368
Views
1
CrossRef citations to date
0
Altmetric
Review

What are the best parameters of low-level laser therapy to reduce pain intensity and improve mandibular function in orofacial pain? A systematic review and meta-analysis

ORCID Icon, , ORCID Icon, , , & show all
Pages 3219-3237 | Received 05 Apr 2022, Accepted 18 Sep 2022, Published online: 20 Oct 2022

References

  • Benoliel R, May A, Svensson P. International Classification of Orofacial Pain (ICOP). Cephalalgia. 2020;40(2):129–221.
  • Gilkey SJ, Plaza-Villegas F. Evaluation and management of orofacial pain. JAAPA. 2017;30(5):16–22.
  • Egbuniwe O, Renton T. Pain paper 2b: classification of orofacial pain and an update on assessment and diagnosis. Dent Update. 2015;42(4):336–345.
  • Renton T, Durham J, Aggarwal VR. The classification and differential diagnosis of orofacial pain. Expert Rev Neurother. 2012;12(5):569–576.
  • Cooper BC. An orofacial pain specialty: an asset or liability to dentistry and the public. Cranio. 2019;37(6):344–346.
  • Armijo-Olivo S, Pitance L, Singh V, et al. Effectiveness of manual therapy and therapeutic exercise for temporomandibular disorders: systematic review and meta-analysis. Phys Ther. 2016;96(1):9–25.
  • Calixtre L, Moreira R, Franchini G, et al. Manual therapy for the management of pain and limited range of motion in subjects with signs and symptoms of temporomandibular disorder: a systematic review of randomised controlled trials. J Oral Rehabil. 2015;42(11):847–861.
  • Fougeront N, Fleiter B. Temporomandibular disorder and comorbid neck pain: facts and hypotheses regarding pain-induced and rehabilitation-induced motor activity changes. Can J Physiol Pharmacol. 2018;96(11):1051–1059.
  • Racich MJ. Occlusion, temporomandibular disorders, and orofacial pain: an evidence-based overview and update with recommendations. J Prosthet Dent. 2018;120(5):678–685.
  • Shimada A, Ishigaki S, Matsuka Y, et al. Effects of exercise therapy on painful temporomandibular disorders. J Oral Rehabil. 2019;46(5):475–481.
  • Wieckiewicz M, Boening K, Wiland P, et al. Reported concepts for the treatment modalities and pain management of temporomandibular disorders. J Headache Pain. 2015;16(1):1–12.
  • Bronfort G, Haas M, Evans R, et al. Effectiveness of manual therapies: the UK evidence report. Chiropr Osteopat. 2010;18(3):1–33.
  • Butts R, Dunning J, Pavkovich R, et al. Conservative management of temporomandibular dysfunction: a literature review with implications for clinical practice guidelines (narrative review part 2). J Bodyw Mov Ther. 2017;21(3):541–548.
  • Jung A, Shin BC, Lee MS, et al. Acupuncture for treating temporomandibular joint disorders: a systematic review and meta-analysis of randomized, sham-controlled trials. J Dent. 2011;39(5):341–350.
  • Miernik M, Wieckiewicz M, Paradowska A, et al. Massage therapy in myofascial TMD pain management. Adv Clin Exp Med. 2012;21(5):681–685.
  • Abbasgholizadeh ZS, Evren B, Ozkan Y. Evaluation of the efficacy of different treatment modalities for painful temporomandibular disorders. Int J Oral Maxillofac Surg. 2019;20:20.
  • Del Vecchio A, Floravanti M, Boccassini A, et al. Evaluation of the efficacy of a new low-level laser therapy home protocol in the treatment of temporomandibular joint disorder-related pain: a randomized, double-blind, placebo-controlled clinical trial. Cranio. 2019;19:1–10.
  • Miletić A, Todorović A, Đorđević I, et al. Low-level laser therapy effectiveness in patients with temporomandibular disorders. Srpski Arhiv za Celokupno Lekarstvo. 2021;149:105.
  • Marini I, Gatto MR, Bonetti GA. Effects of superpulsed low-level laser therapy on temporomandibular joint pain. Clin J Pain. 2010;26(7):611–616.
