Effect of blackberry juice (Rubus fruticosus L.) on anxiety-like behaviour in Wistar rats

References

• Andres-Lacueva C, Shukitt-Hale B, Galli RL, Jauregui O, Lamuela-Raventos RM, Joseph JA. 2005. Anthocyanins in aged blueberry-fed rats are found centrally and may enhance memory. Nutr Neurosci. 8:111–120.
   PubMed Web of Science ®Google Scholar
• Baronet-Jordana G. 2010. Trastornos por ansiedad. El Farmacéut Hospital. 195:12–16.
   Google Scholar
• Barros D, Amaral OB, Izquierdo I, Geracitano L, Raseira MDCB, Henriques AT, Ramirez MR. 2006. Behavioral and genoprotective effects of Vaccinium berries intake in mice. Pharmacol Biochem Behav. 84:229–234.
   PubMed Web of Science ®Google Scholar
• Bateson AN. 2002. Basic pharmacologic mechanisms involved in benzodiazepine tolerance and withdrawal. Curr Pharm Des. 8:5–21.
   PubMed Web of Science ®Google Scholar
• Bernal-Morales B, Cueto-Escobedo J, Guillén-Ruiz G, Rodríguez-Landa JF, Contreras CM. 2017. A fatty acids mixture reduces anxiety-like behaviors in infant rats mediated by GABAA receptors. Biomed Res Int. 2017:1–8.
   Google Scholar
• Borsini F. 1995. Role of the serotonergic system in the forced swimming test. Neurosci Biobehav Rev. 19:377–395.
   PubMed Web of Science ®Google Scholar
• Bouayed J. 2010. Polyphenols: a potential new strategy for the prevention and treatment of anxiety and depression. Curr Nutr Food Sci. 6:13–18.
   Google Scholar
• Campos AC, Fogaca MV, Aguiar DC, Guimaraes FS. 2013. Animal models of anxiety disorders and stress. Rev Bras Psiquiatr. 35:S101–S111.
   PubMed Web of Science ®Google Scholar
• Carlini EA. 2003. Plants and the central nervous system. Pharmacol Biochem Behav. 75:501–512.
   PubMed Web of Science ®Google Scholar
• Carobrez AP, Bertoglio LJ. 2005. Ethological and temporal analyses of anxiety-like behavior: the elevated plus-maze model 20 years on. Neurosci Biobehav Rev. 29:1193–1205.
   PubMed Web of Science ®Google Scholar
• Carro-Juárez M, Rodríguez-Landa JF, Rodríguez-Peña ML, Rovirosa-Hernández MJ, García-Orduña F. 2012. The aqueous crude extract of Montanoa frutescens produces anxiolytic-like effects similarly to diazepam in Wistar rats: involvement of GABAA receptor. J Ethnopharmacol. 143:592–598.
   PubMed Web of Science ®Google Scholar
• Chebib M, Johnston GA. 1999. The 'ABC' of GABA receptors: a brief review. Clin Exp Pharmacol Physiol. 26:937–940.
   PubMed Web of Science ®Google Scholar
• Cho MJ, Howard LR, Prior RL, Clark JR. 2004. Flavonoid glycosides and antioxidant capacity of various blackberry, blueberry and red grape genotypes determined by high‐performance liquid chromatography/mass spectrometry. J Sci Food Agric. 84:1771–1782.
   Web of Science ®Google Scholar
• Clifford MN. 2000. Anthocyanins nature, occurrence and dietary burden. J Sci Food Agric. 80:1063–1072.
   Web of Science ®Google Scholar
• Cohen H, Matar MA, Joseph Z. 2013. Animal models of post‐traumatic stress disorder. Curr Protoc Neurosci. 2013:9–45.
   Google Scholar
• Contreras CM, Martínez-Mota L, Saavedra M. 1998. Desipramine restricts estral cycle oscillations in swimming. Prog Neuropsychopharmacol Biol Psychiatry. 22:1121–1128.
