66
Views
15
CrossRef citations to date
0
Altmetric
Research Article

The health effects of ecstasy: a literature review

, , &
Pages 53-63 | Published online: 12 Jul 2009

  • Wolff K, Hay AW, Sherlock K & Conner M. Contents of "ecstasy". Lancet 1995;346:1100-1.
  • Anonymous. Ecstasy. NIDA Infofax. National Institute on Drug Abuse, 1999. Available from: http:www.nida.nih.gov/ Infofax/ecstasy.html
  • European Monitoring Centre for Drugs and Drug Addiction. Annual report on the state of the drugs problem in the European Union. Luxembourg: Office for Official Publications of the European Communities, 1999.
  • Topp L, Hando J, Degenhardt L, Dillon P, Roche A, Solowij N. Ecstasy use in Australia. NDARC monograph no. 39. Sydney, Australia: National Drug and Alcohol Research Centre, 1997.
  • McKetin R, Darke S, Hayes A, Rumbold G. Drug Trends 1998. A comparison of drug use and trends in three Australian States: findings from the Illicit Drug Reporting System (IDRS). NDARC monograph no. 41. Sydney, Australia: National Drug and Alcohol Research Centre, 1999.
  • Sherlock K, Conner M. Patterns of ecstasy use amongst club-goers on the UK "dance scene". Int J Drug Policy 1999;10:117-29.
  • Humeniuk R. South Australian Drug Trends 1999. Findings from the Illicit Drug Reporting System. NDARC technical report no. 88. Sydney, Australia: National Drug and Alcohol Research Centre, 2000.
  • Handy C, Pates R, Barrowcliff A. Drug use in South Wales: who uses Ecstasy anyway? J Suhst Misuse 1998;3:82-8.
  • Schifano F. Potential human neurotoxicity of MDMA ("Ecstasy"): subjective self-reports, evidence from an Italian drug addiction centre and clinical case studies. Neuropsychobiology 2000;42:25-33.
  • Schuster P, Lieb R, Lamertz C, Wittchen HU. Is the use of ecstasy and hallucinogens increasing? Results from a community study. Eur Addict Res 1998;4:75-82.
  • Topp L, HaIlW, Hando J. Is there a dependence syndrome for ecstasy? NDARC technical report no. 51. Sydney, Australia: National Drug and Alcohol Research Centre, 1997.
  • JansenKL. Ecstasy (MDMA) dependence. Drug Alcohol Depend 1999;53:121-4.
  • Battaglia G, De Souza EB. Pharmacologie profile of amphetamine derivatives at various brain recognition sites: selective effects on serotonergic systems. NIDA Res Monogr 1989;94:240-58.
  • Pierce PA, Peroutka SJ. Ring-substituted amphetamine interactions with neurotransminer receptor binding sites in human cortex. Neurosci Lett 1988;95:208-12.
  • Schloss P, Williams DC. The serotonin transporter: a primary target for antidepressant drugs. J Psychopharmacol 1998;12:115-21.
  • Rawson RA. Treatment for stimulant use disorders. Treatment improvement protocol (TIP) series no. 33. Rockville, Maryland: US Department of Health and Human Services, 1999.
  • Daws L, Irvine RJ, Callaghan PD, Toop PN, White JM, Bochner F. Differential behavioural and neurochemical effects of para-methoxyamphetamine and 3,4-methylenedioxymethamphetamine in the rat. Prog Neuropsychopharmacol Biol Psychiatry 2000;24:955-77.
  • Malberg JE, Seiden LS. Small changes in ambient temperature cause large changes in 3,4-methylenedioxymethamphetamine (MDMA)-induced serotonin neurotoxicity and core body temperature in the rat. J Neurosci 1998;18:5086-94.
  • Sternbach H. The serotonin syndrome. Am J Psychiatry 1991;148:705-13.
  • Loscher W, Witte U, Fredow G, Ganter M, Bickhardt K. Pharmacodynamic effects of serotonin (5-HT) receptor ligands in pigs: stimulation of 5-HT2 receptors induces malignant hyperthermia. Naunyn-Schmeideberg's Arch Pharmacol 1990;341:483-93.
  • Cohen RS. Subjective reports on the effects of the MDMA (Ecstasy) experience in humans. Prog Neuropsychopharmacol Biol Psychiatry 1995;19:1137-45.
