Structural and functional characterization of the human NBC3 sodium/bicarbonate co-transporter carboxyl-terminal cytoplasmic domain

References

• Abuladze, N., Lee, I., Newman, D., Hwang, J., Boorer, K., Pushkin, A. and Kurtz, I., 1998, Molecular cloning, chromosomal localization, tissue distribution, and functional expression of the human pancreatic sodium bicarbonate cotransporter. Journal of Biological Chemistry, 273, 17689–17695.
   PubMed Web of Science ®Google Scholar
• Alper, S. L, Chernova, M. N. and Stewart, A. K., 2001, Regulation of Na+-independent Cl^/HCO^ exchangers by pH. Journal of Pancreas, 2, 171–175.
   Google Scholar
• Amlal, H., Burnham, C. E. and Soleimani, M., 1999, Characterization of Na+/HCO3T cotransporter isoform NBC-3 [published erratum appears in American Journal of Physiology, 1999; 277: following table of contents]. American Journal of Physiology, 276, F903–F913.
   PubMedGoogle Scholar
• Avkiran, M. and Haworth, R. S., 1999, Regulation of cardiac sarcolemmal Na+/H+ exchanger activity by endogenous ligands. Relevance to ischemia. Annals of the New York Academy of Science, 874, 335–345.
   PubMed Web of Science ®Google Scholar
• Bevensee, M. O., Schmitt, B. M., Choi, I., Romero, M. F. and Boron, W. F., 2000, An electrogenic Na + -HCO3T cotransporter (NBC) with a novel COOH-terminus, cloned from rat brain. American Journal of Physiology, 278, C1200–C1211.
   Google Scholar
• Boron, V. F., Hediger, M. A., Boulpaep, E. L. and Romero, M. F., 1997, The renal electrogenic Na+: HCO3Tcotransporter. Journal of Experimental Biology, 200, 263–268.
   PubMed Web of Science ®Google Scholar
• Bradford, M. M., 1976, Arapid and sensitive method for the quantitation of microgram quantities of protein utilizing the pricinple of protein-dye binding. Analytical Biochemistry, 72, 248–254.
   PubMed Web of Science ®Google Scholar
• Burnham, C. E., Flagella, M., Wang, Z., Amlal, H., Shull, G. E. and Soleimani, M., 1998, Cloning, renal distribution, and regulation of the rat Na+-HCO3T cotransporter. American Journal of Physiology, 274, F1119–F1126.
   PubMedGoogle Scholar
• Choi, I., Romero, M. F., Khandoudi, N., Bril, A. and Boron, W. F., 1999, Cloning and characterization of a human electrogenic Na+-HCO3T cotransporter isoform (hhNBC). American Journal of Physiology, 276, C576–C584.
   PubMed Web of Science ®Google Scholar
• Choi, I., Aalkjaer, C, Boulpaep, E. L. and Boron, W. F., 2000, An electroneutral sodium/bicarbonate cotransporter NBCn1 and associated sodium channel. Nature, 405, 571–575.
   PubMed Web of Science ®Google Scholar
• Chow, C. W., 1999, Regulation and intracellular localization of the epithelial isoforms of the Na+/H+ exchangers NHE2 and NHE3. Clinical Investigations in Medicine, 22, 195–206.
   PubMed Web of Science ®Google Scholar
• Gross, E. and Hopfer, U., 1999, Effects of pH on kinetic parameters of the Na+/HCO3T cotransporter in renal proximal tubule. Biophysics Journal, 76, 3066–3075.
   PubMed Web of Science ®Google Scholar
• Gross, E., Abuladze, N., Pushkin, A., Kurtz, I. and Cotton, C. U., 2001, The stoichiometry of the electrogenic sodium bicarbonatecotransporter pNBC1 in mouse pancreatic duct cells is 2 HCO^:1Na + . Journal of Physiology, 531, 375–382.
   Google Scholar
• Gross, E., Pushkin, A., Abuladze, N., Fedotoff, O. and Kurtz, I., 2002, Regulation of the sodium bicarbonate cotransporter kNBC1function: role of Asp(986), Asp(988) and kNBC1-carbonic anhy-drase II binding. Journal of Physiology, 544, 679–685.
   PubMed Web of Science ®Google Scholar
• Hara, C, Satoh, H., Usui, T., Kunimi, M., Noiri, E., Tsukamoto, K., Taniguchi, S., Uwatoko, S., Goto, A., Racusen, L. C, Inatomi, J., Endou, H., Fujita, T. and Seki, G., 2003, Intracellular pH regulatory mechanism in a human renal proximal cell line (HKC-8): evidence for Na+/H+ exchanger, Cl^/HCO^ exchanger and Na+/HCO3T cotransporter. Pflugers Archives, 440, 713–720.
   Google Scholar
• Hume, J. R., Duan, D., Collier, M. L, Yamazaki, J. and Horowitz, B., 2000, Anion transport in heart. Physiology Reviews, 80, 31–81.