  • Tengrungsun T, Mitrirattanakul S, Buranaprasertsuk P, et al. Is low level laser effective for the treatment of orofacial pain? A systematic review. Cranio. 2012;30(4):280–285.
  • Munguia FM, Jang J, Salem M, et al. Efficacy of low-level laser therapy in the treatment of temporomandibular myofascial pain: a systematic review and meta-analysis. J Oral Facial Pain Headache. 2018;32(3):287–297.
  • Shukla D, Muthusekhar MR. Efficacy of low-level laser therapy in temporomandibular disorders: a systematic review. Natl J Maxillofac Surg. 2016;7(1):62–66.
  • Xu G-Z, Jia J, Jin L, et al. Low-level laser therapy for temporomandibular disorders: a systematic review with meta-analysis. Pain Res Manag. 2018;2018:1–13.
  • Chen J, Huang Z, Ge M, et al. Efficacy of low‐level laser therapy in the treatment of TMDs: a meta‐analysis of 14 randomised controlled trials. J Oral Rehabil. 2015;42(4):291–299.
  • Herpich CM, Leal-Junior ECP, Gomes C, et al. Immediate and short-term effects of phototherapy on pain, muscle activity, and joint mobility in women with temporomandibular disorder: a randomized, double-blind, placebo-controlled, clinical trial. Disabil Rehabil. 2018;40(19):2318–2324.
  • Leite P, Melo N, Silva P, et al. Low-level laser therapy for temporomandibular disorders (TMD) treatment: a systematic review of randomized trials. J Res Dent. 2014;2(5):376–387.
  • Maia ML, Bonjardim LR, Quintans JDSS, et al. Effect of low-level laser therapy on pain levels in patients with temporomandibular disorders: a systematic review. J Appl Oral Sci. 2012;20(6):594–602.
  • Melis M, Di Giosia M, Zawawi KH. Low level laser therapy for the treatment of temporomandibular disorders: a systematic review of the literature. Cranio. 2012;30(4):304–312.
  • Petrucci A, Sgolastra F, Gatto R, et al. Effectiveness of low-level laser therapy in temporomandibular disorders: a systematic review and meta-analysis. J Orofac Pain. 2011;25(4):298–307.
  • Herranz-Aparicio J, Vázquez-Delgado E, Arnabat-Domínguez J, et al. The use of low level laser therapy in the treatment of temporomandibular joint disorders. Review of the literature. Med Oral Patol Oral Cir Bucal. 2013;18(4):e603–e612.
  • Glanville JM, Lefebvre C, Miles JN, et al. How to identify randomized controlled trials in MEDLINE: ten years on. J Med Libr Assoc. 2006;94(2):130–136.
  • Lennard TA, Vivian DG, Walkowski SD, et al. Pain procedures in clinical practice E-book. Springfield (MO): Elsevier Health Sciences; 2011.
  • de las Penas CF, Cleland J, Huijbregts P. Neck and arm pain syndromes. London (UK): Elsevier; 2011.
  • RoB CB. 2: a revised Cochrane risk-of-bias tool for randomized trials; 2020 [cited 2019 Dec 6]. Available from: bias/resources/rob-2-revised-cochrane-risk-bias-tool-randomized-trials
  • Armijo-Olivo S, Ospina M, da Costa BR, et al. Poor reliability between Cochrane reviewers and blinded external reviewers when applying the Cochrane risk of bias tool in physical therapy trials. PLOS One. 2014;9(5):e96920.
  • Balshem H, Helfand M, Schünemann HJ, et al. GRADE guidelines: 3. Rating the quality of evidence. J Clin Epidemiol. 2011;64(4):401–406.
  • Guyatt G, Oxman AD, Akl EA, et al. GRADE guidelines: 1. Introduction—GRADE evidence profiles and summary of findings tables. J Clin Epidemiol. 2011;64(4):383–394.
  • De Carli BM, Magro AK, Souza-Silva BN, et al. The effect of laser and botulinum toxin in the treatment of myofascial pain and mouth opening: a randomized clinical trial. J Photochem Photobiol B. 2016;159:120–123.
