Targeted upper-limb Wii-based Movement Therapy also improves lower-limb muscle activation and functional movement in chronic stroke

References

• Deloitte Access Economics. The economic impact of stroke in Australia. National Stroke Foundation. 2013:1–56.
   Google Scholar
• Bohannon RW, Andrews AW, Smith MB. Rehabilitaion goals of patients with hemiplegia. Int J Rehabil Res. 1988;11:181–183.
   Web of Science ®Google Scholar
• Stoller O, de Bruin ED, Schuster-Amft C, et al. Cardiovascular rehabilitation soon after stroke using feedback-controlled robotics-assisted treadmill exercise: study protocol of a randomised controlled pilot trial. Trials. 2013;14:304.
   PubMed Web of Science ®Google Scholar
• Jorgensen HS, Nakayama H, Raaschou HO, et al. Recovery of walking function in stroke patients: the Copenhagen stroke study. Arch Phys Med Rehabil. 1995;76:27–32.
   PubMed Web of Science ®Google Scholar
• Ada L, Dean CM, Lindley R, et al. Improving community ambulation after stroke: the AMBULATE Trial. BMC Neurol. 2009;9:8.
   PubMed Web of Science ®Google Scholar
• Mayo NE, Wood-Dauphinee S, Cote R, et al. Activity, participation, and quality of life 6 months poststroke. Arch Phys Med Rehabil. 2002;83:1035–1042.
   PubMed Web of Science ®Google Scholar
• Blennerhassett JM, Dite W, Ramage ER, et al. Changes in balance and walking from stroke rehabilitation to the community: a follow-up observational study. Arch Phys Med Rehabil. 2012;93:1782–1787.
   PubMed Web of Science ®Google Scholar
• Lee CD, Folsom AR, Blair SN. Physical activity and stroke risk: a meta-analysis. Stroke. 2003;34:2475–2481.
   PubMed Web of Science ®Google Scholar
• Chen CL, Chen HC, Tang SF, et al. Gait performance with compensatory adaptations in stroke patients with different degrees of motor recovery. Am J Phys Med Rehabil. 2003;82:925–935.
   PubMed Web of Science ®Google Scholar
• Chen G, Patten C, Kothari DH, et al. Gait differences between individuals with post-stroke hemiparesis and non-disabled controls at matched speeds. Gait Posture. 2005;22:51–56.
   PubMed Web of Science ®Google Scholar
• Kim CM, Eng JJ. Symmetry in vertical ground reaction force is accompanied by symmetry in temporal but not distance variables of gait in persons with stroke. Gait Posture. 2003;18:23–28.
   PubMed Web of Science ®Google Scholar
• Hsu AL, Tang PF, Jan MH. Analysis of impairments influencing gait velocity and asymmetry of hemiplegic patients after mild to moderate stroke. Arch Phys Med Rehabil. 2003;84:1185–1193.
   PubMed Web of Science ®Google Scholar
• Patterson KK, Parafianowicz I, Danells CJ, et al. Gait asymmetry in community-ambulating stroke survivors. Arch Phys Med Rehabil. 2008;89:304–310.
   PubMed Web of Science ®Google Scholar
• Luft A, Macko R, Forrester L, et al. Post-stroke exercise rehabilitation: what we know about retraining the motor system and how it may apply to retraining the heart. Clev Clin J Med. 2008;75:S83–S86.
   PubMedGoogle Scholar
• van de Port IG, Kwakkel G, van Wijk I, et al. Susceptibility to deterioration of mobility long-term after stroke: a prospective cohort study. Stroke. 2006;37:167–171.
   PubMed Web of Science ®Google Scholar
• Ivey FM, Hafer-Macko CE, Macko RF. Exercise rehabilitation after stroke. NeuroRx. 2006;3:439–450.
   PubMedGoogle Scholar
• Michael K, Macko RF. Ambulatory activity intensity profiles, fitness, and fatigue in chronic stroke. Top Stroke Rehabil. 2007;14:5–12.
