484
Views
47
CrossRef citations to date
0
Altmetric
In Vitro and Animal Studies

Inhibition of green tea polyphenol EGCG((−)-epigallocatechin-3-gallate) on the proliferation of gastric cancer cells by suppressing canonical wnt/β-catenin signalling pathway

, &
Pages 818-827 | Received 23 Mar 2016, Accepted 04 Jun 2016, Published online: 24 Jun 2016

References

  • Bhatti SK, O’keefe JH, Lavie CJ. 2013. Coffee and tea: perks for health and longevity? Curr Opin Clin Nutrit Metab Care. 16:688–697.
  • Chen XF, Qian J, Pei D, Zhou C, Roe OD, Zhu F, He SH, Qian YY, Zhou Y, Xu J, et al. 2016. Prognostic value of perioperative leukocyte count in resectable gastric cancer. World J Gastroenterol. 22:2818–2827.
  • Clements WM, Wang J, Sarnaik A, Kim OJ, Macdonald J, Fenoglio-Preiser C, Groden J, Lowy AM. 2002. beta-Catenin mutation is a frequent cause of Wnt pathway activation in gastric cancer. Cancer Res. 62:3503–3506.
  • Clevers H, Nusse R. 2012. Wnt/β-catenin signaling and disease. Cell. 149:1192–1205.
  • Crespy V, Williamson G. 2004. A review of the health effects of green tea catechins in in vivo animal models. J Nutr. 134:3431S–3440S.
  • Czyzewska J, Guzinska-Ustymowicz K, Ustymowicz M, Pryczynicz A, Kemona A. 2010. The expression of E-cadherin-catenin complex in patients with advanced gastric cancer: role in formation of metastasis. Folia Histochem Cytobiol. 48:37–45.
  • Dashwood WM, Carter O, Al-Fageeh M, Li Q, Dashwood RH. 2005. Lysosomal trafficking of beta-catenin induced by the tea polyphenol epigallocatechin-3-gallate. Mutat Res. 591:161–172.
  • Gough NR. 2012. Focus issue: Wnt and β-catenin signaling in development and disease. Sci Signal. 5:eg2.
  • Guo J, Fu Z, Wei J, Lu W, Feng J, Zhang S. 2015. PRRX1 promotes epithelial-mesenchymal transition through the Wnt/β-catenin pathway in gastric cancer. Med Oncol. 32:393.
  • Gwak J, Jung SJ, Kang DI, Kim EY, Kim DE, Chung YH, Shin JG, Oh S. 2009. Stimulation of protein kinase C-alpha suppresses colon cancer cell proliferation by down-regulation of beta-catenin. J Cell Mol Med. 13:2171–2180.
  • Han YM, Park JM, Jeong M, Yoo JH, Kim WH, Shin SP, Ko WJ, Hahm KB. 2015. Dietary, non-microbial intervention to prevent Helicobacter pylori-associated gastric diseases. Ann Transl Med. 3:122.
  • Henning SM, Wang P, Carpenter CL, Heber D. 2013. Epigenetic effects of green tea polyphenols in cancer. Epigenomics. 5:729–741.
  • Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. 2011. Global cancer statistics. CA Cancer J Clin. 61:69–90.
  • Jeong M, Park JM, Han YM, Kangwan N, Kwon SO, Kim BN, Kim WH, Hahm KB. 2016. Dietary intervention of artemisia and green tea extracts to rejuvenate Helicobacter pylori-associated chronic atrophic gastritis and to prevent tumorigenesis. Helicobacter. 21:40–59.
  • Jia S, Cai J. 2016. Update on biomarkers in development of anti-angiogenic drugs in gastric cancer. Anticancer Res. 36:1111–1118.
  • Kim J, Zhang X, Rieger-Christ KM, Summerhayes IC, Wazer DE, Paulson KE, Yee AS. 2006. Suppression of Wnt signaling by the green tea compound (-)-epigallocatechin 3-gallate (EGCG) in invasive breast cancer cells. Requirement of the transcriptional repressor HBP1. J Biol Chem. 281:10865–10875.
