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International Journal of Environmental Health Research Volume 9, 1999 - Issue 1
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Original Articles

Respiratory health effects of nitrogen dioxide exposure and current guidelines

Monika Nitschke
Pages 39-53 | Published online: 21 Jul 2010

  • Anderson , H.R. , Limb , E.S. , Bland , J.M. , Ponce de Leon , A. , Strachan , D.P. and Bower , J.S. 1995 . Health effects of an air pollution episode in London, December 1991 . Thorax , 50 : 1188 – 93 .
  • Australian Bureau of Statistics . 1997 . Report No. ABS Catalogue No. 4364.0 , Canberra : Australian Bureau of Statistics .
  • Bauer , M.A. , Utell , M.J. , Morrow , P.E. , Speers , D.M. and Gibb , F.R. 1986 . Inhalation of 0.30ppm nitrogen dioxide potentiates exercise-induced bronchospasm in asthmatics' . Am. Rev. Respir. Dis. , 134 : 1203 – 8 .
  • Berglund , M. 1993 . Health risk evaluation of nitrogen oxides . Skandinavian Journal of Work, Environment & Health , 19 (suppl. 2) : 37 – 43 .
  • Berwick , M. , Leaderer , B.P. and Stolwijk , J.A. 1989 . Lower respiratory symptoms in children exposed to nitrogen dioxide from unvented combustion sources . Environment International , 15 : 369 – 373 .
  • Braun-Fahrländer , C. , Ackermann-Liebrich , U. , Schwartz , J. , Gnehm , H.P. , Rutishauser , M. and Wanner , H.U. 1992 . Air Pollution and respiratory symptoms in preschool children . Am. Rev. Respir. Dis. , 145 : 42 – 47 .
  • Brunekreef , B. , Dockery , D.W. and Kryzanowski , M. 1995 . Epidemiologic studies on short-term effects of low levels of major ambient air pollution components . Environmental Health Perspectives , 103 (suppl. 2) : 3 – 13 .
  • Castellsague , J. , Sunyer , J. , Saez , M. and Anto , J.M. 1995 . Short-term association between air pollution and emergency room visits for asthma in Barcelona . Thorax , 50 : 1051 – 6 .
  • Committee of the Environmental and Occupational Health Assembly of the American Thoracic Society . 1996 . Health effects of outdoor air pollution . Am. J. Respir. Crit. Care. Med. , 153 : 3 – 50 .
  • Dekker , C. , Dales , R. , Bartlett , S. , Brunekreef , B. and Zwanenburg , H. 1991 . Childhood asthma and the indoor environment . Chest , 100 : 922 – 6 .
  • Devalia , J.L. , Rusznak , C. , Herdman , M.J. , Trigg , C.J. , Tarraf , H. and Davies , R.J. 1994 . Effect of nitrogen dioxide and sulphur dioxide on airway response of mild asthmatic patients to allergen inhalation . Lancet , 344 : 1668 – 71 .
  • Dijkstra , L. , Houthuijs , D. , Brunekreef , B. , Akkerman , I. and Boleij , J.S. 1990 . Respiratory health effects of the indoor environment in a population of Dutch children . Am. Rev. Respir. Dis. , 142 : 1172 – 8 .
  • 1987 . Federal-Provincial Advisory Committee on Environmental and Occupational Health , Ottawa : Minister of Supply and Services Canada .
  • Florey , C.V. , Melia , R.J. , Chinn , S. , Goldstein , B.D. , Brooks , A.C. , John , H.H. , Craighead , L.B. and Webster , X. 1979 . The relation between respiratory illness in primary schoolchildren and the use of gas for cooking-III. Nitrogen dioxide, respiratory illness and lung infection . Int. J. Epidemiol. , 8 : 347 – 53 .
  • Folinsbee , L.J. 1992 . Does nitrogen dioxide exposure increase airways responsiveness? Toxicol . Ind. Health , 8 : 273 – 83 .
  • Forsberg , B. , Stjemberg , N. , FaIk , M. , Lundback , B. and Wall , S. 1993 . Air pollution levels, meteorological conditions and asthma symptoms . Eur. Respir. J. , 6 : 1109 – 15 .
  • Frischer , T. , Studnicka , M. , Hesse , P. , Gitsch , G. , Mutschlechner , R. and Neumann , M. 1989 . Air pollutants and bronchial reactivity in primary school children 1 . Wien. Med. Wochenschr. Suppl , 104 (suppl. 43) : 4
  • Frischer , T. , Studnicka , M , Beer , E. and Neumann , M. 1993 . The effects of ambient nitrogen dioxide on lung function in primary schoolchildren . Environ. Res. , 62 : 179 – 88 .