   PubMed Web of Science ®Google Scholar
• Igarashi, P., Reilly, R. F., Hildebrandt, F., Biemesderfer, D., Reboucas, N. A., Slayman, C. W. and Aronson, P. S., 1991, Molecular biology of renal Na+/H+ exchangers. Kidney International Supplement, 33, S84–S89.
   PubMedGoogle Scholar
• Juel, C, 1996, Lactate/proton co-transport in skeletal muscle: regulation and importance for pH homeostasis. Acta Physiologica Scandinavia, 156, 369–374.
   PubMedGoogle Scholar
• Khandoudi, N., Albadine, J., Robert, P., Krief, S., Berrebi-Bertrand, I., Martin, X., Bevensee, M. O., Boron, W. F. and Bril, A., 2001, Inhibition of the cardiac electrogenic sodium bicarbonate cotransporter reduces ischemic injury. Cardiovascular Research, 52, 387–396.
   PubMed Web of Science ®Google Scholar
• Kim, J. H., Lee-Kwon, W., Park, J. B., Ryu, S. H., Yun, C. H. and Donowitz, M., 2002, Ca2+-dependent inhibition of Na+/H + exchanger 3 (NHE3) requires an NHE3-E3KARP-alpha-actinin-4 complex for oligomerization and exmlytosis. Journal of Biological Chemistry, 277, 23714–23724.
   PubMed Web of Science ®Google Scholar
• Komukai, K., Ishikawa, T. and Kurihara, S., 1998, Effects of acidosis on Ca2+ sensitivity of contractile elements in intact ferret myocardium. American Journal of Physiology, 274, H147–H54.
   PubMedGoogle Scholar
• Kwon, T. H., Pushkin, A., Abuladze, N., Nielsen, S. and Kurtz, I., 2000, Immunoelectron microscopic localization of NBC3 sodium-bicarbonate cotransporter in rat kidney. American Journal of Physiology Renal Physiology, 278, F327–F336.
   PubMed Web of Science ®Google Scholar
• Laemmli, U. K., 1970, Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature, 227, 680–685.
   PubMed Web of Science ®Google Scholar
• Laue, T. M. and Stafford 3rd, W. F., 1999, Modern applications of analytical ultracentrifugation. Annual Review of Biophysics and Biomolecular Structures, 28, 75–100.
   Google Scholar
• Leviel, F., Eladari, D., Blanchard, A., Poumarat, J. S., Paillard, M. and Podevin, R. A., 1999, Pathways for HCO^ exit across the basolateral membrane in rat thick limbs. American Journal of Physiology, 276, F847-F856.
   Google Scholar
• Lieberman, D. M. and Reithmeier, R. A. F., 1988, Localization of the carboxyl terminus of Band 3 to the cytoplasmic side of the erythrocyte membrane using antibodies raised against a synthetic peptide. Journal of Biological Chemistry, 263, 10022–10028.
   PubMed Web of Science ®Google Scholar
• Lubman, R. L. and Crandall, E. D., 1992, Regulation of intracellular pH in alveolar epithelial cells. American Journal of Physiology, 262, L1–L14.
   PubMed Web of Science ®Google Scholar
• Park, M., Ko, S. B., Choi, J. Y., Muallem, G., Thomas, P. J., Pushkin, A., Lee, M. S., Kim, J. Y., Lee, M. G., Muallem, S. and Kurtz, I., 2002, The cystic fibrosis transmembrane conductance regulator interacts with and regulates the activity of the HCO3T salvage transporter human Na+ -HCO^ cotransport isoform 3. Journal of Biological Chemistry, 277, 50503–50509.
   Google Scholar
• Philo, J. S., 1997, An improved function for fitting sedimentation velocity data for low-molecular-weight solutes. Biophysics Journal, 72, 435–444.
   PubMed Web of Science ®Google Scholar
• Provencher, S. W. and Glockner, J., 1981, Estimation of globular protein secondary structure from circular dichroism. Biochemistry, 20, 33–37.
   PubMed Web of Science ®Google Scholar
• Pushkin, A., Abuladze, N., Lee, I., Newman, D., Hwang, J. and Kurtz, I., 1999, Cloning, tissue distribution, genomic organization, and functional characterization of NBC3, a new member of the sodium bicarbonate cotransporter family. Journal of Biological Chemistry, 274, 16569–16575.
   PubMed Web of Science ®Google Scholar
• Pushkin, A., Yip, K. P., Clark, I., Abuladze, N., Kwon, T. H., Tsuruoka, S., Schwartz, G. J., Nielsen, S. and Kurtz, I., 1999, NBC3 expression in rabbit collecting duct: colocalization with vacuolar H + -ATPase. American Journal of Physiology, 277, F974–F981.
   PubMedGoogle Scholar
• Pushkin, A., Abuladze, N., Newman, D., Lee, I., Xu, G. and Kurtz, I., 2000, Two C-terminal variants of NBC4, a new member of the sodium bicarbonate cotransporter family: cloning, characterization, and localization. IUBMB Life, 50, 13–19.
