- Zerial, M. and McBride, H., 2001, Rab proteins as membrane organizers. Nat. Rev. Mol. Cell Biol., 2, 107-117.
- Donaldson, J. G. and Jackson, C. L., 2000, Regulators and effectors of the ARF GTPases. Curr. Opin. Cell Biol., 12, 475482.
- Garcia-Ranea, J. A. and Valencia, A., 1998, Distribution and functional diversification of the ras super-family in Saccharomyces cerevisiae. FEBS Lett., 434, 219-225.
- Pereira-Leal, J. B. and Seabra, M. C., 2000, The mammalian Rab family of small GTPases: definition of family and subfamily sequence motifs suggests a mechanism for functional specificity in the Ras superfamily. J. Mol. Biol., 301, 1077-1087.
- Christoforidis, S., Miaczynska, M., Ashman, K., Wilm, M., Zhao, L., Yip, S. C., Waterfield, M. D., Backer, J. M. and Zerial, M., 1999, Phosphatidylinositol-3-OH kinases are Rab5 effectors. Nat. Cell Biol., 1, 249-252.
- Finger, F. P., Hughes, T. E. and Novick, P., 1998, Sec3p is a spatial landmark for polarized secretion in budding yeast. Cell, 92, 559-571.
- Nielsen, E., Christoforidis, S., Uttenweiler-Joseph, S., Miaczynska, M., Dewitte, F., Wilm, M., Hoflack, B. and Zerial, M., 2000, Rabenosyn-5, a novel Rab5 effector, is complexed with MVPS45 and recruited to endosomes through a FYVE finger domain. J. Cell Biol., 151, 601-612.
- Ren, M., Zeng, J., De Lemos-Chiarandini, C., Rosenfeld, M., Adesnik, M. and Sabatini, D. D., 1996, In its active form, the GTP-binding protein rab8 interacts with a stress-activated protein kinase. Proc. Natl. Acad. Sci., USA. 93, 5151-5155.
- Seabra, M. C., Mules, E. H. and Hume, A. N., 2002, Rab GTPases, intracellular traffic and disease. Tr. Mol. Med., 8, 23-30.
- Lin, R., Bagrodia, S., Cerione, R. and Manor, D., 1997, A novel Cdc42Hs mutant induces cellular transformation. Curr. Biol., 7, 794-797.
- Rybin, V., Ullrich, O., Rubino, M., Alexandrov, K., Simon, I., Seabra, M. C., Goody, R. and Zerial, M., 1996, GTPase activity of Rab5 acts as a timer for endocytic membrane fusion. Nature, 383, 266-269.
- Dirac-Svejstrup, A. B., Soldati, T., Shapiro, A. D. and Pfeffer, S. R., 1994, Rab-GDI presents functional Rab9 to the intracellular transport machinery and contributes selectivity to Rab9 membrane recruitment. J. Biol. Chem., 269, 15427-15430.
- Dirac-Svejstrup, A. B., Sumizawa, T. and Pfeffer, S. R., 1997, Identification of a GDI displacement factor that releases endosomal Rab GTPases from Rab-GDI. EMBO J., 16, 465-472.
- Spang, A., 2002, ARF1 regulatory factors and COPI vesicle formation. Curr. Opin. Cell Biol., 14, 423.
- Pfeffer, S., 1999, Transport-vesicle targeting: tethers before SNAREs. Nature Cell Biol., 1, E17-E22.
- Collins, R. N. and Brennwald, P., 2000, Rab proteins. Frontiers Mol. Biol., 24, 137-175.
- Segev, N., 2001, Ypt and Rab GTPases: insight into functions through novel interactions. Curr. Opin. Cell Biol., 13, 500-511.
- Munro, S., 2002, Organelle identity and the targeting of peripheral membrane proteins. Curr. Opin. Cell Biol., 14, 506.
- Cao, X. and Barlowe, C., 2000, Asymmetric requirements for a Rab GTPase and SNARE proteins in fusion of COPII vesicles with acceptor membranes. J. Cell Biol., 149, 55-66.
- Stinchcombe, J. C., Barrai, D. C., Mules, E. H., Booth, S., Hume, A. N., Machesky, L. M., Seabra, M. C. and Griffiths, G. M., 2001, Rab27a is required for regulated secretion in cytotoxic T lymphocytes. J. Cell Biol., 152, 825-834.