  • de Carli ML, Guerra MB, Nunes TB, et al. Piroxicam and laser phototherapy in the treatment of TMJ arthralgia: a double-blind randomised controlled trial. J Oral Rehabil. 2013;40(3):171–178.
  • Cavalcanti MF, Silva UH, Leal-Junior EC, et al. Comparative study of the physiotherapeutic and drug protocol and low-level laser irradiation in the treatment of pain associated with temporomandibular dysfunction. Photomed Laser Surg. 2016;34(12):652–656.
  • Conti PCR. Low level laser therapy in the treatment of temporomandibular disorders (TMD): a double-blind pilot study. Cranio. 1997;15(2):144–149.
  • de Godoy CHL, Motta LJ, Garcia EJ, et al. Electromyographic evaluation of a low-level laser protocol for the treatment of temporomandibular disorder: a randomized, controlled, blind trial. Lasers Surg Med. 2017;49(4):413.
  • Fikackova H, Dostalova T, Navratil L, et al. Effectiveness of low-level laser therapy in temporomandibular joint disorders: a placebo-controlled study. Photomed Laser Surg. 2007;25(4):297–303.
  • Kogawa EM, Kato MT, Santos CN, et al. Evaluation of the efficacy of low-level laser therapy (LLLT) and the microelectric neurostimulation (MENS) in the treatment of myogenic temporomandibular disorders: a randomized clinical trial. J Appl Oral Sci. 2005;13(3):280–285.
  • Machado BC, Mazzetto MO, Da Silva MA, et al. Effects of oral motor exercises and laser therapy on chronic temporomandibular disorders: a randomized study with follow-up. Lasers Med Sci. 2016;31(5):945–954.
  • Madani A, Ahrari F, Fallahrastegar A, et al. A randomized clinical trial comparing the efficacy of low-level laser therapy (LLLT) and laser acupuncture therapy (LAT) in patients with temporomandibular disorders. Lasers Med Sci. 2020;35(1):181–192.
  • León IG, Almagro S, García RC. Temporomandibular disorders and the application of laser therapy. Rev Cubana Estomatol. 2007;44(3).
  • Mazzetto MO, Hotta TH, Pizzo RC. Measurements of jaw movements and TMJ pain intensity in patients treated with GaAlAs laser. Braz Dent J. 2010;21(4):356–360.
  • Mazzetto MO, Carrasco TG, Bidinelo EF, et al. Low intensity laser application in temporomandibular disorders: a phase I double-blind study. Cranio. 2007;25(3):186–192.
  • Mounir RM, Hindy AM, Shaker MA. Different conservative modalities of treatment of T.M.J. arthralgia. Egypt Dent J. 1995;41(3):1247–1252.
  • Nunez SC, Garcez AS, Suzuki SS, et al. Management of mouth opening in patients with temporomandibular disorders through low-level laser therapy and transcutaneous electrical neural stimulation. Photomed Laser Surg. 2006;24(1):45–49.
  • Panhoca VH, Lizarelli RdFZ, Nunez SC, et al. Comparative clinical study of light analgesic effect on temporomandibular disorder (TMD) using red and infrared led therapy. Lasers Med Sci. 2015;30(2):815–822.
  • Rezazadeh F, Hajian K, Shahidi S, et al. Comparison of the effects of transcutaneous electrical nerve stimulation and low-level laser therapy on drug-resistant temporomandibular disorders. J Dent. 2017;18(3):187–192.
  • Rodrigues D, Siriani AO, Berzin F. Effect of conventional TENS on pain and electromyographic activity of masticatory muscles in TMD patients. Braz Oral Res. 2004;18(4):290–295.
  • Uemoto L, Garcia MA, Gouvea CV, et al. Laser therapy and needling in myofascial trigger point deactivation. J Oral Sci. 2013;55(2):175–181.
  • Demirkol N, Usumez A, Demirkol M, et al. Efficacy of low-level laser therapy in subjective tinnitus patients with temporomandibular disorders. Photomed Laser Surg. 2017;35(8):427–431.
  • De Oliveira RF, Da Silva CV, Cersosimo MCP, et al. Laser therapy on points of acupuncture: are there benefits in dentistry? J Photochem Photobiol B. 2015;151:76–82.