  • Peroutka SJ, Newman H, Harris H. Subjective effects of 3,4-methylenedioxymethamphetamine in recreational users. Neuropsychopharmacology 1988;l:273-7.
  • Vollenweider FX, Gamma A, Liechti M, Huber T. Psychological and cardiovascular effects and short-term sequelae of MDMA (ecstasy) in MDMA-naive healthy volunteers. Neuropsychopharmacology 1998;19:241-51.
  • Peroutka SJ. Recreational use of MDMA. Peroutka SJ, ed. In: Ecstasy: the clinical, pharmacological and neurotoxicological effects of the drug MDMA. Boston: Kluwer Academic Publishers, 1990:53-62.
  • Siegel RK. MDMA: nonmedical use and intoxication. J Psychoact Drugs 1986;18:349-54.
  • Mas M, FarreM, de lalbrre R, et al. Cardiovascular and neuroendocrine effects and pharmacokinetics of 3,4-methylenedioxymethamphetamine in humans. J Pharmacol Exp Ther 1999;290:136-45.
  • Verebey K. The complications of "ecstasy" (MDMA). JAMA 1988;259:1649-50.
  • de la Torre R, Farre M, Ortuno J, et al. Non-linear pharmacokinetics of MDMA ("ecstasy") in humans. Br J Clin Pharmacol 2000;49:104-9.
  • Tucker GT, Lennard MS, Ellis SW, et al. The demethylenation of methylenedioxymethamphetamine (ecstasy) by debrisoquine hydroxylase (CYP2D6). Biochem Pharmacol 1994;47:1151-6.
  • O'Donohoe A, O'Flynn K, Shields K, Hawi Z, Gill M. MDMA toxicity: no evidence for a major influence of metabolic genotype at CYP2D6. Addict Biol 1998;3: 309-14.
  • Schwab M, Seyringer E, Brauer RB, Hellinger A, Griese EU. Fatal MDMA intoxication. Lancet 1999;353: 593-4.
  • Kreth K, Kovar K, Schwab M, Zanger UM. Identification of the human cytochromes P450 involved in the oxidative metabolism of ecstasy-related designer drugs. Biochem Pharmacol 2000;59:1563-71.
  • Coore JR. A fatal trip with ecstasy: a case of 3,4-methylenedioxymethamphetamine/3,4-methylenedioxyamphetamine toxicity. J Roy Soc Med 1996;89:51P-52P.
  • Bingham C, Beaman M, Nicholls AJ, Anthony PP. Necrotizing renal vasculopathy resulting in chronic renal failure after ingestion of methamphetamine and 3,4-methylenedioxyrnetharnphetarnine ("ecstasy"). Nephrol Dial Transplant 1998:13:2654-5.
  • Henry JA, Hill IR. Fatal interaction between ritonavir and MDMA. Lancet 1998;352:1751-2.
  • McCann UD, Eligulashvili V, Ricaurte GA. ( +/-)3,4-Methylenedioxymethamphetanune ("Ecstasy")-induced serotonin neurotoxicity: clinical studies. Neuropsychobiology 2000;42:11-16.
  • Hatzidimitriou G, McCann UD, Ricaurte GA. Altered serotonin innervation patterns in the forebrain of monkeys treated with (+/-)3,4-methylenedioxymethamphetamine seven years previously: factors influencing abnormal recovery. J Neurosci 1999;19:5096-107.
  • Boot BP, McGregor IS, Hall W. MDMA (Ecstasy) neurotoxicity: assessing and communicating the risks. Lancet 2000;355:1818-21.
  • McCann UD, Szabo Z, Scheffel U, Dannals RF, Ricaurte GA. Positron emission Homographie evidence of toxic effect of MDMA (ecstasy) on brain serotonin neurons in human beings. Lancet 1998;352:1433-7.
  • Semple DM Ebmeier KP, Glabus MF, O'Carroll RE, Johnstone EC. Reduced in vivo binding to the serotonin transporter in the cerebral cortex of MDMA ("ecstasy") users. Br J Psychiatry 1999;175:63-9.
  • Obrocki J, Buchert R, Vaterlein O, Thomasius R, Beyer W, Schiemann T. Ecstasy-long-term effects on the human central nervous system revealed by positron emission tomography. Br J Psychiatry 1999;175:186-8.