- Goldberg, J., 1998, Structural basis for activation of ARF GTPase: mechanisms of guanine nucleotide exchange and GTP-myristoyl switching. Cell, 95, 237-248.
- Peyroche, A., Paris, S. and Jackson, C. L., 1996, Nucleotide exchange on ARF mediated by yeast Gea1 protein. Nature, 384, 479-481.
- Brown, M. T., Andrade, J., Radhakrishna, H., Donaldson, J. G., Cooper, J. A. and Randazzo, P. A., 1998, ASAP1, a phospholipid-dependent art GTPase-activating protein that associates with and is phosphorylated by Src. Mol. Cell Biol., 18, 7038-7051.
- Turner, C. E., West, K. A. and Brown, M. C., 2001, Paxillin-ARF GAP signalling and the cytoskeleton. Curr. Opin. Cell Biol., 13, 593-599.
- Matsuoka, K., Orel, L., Amherdt, M., Bednarek, S. Y., Hamamoto, S., Schekman, R. and Yeung, T., 1998, COPII-coated vesicle formation reconstituted with purified coat proteins and chemically defined liposomes. Cell, 93, 263-275.
- Dumas, J. J., Merithew, E., Sudharshan, E., Rajamani, D., Hayes, S., Lawe, D., Corvera, S. and Lambright, D. G., 2001, Multivalent endosome targeting by homodimeric EEAI. Mol. Cell, 8, 947-958.
- Thaw, P., Baxter, N. J., Hounslow, A. M., Price, C., Waltho, J. P. and Craven, C. J., 2001, Structure of TCTP reveals unexpected relationship with guanine nucleotide-free chaperones. Nat. Struct. Biol., 8, 701-704.
- Ostermeier, C. and Brunger, A. T., 1999, Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A. Cell, 96, 363-374.
- Rak, A., Fedorov, R., Alexandrov, K., Albert, S., Goody, R. S., Gallwitz, D. and Scheidig, A. J., 2000, Crystal structure of the GAP domain of Gyp1p: first insights into interaction with Ypt/Rab proteins. EMBO J., 19, 5105-5113.
- Goldberg, J., 1999, Structural and functional analysis of the ARF1-ARFGAP complex reveals a role for coatomer in GTP hydrolysis. Cell, 96, 893-902.
- Goldberg, J., 2000, Decoding of sorting signals by coatomer through a GTPase switch in the COPI coat complex. Cell, 100, 671-679.
- Bi, X., Corpina, R. A. and Goldberg, J., 2002, Structure of the Sec23/24-Sar1 pre-budding complex of the COPII vesicle coat. Nature, 419, 271-277.
- Nagano, F., Kawabe, H., Nakanishi, H., Shinohara, M., Deguchi-Tawarada, M., Takeuchi, M., Sasaki, T. and Takai, Y., 2002, Rabconnectin-3, a novel protein that binds both GDP/GTP exchange protein and GTPase-activating protein for Rab3 small G protein family. J. Biol. Chem., 277, 9629-9632.
- Barr, F. A., 1999, A novel Rab6-interacting domain defines a family of Golgi-targeted coiled-coil proteins. Curr. Biol., 9, 381-384.
- Kjer-Nielsen, L., Teasdale, R. D., van Vliet, C. and Gleeson, P. A., 1999, A novel Golgi-localisation domain shared by a class of coiled-coil peripheral membrane proteins. Curr. Biol., 9, 385-388.
- Munro, S. and Nichols, B. J., 1999, The GRIP domain - a novel Golgi-targeting domain found in several coiled-coil proteins. Curr. Biol., 9, 377-380.
- Short, B., Preisinger, C., Schaletzky, J., Kopajtich, R. and Barr, F. A., 2002, The Rab6 GTPase Regulates Recruitment of the Dynactin Complex to Golgi Membranes. Curr. Biol., 12, 17921795.
- Echard, A., Jollivet, F., Martinez, O., Lacapere, J. J., Rousselet, A., Janoueix-Lerosey, I. and Goud, B., 1998, Interaction of a Golgi-associated kinesin-like protein with Rab6. Science, 279, 580-585.
- Hill, E., Clarke, M. and Barr, F. A., 2000, The Rate-binding kinesin, Rab6-KIFL, is required for cytokinesis. EMBO J., 19, 5711-5719.
