Early physical rehabilitation therapy between 24 and 48 h following acute ischemic stroke onset: a randomized controlled trial

References

• Li WA, Geng X, Ding Y. Stroke is a global epidemic: new developments in clinical and translational cerebrovascular diseases research. Neurol Res. 2017;39(6):475–476.
   PubMed Web of Science ®Google Scholar
• Liu L, Wang D, Wong KS, et al. Stroke and stroke care in China: huge burden, significant workload, and a national priority. Stroke. 2011;42(12):3651–3654.
   PubMed Web of Science ®Google Scholar
• Zulian G, Donisi V, Secco G, et al. How are caseload and service utilisation of psychiatric services influenced by distance? Soc Psychiatry Psychiatr Epidemiol. 2011;46(9):881–891.
   PubMed Web of Science ®Google Scholar
• Gittler M, Davis AM. Guidelines for adult stroke rehabilitation and recovery. Jama. 2018;319(8):820–821.
   PubMed Web of Science ®Google Scholar
• Bernhardt J, English C, Johnson L, et al. Early mobilization after stroke: early adoption but limited evidence. Stroke. 2015;46(4):1141–1146.
   PubMed Web of Science ®Google Scholar
• Reuter B, Gumbinger C, Sauer T, and Stroke Working Group of Baden-Wuerttemberg, et al. Access, timing and frequency of very early stroke rehabilitation – insights from the Baden-Wuerttemberg stroke registry. BMC Neurol. 2016;16(1):222.
   PubMedGoogle Scholar
• Sundseth A, Thommessen B, Ronning OM. Early mobilization after acute stroke. J Stroke Cerebrovasc Dis. 2014;23(3):496–499.
   PubMed Web of Science ®Google Scholar
• Sundseth A, Thommessen B, Ronning OM. Outcome after mobilization within 24 hours of acute stroke: a randomized controlled trial. Stroke. 2012;43(9):2389–2394.
   PubMed Web of Science ®Google Scholar
• Efficacy and safety of very early mobilisation within 24 h of stroke onset (AVERT): a randomised controlled trial. Lancet (London, England). 2015;386:46–55.
   PubMed Web of Science ®Google Scholar
• Bernhardt J, Churilov L, Ellery F, et al. Prespecified dose-response analysis for A Very Early Rehabilitation Trial (AVERT). Neurology. 2016;86(23):2138–2145.
   PubMed Web of Science ®Google Scholar
• Yelnik AP, Quintaine V, Andriantsifanetra C, et al.; on behalf of the AMOBES Group. AMOBES (Active Mobility Very Early After Stroke): a randomized controlled trial. Stroke. 2017;48(2):400–405.
   PubMed Web of Science ®Google Scholar
• Dromerick AW, Lang CE, Birkenmeier RL, et al. Very early constraint-induced movement during stroke rehabilitation (VECTORS): a single-center RCT. Neurology. 2009;73(3):195–201.
   PubMed Web of Science ®Google Scholar
• Powers WJ, Rabinstein AA, Ackerson T, et al.; American Heart Association Stroke Council. 2018 Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2018;49(3):e46–e110.
   PubMed Web of Science ®Google Scholar
• Carvalho LB, Kramer S, Borschmann K, et al. Cerebral haemodynamics with head position changes post-ischaemic stroke: a systematic review and meta-analysis. J Cereb Blood Flow Metab. 2020;40(10):1917–1933.
   Web of Science ®Google Scholar
• Liu N, Cadilhac DA, Andrew NE, et al. Randomized controlled trial of early rehabilitation after intracerebral hemorrhage stroke: difference in outcomes within 6 months of stroke. Stroke. 2014;45(12):3502–3507.
   PubMed Web of Science ®Google Scholar
• Li F, Pendy JT Jr, Ding JN, et al. Exercise rehabilitation immediately following ischemic stroke exacerbates inflammatory injury. Neurol Res. 2017;39(6):530–537.
   PubMed Web of Science ®Google Scholar
• Shen J, Huber M, Zhao EY, et al. Early rehabilitation aggravates brain damage after stroke via enhanced activation of nicotinamide adenine dinucleotide phosphate oxidase (NOX). Brain Res. 2016;1648:266–276.