  • Chang L, Ernst T, Grob CS, Poland RE. Cerebral (1)H MRS alterations in recreational 3, 4-methylenedioxyme-thamphetamine (MDMA, ecstasy) users. J Magn Reson Imaging 1999;10:521-6.
  • Chang L, Grob CS, Ernst T, et al. Effect of ecstasy [3,4-methylenedioxymethamphetamine (MDMA)] on cerebral blood flow: a co-registered SPECT and MRI study. Psycbiatr Res 2000;98:15-28.
  • Reneman L, Hahraken JB, Majoie CB, Booij J, den Heeten GJ. MDMA (ecstasy) and its association with cerebrovascular accidents: preliminary findings. Am J Neuroradiol 2000;21:1001-7.
  • Dafters RI, Duffy F, O'Donnell FJ, Bouquet C. Level of use of 3,4-methylenedioxymethamphetamine (MDMA or Ecstasy) in humans correlates with EEG power and coherence. Psychopharmacology (Berlin) 1999;145: 82-90.
  • Gamma A, Frei E, Lehmann D, Pascual-Marqui RD, Hell D, Vollenweider FX. Mood state and brain electric activity in ecstasy users. Neuroreport 2000;11:157-62.
  • Kish SJ, Furukawa Y, Ang L, Vorce SP, Kalasinsky KS. Striatal serotonin is depleted in brain of a human MDMA (Ecstasy) user. Neurology 2000;55:294-6.
  • Curran HV, Travill RA. Mood and cognitive effects of +/-3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"): week-end "high" followed by mid-week low. Addiction 1997;92:821-31.
  • Parrott AC Lasky J. Ecstasy (MDMA) effects upon mood and cognition: before, during and after a Saturday night dance. Psychopharmacology (Berlin) 1998;139:261-8.
  • Klugman A, Hardy S, Baldeweg T, Gruzelier J. Toxic effect of MDMA on brain serotonin neurons. Lancet 1999;3 53:1269-70.
  • Morgan MJ. Recreational use of ecstasy (MDMA) is associated with elevated impulsivity. Neuropsychopharmacology 1998;19:252-64.
  • Parrott AC, Sisk E, Turner JJ. Psychobiological problems in heavy "ecstasy" (MDMA) polydrug users. Drug Alcohol Depend 2000;60:105-10.
  • McCann UD, Ridenour A, Shaham Y, Ricaurte GA. Serotonin neurotoxicity after (+/-)3,4-methylenedioxy-methamphetamine (MDMA; "Ectasy"): a controlled study in humans. Neuropsychopharmacology 1994;10:129-38.
  • Bolla KI, McCann UD, Ricaurte GA. Memory impairment in abstinent MDMA (ecstasy) users. Neurology 1998;51:1532-37.
  • Morgan MJ. Memory deficits associated with recreational use of ecstasy (MDMA). Psychopharmacology (Berlin) 1999;! 41:30-6.
  • McCann UD, MertlM, Eligulashvili V, Ricaurte GA. Cognitive performance in (+/-) 3,4-methyienedioxyme-thamphetamine (MDMA, ecstasy) users: a controlled study. Psychopharmacology (Berlin) 1999;143:417-25.
  • Reneman L, Booij J, Schmand B, van den Brink W, Gunning B. Memory disturbances in ecstasy users are correlated with an altered brain serotonin neurotransmission. Psychopharmacology (Berlin) 2000; 148:3 22-4.
  • WareingM, Fisk JE, Murphy PN. Working memory deficits in current and previous users of MDMA ("cstasy"). Br J Psychol 2000;91:181-8.
  • Gouzoulis-Mayfrank E, Daumann J, Tuchtenhagen F, et al. Impaired cognitive performance in drug free users of recreational ecstasy (MDMA). J Neurol Neurosurg Psychiatry 2000;68:719-25.
  • Rodgers J. Cognitive performance amongst recreational users of ecstasy. Psychopharmacology (Berlin) 2000;151: 19-24.
  • Colado MI, O'Shea E, Granados R, Murray TK, Green AR. In vivo evidence for free radical involvement in the degeneration of rat brain 5-HT following administration of MDMA ("ecstasy") and p-chloroamphetamine but not the degeneration following fenfluramine. Br J Pharmacol 1997;121:889-900.
