2,046
Views
1
CrossRef citations to date
0
Altmetric
Research Articles

Replacing sitting with light-intensity physical activity throughout the day versus 1 bout of vigorous-intensity exercise: similar cardiometabolic health effects in multiple sclerosis. A randomised cross-over study

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon & ORCID Icon
Pages 3293-3302 | Received 12 Apr 2022, Accepted 04 Sep 2022, Published online: 03 Oct 2022

References

  • Tullman MJ. Overview of the epidemiology, diagnosis, and disease progression associated with multiple sclerosis. Am J Manag Care. 2013;19(2 Suppl):S15–S20.
  • Noseworthy JH, Lucchinetti C, Rodriguez M, et al. Multiple sclerosis. N Engl J Med. 2000;343(13):938–952.
  • Asano M, Duquette P, Andersen R, et al. Exercise barriers and preferences among women and men with multiple sclerosis. Disabil Rehabil. 2013;35(5):353–361.
  • Motl RW. Physical activity and irreversible disability in multiple sclerosis. Exerc Sport Sci Rev. 2010;38(4):186–191.
  • Klaren RE, Motl RW, Dlugonski D, et al. Objectively quantified physical activity in persons with multiple sclerosis. Arch Phys Med Rehabil. 2013;94(12):2342–2348.
  • Veldhuijzen van Zanten JJ, Pilutti LA, Duda JL, et al. Sedentary behaviour in people with multiple sclerosis: is it time to stand up against MS? Mult Scler. 2016;22(10):1250–1256.
  • Tremblay MS, Aubert S, Barnes JD, et al. Sedentary behavior research network (SBRN) - Terminology consensus project process and outcome. Int J Behav Nutr Phys Act. 2017;14(1):75.
  • WHO Guidelines Approved by the Guidelines Review Committee. WHO guidelines on physical activity and sedentary behaviour. Geneva: World Health Organization; 2020.
  • Wang Y, Bos SD, Harbo HF, et al. Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors. Mult Scler. 2016;22(14):1783–1793.
  • Oliveira SR, Simão AN, Kallaur AP, et al. Disability in patients with multiple sclerosis: influence of insulin resistance, adiposity, and oxidative stress. Nutrition. 2014;30(3):268–273.
  • Pagano G, Cavallo-Perin P, Cassader M, et al. An in vivo and in vitro study of the mechanism of prednisone-induced insulin resistance in healthy subjects. J Clin Invest. 1983;72(5):1814–1820.
  • Keytsman C, Eijnde BO, Hansen D, et al. Elevated cardiovascular risk factors in multiple sclerosis. Mult Scler Relat Disord. 2017;17:220–223.
  • Hubbard EA, Motl RW, Fernhall B. Sedentary behavior and blood pressure in patients with multiple sclerosis. Int J MS Care. 2018;20(1):1–8.
  • Wens I, Dalgas U, Deckx N, et al. Does multiple sclerosis affect glucose tolerance? Mult Scler. 2014;20(9):1273–1276.
  • Wens I, Dalgas U, Stenager E, et al. Risk factors related to cardiovascular diseases and the metabolic syndrome in multiple sclerosis – a systematic review. Mult Scler. 2013;19(12):1556–1564.
  • Marrie RA, Rudick R, Horwitz R, et al. Vascular comorbidity is associated with more rapid disability progression in multiple sclerosis. Neurology. 2010;74(13):1041–1047.
  • Weinstock-Guttman B, Zivadinov R, Mahfooz N, et al. Serum lipid profiles are associated with disability and MRI outcomes in multiple sclerosis. J Neuroinflammation. 2011;8(1):127.
  • Ewanchuk BW, Gharagozloo M, Peelen E, et al. Exploring the role of physical activity and exercise for managing vascular comorbidities in people with multiple sclerosis: a scoping review. Mult Scler Relat Disord. 2018;26:19–32.