   PubMed Web of Science ®Google Scholar
• Contreras CM, Rodríguez-Landa JF, García-Ríos RI, Cueto-Escobedo J, Guillen-Ruiz G, Bernal-Morales B. 2014. Myristic acid produces anxiolytic-like effects in Wistar rats in the elevated plus maze. Biomed Res Int. 2014:1–8.
   Google Scholar
• Contreras CM, Rodríguez-Landa JF, Gutiérrez-García AG, Bernal-Morales B. 2001. The lowest effective dose of fluoxetine in the forced swim test significantly affects the firing rate of lateral septal nucleus neurones in the rat. J Psychopharmacol. 15:231–236.
   PubMed Web of Science ®Google Scholar
• Contreras CM, Rodríguez-Landa JF, Gutiérrez-García AG, Mendoza-López MR, García-Ríos RI, Cueto-Escobedo J. 2011. Anxiolytic-like effects of human amniotic fluid and its fatty acids in Wistar rats. Behav Pharmacol. 22:655–662.
   PubMed Web of Science ®Google Scholar
• Dreiseitel A, Korte G, Schreier P, Oehme A, Locher S, Domani M, Hajak G, Sand PG. 2009. Berry anthocyanins and their aglycons inhibit monoamine oxidases A and B. Pharmacol Res. 59:306–311.
   PubMed Web of Science ®Google Scholar
• Engin E, Treit D. 2007. The anxiolytic-like effects of allopregnanolone vary as a function of intracerebral microinfusion site: the amygdala, medial prefrontal cortex, or hippocampus. Behav Pharmacol. 18:461–470.
   PubMed Web of Science ®Google Scholar
• Enna SJ. 2007. The GABA receptors. Totowa: Humana Press.
   Google Scholar
• Esteves-Mar AI. 2016. Efecto del consumo de un jugo de frutos rojos y uva rico en polifenoles procesado con ultrasonido en ratas Wistar con diabetes inducida.Tesis de Maestría. Universidad Veracruzana. 30–31.
   Google Scholar
• Estrada-Camarena E, Contreras CM, Saavedra M, Luna-Baltazar I, López-Rubalcava C. 2002. Participation of the lateral septal nuclei (LSN) in the antidepressant-like actions of progesterone in the forced swimming test (FST). Behav Brain Res. 134:175–183.
   PubMed Web of Science ®Google Scholar
• Fernández-Guasti A, Ferreira A, Picazo O. 2001. Diazepam, but not buspirone, induces similar anxiolytic-like actions in lactating and ovariectomized Wistar rats. Pharmacol Biochem Behav. 70:85–93.
   PubMed Web of Science ®Google Scholar
• García-Gutiérrez MS, García-Bueno B, Zoppi S, Leza JC, Manzanares J. 2012. Chronic blockade of cannabinoid CB2 receptors induces anxiolytic‐like actions associated with alterations in GABAA receptors. Br J Pharmacol. 165:951–964.
   PubMed Web of Science ®Google Scholar
• German-Ponciano LJ, Rosas-Sánchez GU, Rivadeneyra-Domínguez E, Rodríguez-Landa JF. 2018. Advances in the preclinical study of some flavonoids as potential antidepressant agents. Scientifica. 2018:1–14.
   Google Scholar
• Giusti MM, Wrolstad RE. 2001. Characterization and measurement of anthocyanins by UV‐visible spectroscopy. Curr Protoc Food Anal Chem. 2001:1–13.
   Google Scholar
• Griebel G, Sanger DJ, Perrault G. 1996. The use of the rat elevated plus-maze to discriminate between non-selective and BZ-1 (ω 1) selective, benzodiazepine receptor ligands. Psychopharmacology. 124:245–254.