- Monier, S., Jollivet, F., Janoueix-Lerosey, I., Johannes, L. and Goud, B., 2002, Characterization of novel Rab6-interacting proteins involved in endosome-to-TGN transport. Traffic, 3, 289-297.
- Siniossoglou, S. and Pelham, H. R., 2002, Vps51p links the VFT complex to the SNARE TIg1p. J. Biol. Chem., 107.
- Siniossoglou, S. and Pelham, H. R., 2001, An effector of Ypt6p binds the SNARE TIg1p and mediates selective fusion of vesicles with late Golgi membranes. EMBO J., 20, 59915998.
- Diaz, E., Schimmoller, F. and Pfeffer, S. R., 1997, A novel Rab9 effector required for endosome-to-TGN transport. J. Cell Biol., 138, 283-290.
- Carroll, K. S., Hanna, J., Simon, l., Krise, J., Barbero, P. and Pfeffer, S. R., 2001, Role of Rab9 GTPase in facilitating receptor recruitment by TIP47. Science, 292, 1373-1376.
- Wang, Y., Okamoto, M., Schmitz, F., Hofmann, K. and Sudhof, T. C., 1997, Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion. Nature, 388, 593-598.
- Ozaki, N., Shibasaki, T., Kashima, Y., Miki, T., Takahashi, K., Ueno, H., Sunaga, Y., Yano, H., Matsuura, Y., Iwanaga, T., Takai, Y. and Seino, S., 2000, cAMP-GEFII is a direct target of cAMP in regulated exocytosis. Nat. Cell Biol., 2, 805-811.
- Schoch, S., Castillo, P. E., Jo, T., Mukhenee, K., Geppert, M., Wang, Y., Schmitz, F., Malenka, R. C. and Sudhof, T. C., 2002, RIM1alpha forms a protein scaffold for regulating neurotransmitter release at the active zone. Nature, 415, 321-326.
- Ohtsuka, T., Takao-Rikitsu, E., lnoue, E., lnoue, M., Takeuchi, M., Matsubara, K., Deguchi-Tawarada, M., Satoh, K., Morimoto, K., Nakanishi, H. and Takai, Y., 2002, Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1. J. Cell Biol., 158, 577-590.
- Kalo, M., Sasaki, T., Ohya, T., Nakanishi, H., Nishioka, H., Imamura, M. and Takai, Y., 1996, Physical and functional interaction of rabphilin-3A with alpha-actinin. J. Biol. Chem., 271, 31775-31778.
- Ohya, T., Sasaki, T., Kalo, M. and Takai, Y., 1998, Involvement of Rabphilin3 in endocytosis through interaction with Rabaptin5. J. Biol. Chem., 273, 613-617.
- Tall, G. G., Hama, H., DeWaId, D. B. and Horazdovsky, B. F., 1999, The phosphatidylinositol 3-phosphate binding protein Vac1p interacts with a Rab GTPase and a Sec1p homologue to facilitate vesicle-mediated vacuolar protein sorting. Mol. Biol. Cell, 10, 1873-1889.
- Peterson, M. R., Burd, C. G. and Emr, S. D., 1999, Vac1p coordinates Rab and phosphatidylinositol 3-kinase signalling in Vps45p-dependent vesicle docking/fusion at the endosome. Curr. Biol., 9, 159-162.
- Kauppi, M., Simonsen, A., Bremnes, B., Vieira, A., Callaghan, J., Stenmark, H. and Olkkonen, V. M., 2002, The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking. J. Cell Sci., 115, 899-911.
- Simonsen, A., Gaullier, J. M., D'Arrigo, A. and Stenmark, H., 1999, The Rab5 effector EEA1 interacts directly with syntaxin6. J. Biol. Chem., 274, 28857-28860.
- McBride, H. M., Rybin, V., Murphy, C., Giner, A., Teasdale, R. and Zerial, M., 1999, Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13. Cell, 98, 377-386.
- Vitale, G., Rybin, V., Christoforidis, S., Thomqvist, P., McCaffrey, M., Stenmark, H. and Zerial, M., 1998, Distinct Rabbinding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5. EMBO J., 17, 1941-1951.
- Cormont, M., Mari, M., Galmiche, A., Hofman, P. and Le Marchand-Brustel, Y., 2001, A FYVE-finger-containing protein, Rabip4, is a Rab4 effector involved in early endosomal traffic. Proc. Natl. Acad. Sci., USA, 98, 1637-1642.