  • Gray RJ, Quayle AA, Hall CA, et al. Physiotherapy in the treatment of temporomandibular joint disorders: a comparative study of four treatment methods. Br Dent J. 1994;176(7):257–261.
  • Khairnar S, Bhate K, Santhosh Kumar SN, et al. Comparative evaluation of low-level laser therapy and ultrasound heat therapy in reducing temporomandibular joint disorder pain. J Dent Anesth Pain Med. 2019;19(5):289–294.
  • Magri LV, Carvalho VA, Rodrigues FC, et al. Effectiveness of low-level laser therapy on pain intensity, pressure pain threshold, and SF-MPQ indexes of women with myofascial pain. Lasers Med Sci. 2017;32(2):419–428.
  • Pereira TS, Flecha OD, Guimaraes RC, et al. Efficacy of red and infrared lasers in treatment of temporomandibular disorders – a double-blind, randomized, parallel clinical trial. Cranio. 2014;32(1):51–56.
  • Shirani AM, Gutknecht N, Taghizadeh M, et al. Low-level laser therapy and myofacial pain dysfunction syndrome: a randomized controlled clinical trial. Lasers Med Sci. 2009;24(5):715–720.
  • Valenzuela S, Lopez-Jornet P. Effects of low-level laser therapy on burning mouth syndrome. J Oral Rehabil. 2017;44(2):125–132.
  • Venezian GC, da Silva MA, Mazzetto RG, et al. Low level laser effects on pain to palpation and electromyographic activity in TMD patients: a double-blind, randomized, placebo-controlled study. Cranio. 2010;28(2):84–91.
  • Brochado FT, Jesus LH, Carrard VC, et al. Comparative effectiveness of photobiomodulation and manual therapy alone or combined in TMD patients: a randomized clinical trial. Braz Oral Res. 2018;32:e50.
  • Jurkowski P, Kostrzewa-Janicka J, Mierzwińska-Nastalska E. The use of biostimulatory laser in the treatment of temporomandibular joint disorders. Dent Med Probl. 2011;48(2):208–216.
  • Borges RMM, Cardoso DS, Flores BC, et al. Effects of different photobiomodulation dosimetries on temporomandibular dysfunction: a randomized, double-blind, placebo-controlled clinical trial. Lasers Med Sci. 2018;33(9):1859–1866.
  • Sancakli E, Gokcen-Rohlig B, Balik A, et al. Early results of low-level laser application for masticatory muscle pain: a double-blind randomized clinical study. BMC Oral Health. 2015;15(1):131.
  • Costa SAP, Florezi GP, Artes GE, et al. The analgesic effect of photobiomodulation therapy (830 nm) on the masticatory muscles: a randomized, double-blind study. Braz Oral Res. 2017;31:e107.
  • da Cunha LA, Firoozmand LM, da Silva AP, et al. Efficacy of low-level laser therapy in the treatment of temporomandibular disorder. Int Dent J. 2008;58(4):213–217.
  • Emshoff R, Bosch R, Pumpel E, et al. Low-level laser therapy for treatment of temporomandibular joint pain: a double-blind and placebo-controlled trial. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;105(4):452–456.
  • Ferreira LA, de Oliveira RG, Guimaraes JP, et al. Laser acupuncture in patients with temporomandibular dysfunction: a randomized controlled trial. Lasers Med Sci. 2013;28(6):1549–1558.
  • Frare JC, Nicolau RA. Clinical analysis of the effect of laser photobiomodulation (GaAs-904nm) on temporomandibular joint dysfunction. Braz J Phys Ther/Rev Bras Fisioter. 2008;12(1):37–42.
  • Herpich CM, Leal-Junior ECP, Politti F, et al. Intraoral photobiomodulation diminishes pain and improves functioning in women with temporomandibular disorder: a randomized, sham-controlled, double-blind clinical trial: intraoral photobiomodulation diminishes pain in women with temporomandibular disorder. Lasers Med Sci. 2020;35(2):439–445.
  • Kulekcioglu S, Sivrioglu K, Ozcan O, et al. Effectiveness of low-level laser therapy in temporomandibular disorder. Scand J Rheumatol. 2003;32(2):114–118.