   PubMed Web of Science ®Google Scholar
• Li F, Shi W, Zhao EY, et al. Enhanced apoptosis from early physical exercise rehabilitation following ischemic stroke. J Neurosci Res. 2017;95(4):1017–1024.
   PubMed Web of Science ®Google Scholar
• Komitova M, Mattsson B, Johansson BB, et al. Enriched environment increases neural stem/progenitor cell proliferation and neurogenesis in the subventricular zone of stroke-lesioned adult rats. Stroke. 2005;36(6):1278–1282.
   PubMed Web of Science ®Google Scholar
• Zhang P, Yu H, Zhou N, et al. Early exercise improves cerebral blood flow through increased angiogenesis in experimental stroke rat model. J Neuroeng Rehabil. 2013;10:43.
   PubMed Web of Science ®Google Scholar
• Zheng HQ, Zhang LY, Luo J, et al. Physical exercise promotes recovery of neurological function after ischemic stroke in rats. Int J Mol Sci. 2014;15(6):10974–10988.
   PubMed Web of Science ®Google Scholar
• Zhang P, Zhang Q, Pu H, et al. Very early-initiated physical rehabilitation protects against ischemic brain injury. Front Biosci (Elite Ed). 2012;4:2476–2489.
   PubMedGoogle Scholar
• Zhang Y, Zhang P, Shen X, et al. Early exercise protects the blood-brain barrier from ischemic brain injury via the regulation of MMP-9 and occludin in rats. IJMS. 2013;14(6):11096–11112.
   Google Scholar
• Biernaskie J, Chernenko G, Corbett D. Efficacy of rehabilitative experience declines with time after focal ischemic brain injury. J Neurosci. 2004;24(5):1245–1254.
   PubMed Web of Science ®Google Scholar
• Stroemer RP, Kent TA, Hulsebosch CE. Neocortical neural sprouting, synaptogenesis, and behavioral recovery after neocortical infarction in rats. Stroke. 1995;26(11):2135–2144.
   PubMed Web of Science ®Google Scholar
• Carmichael ST. Cellular and molecular mechanisms of neural repair after stroke: making waves. Ann Neurol. 2006;59(5):735–742.
   PubMed Web of Science ®Google Scholar
• Kwakkel G, Winters C, van Wegen EE, et al.; on behalf of the EXPLICIT-Stroke Consortium. Effects of unilateral upper limb training in two distinct prognostic groups early after stroke: the EXPLICIT-stroke randomized clinical trial. Neurorehabil Neural Repair. 2016;30(9):804–816.
   PubMed Web of Science ®Google Scholar
• Hatem SM, Saussez G, Della Faille M, et al. Rehabilitation of motor function after stroke: a multiple systematic review focused on techniques to stimulate upper extremity recovery. Front Hum Neurosci. 2016;10:442.
   PubMed Web of Science ®Google Scholar
• Lee KB, Lim SH, Kim KH, et al. Six-month functional recovery of stroke patients: a multi-time-point study. Int J Rehabil Res. 2015;38(2):173–180.
   PubMed Web of Science ®Google Scholar
• Hendricks HT, van Limbeek J, Geurts AC, et al. Motor recovery after stroke: a systematic review of the literature. Arch Phys Med Rehabil. 2002;83(11):1629–1637.
   PubMed Web of Science ®Google Scholar
• Hakkennes S, Hill KD, Brock K, et al. Accessing inpatient rehabilitation after acute severe stroke: age, mobility, prestroke function and hospital unit are associated with discharge to inpatient rehabilitation. Int J Rehabil Res. 2012;35(4):323–329.
   PubMed Web of Science ®Google Scholar
• Pollock A, Baer G, Campbell P, et al. Physical rehabilitation approaches for the recovery of function and mobility following stroke. Cochrane Database Syst Rev. 2014;(4):CD001920.
   PubMedGoogle Scholar
• Hakkennes SJ, Brock K, Hill KD. Selection for inpatient rehabilitation after acute stroke: a systematic review of the literature. Arch Phys Med Rehabil. 2011;92(12):2057–2070.
   PubMed Web of Science ®Google Scholar