- Gerez, L., Mohrmann, K., van Raak, M., Jongeneelen, M., Zhou, X. Z., Lu, K. P. and van Der Sluijs, P., 2000, Accumulation of rab4GTP in the cytoplasm and association with the peptidyl-prolyl isomerase pin1 during mitosis. Mol. Biol. Cell, 11, 2201-2211.
- Zeng, J., Ren, M., Gravotta, D., De Lemos-Chiarandini, C., Lui, M., Erdjument-Bromage, H., Tempst, P., Xu, G., Shen, T. H., Morimoto, T., Adesnik, M. and Sabatini, D. D., 1999, Identification of a putative effector protein for rab11 that participates in transferrin recycling. Proc. Natl. Acad. Sci., USA, 96, 28402845.
- Mammoto, A., Ohtsuka, T., Hotta, I., Sasaki, T. and Takai, Y., 1999, RabHBP/Rabphilin-11, a downstream target of rab11 small G protein implicated in vesicle recycling. J. Biol. Chem., 274, 25517-25524.
- Mammoto, A., Sasaki, T., Kim, Y. and Takai, Y., 2000, Physical and functional interaction of rabphilin-11 with mammalian Sec13 protein. Implication in vesicle trafficking. J. Biol. Chem., 275, 13167-13170.
- Prekeris, R., Klumperman, J. and Scheller, R. H., 2000, A Rab11/Rip11 protein complex regulates apical membrane trafficking via recycling endosomes. Mol. Cell, 6, 1437-1448.
- Lindsay, A. J., Hendrick, A. G., Cantalupo, G., Senic-Matuglia, F., Goud, B., Bucci, C. and McCaffrey, M. W., 2002, Rab coupling protein (RCP), a novel Rab4 and Rab11 effector protein. J. Biol. Chem., 277, 12190-12199.
- Short, B., Preisinger, C., Komer, R., Kopajtich, R., Byron, O. and Barr, F. A., 2001, A GRASP55-rab2 effector complex linking Golgi structure to membrane traffic. J. Cell Biol., 155, 877-883.
- Weide, T., Bayer, M., Koster, M., Siebrasse, J. P., Peters, R. and Bamekow, A., 2001, The Golgi matrix protein GM130: a specific interacting partner of the small GTPase rab1b. EMBO Rep., 2, 336-341.
- Valsdottir, R., Hashimoto, H., Ashman, K., Koda, T., Storrie, B. and Nilsson, T., 2001, Identification of rabaptin-5, rabex-5, and GM130 as putative effectors of Rab33b, a regulator of retrograde traffic between the Golgi apparatus and ER. FEBS Lett., 508, 201-209.
- Allan, B. B., Moyer, B. D. and Balch, W. E., 2000, Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion. Science, 289, 444-448.
- Suvorova, E. S., Duden, R. and Lupashin, V. V., 2002, The Sec34/Sec35p complex, a Ypt1p effector required for retrograde intra-Golgi trafficking, interacts with Golgi SNAREs and COPI vesicle coat proteins. J. Cell Biol., 157, 631-643.
- Jones, S., Newman, C., Liu, F. and Segev, N., 2000, The TRAPP complex is a nucleotide exchanger for Ypt1 and Ypt31/ 32. Mol. Biol. Cell, 11, 4403-4411.
- Wang, W., Sacher, M. and Ferro-Novick, S., 2000, TRAPP stimulates guanine nucleotide exchange on Ypt1p. J. Cell Biol., 151, 289-296.
- Torii, S., Zhao, S., Yi, Z., Takeuchi, T. and Izumi, T., 2002, Granuphilin modulates the exocytosis of secretory granules through interaction with syntaxin 1a. Mol. Cell Biol., 22, 55185526.
- Coppola, T., Frantz, C., Perret-Menoud, V., Gattesco, S., Hiding, H. and Regazzi, R., 2002, Pancreatic beta-cell protein granuphilin binds Rab3 and Munc-18 and controls exocytosis. Mol. Biol. Cell, 13, 1906-1915.
- EI-Amraoui, A., Schonn, J. S., Kussel-Andermann, P., Blanchard, S., Desnos, C., Henry, J. P., Wolfrum, U., Darchen, F. and Petit, C., 2002, MyRIP, a novel Rab effector, enables myosin Vlla recruitment to retinal melanosomes. EMBO Rep., 3, 463-470.