   PubMed Web of Science ®Google Scholar
• Lairamore C, Garrison MK, Bandy W, et al. Comparison of tibialis anterior muscle electromyography, ankle angle, and velocity when individuals post stroke walk with different orthoses. Prosthet Orthot. 2011;35:402–410.
   PubMed Web of Science ®Google Scholar
• Stewart JD. Foot drop: where, why and what to do? Pract Neurol. 2008;8:158–169.
   PubMedGoogle Scholar
• Wagenaar RC, Beek WJ. Hemiplegic gait: a kinematic analysis using walking speed as a basis. J Biomech. 1992;25:1007–1015.
   PubMed Web of Science ®Google Scholar
• Olney SJ, Richards C. Hemiparetic gait following stroke. Part I: characteristics. Gait Posture. 1995;4:136–148.
   Google Scholar
• Forster A, Young J. Incidence and consequences of falls due to stroke: a systematic inquiry. BMJ. 1995;311:83–86.
   PubMed Web of Science ®Google Scholar
• de Wit DC, Buurke JH, Nijlant JM, et al. The effect of an ankle-foot orthosis on walking ability in chronic stroke patients: a randomized controlled trial. Clin Rehabil. 2004;18:550–557.
   PubMed Web of Science ®Google Scholar
• Teasell RW, McRae MP, Foley N, et al. Physical and functional correlations of ankle-foot orthosis use in the rehabilitation of stroke patients. Arch Phys Med Rehabil. 2001;82:1047–1049.
   PubMed Web of Science ®Google Scholar
• Cattaneo D, Marazzini F, Crippa A, et al. Do static or dynamic AFOs improve balance? Clin Rehabil. 2002;16:894–899.
   PubMed Web of Science ®Google Scholar
• Chen CL, Yeung KT, Wang CH, et al. Anterior ankle-foot orthosis effects on postural stability in hemiplegic patients. Arch Phys Med Rehabil. 1999;80:1587–1592.
   PubMed Web of Science ®Google Scholar
• Simons CD, van Asseldonk EH, van der Kooij H, et al. Ankle-foot orthoses in stroke: effects on functional balance, weight-bearing asymmetry and the contribution of each lower limb to balance control. Clin Biomech. 2009;24:769–775.
   PubMed Web of Science ®Google Scholar
• Gresham GE, Duncan PW, Stason WB. Post-stroke rehabilitation. Philadelphia, PA: Diane Publishing Co; 1997. p. 1–248.
   Google Scholar
• Kwakkel G, Kollen BJ, Wagenaar RC. Long term effects of intensity of upper and lower limb training after stroke: a randomised trial. J Neurol Neurosurg Psychiatr. 2002;72:473–479.
   PubMed Web of Science ®Google Scholar
• Collaborative systematic review of the randomised trials of organised inpatient (stroke unit) care after stroke. Stroke Unit Trialists' Collaboration. BMJ. 1997;314:1151–1159.
   PubMedGoogle Scholar
• Pollock A, Baer G, Campbell P, et al. Physical rehabilitation approaches for the recovery of function and mobility following stroke. Cochrane Database Syst Rev. 2014;4:CD001920.
   PubMed Web of Science ®Google Scholar
• Wolf SL, Lecraw DE, Barton LA, et al. Forced use of hemiplegic upper extremities to reverse the effect of learned nonuse among chronic stroke and head-injured patients. Exp Neurol. 1989;104:125–132.
   PubMed Web of Science ®Google Scholar
• French B, Thomas LH, Leathley MJ, et al. Repetitive task training for improving functional ability after stroke. Cochrane Database Syst Rev. 2007;4:CD006073.
   PubMed Web of Science ®Google Scholar
• Uswatte G, Taub E, Morris D, et al. The motor activity log-28: assessing daily use of the hemiparetic arm after stroke. Neurology. 2006;67:1189–1194.
