110
Views
5
CrossRef citations to date
0
Altmetric
Research Article

Apical transport of osteopontin is independent of N-glycosylation and sialylation

, &
Pages 275-281 | Published online: 09 Jul 2009

  • Alfalah, M, Jacob. R., Preuss, U., Zimmer, K. P., Main H. and Main H. Y., 1999, O-lnked grycans mediate apical sorting of human intestinal sucrase-isomaltase through association with lipid rate. Current Biology, 9, 593-596.
  • Brown, D. A., Crise, B. and Rose, J. K., 1989, Mechanism of membrane anchonrig affects polarized expression of two praters in MDCK cells. Science, 245, 1499-1501.
  • Butler, W. T., 1989, The nature and significance of osteopontin. Connective Tissue Research. 23,123-136.
  • Byrd, J. C., Dahiya, R., Huang, J. and Kin Y. S., 1995, lnhbition of mucin synthesis by benzyl-a-GalNAc in KATO III gastric cancer and Caco-2 colon cancer cells. European Journal of Cancer. 31 A, 1498-1505.
  • Chuang, J.-Z. and Sung, C.-K, 1998, The cytoplasmic tail of rhodopsin acts as a novel apical sorting signal in polarized MDCK cells. Journal of Cell Biology. 142, 1245-1256.
  • Fiedler, K. and Shuns, K., 1995, The role of N-glycans in the secretory pathway. Cell 81, 309-312.
  • Gonzalez, A., Nicovani, S. and Juica, F., 1993, Apical secretion of hepatitis B surface antigen from transfected Madin-Darby canine kidney cells. Journal of Biological Chemistry, 268, 6662- 6667.
  • Hauri, H-P., Appenzeller. C., Kühn, F. and Nufer, O., 2000, Lectins and traffic in the secretory pathway. FEBS Letters, 476, 32-37.
  • Heifetz, A., Keenan, R. W. and Eber, A. D., 1979, Mechanism of action of tunicamycin on the UDP-GlcNAc:dolichyl-phosphate GloNAc-1-phosphate transferase. Biochemistry, 18, 2186-2192.
  • Huang, J., Byrd, J. C., Yoon, W. H. and Kin Y. S., 1992, Effect of benzyl-a-GalNAc, an inhibitor of muer glycosylation, on cancerassociated antigens in human colon cancer cells. Oncology Research, 4, 507-515.
  • Huet, G., Hennebbq-Reig, S., de Bobs, C., Ulloa, F., Lesuffleur, T., Barbat A., Carrière, V., Kin I. Real, F. X., Delannoy, P. and Zwebaurn A., 1998, GalNAo-a-O-benzyl inhbits NeuAca2-3 glycosylation and blocks the intracellular transport of apical grycoproteins and mucus in differentiated HT-29 cells. Journal of Cell Biology. 141, 1311-1322.
  • Huet, G., Kin I., de Bolos, C., Lo-Guidbe, J. M, Mareau, O., Hemon, B., Richet C., Delannoy, P., Real, F. X. and Degand, P., 1995, Characterization of mucins and proteoglycans synthesized by a mucin-secretng HT-29 cell subpopulation. Journal of Cell Science, 108, 1275-1285.
  • Keller, P. and Simons, K., 1997, Post-Golgi biosynthetic trafficking. Journal of Cell Science. 110, 3001-3009.
  • Khagawa, Y., Sana Y., Ueda, M, Higashb, K., Marita, K, Okano, M, Matsumoto, S. and Sasaki, R., 1994, N-glycosytation of erythropoietin is critical for apical secretion by Madin-Darby canne kidney cells. Experimental Cell Research, 213. 449- 457.
  • Kuan, S.-F., Byrd, J. C. Basbaun C. and Kin Y. S., 1989, Inhibition of mucn glycosylation by aryl-N-acetyl-a-galactaeaminides in human colon cancer cells. Journal of Biological Chemistry, 264, 19271-19277.
  • Kühn, U., Cohn, D. V. and GOT, S. U., 2000, Polarized secretion of the regulated secretory protein chromogranin A. Biochemical and Biophysical Research Communications. 270, 631-636.
  • Larsen, J. E., Awakumov, G. V., Hammond, G. L and Vogel, L K., 1999, N-glycans are not the signal for apical sorting of corticosteroid binding globulin in MDCK cells. FEBS Letters, 451, 19-22.
  • Lisanti, M P., Caras, I. W., Davitz, M A. and Rodriguez-Boulan, E., 1989, A glycophoephoipid membrane anchor acts as an apical targeting signal ri polarized ephhelia I cells. Journal of Cell Biology. 109, 2145-2156.
  • Martinez-Maza, R., Poyatos, I., Lopez-Corcuera, B., Nunez, E., Grnenez, C., Zaire, F. and Aragon, C., 2001, The role of Nglycosylation in transport to the plasma membrane and sorting of the neuronal glycine transporter GLYT2. Journal of Biological Chemistry. 276, 2168-2173.
