9
Views
6
CrossRef citations to date
0
Altmetric
Original Articles

Low prevalence of the intact cag pathogenicity island in clinical isolates of Helicobacter pylori in Karachi, Pakistan

, , , , , & show all
Pages 137-142 | Accepted 29 May 2009, Published online: 23 May 2016

References

  • Blaser MJ. Ecology of Helicobacter pylori in the human stomach. J Clin Invest 1997; 100: 759–62.
  • Blaser MJ, Perez-Perez GI, Kleanthous H et al. Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res 1995, 55: 2111–5.
  • Cover TL, Blaser MJ. Helicobacter pylori factors associated with disease. Gastroenterology 1999; 117: 257–61.
  • Censini S, Lange C, Xiang Z et al. Cag pathogenicity island of Helicobacter pylori encodes type-specific and disease-associated virulence factors. Proc Natl Acad Sci USA 1996; 93: 14648–53.
  • Karnholz A, Hoefler C, Odenbreit S, Fischer W, Hofreuter D, Haas R. Functional and topological characterization of novel components of the comB DNA transformation competence system in Helicobacter pylori. J Bacteriol 2006; 188: 882–93.
  • Fischer W, Jürgen PL, Buhrdorf R, Gebert B, Odenbreit S, Haas R. Systematic mutagenesis of the Helicobacter pylori cag pathogenicity island: essential genes for cagA translocation in host cells and induction of interleukin-8. Mol Microbiol 2001; 42: 1337–48.
  • van Doorn LJ, Figueiredo C, Sanna R, Blaser MJ, Quint WG. Distinct variants of Helicobacter pylori cagA are associated with vacA subtypes. J Clin Microbiol 1999; 37: 2306–11.
  • Xiang Z, Censini S, Bayeli PF et al. Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveal that clinical isolates can be divided into two major types and that cagA is not necessary for expression of the vacuolating cytotoxin. Infect Immun 1995; 63: 94–8.
  • Akopyants NS, Clifton SW, Kersulyte D et al. Analyses of the cag pathogenicity island of Helicobacter pylori. Mol Microbiol 1998; 28: 37–53.
  • Said RM, Cheah PL, Chin SC, Goh KL. Evaluation of a new biopsy urease test: Pronto Dry for the diagnosis of Helicobacter pylori infection. Eur J Gastroenterol Hepatol 2004; 16: 195–9.
  • Price AB. The Sydney System: histological division. J Gastroenterol Hepatol 1991; 6: 209–22.
  • Matteo MJ, Granados G, Pérez CV, Olmos M, Sanchez C, Catalano M. Helicobacter pylori cag pathogenicity island genotype diversity within the gastric niche of a single host. J Med Microbiol 2007; 56: 664–9.
  • Yakoob J, Hu GL, Fan XG et al. Diversity of Helicobacter pylori in Chinese persons with H. pylori infection. APMIS 2000; 108: 482–6.
  • Ikenoue T, Maeda S, Gura KO et al. Determination of Helicobacter pylori virulence by simple gene analysis of the cag pathogenicity island. Clin Diagn Lab Immunol 2001; 8: 181–6.
  • Tomb JF, White O, Kerlavage AR et al. The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature 1997; 338: 539–47.
  • Covacci A, Rappuoli R. PCR amplification of gene sequences from Helicobacter pylori strains. In: Helicobacter pylori: techniques for clinical diagnosis and basic research. Philadelphia: WB Saunders, 1996: 94–109.
  • Abbas Z, Jafri W, Khan AH, Shah MA. Prevalence of Helicobacter pylori antibodies in endoscopy personnel and non-medical volunteers of Karachi. J Pak Med Assoc 1998; 48: 201–3.
  • Nizami SQ, Bhutta ZA, Weaver L, Preston T. Helicobacter pylori colonization in infants in a peri-urban community in Karachi, Pakistan. J Pediatr Gastroenterol Nutr 2005; 4: 191–4.
  • Kauser F, Khan AA, Hussain MA et al. The cag pathogenicity island of Helicobacter pylori is disrupted in the majority of patient isolates from different human populations. J Clin Microbiol 2004; 42: 5302–8.
  • Mukhopadhyay AK, Kersulyte D, Jeong JY et al. Distinctiveness of genotypes of Helicobacter pylori in Calcutta, India. J Bacteriol 2000; 182: 3219–27.
  • Blaser MJ. Role of vacA and the cagA locus of Helicobacter pylori in human disease. Aliment Pharmacol Ther 1996; 10 (Suppl 1): 73–8.
  • Jenks PJ, Megraud F, Labigne A. Clinical outcome after infection with Helicobacter pylori does not appear to be reliably predicted by the presence of any of the genes of the cag pathogenicity island. Gut 1998; 43: 752–8.
  • Kidd M, Lastovica A, Atherton J, Louw JA. Heterogeneity in the Helicobacter pylori genes vacA and cagA: associated with gastroduodenal disease in South Africa? Gut 1999; 45: 499–503.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.