  • Coulter EH, Bond S, Dalgas U, et al. The effectiveness of interventions targeting physical activity and/or sedentary behaviour in people with multiple sclerosis: a systematic review. Disabil Rehabil. 2020;42(5):594–612.
  • Casey B, Coote S, Hayes S, et al. Changing physical activity behavior in people with multiple sclerosis: a systematic review and meta-analysis. Arch Phys Med Rehabil. 2018;99(10):2059–2075.
  • Mehrabani G, Aminian S, Norton S, et al. Preliminary efficacy of the “SitLess with MS” intervention for changing sedentary behaviour, symptoms, and physical performance in multiple sclerosis. Disabil Rehabil. 2021:1–8.
  • Baird JF, Sasaki JE, Sandroff BM, et al. Feasibility of “sit less, move more”: an intervention for reducing sedentary behavior among African Americans with MS. Mult Scler J Exp Transl Clin. 2020;6(2):2055217320932341.
  • Ryan JM, Fortune J, Stennett A, et al. Safety, feasibility, acceptability and effects of a behaviour-change intervention to change physical activity behaviour among people with multiple sclerosis: results from the iStep-MS randomised controlled trial. Mult Scler. 2020;26(14):1907–1918.
  • Duvivier B, Schaper NC, Koster A, et al. Benefits of substituting sitting with standing and walking in free-living conditions for cardiometabolic risk markers, cognition and mood in overweight adults. Front Physiol. 2017;8:353.
  • Duvivier BM, Schaper NC, Bremers MA, et al. Minimal intensity physical activity (standing and walking) of longer duration improves insulin action and plasma lipids more than shorter periods of moderate to vigorous exercise (cycling) in sedentary subjects when energy expenditure is comparable. PLOS One. 2013;8(2):e55542.
  • Duvivier BM, Schaper NC, Hesselink MK, et al. Breaking sitting with light activities vs structured exercise: a randomised crossover study demonstrating benefits for glycaemic control and insulin sensitivity in type 2 diabetes. Diabetologia. 2017;60(3):490–498.
  • Remie CME, Janssens GE, Bilet L, et al. Sitting less elicits metabolic responses similar to exercise and enhances insulin sensitivity in postmenopausal women. Diabetologia. 2021;64(12):2817–2828.
  • Thompson AJ, Banwell BL, Barkhof F, et al. Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria. Lancet Neurol. 2018;17(2):162–173.
  • Feldhege F, Mau-Moeller A, Lindner T, et al. Accuracy of a custom physical activity and knee angle measurement sensor system for patients with neuromuscular disorders and gait abnormalities. Sensors. 2015;15(5):10734–10752.
  • Savelberg H, Berendsen, BA, Granat M. An ActivPAL cycling algorithm: validity and relevance [conference presentation abstract]. Special Interest Group: J. Assessment and Methodologies in Behavioral Nutrition and Physical Activity. ISBNPA XChange Initiative International Society of Behavioral Nutrition and Physical Activity; 2021.
  • Courtney JB, Nuss K, Lyden K, et al. Comparing the activPAL software’s primary time in bed algorithm against self-report and van der berg’s algorithm. Meas Phys Educ Exerc Sci. 2021;25(3):212–226.
  • Tudor-Locke C, Sisson SB, Collova T, et al. Pedometer-determined step count guidelines for classifying walking intensity in a young ostensibly healthy population. Can J Appl Physiol. 2005;30(6):666–676.
  • Ryan CG, Grant PM, Tigbe WW, et al. The validity and reliability of a novel activity monitor as a measure of walking. Br J Sports Med. 2006;40(9):779–784.
  • Lyden K, Keadle SK, Staudenmayer J, et al. The activPALTM accurately classifies activity intensity categories in healthy adults. Med Sci Sports Exerc. 2017 May;49(5):1022–1028.
  • Lucernoni KM, Kim S, Byrnes WC. ActivPAL accuracy in determining metabolic rate during walking, running and cycling. J Sports Sci. 2021;20:1–9.
