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Research Article

Targeting motifs in GLUT4

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Pages 257-264 | Published online: 09 Jul 2009

  • Aiken, C., Konner, J., Landau, N. R., Lenbirg, M. E. and Trono, D., 1994, Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain. Cell. 76, 853-864.
  • Aledo, J. C., Darakhshan, F. and Hundal, H. S., 1995, Rab4, but not the transferrin receptor, is colocalized with GLUT4 in an insulinsensitive intracellular compartment in rat skeletal muscle. Biochemisty and Biophysics Research Communications. 215, 321328
  • Araki, S., Yang, J., Hashiramoto, M, Tamori, Y., Kasuga, M. and Holman, G. D., 1996, Subcellular trafficking kinetics of GLU4 mutated at the N- and C- terminal. Biochemistry Journal. 315, 153-159.
  • Chen, W. J., Goldstein, J. L and Brown, M S., 1990, NPXY, a sequence often found r cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor. Journal of Biological Chemistry, 265, 3116-3123.
  • Collawn, J. F., Stangel, M., Kuhn, L. A., Esekogwu, V., Jing, S. Q., Trowbridge, I. S. and Tainer, J. A., 1990, Transferrin receptor internalization sequence YXRF triplicates a tight turn as the structural recognition motif for endocytosis. Cell. 63,1061-1072.
  • Cope, D. L., Lee, S., Melvin, D. R. and Gould, G. W., 2000, Identification of further important residues within the Glut4 carboxy-terminal tail which regulate subcellular trafficking. FEBS Letters, 481, 261-265.
  • Corvera, S., Chawla, A., Chakrabarti, R., JoIy, M., Buxton, J. and Czech, M P., 1994, A double leucine within the GLUT4 glucose transporter COOH-terminal domar functions as an endocytosis signal. Journal of Cell Biology. 126, 979-989.
  • Czech, M. P., Chawb, A., Woon, C. W., Buxton, J., Armoni, M, Tang, W., JoIy, M and Corvera, S., 1993, Exofacial epitopetagged glucose transporter chineras reveal COOH- terminal sequences governing cellular localization. Journal of Cell Biology. 123,127-135.
  • Dobson, S. P., Livingstone, C., Gould, G. W. and Tavare, J. M, 1996, Dynamics of insulin-stimulated translocation of GLUT4 in single living cells visualised using green fluorescent protein. FEBS Letters, 393, 179-847.
  • Garippa, R. J., Johnson, A., Park, J., Petrush, R. L and McGraw, T. E., 1996, The carboxyl terminus of GLUT4 contains a serineleucine-leucine sequence that functions as a potent internalization motif in Chinese hamster ovary cells. Journal of Biological Chemistry, 271, 20660-20668.
  • Garippa, R. J., Judge, T. W., James, D. E. and McGraw, T. E., 1994, The aminoterminus of GLUT4 functions as an internaization motif but not an intracellular retention signal when substituted for the transferrin receptor cytaplasmic domain. Journal of Cell Biology, 124, 705-715.
  • Guamieri, F. G., Altertum, L M, Penno, M B., Cha, Y. and August J. T., 1993, The motif Tyr-X-X-hydrophobic residue mediates lysosomal membrane targeting of lysosome-associated membrane protein 1. Journal of Biological Chemistry. 268,1941-1946.
  • Haney, P. M, Levy, M. A., Strube, M. S. and Mueckler, M., 1995, Insulin-sensitive targeting of the GLUT4 glucose transporter in L6 myoblasts is conferred by its COOH-terminal cytopbsmic teil. Journal of Cell Biology. 129, 641-658.
  • Herman, G. A., Bonzelius, F., Cieutat, A. M. and Kelly, R. B., 1994, A distinct class of intracellular storage vesicles, identified by expression of the glucose transporter GLUT4. Proceedings of the National Academy of Sciences (USA), 91, 12750-12754.
  • Holman, G. D. and Sandoval, I. V., 2001, Moving the insuinregulated glucose transporter GLUT4 into and out of storage. Trends in Cell Biology, 11,173-179.
