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Research Article

Synergistic activity of Thymus capitatus essential oil and cefotaxime against ESBL-producing Klebsiella pneumoniae

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Pages 2936-2946 | Received 06 Aug 2023, Accepted 02 Nov 2023, Published online: 12 Nov 2023

References

  • Akrout A, El Jani H, Amouri S, Neffati M. 2010. Screening of antiradical and antibacterial activities of essential oils of artemisia campestris L., artemisia herba alba asso, & thymus capitatus hoff. Et link. Growing wild in the southern of Tunisia. Recent Res in Sci and Technol. 2(1). doi:10.1155/2021/5902851.
  • Alibi S, Selma WB, Mansour HB, Navas J. 2022. Activity of Essential Oils Against Multidrug-Resistant Salmonella enteritidis. Curr Microbiol. 79(9):273. doi: 10.1007/s00284-022-02938-x.
  • Alibi S, Selma WB, Ramos-Vivas J, Smach MA, Touati R, Boukadida J, Mansour HB. 2020. Anti-oxidant, antibacterial, anti-biofilm, and anti-quorum sensing activities of four essential oils against multidrug-resistant bacterial clinical isolates. Curr Res In Transl Medicine. 68(2):59–66. doi: 10.1016/j.retram.2020.01.001.
  • Ali IBEH, Guetat A, Boussaid M. 2012. Chemical and genetic variability of Thymus algeriensis boiss. et reut.(Lamiaceae), a North African endemic species. Ind Crops Prod. 40:277–284. doi: 10.1016/j.indcrop.2012.03.021.
  • Bellakhdar J, Claisse R, Fleurentin J, Younos C. 1991. Repertory of standard herbal drugs in the Moroccan pharmacopoea. J Ethnopharmacol. 35(2):123–143. doi: 10.1016/0378-8741(91)90064-K.
  • Ben Arfa A, Combes S, Preziosi‐Belloy L, Gontard N, Chalier P. 2006. Antimicrobial activity of carvacrol related to its chemical structure. Lett Appl Microbiol. 43(2):149–154. doi: 10.1111/j.1472-765X.2006.01938.x.
  • Bouyahya A, Chamkhi I, Guaouguaou FE, Benali T, Balahbib A, El Omari N, Taha D, El-Shazly M, El Menyiy N. 2020. Ethnomedicinal use, phytochemistry, pharmacology, and food benefits of thymus capitatus. J Ethnopharmacol. 259:112925. doi: 10.1016/j.jep.2020.112925.
  • Cilloniz C, Martin-Loeches I, Garcia-Vidal C, San Jose A, Torres A. 2016. Microbial etiology of pneumonia: epidemiology, diagnosis and resistance patterns. Int J Mol Sci. 17(12):2120. doi: 10.3390/ijms17122120.
  • CLSI. Performance standards for antimicrobial susceptibility testing. 29thed. CLSI Suppl.M100; 2019. 10.1007/978-3-662-48986-4_300416
  • Cowan MM. 1999. Plant products as antimicrobial agents. Clin Microbiol Rev. 12(4):564–582. doi: 10.1128/CMR.12.4.564.
  • Dadgostar P. 2019. Antimicrobial resistance: implications and costs. Infect Drug Resist. 12.3903–3910. doi:10.2147/IDR.S234610.
  • de Kraker ME, Stewardson AJ, Harbarth S. 2016. Will 10 million people die a year due to antimicrobial resistance by 2050? PLoS Med. 13(11):e1002184. doi: 10.1371/journal.pmed.1002184.
  • Dhillon RHP, Clark J. 2012. Esbls: a clear and present danger? Crit Care Res Pract. 2012:1–11. doi: 10.1155/2012/625170.
  • Džamić AM, Nikolić BJ, Giweli AA, Mitić‐Ćulafić DS, Soković MD, Ristić MS, Marin PD. 2015. Libyan Thymus capitatus essential oil: antioxidant, antimicrobial, cytotoxic and colon pathogen adhesion‐inhibition properties. J Appl Microbiol. 119(2):389–399. doi: 10.1111/jam.12864.
  • El Banna H, Soliman M, Al-Wabel PDN. 2013. Hepatoprotective effects of thymus and salvia essential oils on paracetamol-induced toxicity in rats. J Phys Pharm Adv. 3:41. doi: 10.5455/jppa.20130228054608.
  • El-Hilaly J, Hmammouchi M, Lyoussi B. 2003. Ethnobotanical studies and economic evaluation of medicinal plants in taounate province (Northern Morocco). J Ethnopharmacol. 86:149–158. doi: 10.1016/S0378-8741(03)00012-6.
  • El-Mokasabi FM, Al-Sanousi MF, El-Mabrouk RM. 2018. Taxonomy and ethnobotany of medicinal plants in eastern region of libya. J Environ Sci, Toxicol Food Technol. 12:14–23.