   PubMed Web of Science ®Google Scholar
• Gutierres JM, Carvalho FB, Schetinger MRC, Marisco P, Agostinho P, Rodrigues M, Rubin MA, Schmatz R, da Silva CR, de P Cognato G, et al. 2014. Anthocyanins restore behavioral and biochemical changes caused by streptozotocin-induced sporadic dementia of Alzheimer's type. Life Sci. 96:7–17.
   PubMed Web of Science ®Google Scholar
• Gutiérrez-García AG, Contreras CM. 2002. Algunos aspectos etológicos de la comunicación química en ratas y ratones de laboratorio. Rev Biomed. 13:189–209.
   Google Scholar
• Hagiwara A, Yoshino H, Ichihara T, Kawabe M, Tamano S, Aoki H, Koda T, Nakamura M, Imaida K, Ito N, et al. 2002. Prevention by natural food anthocyanins, purple sweet potato color and red cabbage color, of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-associated colorectal carcinogenesis in rats initiated with 1,2-dimethylhydrazine. J Toxicol Sci. 27:57–68.
   PubMedGoogle Scholar
• Kalueff AV, Tuohimaa P. 2004. Experimental modeling of anxiety and depression. Acta Neurobiol Exp (Wars). 64:439–448.
   PubMed Web of Science ®Google Scholar
• Kalueff AV, Tuohimaa P. 2005. Contrasting grooming phenotypes in three mouse strains markedly different in anxiety and activity (129S1, BALB/c and NMRI). Behav Brain Res. 160:1.
   PubMed Web of Science ®Google Scholar
• Kamei H, Hashimoto Y, Koide T, Kojima T, Hasegawa M. 1998. Anti-tumor effect of methanol extracts from red and white wines. Cancer Biother Radiopharm. 13:447–452.
   PubMed Web of Science ®Google Scholar
• Kaminska K, Rogoz Z. 2016. The antidepressant- and anxiolytic-like effects following co-treatment with escitalopram and risperidone in rats. J Physiol Pharmacol. 67:471–480.
   PubMed Web of Science ®Google Scholar
• Kaume L, Howard LR, Devareddy L. 2012. The blackberry fruit: a review on its composition and chemistry, metabolism and bioavailability, and health benefits. J Agric Food Chem. 60:5716–5727.
   PubMed Web of Science ®Google Scholar
• Kelsey N, Hulick W, Winter A, Ross E, Linseman D. 2011. Neuroprotective effects of anthocyanins on apoptosis induced by mitochondrial oxidative stress. Nutr Neurosci. 14:249–259.
   PubMed Web of Science ®Google Scholar
• Khisti RT, Chopde CT, Jain SP. 2000. Antidepressant-like effect of the neurosteroid 3α-hydroxy-5α-pregnan-20-one in mice forced swim test. Pharmacol Biochem Behav. 67:137–143.
   PubMed Web of Science ®Google Scholar
• Kraft TFB, Schmidt BM, Yousef GG, Knight CT, Cuendet M, Kang YH, Pezzuto JM, Seigler DS, Lila MA. 2005. Chemopreventive potential of wild lowbush blueberry fruits in multiple stages of carcinogenesis. J Food Sci. 70:159–166.
   Web of Science ®Google Scholar
• Krikorian R, Shidler MD, Nash TA, Kalt W, Vinqvist-Tymchuk MR, Shukitt-Hale B, Joshep JA. 2010. Blueberry supplementation improves memory in older adults. J Agric Food Chem. 58:3996–4000.
   PubMed Web of Science ®Google Scholar
• Lakhan SE, Vieira KF. 2010. Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review. Nutr J. 9:1–14.
   PubMed Web of Science ®Google Scholar
• Lozano-Hernández R, Rodríguez-Landa JF, Hernández-Figueroa JD, Saavedra M, Ramos-Morales FR, Cruz-Sánchez JS. 2010. Antidepressant-like effects of two commercially available products of Hypericum perforatum in the forced swim test: a long-term study. J Med Plant Res. 4:131–137.
