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Studies in Humans

Anthropometric and metabolic improvements in human type 2 diabetes after introduction of an Okinawan-based Nordic diet are not associated with changes in microbial diversity or SCFA concentrations

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Pages 729-740 | Received 29 Sep 2017, Accepted 17 Nov 2017, Published online: 04 Dec 2017

References

  • Allin KH, Nielsen T, Pedersen O. 2015. Mechanisms in endocrinology: gut microbiota in patients with type 2 diabetes mellitus. Eur J Endocrinol. 172:R167–R177.
  • Arora T, Backhed F. 2016. The gut microbiota and metabolic disease: current understanding and future perspectives. J Intern Med. 280:339–349.
  • Baothman OA, Zamzami MA, Taher I, Abubaker J, Abu-Farha M. 2016. The role of gut microbiota in the development of obesity and diabetes. Lipids Health Dis. 15:108.
  • Bartosch S, Fite A, Macfarlane GT, McMurdo ME. 2004. Characterization of bacterial communities in feces from healthy elderly volunteers and hospitalized elderly patients by using real-time PCR and effects of antibiotic treatment on the fecal microbiota. Appl Environ Microbiol. 70:3575–3581.
  • Castillo M, Martin-Orue SM, Manzanilla EG, Badiola I, Martin M, Gasa J. 2006. Quantification of total bacteria, enterobacteria and lactobacilli populations in pig digesta by real-time PCR. Vet Microbiol. 114:165–170.
  • Cuervo A, Salazar N, Ruas-Madiedo P, Gueimonde M, Gonzalez S. 2013. Fiber from a regular diet is directly associated with fecal short-chain fatty acid concentrations in the elderly. Nutr Res. 33:811–816.
  • Cummings JH, Macfarlane GT. 1997. Role of intestinal bacteria in nutrient metabolism. JPEN J Parenter Enteral Nutr. 21:357–365.
  • Darwiche G, Hoglund P, Roth B, Larsson E, Sjoberg T, Wohlfart B, Steen S, Ohlsson B. 2016. An Okinawan-based Nordic diet improves anthropometry, metabolic control, and health-related quality of life in Scandinavian patients with type 2 diabetes: a pilot trial. Food Nutr Res. 60:32594.
  • den Besten G, Lange K, Havinga R, van Dijk TH, Gerding A, van Eunen K, Muller M, et al. 2013. Gut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids. Am J Physiol Gastrointest Liver Physiol. 305:G900–G910.
  • Flint HJ, Scott KP, Louis P, Duncan SH. 2012. The role of the gut microbiota in nutrition and health. Nat Rev Gastroenterol Hepatol. 9:577–589.
  • Freeland KR, Wilson C, Wolever TM. 2010. Adaptation of colonic fermentation and glucagon-like peptide-1 secretion with increased wheat fibre intake for 1 year in hyperinsulinaemic human subjects. Br J Nutr. 103:82–90.
  • Freeland KR, Wolever TM. 2010. Acute effects of intravenous and rectal acetate on glucagon-like peptide-1, peptide YY, ghrelin, adiponectin and tumour necrosis factor-alpha. Br J Nutr. 103:460–466.
  • Gao Z, Yin J, Zhang J, Ward RE, Martin RJ, Lefevre M, Cefalu WT, Ye J. 2009. Butyrate improves insulin sensitivity and increases energy expenditure in mice. Diabetes. 58:1509–1517.
  • Graf D, Di Cagno R, Fak F, Flint HJ, Nyman M, Saarela M, Watzl B. 2015. Contribution of diet to the composition of the human gut microbiota. Microb Ecol Health Disease. 26:26164.
  • Holman RR, Paul SK, Bethel MA, Matthews DR, Neil HAW. 2008. 10-year follow-up of intensive glucose control in type 2 diabetes [Article]. N Engl J Med. 359:1577–1589.
  • Ibrugger S, Vigsnaes LK, Blennow A, Skuflic D, Raben A, Lauritzen L, Kristensen M. 2014. Second meal effect on appetite and fermentation of wholegrain rye foods. Appetite. 80:248–256.