   PubMed Web of Science ®Google Scholar
• McNulty PA, Thompson-Butel AG, Faux SG, et al. The efficacy of Wii-based Movement Therapy for upper limb rehabilitation in the chronic poststroke period: a randomized controlled trial. Int J Stroke. 2015;10:1253–1260.
   PubMed Web of Science ®Google Scholar
• McNulty PA, Thompson-Butel AG, Shiner CT, et al. Wii-based Movement Therapy benefits stroke patients with low and very low movement ability. Soc Care Neurodisabil. 2013;4:114–123.
   Google Scholar
• Trinh T, Scheuer SE, Thompson-Butel AG, et al. Cardiovascular fitness is improved post-stroke with upper-limb Wii-based Movement Therapy but not dose-matched Constraint Therapy. Top Stroke Rehabil. 2016;23:208–216.
   PubMed Web of Science ®Google Scholar
• Thompson-Butel AG, Lin GG, Shiner CT, et al. Two common tests of dexterity can stratify upper limb motor function after stroke. Neurorehabil Neural Repair. 2014;28:788–796.
   PubMed Web of Science ®Google Scholar
• Shiner CT, Byblow WD, McNulty PA. Bilateral priming before wii-based movement therapy enhances upper limb rehabilitation and its retention after stroke: a case-controlled study. Neurorehabil Neural Repair. 2014;28:828–838.
   PubMed Web of Science ®Google Scholar
• McNulty PA. Games for rehabilitation: Wii-based movement therapy improves poststroke movement ability. Games Health J. 2012;1:384–387.
   PubMed Web of Science ®Google Scholar
• Mouawad MR, Doust CG, Max MD, et al. Wii-based movement therapy to promote improved upper extremity function post-stroke: a pilot study. J Rehabil Med. 2011;43:527–533.
   PubMed Web of Science ®Google Scholar
• Isakov E, Keren O, Benjuya N. Trans-tibial amputee gait: time-distance parameters and EMG activity. Prosthet Orthot Int. 2000;24:216–220.
   PubMed Web of Science ®Google Scholar
• Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Statist Soc B. 1995;57:289–300.
   Web of Science ®Google Scholar
• Mudge S, Barber PA, Stott NS. Circuit-based rehabilitation improves gait endurance but not usual walking activity in chronic stroke: a randomized controlled trial. Arch Phys Med Rehabil. 2009;90:1989–1996.
   PubMed Web of Science ®Google Scholar
• Riddle DL, Stratford PW. Interpreting validity indexes for diagnostic tests: an illustration using the Berg balance test. Phys Ther. 1999;79:939–948.
   PubMed Web of Science ®Google Scholar
• Casanova C, Celli BR, Barria P, et al. The 6-min walk distance in healthy subjects: reference standards from seven countries. Eur Respir J. 2011;37:150–156.
   PubMed Web of Science ®Google Scholar
• Belavy DL, Richardson CA, Wilson SJ, et al. Tonic-to-phasic shift of lumbo-pelvic muscle activity during 8 weeks of bed rest and 6-months follow up. J Appl Physiol. 2007;103:48–54.
   PubMed Web of Science ®Google Scholar
• Hendrickson J, Patterson KK, Inness EL, et al. Relationship between asymmetry of quiet standing balance control and walking post-stroke. Gait Posture. 2014;39:177–181.
   PubMed Web of Science ®Google Scholar
• Zhang L, Li P, Mao Z, et al. Changes in motor function in the unaffected hand of stroke patients should not be ignored. Neural Regen Res. 2014;9:1323–1328.
   PubMed Web of Science ®Google Scholar
• Kitsos GH, Hubbard IJ, Kitsos AR, et al. The ipsilesional upper limb can be affected following stroke. Sci World J. 2013;2013:1–7.
   Web of Science ®Google Scholar
• Wetter S, Poole JL, Haaland KY. Functional implications of ipsilesional motor deficits after unilateral stroke. Arch Phys Med Rehabil. 2005;86:776–781.