  • Marzolo, M P., Bull, P. and Gonzalez, A., 1997, Apical sorting of hepatitis B surface antigen (HBsAg) is independent of Nglycosylation and glycosylphosphatidyinasitol-anchored protein segregation. Proceedings of the National Academy of Sciences (USA). 94, 1834-1839.
  • Masuda, K., Takahashi, N, Tsukamoto, Y., Honma, H. and Kohri, K., 2000, N-glycan structures of an osteopontin from human bone. Biochemical and Biophysical Research Communications, 268, 814-817.
  • Matter, K. and Melbnan, I., 1994, Mechanisms of cell polarity: sorting and transport in epithelia I cells. Current Opinion in Cell Biology, 6, 545-554.
  • Manlauzeur, L, Breuza, L and Le Bivic, A., 1998, Putative Oglycosylation sites and a membrane anchor are necessary for apical delivery of the human neurotrophn receptor ri Caco-2 cells. Journal of Biological Chemistry, 273, 30263-30270.
  • Mostov, K. E. and Cardone, M K, 1995, Regulation of protein traffic in polarized epithelial cells. BioEssays, 17, 129-138.
  • Oldberg, A., Franzen, A. and Heinegard, D., 1986, Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-bridrig sequence. Proceedings of the National Academy of Sciences (USA). 83, 8819-8823.
  • Parczyk, K. and Koch-Brandt, C., 1991, The role of carbohydrates in vectoriel exocytosfe. The secretion of the gp 80 glycoprotein complex in a ricin-resislant mutant of MDCK cells. FEBS Letters. 278, 267-270.
  • Pinter, A. and Honnen, W. J., 1988, O-linked glycosylation of retrovral envelope gene products. Journal of Virology. 62, 10161021.
  • Rodriguez-Boulan, E. and Gonzalez, A., 1999, Glycans in post-Golgi apical targeting: sorting signals or structural props? Trends h Cell Biology. 9, 291-294.
  • Rodriguez-Boulan, E. and Nelson, W. J., 1989, Marphogenesis of the polarized epithelial cell phenotype. Science. 245, 718-725.
  • Scheiffele, P., Peränen, J. and Simons, K., 1995, N-glycans as apical sorting signals in epithelial cells. Nature, 378, 96-98.
  • Simons, K. and Ikonen, E., 1997, Functional rafts in cell membranes. Nature, 387, 569-572.
  • Singh, K., DeVouge, M W. and Mukherjee, B. B., 1990, Physiological properties and differential glycosylation of phosphcrylated and nonphosphcrylated forms of osteopontin secreted by normal rat kidney cells. Journal of Biological Chemistry, 265. 1869618701.
  • Slimane, T. A., Lenoir, C., Sapri, C., Maurice, M and Trugnan, G., 2000, Apical secretion and sialyation of soluble dipeptidyl peptidase IV are two related events. Experinental Cell Research, 258, 184-194.
  • Tam, B. M., Moritz, O. L., Hurd, L B. and Papermaster, D. S., 2000, Identification of an outer segment targeting signal in the COOH terminus of rhodopsin using transgenic Xenopus laevis. Journal of Cell Biology. 151, 1369-1380.
  • Tooze, S. A., Tooze, J. and Warren, G., 1988, Site of addition of Nacetyl-galactasamine to the E1 glycoprotein of mouse hepatitis virus-A59. Journal of Cell Biology, 106, 1475-1487.
  • Ulrich, O., Mann, K., Haase, W. and Koch-Brandt C., 1991, Biosynthesis and secretion of an osteopontin-related 20-kDa polypeptide in the Madin-Darby canine kidney cell line. Journal of Biological Chemistry, 266, 3518-3525.
  • Urban, J., Parczyk, K., Leutz, A., Kayne, M. and Kondor-Koch, C., 1987, Constitutive apical secretion of an 80-kD sulfated glycoprotein complex in the polarized ephhelia I Madin-Darby canine kidney cell line. Journal of Cell Biology, 105, 2735-2743.
  • Varki, A., 1994, Metaboic radblabeing of grycoconjugates. Methods n Enzymobbgy. 230, 16-32.
  • Wagner, M, Morgans, C. and Koch-Brandt, C., 1995, The digosaccharides have an essential but indrect role in sorting gp80 (clusterri, TRPM2) to the apical surface of MDCK cells. European Journal of Cell Biology. 67, 84-88.
  • Yeaman, C., Le Gall, A. H., Baldwin, A. N., Manlauzeur, L, Le Bivic, A and Rodriguez-Boulan, E., 1997, The O-glycpsylated stalk domain is required for apical sorting of neurotrophin receptors in polarized MDCK cells. Journal of Cell Biology. 139, 929-940.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.