  • Goldstein , B.D. , Melia , R.J. , Chinn , S. , Florey , C.V. , Clark , D. and John , H.H. 1979 . The relation between respiratory illness in primary schoolchildren and the use of gas for cooking-II. Factors affecting nitrogen dioxide levels in the home . Int. J. Epidemiol. , 8 : 339 – 45 .
  • Harrington , W. and Krupnick , A.J. 1985 . Short-term nitrogen dioxide exposure and acute respiratory disease in children . Journal of the Air Pollution Control Association , 35 : 1061 – 7 .
  • Hasselblad , V. , Eddy , D.M. and Kotchmar , D.J. 1992 . Synthesis of environmental evidence: nitrogen dioxide epidemiology studies . J. Air Waste. Manage. Assoc. , 42 : 662 – 71 .
  • Henry , R.L. , Bridgman , H.A. , Wlodarczyk , J. , Abramson , R. , Adler , J.A. and Hensley , M.J. 1991 . Asthma in the vicinity of power stations: II.outdoor air quality and symptoms . Pediatric Pulmonology , 11 : 134 – 40 .
  • Hoek , G. , Brunekreef , B. , Meijer , R. , Scholten , A. and Boleij , J. 1984 . Indoor nitrogen dioxide pollution and respiratory symptoms of schoolchildren . Int. Arch. Occup. Environ. Health , 55 : 79 – 86 .
  • Houthuijs , D. , Remijn , B. , Brunekreef , B. and DeKoning , R. 1987 . Exposure to nitrogen dioxide and tobacco smoke and respiratory health of children . Indoor Air , 1 : 463 – 7 .
  • Infante Rivard , C. 1993 . Childhood asthma and indoor environmental risk factors . Am. J. Epidemiol. , 137 : 834 – 44 .
  • Jarvis , D. , Chinn , S. , Luczynska , C. and Burney , P. 1996 . Association of respiratory symptoms and lung function in young adults with use of domestic gas appliances . Lancet , 347 : 426 – 31 .
  • Jedrychowski , W. , Khogali , M. and Elkarim , M.A. 1991 . Height and lung function in préadolescent children of Kuwaitis and European origin: a pilot survey on health effects of gas cooking in the Middle East . Arch. Environ. Health , 46 : 361 – 5 .
  • Kagamimori , S. , Katoh , T , Naruse , Y. , Watanabe , M. , Kasuya , M. , Shinkai , J. and Kawano , S. 1986 . The changing prevalence of respiratory symptoms in atopic children in response to air pollution . Clinical Allergy , 16 : 299 – 308 .
  • Koo , L.C. , Ho , J.H. , Ho , C.Y. , Matsuki , H. , Shimizu , H. , Mori , T. and Tominaga , S. 1990 . Personal exposure to nitrogen dioxide and its association with respiratory illness in Hong Kong . Am. Rev. Respir. Dis. , 141 : 1119 – 26 .
  • Koren , H.S. 1995 . Associations between criteria air pollutants and asthma . Environ. Health. Perspect. , 103 (Suppl. 6) : 235 – 42 .
  • Kuhr , J. , Hendel Kramer , A. , Karmaus , W. , Moseler , M. , Weiss , K. , Stephan , V. and Urbanek , R. 1991 . Air pollutant burden and bronchial asthma in school children . Soz. Praventivmed. , 36 : 67 – 73 .
  • Lebowitz , M.D. , O'Rourke , M.K. , Holberg , C.J. , Corman , G. , Hoshaw , R.W. , Pinnas , J.L. , Barbee , R.A. and Sneller , M.R. 1982 . The adverse health effects of biological aerosols, other aerosols, and indoor microclimate on asthmatics and nonasthmatics . Environment International , 8 : 375 – 80 .
  • Lebowitz , M.D. , Collins , L. and Holberg , C.J. 1987 . Time series analyses of respiratory responses to indoor and outdoor environmental phenomena . Environ. Res. , 43 : 332 – 41 .
  • Leynaert , B. , Liard , R. , Bousquet , J. , Mesbah , H. and Neukirch , F. 1996 . Gas cooking and respiratory health in women . Lancet , 347 : 1052 – 3 .