   PubMed Web of Science ®Google Scholar
• Johansen-Berg H, Rushworth MF, Bogdanovic MD, et al. The role of ipsilateral premotor cortex in hand movement after stroke. Proc Natl Acad Sci USA. 2002;99:14518–14523.
   PubMed Web of Science ®Google Scholar
• Bowden JL, Taylor JL, McNulty PA. Voluntary activation is reduced in both the more- and less-affected upper limbs after unilateral stroke. Front Neurol. 2014;5:239.
   PubMed Web of Science ®Google Scholar
• Talelli P, Greenwood RJ, Rothwell JC. Arm function after stroke: neurophysiological correlates and recovery mechanisms assessed by transcranial magnetic stimulation. Clin Neurophys. 2006;117:1641–1659.
   PubMed Web of Science ®Google Scholar
• Reisman DS, Wityk R, Silver K, et al. Locomotor adaptation on a split-belt treadmill can improve walking symmetry post-stroke. Brain. 2007;130:1861–1872.
   PubMed Web of Science ®Google Scholar
• Begg RK, Tirosh O, Said CM, et al. Gait training with real-time augmented toe-ground clearance information decreases tripping risk in older adults and a person with chronic stroke. Front Hum Neurosci. 2014;8:243.
   PubMed Web of Science ®Google Scholar
• Mori S. Discharge patterns of soleus motor units with associated changes in force exerted by foot during quiet stance in man. J Neurophysiol. 1973;36:458–471.
   PubMed Web of Science ®Google Scholar
• Rainoldi A, Melchiorri G, Caruso I. A method for positioning electrodes during surface EMG recordings in lower limb muscles. J Neurosci Methods. 2004;134:37–43.
   PubMed Web of Science ®Google Scholar
• Wevers LE, Kwakkel G, van de Port IG. Is outdoor use of the six-minute walk test with a global positioning system in stroke patients' own neighbourhoods reproducible and valid? J Rehabil Med. 2011;43:1027–1031.
   PubMed Web of Science ®Google Scholar
• Patterson SL, Forrester LW, Rodgers MM, et al. Determinants of walking function after stroke: differences by deficit severity. Arch Phys Med Rehabil. 2007;88:115–119.
   PubMed Web of Science ®Google Scholar
• Mansfield A, Wong JS, McIlroy WE, et al. Do measures of reactive balance control predict falls in people with stroke returning to the community? Physiotherapy. 2015;101:373–380.
   PubMed Web of Science ®Google Scholar
• Sherrington C, Lord SR, Finch CF. Physical activity interventions to prevent falls among older people: update of the evidence. J Sci Med Sport. 2004;7:43–51.
   PubMedGoogle Scholar
• Billinger SA, Arena R, Bernhardt J, et al. Physical activity and exercise recommendations for stroke survivors: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2014;45:2532–2553.
   PubMed Web of Science ®Google Scholar
• Faux S. A 10 year audit of recurrent admissions to rehabilitation following incident stroke. Int J Stroke. 2011;6:9.
   Google Scholar
• Young J. Is stroke better managed in the community? Community care allows patients to reach their full potential. BMJ. 1994;309:1356–1357.
   PubMed Web of Science ®Google Scholar
• Forster A, Mellish K, Farrin A, et al. Development and evaluation of tools and an intervention to improve patient- and carer-centred outcomes in longer-term stroke care and exploration of adjustment post stroke: the LoTS care research programme. Program Grants Appl Res. 2014;2:1–262.
   Google Scholar
• Wade DT, Wood VA, Heller A, et al. Walking after stroke. Measurement and recovery over the first 3 months. Scand J Rehabil Med. 1987;19:25–30.
   PubMedGoogle Scholar
• Dobkin BH. Clinical practice. Rehabilitation after stroke. N Engl J Med. 2005;352:1677–1684.
   PubMed Web of Science ®Google Scholar
• Kaste M, Fogelholm R, Rissanen A. Economic burden of stroke and the evaluation of new therapies. Public Health. 1998;112:103–112.
   PubMed Web of Science ®Google Scholar