- Guo, W., Roth, D., Walch-Solimena, C. and Novick, P., 1999, The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis. EMBO J., 18, 1071-1080.
- Adamo, J. E., Moskow, J. J., Gladfelter, A. S., Viterbo, D., Lew, D. J. and Brennwald, P. J., 2001, Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud. J. Cell Biol., 155, 581-592.
- Sugihara, K., Asano, S., Tanaka, K., Iwamatsu, A., Okawa, K. and Ohta, Y., 2002, The exocyst complex binds the small GTPase RaIA to mediate filopodia formation. Nat. Cell Biol., 4, 73-78.
- Zhang, X., Bi, E., Novick, P., Du, L., Kozminski, K. G., Lipschutz, J. H. and Guo, W., 2001, Cdc42 interacts with the exocyst and regulates polarized secretion. J. Biol. Chem., 276, 46745-46750.
- Ortz, D., Medkova, M., Walch-Solimena, C. and Novick, P., 2002, Ypt32 recruits the Sec4p guanine nucleotide exchange factor, Sec2p, to secretory vesicles; evidence for a Rab cascade in yeast. J. Cell Biol., 157, 1005-1015.
- Seals, D. F., Eitzen, G., Margolis, N., Wickner, W. T. and Price, A., 2000, A Ypt/Rab effector complex containing the Sect homolog Vps33p is required for homotypic vacuole fusion. Proc. Natl. Acad. Sci., USA, 97, 9402-9407.
- Cantalupo, G., Alifano, P., Robert, V., Bruni, C. B. and Bucci, C., 2001, Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes. EMBO J., 20, 683-693.
- Jordens, I., Fernandez-Borja, M., Marsman, M., Dusseljee, S., Janssen, L., Calafat, J., Janssen, H., Wubbolts, R. and Neefjes, J., 2001, The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dyneindynactin motors. Cum Biol., 11, 1680-1685.
- Cuif, M. H., Possmayer, F., Zander, H., Bordes, N., Jollivet, F., Couedel-Courteille, A., Janoueix-Lerosey, I., Langsley, G., Bomens, M. and Goud, B., 1999, Characterization of GAPCenA, a GTPase activating protein for Rab6, part of which associates with the centrosome. EMBO J., 18, 1772-1782.
- Iwasaki, K. and Toyonaga, R., 2000, The Rab3 GDP/GTP exchange factor homolog AEX-3 has a dual function in synaptic transmission. EMBO J., 19, 4806-4816.
- Du, L. L., Collins, R. N. and Novick, P. J., 1998, Identification of a Sec4p GTPase-activating protein (GAP) as a novel member of a Rab GAP family. J. Biol. Chem., 273, 32533256.
- Bi, E., Chiavetta, J. B., Chen, H., Chen, G. C., Chan, C. S. and Pringle, J. R., 2000, Identification of novel, evolutionarily conserved Cdc42p-interacting proteins and of redundant pathways linking Cdc24p and Cdc42p to actin polarization in yeast. Mol. Biol. Cell, 11, 773-793.
- Strom, M., Vollmer, P., Tan, T. J. and Gallwitz, D., 1993, A yeast GTPase-activating protein that interacts specifically with a member of the Ypt/Rab family. Nature, 361, 736-739.
- Vollmer, P., Will, E., Scheglmann, D., Strom, M. and Gallwitz, D., 1999, Primary structure and biochemical characterization of yeast GTPase-activating proteins with substrate preference for the transport GTPase Ypt7p. Eur. J. Biochem., 260, 284290.
- Walch-Solimena, C., Collins, R. N. and Novick, P. J., 1997, Sec2p mediates nucleotide exchange on Sec4p and is involved in polarized delivery of post-Golgi vesicles. J. Cell Biol., 137, 1495-1509.
- Zhu, Z., Delprato, A., Merithew, E. and Lambright, D. G., 2001, Determinants of the broad recognition of exocytic Rab GTPases by Mss4. Biochemistry, 40, 15699-15706.
- Wada, M., Nakanishi, H., Satoh, A., Hirano, H., Obaishi, H., Matsuura, Y. and Takai, Y., 1997, Isolation and characterization of a GDP/GTP exchange protein specific for the Rab3 subfamily small G proteins. J. Biol. Chem., 272, 3875-3878.