  • Jakobsdottir G, Bjerregaard JH, Skovbjerg H, Nyman M. 2013. Fasting serum concentration of short-chain fatty acids in subjects with microscopic colitis and celiac disease: no difference compared with controls, but between genders [Article]. Scand J Gastroenterol. 48:696–701.
  • Jakobsdottir G, Jadert C, Holm L, Nyman ME. 2013. Propionic and butyric acids, formed in the caecum of rats fed highly fermentable dietary fibre, are reflected in portal and aortic serum [Article]. Br J Nutr. 110:1565–1572.
  • Karaderi T, Drong AW, Lindgren CM. 2015. Insights into the genetic susceptibility to type 2 diabetes from genome-wide association studies of obesity-related traits. Curr Diab Rep. 15:83.
  • Karlsson CL, Onnerfalt J, Xu J, Molin G, Ahrne S, Thorngren-Jerneck K. 2012. The microbiota of the gut in preschool children with normal and excessive body weight. Obesity. 20:2257–2261.
  • Karlsson FH, Tremaroli V, Nookaew I, Bergstrom G, Behre CJ, Fagerberg B, Nielsen J, Backhed F. 2013. Gut metagenome in European women with normal, impaired and diabetic glucose control. Nature. 498:99–103.
  • Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA, Nathan DM, Diabetes Prevention Program Research Group. 2002. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 346:393–403.
  • Knowles SE, Jarrett IG, Filsell OH, Ballard FJ. 1974. Production and utilization of acetate in mammals. Biochem J. 142:401–411.
  • Krishnan B, Babu S, Walker J, Walker AB, Pappachan JM. 2013. Gastrointestinal complications of diabetes mellitus. World J Diabet. 4:51–63.
  • Laurent C, Simoneau C, Marks L, Braschi S, Champ M, Charbonnel B, Krempf M. 1995. Effect of acetate and propionate on fasting hepatic glucose production in humans. Eur J Clin Nutr. 49:484–491. eng.
  • Ley RE, Backhed F, Turnbaugh P, Lozupone CA, Knight RD, Gordon JI. 2005. Obesity alters gut microbial ecology. Proc Natl Acad Sci USA. 102:11070–11075.
  • Macfarlane GT, Macfarlane S. 2012. Bacteria, colonic fermentation, and gastrointestinal health. J AOAC Int. 95:50–60.
  • Magurran AE. 2004. An index of diversity. Measuring biological diversity. Oxford: Blackwell Science Ltd.
  • Nordic Council of Ministers. Nordic Nutrition Recommendations. 2012. [accessed 1 Nov 2017]. http://www.norden-ilibrary.org/social-issues-migration-health/nordic-nutrition-recommendations-2012_nord2014-002
  • Ohlsson B, Hoglund P, Roth B, Darwiche G. 2016. Modification of a traditional breakfast leads to increased satiety along with attenuated plasma increments of glucose, C-peptide, insulin, and glucose-dependent insulinotropic polypeptide in humans. Nutrit Res. 36:359–368.
  • Qin J, Li Y, Cai Z, Li S, Zhu J, Zhang F, Liang S, et al. 2012. A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature. 490:55–60.
  • Rios-Covian D, Ruas-Madiedo P, Margolles A, Gueimonde M, de Los Reyes-Gavilan CG, Salazar N. 2016. Intestinal short chain fatty acids and their link with diet and human health. Front Microbiol. 7:185.
  • Rodriguez-Carrio J, Lopez P, Sanchez B, Gonzalez S, Gueimonde M, Margolles A, de Los Reyes-Gavilan CG, Suarez A. 2017. Intestinal dysbiosis is associated with altered short-chain fatty acids and serum-free fatty acids in systemic lupus erythematosus. Front Immunol. 8:23.
  • Roediger WE. 1982. Utilization of nutrients by isolated epithelial cells of the rat colon. Gastroenterology. 83:424–429.