  • Aguirre N, Barrionuevo M, Ramirez MJ, Del Rio J, Lasheras B. Alpha-lipoic acid prevents 3,4-methylene-dioxy-methamphetamine (MDMA)-induced neurotoxicity. Neuroreport 1999;10:3675-80.
  • Sprague JE, Everman SL, Nichols DR An integrated hypothesis for the serotonergic axonal loss induced by 3,4-methylenedioxymethamphetamine. Neurotoxicology 1998;! 9:427-41.
  • Gerra G, Zaimovic A, FernM, et al. Long-lasting effects of (+/-)3,4-methylenedioxymethamphetamine (ecstasy) on serotonin system function in humans. Biol Psychiatry 2000;47:127-36.
  • Bedford Russell AR, Schwartz RH, Dawling S. Accidental ingestion of "Ecstasy" (3,4-methylenedioxymethylamphetamine). Arch Dis Child 1992;67:1114-15.
  • Cooper A, Egleston CV. Accidental ingestion of Ecstasy by a toddler: unusual cause for convulsion in a febrile child. J Accid Emerg Med 1997;14:183-4.
  • Walubo A, Seger D. Fatal multi-organ failure after suicidal overdose with MDMA, "ecstasy": case report and review of the literature. Hum Exp Toxtcol 1999;18:119-25.
  • Green AR, Cross AJ, Goodwin GM. Review of the pharmacology and clinical pharmacology of 3,4-methyienedioxymethamphetamine (MDMA or "Ecstasy"). Psychopharmacology (Berlin) 1995;119:247-60.
  • Henry JA. Ecstasy and the dance of death. BMJ 1992;305:5-6.
  • Henry JA, Jeffreys KJ, Dawling S. Toxicity and deaths from 3,4-methylenedioxymethamphetaniine ("ecstasy"). Lancet 1992;340:384-7.
  • Milroy CM, Clark JC, Forrest AR. Pathology of deaths associated with ecstasy and "eve" misuse. J Clin Pathol 1996;49:149-53.
  • Parr MJ, Low HM, Botterill P. Hyponatraemia and death after ecstasy ingestion. Med J Aust 1997;166: 136-7.
  • O'Connor A, Cluroe A, Couch R, Galler L, Lawrence J, Synek B. Death from hyponatraemia-induced cerebral oedema associated with MDMA (ecstasy) use. NZ Med J 1999;112:255-6.
  • Holden R, Jackson MA. Near-fatal hyponatraemic coma due to vasopressin over-secretion after ecstasy (3,4-MDMA). Lancet 1996;347:1052.
  • White JM, Bochner F, Irvine RJ. The agony of ecstasy. Med J Aust 1997;166:117-18.
  • Henry JA, Fallen JK, Kicman AT, Hutt AJ, Cowan DA, Forsling M. Low-dose MDMA (ecstasy) induces vasopressin secretion. Lancet 1998;351:1784.
  • Gomez-Balaguer M, Pena H, Morillas C, Hernandez A Syndrome of inappropriate antidiuretic hormone secretion and "designer drugs" (ecstasy). J Pediatr Endocrinol Metab 2000; 13:437-8.
  • Hegadoren KM, Baker GB, Bourin M. 3,4-Methylenedioxy analogues of amphetamine: defining the risks to humans. Neurosci Biobehav Rev 1999;23:539-553.
  • Cimbura G. PMA deaths in Ontario. Can Med Assoc J 1974;110:1263-7.
  • Sawyer J, Stephens WP. Misuse of ecstasy. BMJ 1992;305:310.
  • Watson JD, Ferguson C, Hinds CJ, Skinner R, Coakley JH. Exertional heat stroke induced by amphetamine analogues. Does dantrolene have a place? Anaesthesia 1993;48: 1057-60.
  • Byard RW, Gilbert J, James R, Lokan RJ. Amphetamine derivative fatalities in South Australia--is ecstasy the culprit? Aust J Forensic Med Pathol 1998; 19:261-5.
  • Carter N, Rutty GN, Milroy CM, Forrest AR Deaths associated with MBDB misuse. Int J Legal Med 2000;113:168-70.
  • Suarez RV, Riemersma R. Ecstasy and sudden cardiac death. Am J Forensic Med Pathol 1988;9:339-41.