  • Pettitt R, Pettitt C, Cabrera C, et al. A theoretical method of using heart rate to estimate energy expenditure during exercise. Int J Sports Sci Coach. 2007;2(3):319–327.
  • Cleland BT, Ingraham BA, Pitluck MC, et al. Reliability and validity of ratings of perceived exertion in persons with multiple sclerosis. Arch Phys Med Rehabil. 2016;97(6):974–982.
  • Matthews JN, Altman DG, Campbell MJ, et al. Analysis of serial measurements in medical research. BMJ. 1990;300(6719):230–235.
  • Matsuda M, DeFronzo RA. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care. 1999;22(9):1462–1470.
  • Abdul-Ghani MA, Matsuda M, Balas B, et al. Muscle and liver insulin resistance indexes derived from the oral glucose tolerance test. Diabetes Care. 2007;30(1):89–94.
  • O'Donovan SD, Lenz M, Goossens GH, et al. Improved quantification of muscle insulin sensitivity using oral glucose tolerance test data: the MISI calculator. Sci Rep. 2019;9(1):9388.
  • Heine M, Hoogervorst ELJ, Hacking HGA, et al. Validity of maximal exercise testing in people with multiple sclerosis and low to moderate levels of disability. Phys Ther. 2014;94(8):1168–1175.
  • Langeskov-Christensen M, Langeskov-Christensen D, Overgaard K, et al. Validity and reliability of VO2-max measurements in persons with multiple sclerosis. J Neurol Sci. 2014;342(1–2):79–87.
  • Bergouignan A, Latouche C, Heywood S, et al. Frequent interruptions of sedentary time modulates contraction- and insulin-stimulated glucose uptake pathways in muscle: ancillary analysis from randomized clinical trials. Sci Rep. 2016;6:32044.
  • Bey L, Hamilton MT. Suppression of skeletal muscle lipoprotein lipase activity during physical inactivity: a molecular reason to maintain daily low-intensity activity. J Physiol. 2003;551(2):673–682.
  • Lang PB, Latin RW, Berg KE, et al. The accuracy of the ACSM cycle ergometry equation. Med Sci Sports Exerc. 1992;24(2):272–276.
  • Achten J, Jeukendrup AE. Maximal fat oxidation during exercise in trained men. Int J Sports Med. 2003;24(8):603–608.
  • Agiovlasitis S, Motl RW. Step-rate thresholds for physical activity intensity in persons with multiple sclerosis. Adapt Phys Activ Q. 2014;31(1):4–18.
  • Way KL, Sultana RN, Sabag A, et al. The effect of high intensity interval training versus moderate intensity continuous training on arterial stiffness and 24 h blood pressure responses: a systematic review and meta-analysis. J Sci Med Sport. 2019 ;22(4):385–391.
  • Dempsey PC, Sacre JW, Larsen RN, et al. Interrupting prolonged sitting with brief bouts of light walking or simple resistance activities reduces resting blood pressure and plasma noradrenaline in type 2 diabetes. J Hypertens. 2016;34(12):2376–2382.
  • Ranadive SM, Yan H, Weikert M, et al. Vascular dysfunction and physical activity in multiple sclerosis. Med Sci Sports Exerc. 2012;44(2):238–243.
  • Kasapis C, Thompson PD. The effects of physical activity on serum C-reactive protein and inflammatory markers: a systematic review. J Am Coll Cardiol. 2005;45(10):1563–1569.
  • Berendsen BA, Hendriks MR, Meijer K, et al. Which activity monitor to use? Validity, reproducibility and user friendliness of three activity monitors. BMC Public Health. 2014;14:749.
  • Kozey-Keadle S, Libertine A, Lyden K, et al. Validation of wearable monitors for assessing sedentary behavior. Med Sci Sports Exerc. 2011;43(8):1561–1567.
  • Weber CM, Clyne AM. Sex differences in the blood-brain barrier and neurodegenerative diseases. APL Bioeng. 2021;5(1):011509.