   Google Scholar
• Marder M, Paladini AC. 2002. GABA(A)-receptor ligands of flavonoid structure. Curr Top Med Chem. 2:853–867.
   PubMedGoogle Scholar
• Mexicana NO. 1999. NOM-062-ZOO-1999. Especificaciones Técnicas Para la Producción, Cuidado y Uso de Los Animales de Laboratorio.
   Google Scholar
• Nin MS, Ferri MK, Couto-Pereira NS, Souza MF, Azeredo LA, Agnes G, Gomez R, Barros HM. 2012. The effect of intranucleus accumbens administration of allopregnanolone on d and g2 GABA(A) receptor subunit mRNA expression in the hippocampus and on depressive-like and grooming behaviors in rats. Pharmacol Biochem Behav. 103:359–366.
   PubMed Web of Science ®Google Scholar
• Ohgami K, Ilieva I, Shiratori K, Koyama Y, Jin XH, Yoshida K, Kase S, Kitaichi N, Suzuki Y, Tanaka T, et al. 2005. Anti-inflammatory effects of aronia extract on rat endotoxin-induced uveitis. Invest Ophthalmol Vis Sci. 46:275–281.
   PubMed Web of Science ®Google Scholar
• Pellow S, Chopin P, File SE, Briley M. 1985. Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Methods. 14:149–167.
   PubMed Web of Science ®Google Scholar
• Pellow S, File SE. 1986. Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: a novel test of anxiety in the rat. Pharmacol Biochem Behav. 24:525–529.
   PubMed Web of Science ®Google Scholar
• Perrot-Sinal TS, Gregus A, Boudreau D, Kalynchuk LE. 2004. Sex and repeated restraint stress interact to affect cat odor-induced defensive behavior in adult rats. Brain Res. 1027:161–172.
   PubMed Web of Science ®Google Scholar
• Ramirez MR, Izquierdo I, do Carmo Bassols Raseira M, Zuanazzi JA, Barros D, Henriques AT. 2005. Effect of lyophilised Vaccinium berries on memory, anxiety and locomotion in adult rats. Pharmacol Res. 52:457–462.
   PubMed Web of Science ®Google Scholar
• Ramos A, Pereira E, Martins GC, Wehrmeister TD, Izídio GS. 2008. Integrating the open field, elevated plus maze and light/dark box to assess different types of emotional behaviors in one single trial. Behav Brain Res. 193:277–288.
   PubMed Web of Science ®Google Scholar
• Ravindran LN, Stein MB. 2010. The pharmacologic treatment of anxiety disorders: a review of progress. J Clin Psychiatry. 71:839–854.
   PubMed Web of Science ®Google Scholar
• Reddy DS, Kulkarni SK. 1996. Role of GABA-A and mitochondrial diazepam binding inhibitor receptors in the anti-stress activity of neurosteroids in mice. Psychopharmacology. 128:280–292.
   PubMed Web of Science ®Google Scholar
• Riaz M, Zia-Ul-Haq M, Ur-Rahman N, Ahmad M. 2014. Neuropharmacological effects of methanolic extracts of Rubus fruticosus L. Turk J Med Sci. 44:454–460.
   PubMed Web of Science ®Google Scholar
• Rodgers RJ, Perrault G, Sanger DJ, Griebel G. 1997. Risk assessment behaviour: evaluation of utility in the study of 5-HT-related drugs in the rat elevated plus-maze test. Pharmacol Biochem Behav. 57:817–827.
   PubMed Web of Science ®Google Scholar
• Rodríguez-Landa JF, Contreras CM, Bernal-Morales B, Gutiérrez-García AG, Saavedra M. 2007. Allopregnanolone reduces immobility in the forced swimming test and increases the firing rate of lateral septal neurons through actions on the GABAA receptor in the rat. J Psychopharmacol. 21:76–84.