  • Lora-Tamayo C, Tena T, Rodriguez A Amphetamine derivative related deaths. Forensic Sci Int 1997;85: 149-57.
  • Hanyu S, Ikeguchi K, Imai H, Imai N, Yoshida M. Cerebral infarction associated with 3,4-methyienedioxymethamphetamine ("Ecstasy") abuse. Eur Neural 1995;35:173.
  • Gledhill JA, Moore DF, Bell D, Henry JA. Subarachnoid haemorrhage associated with MDMA abuse. J Neural Neurosurg Psychiatry 1993;56:1036-7.
  • Hughes JC, McCabe M, Evans RJ. Intracranial haemorrhage associated with ingestion of "ecstasy". Arch Emerg Med 1993;10:372-4.
  • Jacks AS, Hykin PG. Retinal haemorrhage caused by ecstasy. Br J Ophthalmol 1998;82:842-3.
  • McEvoy AW, Kitchen ND, Thomas DG. Intracerebral haemorrhage caused by drug abuse. Lancet 1998; 351:1029.
  • Harries DP, de Silva R "Ecstasy" and intracerebral haemorrhage. Scott Med J 1992;37:150-2.
  • Dowling GP, McDonough ET, Bost RO. "Eve" and "Ecstasy": a report of five deaths associated with the use of MDEA and MDMA. JAMA 1987;257:1615-17.
  • Forrest AR, Galloway JH, Marsh ID, Strachan GA, Clark JC. A fatal overdose with 3,4-methylenedioxyaniphetamine derivatives. Forensic Sci Int 1994;64:57-9.
  • Weinmann W, Bohnert M. Lethal monointoxication by overdosage of MDEA. Forensic Sci Int 1998;91:91-101.
  • Dowling GP. Human deaths and toxic reactions attributed to MDMA and MDEA. In: Peroutka SJ, ed. Ecstasy: the clinical, pharmacological and neurotoxicological effects of the drug MDMA. Boston: Kluwer Academic Publishers, 1990:63-75.
  • Cadier MA, Clarke JA. Ecstasy and Whizz at a rave resulting in a major burn plus complications. Burns 1993;19:239-40.
  • Davies JP, Evans RO, Newington DP. Ecstasy related trauma. J Accid Emerg Med 1998;15:436.
  • Levine AJ, Drew S, Rees GM. "Ecstasy" induced pneumomediastinum. J Roy Soc Med 1993;86:232-3.
  • Onwudike M. Ecstasy induced retropharyngeal emphysema. J Accid Emerg Med 1996;13:359-61.
  • Rezvani K, Kurbaan AS, Brenton D. Ecstasy induced pneumomediastinum. Thorax 1996;51:960-1.
  • Pittman JA, Pounsford JC. Spontaneous pneumomediastinum and Ecstasy abuse. J Accid Emerg Med 1997;14:335-6.
  • Ahmed JM, Salame MY, Oakley GD. Chest pain in a young girl. Postgrad Med J 1998;74:115-16.
  • Rittoo P, Rittoo DB. Misuse of ecstasy. BMJ 1992;305:309-10.
  • O'Neill D, Dart JK. Methylenedioxyamphetamine ("Ecstasy") associated keratopathy. Eye 1993;7:805-6.
  • Milosevic A, Agrawal N, Redfearn P, Mair L. The occurrence of toothwear in users of Ecstasy (3,4-methylenedioxymethamphetamine). Community Dent Oral Epidemiol 1999;27:283-7.
  • McElhatton PR, Bateman DN, Evans C, Pughe KR, Thomas SH. Congenital anomalies after prenatal ecstasy exposure. Lancet 1999;54:1441-2.
  • Hall AP. Ecstasy and the anaesthetist. Br J Anaesth 1997;79:697-8.
  • Denborough MA, Hopkinson KC. Dantrolene and ecstasy. Med J Aust 1997; 166:165-6.
  • O'Connor B. Hazards associated with the recreational drug Ecstasy. Br J Hosp Med 1994;52):507-14.
  • Tehan B, Hardern R, Bodenham A. Hyperthermia associated with 3,4-methylenedioxyethamphetamine ("Eve"). Anaesthesia 1993;48:507-10.