  • Sand E, Linninge C, Lozinska L, Egecioglu E, Roth B, Molin G, Westrom B, et al. 2015. Buserelin treatment to rats causes enteric neurodegeneration with moderate effects on CRF-immunoreactive neurons and Enterobacteriaceae in colon, and in acetylcholine-mediated permeability in ileum. BMC Res Notes. 8:824.
  • Santacruz A, Collado MC, Garcia-Valdes L, Segura MT, Martin-Lagos JA, Anjos T, Marti-Romero M, et al. 2010. Gut microbiota composition is associated with body weight, weight gain and biochemical parameters in pregnant women. Br J Nutrit. 104:83–92.
  • Shen W, Gaskins HR, McIntosh MK. 2014. Influence of dietary fat on intestinal microbes, inflammation, barrier function and metabolic outcomes. J Nutr Biochem. 25:270–280.
  • Slavin JL. 2005. Dietary fiber and body weight. Nutrition. 21:411–418.
  • Stenblom EL, Westrom B, Linninge C, Bonn P, Farrell M, Rehfeld JF, Montelius C. 2016. Dietary green-plant thylakoids decrease gastric emptying and gut transit, promote changes in the gut microbial flora, but does not cause steatorrhea. Nutr Metab. 13:67.
  • Subramanian S, Chait A. 2012. Hypertriglyceridemia secondary to obesity and diabetes. Biochim Biophys Acta. 1821:819–825.
  • Suez J, Korem T, Zeevi D, Zilberman-Schapira G, Thaiss CA, Maza O, Israeli D, et al. 2014. Artificial sweeteners induce glucose intolerance by altering the gut microbiota. Nature. 514:181–186.
  • Todesco T, Rao AV, Bosello O, Jenkins DJ. 1991. Propionate lowers blood glucose and alters lipid metabolism in healthy subjects. Am J Clin Nutr. 54:860–865.
  • Turnbaugh PJ, Backhed F, Fulton L, Gordon JI. 2008. Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome. Cell Host Microbe. 3:213–223.
  • Turnbaugh PJ, Ley RE, Mahowald MA, Magrini V, Mardis ER, Gordon JI. 2006. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature. 444:1027–1031.
  • Venter CS, Vorster HH, Cummings JH. 1990. Effects of dietary propionate on carbohydrate and lipid metabolism in healthy volunteers. Am J Gastroenterol. 85:549–553.
  • Vetrani C, Costabile G, Luongo D, Naviglio D, Rivellese AA, Riccardi G, Giacco R. 2016. Effects of whole-grain cereal foods on plasma short chain fatty acid concentrations in individuals with the metabolic syndrome. Nutrition. 32:217–221.
  • Walker AW, Ince J, Duncan SH, Webster LM, Holtrop G, Ze X, Brown D, et al. 2011. Dominant and diet-responsive groups of bacteria within the human colonic microbiota. ISME J. 5:220–230.
  • Wang M, Karlsson C, Olsson C, Adlerberth I, Wold AE, Strachan DP, Martricardi PM, et al. 2008. Reduced diversity in the early fecal microbiota of infants with atopic eczema. J Allergy Clin Immunol. 121:129–134.
  • Willcox DC, Scapagnini G, Willcox BJ. 2014. Healthy aging diets other than the Mediterranean: a focus on the Okinawan diet. Mech Ageing Dev. 136–137:148–162.
  • Wolever TM, Fernandes J, Rao AV. 1996. Serum acetate:propionate ratio is related to serum cholesterol in men but not women. J Nutr. 126:2790–2797.
  • Wu GD, Chen J, Hoffmann C, Bittinger K, Chen YY, Keilbaugh SA, Bewtra M, et al. 2011. Linking long-term dietary patterns with gut microbial enterotypes. Science. 334:105–108.
  • Zhao G, Liu JF, Nyman M, Jonsson JA. 2007. Determination of short-chain fatty acids in serum by hollow fiber supported liquid membrane extraction coupled with gas chromatography. J Chromatogr B Analyt Technol Biomed Life Sci. 846:202–208.
  • Zhu B, Wang X, Li L. 2010. Human gut microbiome: the second genome of human body. Protein Cell. 1:718–725.

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