   PubMed Web of Science ®Google Scholar
• Rodríguez-Landa JF, Contreras CM, García-Ríos RI. 2009. Allopregnanolone microinjected into the lateral septum or dorsal hippocampus reduces immobility in the forced swim test: participation of the GABAA receptor. Behav Pharmacol. 20:614–622.
   PubMed Web of Science ®Google Scholar
• Rodríguez-Landa JF, Contreras M. 2000. Los fármacos antidepresivos y la conducta de inmovilidad en la prueba de nado forzado: participación de los sistemas de neurotransmisión. Arch Neurociencias. 5:74–83.
   Google Scholar
• Rodríguez-Landa JF, Cueto-Escobedo J, Flores-Aguilar LÁ, Rosas-Sánchez GU, Rovirosa-Hernández MJ, García-Orduña F, Carro-Juárez M. 2018. The aqueous crude extracts of Montanoa frutescens and Montanoa grandiflora reduce immobility faster than fluoxetine through GABAA receptors in rats forced to swim. J Evid Based Integr Med. 2018:23.
   Google Scholar
• Rodríguez-Landa JF, Cueto-Escobedo J, Puga-Olguín A, Rivadeneyra-Domínguez E, Bernal-Morales B, Herrera-Huerta EV, Santos-Torres A. 2017. The phytoestrogen genistein produces similar effects as 17β-estradiol on anxiety-like behavior in rats at 12 weeks after ovariectomy. BioMed Res Int. 2017:1.
   Google Scholar
• Rodríguez-Landa JF, Hernández-Figueroa JD, Hernández-Calderón B, Saavedra M. 2009. Anxiolytic-like effect of phytoestrogen genistein in rats with long-term absence of ovarian hormones in the black and white model. Prog Neuropsychopharmacol Biol Psychiatry. 33:367–372.
   PubMed Web of Science ®Google Scholar
• Rodríguez-Landa JF, Vicente-Serna J, Rodríguez-Blanco LA, Rovirosa-Hernández MDJ, García-Orduña F, Carro-Juárez M. 2014. Montanoa frutescens and Montanoa grandiflora extracts reduce anxiety-like behavior during the metestrus-diestrus phase of the ovarian cycle in Wistar rats. Biomed Res Int. 2014:1–9.
   Google Scholar
• Rosas-Santiago FJ, Marván-Garduño ML, Lagunes-Córdoba R. 2017. Adaptation of a scale to measure coping strategies in informal primary caregivers: a case of validation with small samples. J Psychiatr Ment Health Nurs. 24:563–569.
   PubMed Web of Science ®Google Scholar
• Rosas-Gutiérrez I, Simón-Arceo K, Mercado F. 2013. Mecanismo celular y molecular de la adicción a benzodiacepinas. Salud Ment. 36:325–329.
   Google Scholar
• Russell WM, Burch RL, Hume CW. 1959. The principles of humane experimental technique. London: Methuen.
   Google Scholar
• Shipp J, Abdel-Aal ESM. 2010. Food applications and physiological effects of anthocyanins as functional food ingredients. Open Food Sci J. 4:7–22.
   Google Scholar
• Shukitt-Hale B, Lau FC, Joseph JA. 2008. Berry fruit supplementation and the aging brain. J Agric Food Chem. 56:636–641.
   PubMed Web of Science ®Google Scholar
• Singh J, Kumar A, Sharma A. 2017. Antianxiety activity guided isolation and characterization of bergenin from Caesalpinia digyna Rottler roots. J Ethnopharmacol. 195:182–187.
   PubMed Web of Science ®Google Scholar
• Singleton VL, Rossi JA. 1965. Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents. Am J Enol Vitic. 16:144–158.
   Google Scholar
• Sollozo-Dupont I, Estrada-Camarena E, Carro-Juárez M, López-Rubalcava C. 2015. GABAA/benzodiazepine receptor complex mediates the anxiolytic-like effect of Montanoa tomentosa. J Ethnopharmacol. 162:278–286.