  • Lassemi E, Jafari SM, Motamedi MHK, et al. Low-level laser therapy in the management of temporomandibular joint disorder. J Oral Laser Appl. 2008;8(2):83–86.
  • Magri LV, Carvalho VA, Rodrigues FCC, et al. Non-specific effects and clusters of women with painful TMD responders and non-responders to LLLT: double-blind randomized clinical trial. Lasers Med Sci. 2018;33(2):385–392.
  • de Moraes Maia ML, Ribeiro MA, Maia LG, et al. Evaluation of low-level laser therapy effectiveness on the pain and masticatory performance of patients with myofascial pain. Lasers Med Sci. 2014;29(1):29–35.
  • Rohlig BG, Kipirdi S, Meric U, et al. Masticatory muscle pain and low-level laser therapy: a double-blind and placebo-controlled study. Turk Fiziksel Tip ve Rehabil Dergisi. 2011;57(1):31–37.
  • Santos TdS, Piva MR, Ribeiro MH, et al. Lasertherapy efficacy in temporomandibular disorders: control study. Braz J Otorhinolaryngol. 2010;76(3):294–299.
  • Seifi M, Ebadifar A, Kabiri S, et al. Comparative effectiveness of low level laser therapy and transcutaneous electric nerve stimulation on temporomandibular joint disorders. J Lasers Med Sci. 2017;8(Suppl. 1):S27–S31.
  • Shobha R, Narayanan VS, Jagadish Pai BS, et al. Low-level laser therapy: a novel therapeutic approach to temporomandibular disorder – a randomized, double-blinded, placebo-controlled trial. Indian J Dent Res. 2017;28(4):380–387.
  • Wang X, Yang Z, Zhang W, et al. Efficacy evaluation of low-level laser therapy on temporomandibular disorder. Hua Xi Kou Qiang Yi Xue Za Zhi. 2011;29(4):399.
  • Buduru S, Talmaceanu D, Baru O, et al. Low-level laser therapy effects vs. placebo in the treatment of temporo-mandibular joint disorders. Balneo. 2018;9(3):281–284.
  • da Silva MA, Botelho AL, Turim CV, et al. Low level laser therapy as an adjunctive technique in the management of temporomandibular disorders. Cranio. 2012;30(4):264–271.
  • Carrasco TG, Guerisoli LD, Guerisoli DM, et al. Evaluation of low intensity laser therapy in myofascial pain syndrome. Cranio. 2009;27(4):243–247.
  • Cetiner S, Kahraman SA, Yücetaş S. Evaluation of low-level laser therapy in the treatment of temporomandibular disorders. Photomed Laser Surg. 2006;24(5):637–641.
  • Demirkol N, Sari F, Bulbul M, et al. Effectiveness of occlusal splints and low-level laser therapy on myofascial pain. Lasers Med Sci. 2015;30(3):1007–1012.
  • Magri LV, Bataglion C, Leite-Panissi CRA. Follow-up results of a randomized clinical trial for low-level laser therapy in painful TMD of muscular origins. Cranio. 2019;39:1–8.
  • Sattayut S, Bradley P. A study of the influence of low intensity laser therapy on painful temporomandibular disorder patients. Laser Ther. 2012;21(3):183–192.
  • Monteiro L, Ferreira R, Resende T, et al. Effectiveness of photobiomodulation in temporomandibular disorder-related pain using a 635 nm diode laser: a randomized, blinded, and placebo-controlled clinical trial. Photobiomodul Photomed Laser Surg. 2020;38(5):280–288.
  • Abreu Venancio R, Camparis CM, Fatima Zanirato Lizarelli R, et al. Low intensity laser therapy in the treatment of temporomandibular disorders: a double-blind study. J Oral Rehabil. 2005;32(11):800–807.
  • Varma SR, Shayeb MA, Kaseh AE, et al. Effectiveness of low-level laser therapy in the management of the temporomandibular joint disorders: a placebo-controlled trial. World J Dent. 2018;9(4):316–320.
  • Khosla B, Singh A, Agarwal N, et al. Comparative evaluation between the effects of low-intensity laser therapy and transcutaneous electric nerve stimulation on temporomandibular joint disorders. Int J Sci Study. 2015;3(6):86–92.