  • Love , G.J. , Lan , S.P. , Shy , C.M. and Riggan , W.B. 1982 . Acute respiratory illness in families exposed to nitrogen dioxide ambient air pollution in Chattanooga, Tennessee . Arch. Environ. Health , 37 : 75 – 80 .
  • Melia , R.J. , Florey C du , V. , Morris , R.W. , Goldstein , B.D. , John , H.H. , Clark , D. , Craighead , LB. and Mackinlay , J.C. 1982 . Childhood respiratory illness and the home environment. II. Association between respiratory illness and nitrogen dioxide, temperature and relative humidity . Int. J. Epidemiol. , 11 : 164 – 9 .
  • Moseholm , L. , Taudorf , E. and Frosig , A. 1993 . Pulmonary function changes in asthmatics associated with low-level SO2 and NO2 air pollution, weather, and medicine intake. An 8-month prospective study analyzed by neural networks . Allergy , 48 : 334 – 44 .
  • Moseler , M. , Hendel Kramer , A. , Karmaus , W. , Forster , J. , Weiss , K. , Urbanek , R. and Kuehr , J. 1994 . Effect of moderate NO2 air pollution on the lung function of children with asthmatic symptoms . Environ. Res. , 67 : 109 – 24 .
  • Mostardi , R.A. , Ely , D.L. , Woebkenberg , N.R. , Richardson , B. and Jarrett , M.T. 1981 . The University of Akron study on air pollution and human health effects I. Methodology, baseline data, and aerometrics . Arch. Environ. Health , 36 : 243 – 9 .
  • Neas , L.M. , Dockery , D.W. , Ware , J.H. , Spengler , J.D. , Speizer , FE. and Ferris , B. G. Jr. 1991 . Association of indoor nitrogen dioxide with respiratory symptoms and pulmonary function in children . Am. J. Epidemiol. , 134 : 204 – 19 .
  • Ng , T.P. , Hui , K.P. and Tan , W.C. 1993 . Respiratory symptoms and lung function effects of domestic exposure to tobacco smoke and cooking by gas in non-smoking women in Singapore . J. Epidemiol. Community. Health , 47 : 454 – 8 .
  • Orehek , J. , Massari , J.P. , Gayrard , P. , Grimaud , C. and Charpin , J. 1976 . Effect of short-term, low-level nitrogen dioxide exposure on bronchial sensitivity of asthmatic patients . J. Clin. Invest. , 57 : 301 – 7 .
  • Ostro , B.D. , Lipsett , M.J. , Mann , J.K. , Wiener , M.B. and Seiner , J. 1994 . Indoor air pollution and asthma. Results from a panel study . Am. J. Respir. Crit. Care. Med. , 149 : 1400 – 6 .
  • Ostro , B.D. , Lipsett , M.J. , Mann , J.K. , Krupnick , A. and Harrington , W. 1993 . Air pollution and respiratory morbidity among adults in Southern California . American Journal of Epidemiology , 137 : 691 – 700 .
  • Pearlman , M.E. , Finklea , J.F. and Creason , J.P. 1971 . Nitrogen dioxide and lower respiratory illness . Paediatrics , 47 : 391 – 8 .
  • Pilotto , L.S. 1994 . “ Indoor nitrogen dioxide exposure and respiratory illness in children ” . Canberra : The Australian National University . Thesis,
  • Pilotto , L.S. and Douglas , R.M. 1992 . Indoor nitrogen dioxide and childhood respiratory illness . Aust J. Public. Health , 16 : 245 – 50 .
  • Pilotto , L.S. , Douglas , R. , Attewell , R. and Wilson , S. 1997 . Respiratory effects associated with indoor nitrogen dioxide exposure in children . Int. J. Epidemiol. , 26 (4) : 788 – 95 .
  • Ponka , A. 1991 . Asthma and low level air pollution in Helsinki . Arch. Environ. Health , 46 : 262 – 70 .
  • Quackenboss , J.J. , Kanarek , M.S. , Spengler , J.D. and Letz , R. 1982 . Personal monitoring for nitrogen dioxide exposure: methodological considerations for a community study . Environment International , 8 : 249 – 58 .
  • Rossi , O.V. , Kinnula , V.L. , Tienari , J. and Huhti , E. 1993 . Association of severe asthma attacks with weather, pollen, and air pollutants . Thorax , 48 : 244 – 8 .
  • Rusznak , C. , Devalia , L. and Davies , R.J. 1996 . Airway response of asthmatic subjects to inhaled allergen after exposure to pollutants . Thorax , 51 : 1105 – 8 .
