Publication Cover
Physiotherapy Theory and Practice
An International Journal of Physical Therapy
Volume 35, 2019 - Issue 5
286
Views
4
CrossRef citations to date
0
Altmetric
Single Subject Research Report

Safety and feasibility of transcranial direct current stimulation in amyotrophic lateral sclerosis – a pilot study with a single subject experimental design

ORCID Icon, , &
Pages 458-463 | Received 15 May 2017, Accepted 29 Aug 2017, Published online: 28 Feb 2018

References

  • Angelucci F, Oliviero A, Pilato F, Saturno E, Dileone M, Versace V, Musumeci G, Batocchi AP, Tonali PA, Di Lazzaro V 2004 Transcranial magnetic stimulation and BDNF plasma levels in amyotrophic lateral sclerosis. Neuroreport 15: 717–720.
  • Attarian S, Vedel JP, Pouget J, Schmied A 2006 Cortical versus spinal dysfunction in amyotrophic lateral sclerosis. Muscle and Nerve 33: 677–690.
  • Attarian S, Vedel JP, Pouget J, Schmied A 2008 Progression of cortical and spinal dysfunctions over time in amyotrophic lateral sclerosis. Muscle and Nerve 37: 364–375.
  • Benninger DH, Lomarev M, Lopez G, Wassermann EM, Li X, Considine E, Hallett M 2010 Transcranial direct current stimulation for the treatment of Parkinson’s disease. Journal of Neurology, Neurosurgery and Psychiatry 81: 1105–1111.
  • Boillée S, Velde CV, Cleveland DW 2006 ALS: A disease of motor neurons and their nonneuronal neighbors. Neuron 52: 39–59.
  • Boros K, Poreisz C, Münchau A, Paulus W, Nitsche MA 2008 Premotor transcranial direct current stimulation (tDCS) affects primary motor excitability in humans. European Journal of Neuroscience 27: 1292–1300.
  • Dawbarn D, Allen S 2003 Neurotrophins and neurodegeneration. Neuropathology and Applied Neurobiology 29: 211–230.
  • Di Lazzaro V, Dileone M, Pilato F, Profice P, Ranieri F, Musumeci G, Angelucci F, Sabatelli M, Tonali PA 2006 Repetitive transcranial magnetic stimulation for ALS. A preliminary controlled study. Neuroscience Letters 408: 135–140.
  • Di Lazzaro V, Ranieri F, Capone F, Musumeci G, Dileone M 2013 Direct current motor cortex stimulation for amyotrophic lateral sclerosis: A proof of principle study. Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation 6: 969–970.
  • Flöel A 2014 tDCS-enhanced motor and cognitive function in neurological diseases. Neuroimage 85: 934–947.
  • Floyd A, Yu Q, Piboolnurak P, Tang M, Fang Y, Smith W, Yim J, Rowland L, Mitsumoto H, Pullman S 2009 Transcranial magnetic stimulation in ALS Utility of central motor conduction tests. Neurology 72: 498–504.
  • Goldfarb B, Simon S 1984 Gait patterns in patients with amyotrophic lateral sclerosis. Archives of Physical Medicine and Rehabilitation 65: 61–65.
  • Hausdorff JM, Lertratanakul A, Cudkowicz ME, Peterson AL, Kaliton D, Goldberger AL 2000 Dynamic markers of altered gait rhythm in amyotrophic lateral sclerosis. Journal of Applied Physiology 88: 2045–2053.
  • Iyer M, Mattu U, Grafman J, Lomarev M, Sato S, Wassermann E 2005 Safety and cognitive effect of frontal DC brain polarization in healthy individuals. Neurology 64: 872–875.
  • Kendall FP, McCreary EK, Provance PG, Rodgers MM, Romani WA 1993 Muscles, Testing and Function, with Posture and Pain, 4th. Lippincott Williams and Wilkins, Philadelphia, USA.
  • Khedr E, Ahmed M, Hamdy A, Shawky O 2011 Cortical excitability of amyotrophic lateral sclerosis: Transcranial magnetic stimulation study. Clinical Neurophysiology 41: 73–79.
  • Konrad C, Jansen A, Henningsen H, Sommer J, Turski P, Brooks B, Knecht S 2006 Subcortical reorganization in amyotrophic lateral sclerosis. Experimental Brain Research 172: 361–369.
  • Madhavan S, Shah B 2012 Enhancing motor skill learning with transcranial direct current stimulation–A concise review with applications to stroke. Frontiers in Psychiatry 3: 66.
  • Menon P, Kiernan MC, Vucic S 2015 Cortical hyperexcitability precedes lower motor neuron dysfunction in ALS. Clinical Neurophysiology 126: 803–809.
  • Munneke MA, Stegeman DF, Hengeveld YA, Rongen JJ, Schelhaas HJ, Zwarts MJ 2011 Transcranial direct current stimulation does not modulate motor cortex excitability in patients with amyotrophic lateral sclerosis. Muscle and Nerve 44: 109–114.
  • Musselman KE 2007 Clinical significance testing in rehabilitation research: What, why, and how? Physical Therapy Reviews 12: 287–296.
  • Nitsche MA, Liebetanz D, Lang N, Antal A, Tergau F, Paulus W 2003 Safety criteria for transcranial direct current stimulation (tDCS) in humans. Clinical Neurophysiology 114: 2220–2223.
  • Podda MV, Cocco S, Mastrodonato A, Fusco S, Leone L, Barbati SA, Colussi C, Ripoli C, Grassi C 2016 Anodal transcranial direct current stimulation boosts synaptic plasticity and memory in mice via epigenetic regulation of Bdnf expression. Scientific Reports 6: 22180.
  • Polanía R, Paulus W, Nitsche MA 2012a Modulating cortico‐striatal and thalamo‐cortical functional connectivity with transcranial direct current stimulation. Human Brain Mapping 33: 2499–2508.
  • Polanía R, Paulus W, Nitsche MA 2012b Reorganizing the intrinsic functional architecture of the human primary motor cortex during rest with non-invasive cortical stimulation. PloS One 7: e30971.
  • Poreisz C, Boros K, Antal A, Paulus W 2007 Safety aspects of transcranial direct current stimulation concerning healthy subjects and patients. Brain Research Bulletin 72: 208–214.
  • Purpura DP, McMurtry JG 1965 Intracellular activities and evoked potential changes during polarization of motor cortex. Journal of Neurophysiology 28: 166–185.
  • Quartarone A, Lang N, Rizzo V, Bagnato S, Morgante F, Sant’Angelo A, Crupi D, Battaglia F, Messina C, Girlanda P 2007 Motor cortex abnormalities in amyotrophic lateral sclerosis with transcranial direct‐current stimulation. Muscle and Nerve 35: 620–624.
  • Rothstein JD, Van Kammen M, Levey AI, Martin LJ, Kuncl RW 1995 Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis. Annals of Neurology 38: 73–84.
  • Sivaramakrishnan A, Tahara-Eckl L, Madhavan S 2016 Spatial localization and distribution of the TMS-related ‘hotspot’of the tibialis anterior muscle representation in the healthy and post-stroke motor cortex. Neuroscience Letters 627: 30–35.
  • Tilson JK, Sullivan KJ, Cen SY, Rose DK, Koradia CH, Azen SP, Duncan PW, Team LEAPSI 2010 Meaningful gait speed improvement during the first 60 days poststroke: Minimal clinically important difference. Physical Therapy 90: 196–208.
  • Vucic S, Nicholson GA, Kiernan MC 2008 Cortical hyperexcitability may precede the onset of familial amyotrophic lateral sclerosis. Brain 131: 1540–1550.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.