  • Kato MT, Kogawa EM, Santos CN, et al. TENS and low-level laser therapy in the management of temporomandibular disorders. J Appl Oral Sci. 2006;14(2):130–135.
  • Hosgor H, Bas B, Celenk C. A comparison of the outcomes of four minimally invasive treatment methods for anterior disc displacement of the temporomandibular joint. Int J Oral Maxillofac Surg. 2017;46(11):1403–1410.
  • Khalighi HR, Mortazavi H, Mojahedi SM, et al. Low level laser therapy versus pharmacotherapy in improving myofascial pain disorder syndrome. J Lasers Med Sci. 2016;7(1):45–50.
  • Najafi S, Farrokhnia T, Vahidi MR, et al. Clinical comparison of the effects of low level laser and naproxen on patients with myofascial pain disorder syndrome. J Iran Med Council. 2018;1(2):81–86.
  • Khiavi HA, Ebrahimi H, Najafi S, et al. Efficacy of low-level laser, hard occlusal appliance and conventional pharmacotherapy in the management of myofascial pain dysfunction syndrome: a preliminary study. J Lasers Med Sci. 2020;11(1):37–44.
  • Altindis T, Gungormus M. Thermographic evaluation of occlusal splint and low level laser therapy in myofascial pain syndrome. Complement Ther Med. 2019;44:277–281.
  • Oz S, Gokcen-Rohlig B, Saruhanoglu A, et al. Management of myofascial pain: low-level laser therapy versus occlusal splints. J Craniofac Surg. 2010;21(6):1722–1728.
  • Costa DR, Pessoa DR, Seefeldt VB, et al. Orofacial evaluation of individuals with temporomandibular disorder after LED therapy associated or not of occlusal splint: a randomized double-blind controlled clinical study. Lasers Med Sci. 2021;36(8):1681–1689.
  • Nadershah M, Abdel-Alim HM, Bayoumi AM, et al. Photobiomodulation therapy for myofascial pain in temporomandibular joint dysfunction: a double-blinded randomized clinical trial. J Maxillofac Oral Surg. 2020;19(1):93–97.
  • Ahrari F, Madani AS, Ghafouri ZS, et al. The efficacy of low-level laser therapy for the treatment of myogenous temporomandibular joint disorder. Lasers Med Sci. 2014;29(2):551–557.
  • Huang YF, Lin JC, Yang HW, et al. Clinical effectiveness of laser acupuncture in the treatment of temporomandibular joint disorder. J Formos Med Assoc. 2014;113(8):535–539.
  • Madani AS, Ahrari F, Nasiri F, et al. Low-level laser therapy for management of TMJ osteoarthritis. Cranio. 2014;32(1):38–44.
  • Bertolucci LE, Grey T. Clinical comparative study of microcurrent electrical stimulation to mid-laser and placebo treatment in degenerative joint disease of the temporomandibular joint. Cranio. 1995;13(2):116–120.
  • Bertolucci LE, Grey T. Clinical analysis of mid-laser versus placebo treatment of arthralgic TMJ degenerative joints. Cranio. 1995;13(1):26–29.
  • Rodrigues CA, Melchior MDO, Valencise Magri L, et al. Can the severity of orofacial myofunctional conditions interfere with the response of analgesia promoted by active or placebo low-level laser therapy? Cranio. 2018;23:1–8.
  • De Oliveira Chami V, Maracci LM, Tomazoni F, et al. Rapid LLLT protocol for myofascial pain and mouth opening limitation treatment in the clinical practice: an RCT. Cranio. 2022;40(4):334–340.
  • Chellappa D, Thirupathy M. Comparative efficacy of low-level laser and TENS in the symptomatic relief of temporomandibular joint disorders: a randomized clinical trial. Indian J Dent Res. 2020;31(1):42.
  • Herpich CM, Amaral AP, Leal-Junior EC, et al. Analysis of laser therapy and assessment methods in the rehabilitation of temporomandibular disorder: a systematic review of the literature. J Phys Ther Sci. 2015;27(1):295–301.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.