  • Rutishauser , M. , Ackermann , U. , Braun , C.H. , Gnehm , H.P. and Wanner , H.U. 1990 . Significant association between outdoor nitrogen dioxide and respiratory symptoms in preschool children . Lung , : 347 – 352 .
  • Samet , J.M. and Utell , M.J. 1990 . The risk of nitrogen dioxide: what have we learned from epidemiological and clinical studies? Toxicol . Ind. Health , 6 : 247 – 62 .
  • Samet , J.M. , Lambert , W.E. , Skipper , B.J. , Cushing , A.H. , Hunt , W.C. , Young , S. A. , McLaren , L.C. , Schwab , M. and Spengler , J.D. 1993 . Nitrogen dioxide and respiratory illness in children. Part I: Health outcomes . Res. Rep. Health. Eff. Inst. , June : 1 – 32 . 51 – 80 .
  • 1996 . Review Manager (Version Version 3.0 for Windows.) , Oxford, , UK : The Cochrane Collaboration . [Computer program],
  • Schwartz , J. 1989 . Lung function and chronic exposure to air pollution: a cross-sectional analysis of NHANES II . Environ. Res. , 50 : 309 – 21 .
  • Schwartz , J. and Zeger , S. 1990 . Passive smoking, air pollution, and acute respiratory symptoms in a diary study of student nurses . Am. Rev. Respir. Dis. , 141 : 62 – 7 .
  • Schwanz , J. , Wypij , D. , Dockery , D. , Ware , J. , Zeger , S. , Spengler , J. and Ferris , B. Jr. 1991 . 'Daily diaries of respiratory symptoms and air pollution: methodological issues and results . Environ. Health. Perspect. , 90 : 181 – 7 .
  • Shy , CM. , Creason , J.P. , Pearlman , M.E. , McClain , K.E. , Benson , F.B. and Young , M.M. 1970 . The Chattanooga school children study: effects of community exposure to nitrogen dioxide. II. Incidence of acute respiratory illness . J. Air Pollut. Control Assoc. , 20 : 582 – 8 .
  • Speizer , F.E. , Ferris , B. , Bishop , Y.M.M. and Spengler , J. 1980 . Respiratory disease rates and pulmonary function in children associated with nitrogen dioxide exposure . Am. Rev. Respir. Dis. , 121 : 3 – 10 .
  • Strand , V. , Rak , S. , Svartengren , M. and Bylin , G. 1997 . Nitrogen dioxide exposure enhances asthmatic reaction to inhaled allergen in subjects with asthma . Am. J. of Res. & Crit. Care Med. , 155 : 881 – 7 .
  • Tunnicliffe , W.S. , Burge , P.S. and Ayres , J.G. 1994 . Effect of domestic concentrations of nitrogen dioxide on airway responses to inhaled allergen in asthmatic patients . Lancet , 344 : 1733 – 6 .
  • Utell , M.J. and Frank , R. 1989 . “ Susceptibility to inhaled pollutants, ASTM STP 1024 ” . In Asthma and Nitrogen Dioxide: A Review of the Evidence , 218 – 223 . Philadelphia : American Society for Testing and Materials .
  • Vedal , S. , Schenker , M.B. , Munoz , A. , Samet , J. , Batterman , S. and Speizer , FE. 1987 . Daily air pollution effects on children's respiratory symptoms and peak expiratory flow . American Journal of Public Health , 77 : 694 – 8 .
  • Volkmer , R.E. , Ruffin , R.E. , Wigg , N.R. and Davies , N. 1995 . The prevalence of respiratory symptoms in South Australian preschool children. II. Factors associated with indoor air quality . J. Paediatr. Child Health , 31 : 116 – 20 .
  • von Mutius , E. , Sherrill , D.L. , Fritzsch , C. , Martinez , FD. and Lebowitz , M.D. 1995 . Air pollution and upper respiratory symptoms in children from East Germany . Eur. Respir. J. , 8 : 723 – 8 .
  • Walters , S. , Phupinyokul , M. and Ayres , J. 1995 . Hospital admission rates for asthma and respiratory disease in the West Midlands: their relationship to air pollution levels . Thorax , 50 : 948 – 54 .
  • Wieringa , M. , Weyler , J. and Vermeire , P. 1996 . Absence of association between respiratory symptoms in young adults and use of gas stoves in Belgium . The Lancet , 347 : 1490 – 1 .
  • World Health Organization (WHO) . 1997 . International Programme on Chemical Safety Geneva

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