- Luo, H. R., Saiardi, A., Nagata, E., Ye, K., Yu, H., Jung, T. S., Luo, X., Jain, S., Sawa, A. and Snyder, S. H., 2001, GRAB: a physiologic guanine nucleotide exchange factor for Rab3A, which interacts with inositol hexakisphosphate kinase. Neuron, 31, 439-451.
- Siniossoglou, S., Peak-Chew, S. Y. and Pelham, H. R., 2000, Rid p and Rgp1p form a complex that catalyses nucleotide exchange on Ypt6p. EMBO J., 19, 4885-4894.
- Horiuchi, H., Lippe, R., McBride, H. M., Rubino, M., Woodman, P., Stenmark, H., Rybin, V., Wilm, M., Ashman, K., Mann, M. and Zerial, M., 1997, A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function. Cell. 90, 1149-1159.
- Hama, H., Tall, G. G. and Horazdovsky, B. F., 1999, Vps9p is a guanine nucleotide exchange factor involved in vesiclemediated vacuolar protein transport. J. Biol. Chem., 274, 15284-15291.
- Tall, G. G., Barbieri, M. A., Stahl, P. D. and Horazdovsky, B. F., 2001, Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1. Dev. Cell, 1, 73-82.
- Wurmser, A. E., Sato, T. K. and Emr, S. D., 2000, New component of the vacuolar class C-Vps complex couples nucleotide exchange on the Ypt7 GTPase to SNARE-dependent docking and fusion. J. Cell Biol., 151, 551-562.
- Hattula, K., Furuhjelm, J., Arffman, A. and Peranen, J., 2002, A Rab8-specffic GDP/GTP exchange factor is involved in actin remodeling and polarized membrane transport. Mol. Biol. Cell, 13, 3268-3280.
- Calera, M., Winand, N. and Collins, R. N., 2002, Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors. FEBS Lett., 515, 89-98.
- Yang, X., Matern, H. T. and Gallwitz, D., 1998, Specific binding to a novel and essential Golgi membrane protein (Yip1p) functionally links the transport GTPases Ypt1p and Ypt31p. EMBO J., 17, 4954-4963.
- Hoffenberg, S., Liu, X., Nikolova, L., Hall, H. S., Dai, W., Baughn, R. E., Dickey, B. F., Barbieri, M. A., Aballay, A., Stahl, P. D. and Knoll, B. J., 2000, A novel membrane-anchored RabS interacting protein required for homotypic endosome fusion. J. Biol. Chem., 275, 24661-24669.
- Brondyk, W. H., McKiernan, C. J., Fortner, K. A., Stabile, P., Holz, R. W. and Macara, I. G., 1995, Interaction cloning of Rabin3, a novel protein that associates with the Ras-like GTPase Rab3A. Mol. Cell Biol., 15, 1137-1143.
- Martincic, I., Peralta, M. E. and Ngsee, J. K., 1997, Isolation and characterization of a dual prenylated Rab and VAMP2 receptor. J. Biol. Chem., 272, 26991-26998.
- Fuiman, C., Short, S. M., Subramanian, R. R., Zetter, B. R. and Roberts, T. M., 2002, DEF-1/ASAP1 is a GTPaseactivating protein (GAP) for ARF1 that enhances cell motility through a GAP-dependent mechanism. J. Biol. Chem., 277, 7962-7969.
- Krugmann, S., Anderson, K. E., Ridley, S. H., Risso, N., McGregor, A., Coadwell, J., Davidson, K., Eguinoa, A., Ellson, C. D., Lipp, P., Manifava, M., Ktistakis, N., Painter, G., Thuring, J. W., Cooper, M. A., Lim, Z. Y., Holmes, A. B., Dove, S. K., Michell, R. H., Grewal, A., Nazarian, A., Erdjument-Bromage, H., Tempst, P., Stephens, L. R. and Hawkins, P. T., 2002, Identification of ARAP3, a novel PI3K effector regulating both Art and Rho GTPases, by selective capture on phosphoinositide affinity matrices. Mol. Cell, 9, 95108.
- Bariowe, C. and Schekman, R., 1993, SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER. Nature, 365, 347-349.
- Meacci, E., Tsai, S. C., Adamik, R., Moss, J. and Vaughan, M., 1997. Cytohesin-1, a cytosolic guanine nucleotide-exchange protein for ADP-ribosylation factor. Proc. Natl. Acad. Sci., USA, 94, 1745-1748.