  • Selim K, Kaplowitz N. Hepatotoxicity of psychotropic drugs. Hepatology 1999;29:1347-51.
  • Andreu V, Mas A, BrugueraM, et al. Ecstasy: a common cause of severe acute hepatotoxicity. J Hepatol 1998;29:394-7.
  • Jones AL, Simpson KJ. Review article: mechanisms and management of hepatotoxicity in ecstasy (MDMA) and amphetamine intoxications. Aliment Pharmacol Ther 1999;13:129-33.
  • Ellis AJ, Wendon JA, Portmann B, Williams R. Acute liver damage and ecstasy ingestion. Gut 1996;38:454-8.
  • Fidler H, Dhillon A, Gertner D, Burroughs A. Chronic ecstasy (3,4-methylenedioxymetamphetamine) abuse: a recurrent and unpredictable cause of severe acute hepatitis. J Hepatol 1996;25:563-6.
  • Khakoo SI, Coles CJ, Armstrong JS, Barry RE. Hepatotoxicity and accelerated fibrosis following 3,4-methylenedioxymethamphetamine (ecstasy) usage. J Clin Gastroenterol 1995;20:244-7.
  • Curran HV. Is MDMA ("Ecstasy") neurotoxic in humans? An overview of evidence and of methodological problems in research. Neuropsychobiology 2000;42:34-41.
  • Schifano F, Di Furia L, Forza G, Minicuci N, Bricolo R. MDMA ("ecstasy") consumption in the context of polydrug abuse: a report on 150 patients. Drug Alcohol Depend 1998;52:85-90.
  • Cohen RS, Cocores J. Neuropsychiatrie manifestations following the use of 3,4-methylenedioxymethamphetamine (MDMA: ecstasy). Prog Neuropsychopharmacol Biol Psychiatry 1997;21:727-34.
  • Benazzi F, Mazzoli M. Psychiatric illness associated with ecstasy. Lancet 1991;338:1520.
  • Pallanti S, Mazzi D. MDMA (Ecstasy) precipitation of panic disorder. Biol Psychiatry 1992;32:91-5.
  • Williams H, Dratcu L, Taylor R, Roberts M, Oyefeso A. "Saturday night fever": ecstasy related problems in a London accident and emergency department. J Accid Emerg Med 1998;15:322-6.
  • Hardern R, Tehan B. Ecstasy toxicity. J Accid Emerg Med 1995;12:74.
  • Murthy BV, Wilkes RG, Roberts NB. Creatine kinase isoform changes following Ecstasy overdose. Anaesth Intensive Care 1997;25:156-9.
  • Henry JA. Metabolic consequences of drug misuse. Br J Anaesth 2000;85:136-42.
  • Tehan B. Ecstasy and dantrolene. BMJ 1993;306:146.
  • Alciati A, Scaramelli B, Fusi A, Butteri E, Cattaneo ML, Mellado C. Three cases of delirium after ecstasy ingestion. J Psychoactive Drugs 1999;31:167-70.
  • Chenard-Neu MP, Boudjema K, Bernuau J, et al. Auxiliary liver transplantation: regeneration of the native liver and outcome in 30 patients with fulminant hepatic failure--a multicenter European study. Hepatology 1996;23: 1119-27.
  • Topp L, Hando J, Dillon P, Roche A, Solowij N. Ecstasy use in Australia: patterns of use and associated harm. Drug Alcohol Depend 1999;55:105-15.
  • Hunt N, Jones K, Shelley H. What happens when ecstasy is injected? Int J Drug Policy 1993;4:161-2.
  • Stein DJ, Rink J. Effects of ecstasy blocked by serotonin reuptake inhibitors. J Clin Psychiatry 1999;60:485.
  • Kamieniecki G, Vincent N, Allsop S, Lintzeris N. Models of intervention and care for psychostimulant users. National Drug Strategy monograph series no. 32. Canberra, Australia: Commonwealth Department of Health and Family Services, 1998.
  • Barry KL. Brief interventions and brief therapies for substance abuse. Treatment Improvement Protocol (TIP) series no. 34. Rockville, Maryland: US Department of Health and Human Services, 1999.
  • Williamson S, Gossop M, Powis B, Grimms P, Fountain J, Strang J. Adverse effects of stimulant drugs in a community sample of drug users. Drug Alcohol Depend 1997;44:87-94.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.