  • Eucast definitive document E. Def 1.2, 2000. Terminology relating to methods for the determination of susceptibility of bacteria to antimicrobial agents. European committee for antimicrobial susceptibility testing (EUCAST) of the european society of clinical Microbiology and infectious diseases (ESCMID). 10.1046/j.1469-0691.2000.00149.x
  • Fadli M, Chevalier J, Saad A, Mezrioui NE, Hassani L, Pages JM. 2011. Essential oils from Moroccan plants as potential chemosensitisers restoring antibiotic activity in resistant Gram-negative bacteria. Int J Antimicrob Agents. 38(4):325–330. doi: 10.1016/j.ijantimicag.2011.05.005.
  • Fadli M, Saad A, Sayadi S, Chevalier J, Mezrioui NE, Pagès JM, Hassani L. 2012. Antibacterial activity of Thymus maroccanus and Thymus broussonetii essential oils against nosocomial infection–bacteria and their synergistic potential with antibiotics. Phytomedicine. 19(5):464–471. doi: 10.1016/j.phymed.2011.12.003.
  • Hajlaoui H, Mighri H, Aouni M. 2015. Screening of antibacterial, antifungal and antioxidant activities of Tunisian Thymus capitatus (L.) Hoffm. et link. essential oil. Tunis J Med Plants Nat Prod. 13:20–38. doi: 10.1089/jmf.2009.0117.
  • Hosni K, Hassen I, Chaâbane H, Jemli M, Dallali S, Sebei H, Casabianca H. 2013. Enzyme-assisted extraction of essential oils from thyme (Thymus capitatus L.) and rosemary (Rosmarinus officinalis L.): impact on yield, chemical composition and antimicrobial activity. Ind Crops Prod. 47:291–299. doi: 10.1021/acsomega.2c06713.
  • Jones RN. 2010. Microbial etiologies of hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia. Clin Infect Dis. 51(S1):S81–S87. doi: 10.1086/653053.
  • Limam H, Ben Jemaa M, Tammar S, Ksibi N, Khammassi S, Jallouli S, Del Re G, Msaada K. 2020. Variation in chemical profile of leaves essential oils from thirteen tunisian eucalyptus species and evaluation of their antioxidant and antibacterial properties. Ind Cops Prod. 158:1–11. doi: 10.1016/j.indcrop.2020.112964.
  • Linjawi SA. 2011. Thyme (Thymus capitatus) regulating altered hepatic mRNA expression of apoptotic genes during nickel chloride exposure. Sci J. 4:19–27.
  • Mkaddem MG, Romdhane M, Ibrahim H, Ennajar M, Lebrihi A, Mathieu F, Bouajila J. 2010. Essential oil of thymus capitatus hoff. et link. from matmata, tunisia: gas chromatography-mass spectrometry analysis and antimicrobial and antioxidant activities. J Med Food. 13(6):1500–1504. doi: 10.1089/jmf.2009.0117.
  • Moumni S, Elaissi A, Trabelsi A, Merghni A, Chraief I, Jelassi B, Chemli R, Ferchichi S. 2020. Correlation between chemical composition and antibacterial activity of some Lamiaceae species essential oils from Tunisia. BMC Complement Med Ther. 20(1):103. doi: 10.1186/s12906-020-02888-6.
  • Msaada K, Tammar S, Salem N, Bachrouch O, Sriti J, Hammami M, Selmi S, Azaiez S, Hadj-Brahim A, Al Sane K, et al. 2016. Chemical composition and antioxidant activities of tunisian thymus capitatus l. methanolic extract. Methanolic Extract. 19(6):1381–1390. doi: 10.1080/10942912.2015.1082138.
  • Mustafa B, Hajdari A, Krasniqi F, Hoxha E, Ademi H, Quave CL, Pieroni A. 2012. Medical ethnobotany of the Albanian alps in kosovo. J Ethnobiol Ethnomed. 8:6. doi: 10.1186/1746-4269-8-6.
  • Odds FC. 2003. Synergy, antagonism, and what the chequerboard puts between them. J Antimicrob Chemother. 52(1):1–1. doi: 10.1093/jac/dkg301.
  • Pachón-Ibáñez ME, Labrador-Herrera G, Cebrero-Cangueiro T, Díaz C, Smani Y, Del Palacio JP, Conejo MC. 2018. Efficacy of colistin and its combination with rifampin in vitro and in experimental models of infection caused by carbapenemase-producing clinical isolates of Klebsiella pneumoniae. Front Microbiol. 9:912. doi: 10.3389/fmicb.2018.00912.
  • Pandey AK, Singh P, Tripathi NN. 2014. Chemistry and bioactivities of essential oils of some ocimum species: an overview. Asian Pac J Trop Biomed. 4(9):682–694. doi: 10.3390/molecules27196350.