   PubMed Web of Science ®Google Scholar
• Talavéra S, Felgines C, Texier O, Besson C, Gil-Izquierdo A, Lamaison JL, Rémésy C. 2005. Anthocyanin metabolism in rats and their distribution to digestive area, kidney, and brain. J Agric Food Chem. 53:3902–3908.
   PubMed Web of Science ®Google Scholar
• Tomić M, Ignjatović Đ, Tovilović-Kovačević G, Krstić-Milošević D, Ranković S, Popović T, Glibetić M. 2016. Reduction of anxiety-like and depression-like behaviors in rats after one month of drinking Aronia melanocarpa berry juice. Food Funct. 7:3111–3120.
   PubMed Web of Science ®Google Scholar
• Valcheva-Kuzmanova S, Eftimov M, Belcheva I, Belcheva S, Tashev R. 2016. Anti-anxiety effect of Aronia melanocarpa fruit juice administered subchronically to rats. Farmacia. 64:367–371.
   Web of Science ®Google Scholar
• Valcheva-Kuzmanova S, Zhelyazkova-Savova M. 2009. Anxiolytic-like effect of Aronia melanocarpa fruit juice in rats. Methods Find Exp Clin Pharmacol. 31:651.
   PubMedGoogle Scholar
• Vázquez-León P, Campos-Rodríguez C, Gonzalez-Pliego C, Miranda-Páez A. 2018. Differential effects of cholecystokinin (CCK-8) microinjection into the ventrolateral and dorsolateral periaqueductal gray on anxiety models in Wistar rats. Horm Behav. 106:105–111.
   PubMed Web of Science ®Google Scholar
• Viola H, Marder M, Wasowski C, Giorgi O, Paladini AC, Medina JH. 2000. 6,3′-dibromoflavone and 6-nitro-3′-bromoflavone: new additions to the 6,3′-disubstituted flavone family of high-affinity ligands of the brain benzodiazepine binding site with agonistic properties. Biochem Biophys Res Commun. 273:694–698.
   PubMed Web of Science ®Google Scholar
• Walf AA, Frye CA. 2007. The use of the elevated plus maze as an assay of anxiety-related behavior in rodents. Nat Protoc. 2:322–328.
   PubMed Web of Science ®Google Scholar
• Wang H, Hui KM, Chen Y, Xu S, Wong JT, Xue H. 2002. Structure-activity relationships of flavonoids, isolated from Scutellaria baicalensis, binding to benzodiazepine site of GABAA receptor complex. Planta Med. 68:1059–1062.
   PubMed Web of Science ®Google Scholar
• World Health Organization. 2016. Investing in treatment for depression and anxiety leads to fourfold return; [accessed 10 Aug 2018]. http://www.who.int/es/news-room/detail/13-04-2016-investing-in-treatment-for-depression-and-anxiety-leads-to-fourfold-return.
   Google Scholar
• Yadav AV, Kawale LA, Nade VS. 2008. Effect of Morus alba L. (mulberry) leaves on anxiety in mice. Indian J Pharmacol. 40:32–36.
   PubMed Web of Science ®Google Scholar
• Zanoli P, Avallone R, Baraldi M. 2000. Behavioral characterisation of the flavonoids apigenin and chrysin. Fitoterapia. 71:117–123.
   PubMed Web of Science ®Google Scholar
• Zhang LM, Yao JZ, Li Y, Li K, Chen HX, Zhang YZ, Li YF. 2012. Anxiolytic effects of flavonoids in animal models of posttraumatic stress disorder. Evid-Based Compl Alt. 2012:1.
   Web of Science ®Google Scholar
• Zhang M, Liu J, Zhou M-M, Wu H, Hou Y, Li Y-F, Yin Y, Zheng L, Cai J, Liao FF, et al. 2017. Anxiolytic effects of hippocampal neurosteroids in normal and neuropathic rats with spared nerve injury. J Neurochem. 141:137–150.
   PubMed Web of Science ®Google Scholar