  • Hudson, A. W., Fingar, D. C., Seidner, G. A., Griffiths, G., Burke, B. and Birnbaum, M. J., 1993, Targeting of the ' insuin-responsive' glucose transporter (GLUT4) to the regulated secretory pathway in PC12cells. Journal of Cell Biology, 122, 579-588.
  • Hunzker, W., Harter, C., Matter, K. and Mellman, I., 1991, Basolateral sorting in NDCK cells requires a distinct cytoplasmic domain determinant Cell. 66, 907-920.
  • James, D. E., Brown, R., Navarro, J. and Pilch, P. F., 1988, lnsulinregulatable tissues express a unique insulin-sensitive glucose transport prater. Nature, 333,183-185.
  • Johnson, A. O., Subtil, A., Petrush, R., Kobylarz, K., Keller, S. R. and McGraw, T. E., 1998, Identification of an insulin-responsive, slow endocytic recycling mechanism in Chinese hamster ovary cells. Journal of Biological Chemistry, 273, 17968-17977.
  • Kanai, F., Nishioka, Y., Hayashi, H., Kamohara, S., Todaka, M and Ebina, Y., 1993, Direct demonstration of insulin-induced GLUT4 translocation to the surface of intact cells by insertion of a c-myc epitope into an exofacial GLUT4 domain. Journal of Biological Chemistry, 268, 14523-14526.
  • Khan, A. H., Thumond, D. C., Yang, C., Ceresa, B. P., Sigmund, C. D. and Pessin, J. E., 2001, Munc 8c regulates insulin-stimulated glut4 translocation to the transverse tubules in skeletal muscle. Journal of Biological Chemistry, 276, 4063-4069.
  • Letourneur, F. and Klausner, R. D., 1992, A novel di-teucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CDS chars. Cell, 69,1143-1157.
  • Lund, S., Holman, G. D., Schmitz, O. and Pedersen, O., 1995, Contraction stimulates translocation of glucose transporter GLUT4 r skeletal muscle through a mechanism distinct from that of insulin. Proceedings of the National Academy of Sciences (USA), 92 5817-5821
  • Martinez-Arca, S., Lalioti, V. S. and Sandoval, I. V., 2000, lntracellular targeting and retention of the glucose transporter GLUT4 by the perinuclear storage compartment involves distinct carboxyl-tail motifs. Journal of Cell Science, 113,1705-1715.
  • Matter, K., Yamamoto, E. M and Mellman, I., 1994, Structural requirements and sequence motifs for polarized sorting and endocytosis of LDL and Fc receptors in MDCK cells. Journal of Cell Biology. 126. 991-1004.
  • Melvin, D. R., Marsh, B. J., Walmsley, A. R., James, D. E. and Gould, G. W., 1999, Analysis of amino and carboxy terminal GLUT-4 targeting motifs in 3T3- L1 adipocytes using an endosomal ablation technique. Biochemistry, 38,1456-1462.
  • Nielsen, M S., Madsen, P., Christensen, E. I., Nykjaer, A., Gliemann, J., Kasper, D., Pohlmann, R. and Petersen, C. M, 2001, The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting prater. EMBO Journal, 20, 2180-2190.
  • Oatey, P. B., Van Weering, D. H., Dobson, S. P., Gould, G. W. and Tavare, J. M, 1997, GLUT4 vesicle dynamics in living 3T3 L1 adipocytes visualized with green-fluorescent prater. Biochemistry Journal, 327, 637-642.
  • Palacios, S., Lalioti, V., Martinez-Arca, S., Chattopadhyay, S. and Sandoval, I. V., 2001, Recycling of the insulin-sensitive glucose transporter glut4. access of surface internalized glut4 molecules to the perinuclear storage compartment is mediated by the phe5gln6-gln7-ile8 motif. Journal of Biological Chemistry, 276, 33713383.
  • Patki, V., Buxton, J., Chawta, A., Lifeshitz, L, Fogarty, K., Carrington, W., Tuft, R. and Corvera, S., 2001, lnsulin action on GLUT4 traffic visualized in single 3T3-I1 adipocytes by using ultra-fast microscopy. Molecular Biology of the Cell, 12,129-141.