   PubMed Web of Science ®Google Scholar
• Pushkin, A., Abuladze, N., Newman, D., Lee, I., Xu, G. and Kurtz, I., 2000, Cloning, characterization and chromosomal assignment of NBC4, a new member of the sodium bicarbonate cotransporter family. Biochimica et Biophysica Acta, 1493, 215–218.
   PubMedGoogle Scholar
• Romero, M. F., Hediger, M. A., Boulpaep, E. L. and Boron, W. F., 1997, Expression cloning and characterization of a renal electrogenic Na+/HCO3T cotransporter. Nature, 387, 409–413.
   PubMed Web of Science ®Google Scholar
• Romero, M. F., Fong, P., Berger, U. V., Hediger, M. A. and Boron, W. F., 1998, Cloning and functional expression of rNBC, an electrogenic Na + -HCO3T cotransporter from rat kidney. American Journal of Physiology, 274, F425–F432.
   PubMedGoogle Scholar
• Roos, A. and Boron, W. F., 1981, Intracellular pH. Physiology Review, 61, 296–434.
   PubMed Web of Science ®Google Scholar
• Ruetz, S., Lindsey, A. E. and Kopito, R. R., 1993, Function and biosynthesis of erythroid and nonerythroid anion exchangers. Society of General Physiologists Series, 48, 193–200.
   PubMedGoogle Scholar
• Sassani, P., Pushkin, A., Gross, E., Gomer, A., Abuladze, N., Dukkipati, R., Carpenito, G. and Kurtz, I., 2002, Functional characterization of NBC4: a new electrogenic sodium-bicarbonate cotransporter. American Journal of Physiology and Cell Physiology, 282, C408–416.
   PubMed Web of Science ®Google Scholar
• Sherman, M. and Goldberg, A. L., 1992, Involvement of the chaperonin dnaK in the rapid degradation of a mutant protein in Escherichia coli. Embo Journal, 11, 71–77.
   PubMed Web of Science ®Google Scholar
• Sterling, D. and Casey, J. R., 1999, Transport activity of AE3 chloride/bicarbonate anion-exchange proteins and their regulation by intracellular pH. Biochemistry Journal, 344, 221–229.
   PubMed Web of Science ®Google Scholar
• Sterling, D. and Casey, J. R., 2002, Bicarbonate transport proteins. Biochemistry and Cell Biology, 80, 483–497.
   PubMedGoogle Scholar
• Sterling, D., Reithmeier, R. A. and Casey, J. R., 2001, Carbonic anhydrase: in the driver’s seat for bicarbonate transport. Journal of Pancreas, 2, 165–170.
   PubMedGoogle Scholar
• Sterling, D., Reithmeier, R. A. and Casey, J. R., 2001, A transport metabolon: Functional interaction of carbonic anhydrase II and chloride/bicarbonate exchangers. Journal of Biological Chemistry, 17, 17.
   Google Scholar
• Thevenod, F., Roussa, E., Schmitt, B. M. and Romero, M. F., 1999, Cloning and immunolocalization of a rat pancreatic Na+ bicarbonate cotransporter. Biochemical and Biophysics Research Communications, 264, 291–298.
   PubMed Web of Science ®Google Scholar
• Thomas, J. A., Buchsbaum, R. N., Zimniak, A. and Racker, E., 1979, Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ. Biochemistry, 18, 2210–2218.
   PubMed Web of Science ®Google Scholar
• Towbin, H., Staehelin, T. and Gordon, J., 1979, Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proceeding of the National Academy of Sciences (USA), 76, 4350–4354.
   PubMed Web of Science ®Google Scholar
• Turner, H. C, Alvarez, L. J. and Candia, O. A., 2001, Identification and localization of acid-base transporters in the conjunctival epithelium. Experimental Eye Research, 72, 519–531.
   PubMed Web of Science ®Google Scholar
• Wang, Z., Conforti, L., Petrovic, S., Amlal, H., Burnham, C. E. and Soleimani, M., 2001, Mouse Na+: HCO3Tcotransporter isoform NBC-3 (kNBC-3): cloning, expression, and renal distribution. Kidney International, 59, 1405–1414.
   PubMed Web of Science ®Google Scholar
• Weinman, E. J., Evangelista, C. M., Steplock, D., Liu, M. Z., Shenolikar, S. and Bernardo, A., 2001, Essential role for NHERF in cAMP-mediated inhibition of the Na+/HCO3T co-transporter in BSC-1 cells. Journal of Biological Chemistry, 276, 42339–42346.
   PubMed Web of Science ®Google Scholar
• Zhang, D., Kiyatkin, A., Bolin, J. T. and Low, P. S., 2000, Crystal-lographic structure and functional interpretation of the cytoplasmic domain of erythrocyte membrane band 3. Blood, 96, 2925–2933.
   PubMed Web of Science ®Google Scholar
• Zhu, Q., Lee, D. W. K. and Casey, J. R., 2003, Novel topology in C-terminal region of the human plasma membrane anion exchanger, AE1. Journal of Biological Chemistry, 278, 112–120.
   Web of Science ®Google Scholar