- Geiger, C., Nagel, W., Boehm, T., van Kooyk, Y., Figdor, C. G., Kremmer, E., Hogg, N., Zeitlmann, L., Dierks, H., Weber, K. S. and Kolanus, W., 2000, Cytohesin-1 regulates beta-2 integrin-mediated adhesion through both ARF-GEF function and interaction with LFA-L EMBO J., 19, 2525-2536.
- Mansour, M., Lee, S. Y. and Pohajdak, B., 2002, The Nterminal coiled coil domain of the cytohesin/ARNO family of guanine nucleotide exchange factors interacts with the scaffolding protein CASP. J. Biol. Chem., 277, 32302-32309.
- Tang, P., Cheng, T. P., Agnello, D., Wu, C. Y., Hissong, B. D., Watford, W. T., Ahn, H. J., Galon, J., Moss, J., Vaughan, M., O'Shea, J. J. and Gadina, M., 2002, Cybr, a cytokine-inducible protein that binds cytohesin-1 and regulates its activity. Proc. Natl. Acad. Sci., USA, 99, 2625-2629.
- Frank, S., Upender, S., Hansen, S. H. and Casanova, J. E., 1998. ARNO is a guanine nucleotide exchange factor for ADPribosylation factor 6. J. Biol. Chem., 273, 23-27.
- Claing, A., Chen, W., Miller, W. E., Vitale, N., Moss, J., Premont, R. T. and Lefkowitz, R. J., 2001, beta-Arrestinmediated ADP-ribosylation factor 6 activation and beta 2adrenergic receptor endocytosis. J. Biol. Chem., 276, 4250942513.
- Jochum, A., Jackson, D., Schwarz, H., Pipkom, R. and SingerKruger, B., 2002, Yeast Ysl2p, homologous to Sec7 domain guanine nucleotide exchange factors, functions in endocytosis and maintenance of vacuole integrity and interacts with the Arf-Like small GTPase Arl1p. Mol. Cell Biol., 22, 4914-4928.
- Togawa, A., Morinaga, N., Ogasawara, M., Moss, J. and Vaughan, M., 1999, Purification and cloning of a brefeldin Ainhibited guanine nucleotide-exchange protein for ADP-ribosylation factors. J. Biol. Chem., 274, 12308-12315.
- Kitano, J., Kimura, K., Yamazaki, Y., Soda, T., Shigemoto, R., Nakajima, Y. and Nakanishi, S., 2002, Tamalin, a PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins. J. Neurosci., 22, 1280-1289.
- Franco, M., Peters, P. J., Boretto, J., van Donselaar, E., Neri, A., D'Souza-Schorey, C. and Chavrier, P., 1999, EFA6, a sec7 domain-containing exchange factor for ARF6, coordinates membrane recycling and actin cytoskeleton organization. EMBO J., 18, 1480-1491.
- Steinmann, T., Geldner, N., Grebe, M., Mangold, S., Jackson, C. L., Paris, S., Galweiler, L., Palme, K. and Jurgens, G., 1999, Coordinated polar localization of auxin efflux carrier PIN1 by GNOM ARF GEF. Science, 286, 316-318.
- Nagai, H., Kagan, J. C., Zhu, X., Kahn, R. A. and Roy, C. R., 2002, A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes. Science, 295, 679-682.
- Donaldson, J. G., Cassel, D., Kahn, R. A. and Klausner, R. D., 1992, ADP-ribosylation factor, a small GTP-binding protein, is required for binding of the coatomer protein beta-COP to Golgi membranes. Proc. Natl. Acad. Sci, USA, 89, 6408-6412.
- Dell'Angelica, E. C., Puertollano, R., Mullins, C., Aguilar, R. C., Vargas, J. D., Hartnell, L. M. and Bonifacino, J. S., 2000, GGAs: a family of ADP ribosylation factor-binding proteins related to adaptors and associated with the Golgi complex. J. CeII Biol., 149, 81-94.
- Singer, W. D., Brown, H. A., Jiang, X. and Sternweis, P. C., 1996, Regulation of phospholipase D by protein kinase C is synergistic with ADP-ribosylation factor and independent of protein kinase activity. J. Biol. Chem., 271, 4504-4510.
- Brown, H. A., Gutowski, S., Moomaw, C. R., Slaughter, C. and Stemweis, P. C., 1993, ADP-ribosylation factor, a small GTPdependent regulatory protein, stimulates phospholipase D activity. Cell, 75, 1137-1144.