  • Pieters, J., Bakke, O. and Dobberster, B., 1993, The MHC class IIassociated invariant chain contains two endosomal targeting signals within its cytoplasmic tail. Journal of Cell Science, 106, 831-846.
  • Piper, R. C., Tai, C., Kulesza, P., Pang, S., Warnock, D., Baenziger, J., Slot J. W., Geuze, H. J., Puri, C. and James, D. E., 1993, GLUT-4 NH2 terminus contains a phenylalanine-based targeting motif that regulates intracellular sequestration. Journal of Cell Biology. 121, 1221-1232.
  • Piper, R. C., Tai, C., Slot J. W., Hahn, C. S., Rice, C. M, Huang, H. and James, D. E., 1992, The efficient intracellular sequestration of the insulin-regulatable glucose transporter (GLUT-4) is conferred by the NH2 terminus. Journal of Cell Biology. 117, 729-743.
  • Rodnick, K. J., Piper, R. C., Slot J. W. and James, D. E., 1992, Interaction of insulin and exercise on glucose transport in muscle. Diabetes Care. 15, 1679-1689.
  • Sandoval, I. V., Arredondo, J. J., Alcalde, J., Gonzalez Noriega, A., Vandekerckhove, J., Jimenez, M. A. and Rico, M, 1994, The residues Leu(lle)475-lle(Leu, VaI, Ala)476, centered in the extended carboxyl cytoplasmic tail, are critical for targeting of the resident lysosomal membrane protein LIMP Il to lysosomes. Journal of Biological Chemistry. 269, 6622-6631.
  • Sandoval, I. V., Martinez-Arca, S., Valdueza, J., Palados, S. and Holman, G. D., 2000, A family of leucine-based motifs: distinct reading of different structural determinants modulates the dileucine-mediated transport steps of the lysosomal membrane protein LIMPII and the insulin- sensitive glucose transporter GLUT4. Journal of Biological Chemistry, 275, 3974-3985.
  • Shewn, A. M, Marsh, B. J., Melvin, D. R., Martin, S., Gould, G. W. and James, D. E., 2000, The cytosolic C-terminus of the glucose transporter GLUT4 centers an acidic cluster endosomal targeting motif distal to the dileucine signal. Biochemistry Journal, 350,99-107.
  • Slot, J. W., Geuze, H. J., Gigengack, S., Lienhard, G. E. and James, D. E., 1991, Immuno-localization of the insulin regulatable glucose transporter in brown adipose tissue of the rat Journal of Cell Biology, 113,123-135.
  • Tikkanen, R., Obermuller, S., Denzer, K., Pungitore, R., Geuze, H. J, von Figura, K. and Honing, S., 2000, The dileucine motif within the tail of MPR46 is required for sorting of the receptor in endosomes. Traffic, 1, 631-640.
  • Tooze S. A., 2001, GGAs tie up the loose ends. Science. 292,1712-1716.
  • Verhey, K. J. and Birnbaum, M. J., 1994, A Leu-Leu sequence is essential for COOH-terminal targeting signal of GLUT4 glucose transporter in fibroblasts. Journal of Biological Chemistry, 269, 2353-2356.
  • Verhey, K. J., Yeh, J. I. and Birnbaum M. J., 1995, Distinct signa Is in the GLUT4 glucose transporter for internalization and for targeting to an insuin-responsive compartment Journal of Cell Biology. 130,1071-1079.
  • Xiang, Y., Molloy, S. S., Thomas, L and Thomas, G., 2000. The PC6B cytoplasmic daman contains two acidic clusters that direct sorting to distinct trans-Golgi network/endosomal compartments. Molecular Biology of the Cell, 11, 1257-1273.
  • Yeh, J. I., Verhey, K. J. and Birnbaum, M. J., 1995, Kinetic analysis of glucose transporter trafficking in ffcroblasts and adipocytes. Biochemistry, 34, 15523-15531.

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