  • Koizumi W, Narahara H, Hara T, Takagane A, Akiya T, Takagi M, Miyashita K, Nishizaki T, Kobayashi O, Takiyama W, et al. 2008. S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): a phase III trial. Lancet Oncol. 9:215–221.
  • Logan CY, Nusse R. 2004. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol. 20:781–810.
  • Nusse R. 2005. Wnt signaling in disease and in development. Cell Res. 15:28–32.
  • Ochoa-Hernandez AB, Juarez-Vazquez CI, Rosales-Reynoso MA, Barros-Nunez P. 2012. WNT-beta-catenin signaling pathway and its relationship with cancer. Cir Cir. 80:389–398.
  • Ogunleye AA, Xue F, Michels KB. 2010. Green tea consumption and breast cancer risk or recurrence: a meta-analysis. Breast Cancer Res Treat. 119:477–484.
  • Oh S, Gwak J, Park S, Yang CS. 2014. Green tea polyphenol EGCG suppresses Wnt/β-catenin signaling by promoting GSK-3β- and PP2A-independent β-catenin phosphorylation/degradation. Biofactors. 40:586–595.
  • Pan KF, Liu WG, Zhang L, You WC, Lu YY. 2008. Mutations in components of the Wnt signaling pathway in gastric cancer. World J Gastroenterol. 14:1570–1574.
  • Patel R, Ingle A, Maru GB. 2008. Polymeric black tea polyphenols inhibit 1,2-dimethylhydrazine induced colorectal carcinogenesis by inhibiting cell proliferation via Wnt/beta-catenin pathway. Toxicol Appl Pharmacol. 227:136–146.
  • Polakis P. 2012. Wnt signaling in cancer. Cold Spring Harb Perspect Biol. 4:1–13.
  • Rahman R, Asombang AW, Ibdah JA. 2014. Characteristics of gastric cancer in Asia. World J Gastroenterol. 20:4483–4490.
  • Sasako M, Sakuramoto S, Katai H, Kinoshita T, Furukawa H, Yamaguchi T, Nashimoto A, Fujii M, Nakajima T, Ohashi Y. 2011. Five-year outcomes of a randomized phase III trial comparing adjuvant chemotherapy with S-1 versus surgery alone in stage II or III gastric cancer. J Clin Oncol. 29:4387–4393.
  • Sereno M, De Castro J, Cejas P, Garcia-Cabezas MA, Belda C, Casado E, Feliu J, Gómez C, López M, Barón MG. 2012. Expression profile as predictor of relapse after adjuvant treatment in gastric cancer. J Gastrointest Cancer. 43:181–189.
  • Sherwood V. 2015. WNT signaling: an emerging mediator of cancer cell metabolism? Mol Cell Biol. 35:2–10.
  • Shirakami Y, Shimizu M, Moriwaki H. 2012. Cancer chemoprevention with green tea catechins: from bench to bed. Curr Drug Targets. 13:1842–1857.
  • Singh BN, Shankar S, Srivastava RK. 2011. Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications. Biochem Pharmacol. 82:1807–1821.
  • Sugano K. 2015. Screening of gastric cancer in Asia. Best Pract Res Clin Gastroenterol. 29:895–905.
  • Wodarz A, Nusse R. 1998. Mechanisms of Wnt signaling in development. Annu Rev Cell Dev Biol. 14:59–88.
  • Yang CS, Wang H. 2011a. Mechanistic issues concerning cancer prevention by tea catechins. Mol Nutr Food Res. 55:819–831.
  • Yang CS, Wang H, Li GX, Yang Z, Guan F, Jin H. 2011b. Cancer prevention by tea: evidence from laboratory studies. Pharmacol Res. 64:113–122.
  • Zhang H, Xue Y. 2008. Wnt pathway is involved in advanced gastric carcinoma. Hepatogastroenterology. 55:1126–1130.
  • Zou Y, Salinas P. 2014. Introduction: Wnt signaling mechanisms in development and disease. Dev Neurobiol. 74:757–758.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.