- Colombo, M. I., lnglese, J., D'Souza-Schorey, C., Beron, W. and Stahl, P. D., 1995, Heterotrimeric G proteins interact with the small GTPase ARF. Possibilities for the regulation of vesicular traffic. J. Biol. Chem., 270, 24564-24571.
- Boehm, M., Aguilar, R. C. and Bonifacino, J. S., 2001, Functional and physical interactions of the adaptor protein complex AP-4 with ADP-ribosylation factors (ARFs). EMBO J., 20, 6265-6276.
- Kanon, H., Williger, B. T. and Exton, J. H., 1997, Arfaptin 1, a putative cytosolic target protein of ADP-ribosylation factor, is recruited to Golgi membranes. J. Biol. Chem., 272, 54215429.
- Peters, P. J., Ning, K., Palacios, F., Boshans, R. L., Kazantsev, A., Thompson, L. M., Woodman, B., Bates, G. P. and D'Souza-Schorey, C., 2002, Arfaptin 2 regulates the aggregation of mutant huntingtin protein. Nat. Cell Biol., 4, 240-245.
- Shin, O. H., Ross, A. H., Mihai, I. and Exton, J. H., 1999, Identification of arfophilin, a target protein for GTP-bound class Il ADP-ribosylation factors. J. Biol. Chem., 274, 3660936615.
- Takeya, R., Takeshige, K. and Sumimoto, H., 2000, Interaction of the PDZ domain of human PICK1 with class I ADPribosylation factors. Biochem. Biophys. Res. Commun., 267, 149-155.
- Sharer, J. D. and Kahn, R. A., 1999, The ARF-like 2 (ARL2)binding protein, BART. Purification, cloning, and initial characterization. J. Biol. Chem., 274, 27553-27561.
- Boman, A. L., Kuai, J., Zhu, X., Chen, J., Kuriyama, R. and Kahn, R. A., 1999, Arf proteins bind to mitotic kinesin-like protein 1 (MKLP1) in a GTP-dependent fashion. Cell Motil. Cytoskeleton, 44, 119-132.
- Kahn, R. A. and Gilman, A. G., 1986, The protein cofactor necessary for ADP-ribosylation of Gs by cholera toxin is itself a GTP binding protein. J. Biol. Chem., 261, 7906-7911.
- Jones, D. H., Morris, J. B., Morgan, C. P., Kondo, H., Irvine, R. F. and Cockcroft, S., 2000, Type I phosphatidylinositol 4phosphate 5-kinase directly interacts with ADP-ribosylation factor 1 and is responsible for phosphatidylinositol 4,5-bisphosphate synthesis in the Golgi compartment. J. Biol. Chem., 275, 13962-13966.
- Honda, A., Nogami, M., Yokozeki, T., Yamazaki, M., Nakamura, H., Watanabe, H., Kawamoto, K., Nakayama, K., Morris, A. J., Frohman, M. A. and Kanaho, Y., 1999, Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formation. Cell, 99, 521-532.
- Linari, M., Hanzal-Bayer, M. and Becker, J., 1999, The delta subunit of rod specific cyclic GMP phosphodiesterase, PDE delta, interacts with the Arf-like protein Arl3 in a GTP specific manner. FEBS Lett., 458, 55-59.
- Van Valkenburgh, H., Shern, J. F., Sharer, J. D., Zhu, X. and Kahn, R. A., 2001, ADP-ribosylation factors (ARFs) and ARFlike 1 (ARL1) have both specific and shared effectors: characterizing ARL1-binding proteins. J. Biol. Chem., 276, 22826-22837.
- lngley, E., Williams, J. H., Walker, C. E., Tsai, S., Colley, S., Sayer, M. S., Tilbrook, P. A., Sarna, M., Beaumont, J. G. and Klinken, S. P., 1999, A novel ADP-ribosylation like factor (ARL6), interacts with the protein-conducting channel SEC61beta subunit. FEBS Lett., 459, 69-74.
- Mossessova, E., Gulbis, J. M. and Goldberg, J., 1998, Structure of the guanine nucleotide exchange factor Sec7 domain of human ARNO and analysis of the interaction with ARF GTPase. Cell, 92, 415-423.
Free access
Rab and ARF GTPase regulation of exocytosis (Review)
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.