  • Pankey GA, Sabath LD. 2004. Clinical relevance of bacteriostatic versus bactericidal mechanisms of action in the treatment of Gram-positive bacterial infections. Clin Infect Dis. 1538(6):864–870. doi: 10.1086/381972.
  • Pitout JDD. 2012. Extraintestinal pathogenic Escherichia coli: a combination of virulence with antibiotic resistance. Front Microbiol. 3:9. doi: 10.3389/fmicb.2012.00009.
  • Ponce AG, Fritz R, Del Valle C, Roura SI. 2003. Antimicrobial activity of essential oils on the native microflora of organic Swiss chard. Lwt-Food Sci Technol. 36(7):679–684. doi: 10.1016/S0023-6438(03)00088-4.
  • Salah-Fatnassi KBH, Slim-Bannour A, Harzallah-Skhiri F, Mahjoub MA, Mighri Z, Chaumont J-P, Aouni M. 2010. Activités antivirale et antioxydante in vitro d’huiles essentielles de Thymus capitatus (L.) Hoffmans. & Link de Tunisie. & Link de Tunisie Acta Bot Gall. 157(3):433–444. doi: 10.1080/12538078.2010.10516220.
  • Saoudi S, Sifaoui I, Chammem N, Reyes-Batlle M, López-Arencibia A, Pacheco-Fernández I, Pino V, Hamdi M, Jiménez IA, Bazzocchi IL, et al. 2017. Anti- acanthamoeba activity of Tunisian Thymus capitatus essential oil and organic extracts. Exp Parasitol. 183:231–235. doi: 10.1016/j.exppara.2017.09.014.
  • Skotti E, Anastasaki E, Kanellou G, Polissiou M, Tarantilis PA. 2014. Total phenolic content, antioxidant activity and toxicity of aqueous extracts from selected Greek medicinal and aromatic plants. Ind Crops Prod. 53:46–54. doi: 10.1007/s13205-017-0706-9.
  • Tagnaout I, Zerkani H, Hadi N, El Moumen B, El Makhoukhi F, Bouhrim M, Al-Salahi R, Nasr FA, Mechchate H, Zair T. 2022. Chemical composition, antioxidant and antibacterial activities of Thymus broussonetii boiss and Thymus capitatus. (L) Hoffmann And Link Essential Oils Plants (Basel). 11(7):954. doi: 10.3390/plants11070954.
  • Tammar S, Salem N, Bettaieb Rebey I, Sriti J, Hammami M, Khammassi S, Msaada K 2018. Regional effect on essential oil composition and antimicrobial activity of thymus capitatus L. J Essent Oil Res. 31(2):129–137. doi: 10.3390/molecules27248791.
  • Tiwari V, Roy R, Tiwari M. 2015. Antimicrobial active herbal compounds against acinetobacter baumannii and other pathogens. Front Microbiol. 6:618. doi: 10.3389/fmicb.2015.00618.
  • Toujani MM, Rittà M, Civra A, Genovese S, Epifano F, Ghram A, Lembo D, Donalisio M. 2018. Inhibition of HSV-2 infection by pure compounds from Thymus capitatus extract in vitro. Phytother Res. 32(8):1555–1563. doi: 10.1002/ptr.6084.
  • Trifan A, Luca SV, Greige-Gerges H, Miron A, Gille E, Aprotosoaie AC. 2020. Recent advances in tackling microbial multidrug resistance with essential oils: combinatorial and nano-based strategies. Crit Rev Microbiol. 46(3):338–357. doi: 10.1080/1040841X.2020.1782339.
  • Vardar-Ünlü G, Candan F, Sökmen A, Daferera D, Polissiou M, Sökmen M, Tepe B. 2003. Antimicrobial and antioxidant activity of the essential oil and methanol extracts of Thymus pectinatus Fisch. et Mey. Var Pectinatus (Lamiaceae) J Agric Food Chem. 51(1):63–67. doi: 10.1021/jf025753e.
  • Vázquez-Ucha JC, Martínez-Guitián M, Lasarte-Monterrubio C, Conde-Pérez K, Arca-Suárez J, Álvarez-Fraga L, Beceiro A. 2020. Syzygium aromaticum (clove) and Thymus zygis (thyme) essential oils increase susceptibility to colistin in the nosocomial pathogens acinetobacter baumannii and Klebsiella pneumoniae. Biomed Pharmacother. 130:110606. doi: 10.1016/j.biopha.2020.110606.
  • WHO. 2017. Global priority list of antibiotic-resistant bacteria to guide Research, discovery and development of New antibiotics, World Heal. Organ. 10.1016/S1473-3099(09)70222-1.
  • Zaïri A, Nouir S, Zarrouk A, Haddad H, Khélifa A, Achour L, Tangy F, Chaouachi M, Trabelsi M. 2019. Chemical composition, fatty acids profile and biological properties of Thymus capitatus (L.) hoffmanns, essential oil. Sci Rep. 9(1):20134. doi: 10.1038/s41598-019-56580-y.

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