAMIN, D. M., PULASKI, C. R., BAND, H., REEVES, W., HENDRICKSON, E. A. and WEAVER, D. T., 1995, Complementation of the ionizing radiation sensitivity, DNA end binding, and V(D)J recombination defects of double-strand break repair mutants by the p86 Ku autoantigen. Proceedings of the National Academy of Sciences, USA, 92, 890-894.
- BURGMAN, P., OUYANG, H., PETERSON, S., CHEN, D. J. and LI, G. C., 1997, Heat inactivation of Ku autoantigen: possible role in hyperthermic radiosensitization. Cancer Research, 57, 2847-2850.
- FINNIE, N. J., GOTTLIEB, T. M., BLUNT, T., JEGGO, P. A. and JACKSON, S. P., 1995, DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for sitespecific recombination and DNA double-strand break repair. Proceedings of the National Academy of Sciences, USA, 92, 320-324.
- FULOP, G. M. and PHILLIPS, R. A., 1990, The seid mutation in mice causes a general defect in DNA repair. Nature, 347, 479-482.
- HE, D. M., LEE, S. E. and HENDRICKSON, E. A., 1996, Restoration of X-ray and etoposide resistance, Ku-end binding activity and V(D)J recombination to the Chinese hamster sxi-3 mutant by a hamster Ku86 cDNA. Mutation Research, 366, 43-56.
- ILIAKIS, G. and SEANER, R., 1990, A DNA double-strand break repair-deficient mutant of CHO cells shows reduced radiosensitization after exposure to hyperthermic temperatures in the plateau phase of growth. International Journal of Hypertherma, 6, 801-812.
- KHARBANDA, S., PANDEY, P., JIN, S., INOUE, S., BHARTI, A., YUAN, Z.-M., WEICHSELBAUM, R., WEAVER, D. and KUFE, D., 1997, Functional interaction between DNA-PK and c-Abl in response to DNA damage. Nature, 386, 732-735.
- KIM, D., OUYANG, H., YANG, S.-H., NUSSENZWEIG, A., BURGMAN, P. and LI, G. C., 1995, A constitutive heat shock element-binding factor is immunologically identical to the Ku autoantigen. Journal of Biological Chemistry, 270, 15277-15284.
- KIRCHGESSNER, C. U., PATIL, C. K., EVANS, J. W., CUOMO, C. A., FRIED, L. M., CARTER, T., OETTINGER, M. A. and BROWN, J. M., 1995, DNA-dependent kinase (p350) as a candidate gene for the murine seid defect. Science, 267, 1178-1183.
- KOMATSU, K., KUBOTA, N., GALLO, M., OKUMURA, Y. and LIEBER, M. L., 1995, The seid factor on human chromosome 8 restores V(D)J recombination in addition to double-strand break repair. Camer Research, 55, 1774-1779.
- KOMATSU, K., OHTA, T., JINNNO, Y., NIIKAWA, N. and OKUMURA, Y., 1993, Functional complementation in mouse-human radiation hybrids assigns the putative murine seid gene to the pericentric region of human chromosome 8. Human Molecular Genetics, 2, 1031-1034.
- LEE, S. E., PULASKI, C. R., HE, D. M., BENJAMIN, D. M, Voss, M., UM, J. and HENDRICKSON, E. A., 1995, Isolation of mammalian cell mutants that are X-ray sensitive, impaired in DNA double-strand break repair and defective for V(D)J recombination. Mutation Research, 336, 279-291.
- LIU, R. Y., KIM, D., YANG, S. H. and LI, G. C., 1993, Dual control of heat shock response: involvement of a constitutive heat shock element-binding factor. Proceedings of the National Academy of Sciences, USA, 90, 3078-3082.
- MATSUMOTO, Y., SUZUKI, N., SAKAI, K., MORIMATSU, A., HIRANO, K. and MUROFUSHI, H., 1997, A possible mechanism for hyperthermic radiosensitization mediated through hyperthermic lability of Ku subunits in DNAdependent protein kinase. Biochemical and Biophysical Research Communications, 234, 568-572.
- MIMORI, T., HARDIN, J. A. and STEITZ, J. A., 1986, Characterization of the DNA-binding protein antigen Ku recognized by autoantibodies from patients with rheumatic disorders. Journal of Biological Chemistry, 261, 2274-2278.
- NEVALDINE, B, LONGO, J. A. and HAHN, P. J., 1994, Hyperthermia inhibits the repair of DNA double-strand breaks induced by ionizing radiation as determined by pulsed-field gel electrophoresis. International Journal of Hyperthermia, 10, 381-388.
- RATHMELL, W. K. and CHU, G., 1994, Involvement of the Ku autoantigen in the cellular response to DNA doublestrand breaks. Proceedings of the National Academy of Sciences, U S A, 91, 7623-7627.
- SATOH, M., WANG, J. and REEVES, W. H., 1995, Role of free p70 (Ku) subunit in posttranslational stabilization of newly synthesized p80 during DNA-dependent protein kinase assembly. European Journal of Cell Biology, 66, 127-135.
- SMIDER, V., RATHMELL, W. K., LIEBER, M. R. and CHU, G., 1994, Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA. Science, 266, 288-291.
- SUWA, A., HIRAKATA, M., TAKEDA, Y., JESCH, S. A., MIMORI, T. and HARDIN, J. A., 1994, DNA-dependent protein kinase (Ku protein-p350 complex) assembles on double-stranded DNA. Proceedings of the National Academy of Sciences, USA, 91, 6904-6908.
- SUWA, A., HIRAKATA, M., TAKEDA, Y., OKANO, Y., MIMORI, T., INADA, S., WATANABE, F., TERAOKA, H., DYNAN, W. S. and HARDIN, J. A., 1996, Autoantibodies to DNA-dependent protein kinase. Probes for the catalytic subunit. Journal of Clinical Investigation, 97, 1417-1421.
Heat sensitivity of double-stranded DNA-dependent protein kinase (DNA-PK) activity
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.