Gene expression profiling, chromosome assignment and mutational analysis of the porcine Golgi-resident UDP-N-Acetylglucosamine transporter SLC35A3

References

• Abe M, Hashimoto H, Yoda K. Molecular characterization of Vig4/Vrg4 GDP-mannose transporter of the yeast Saccharomyces cerevisiae. FEBS Lett 1999; 458: 309–312
   PubMedGoogle Scholar
• Abeijon C, Robbins PW, Hirschberg CB. Molecular cloning of the Golgi apparatus uridine diphosphate-N-acetylglucosamine transporter from Kluyveromyces lactis. Proc Natl Acad Sci USA 1996; 93: 5963–5968
   PubMedGoogle Scholar
• Aoki K, Ishida N, Kawakita M. Substrate recognition by UDP-galactose and CMP-sialic acid transporters. Different sets of transmembrane helices are utilized for the specific recognition of UDP-galactose and CMP-sialic acid. J Biol Chem 2001; 276: 21555–21561
   PubMed Web of Science ®Google Scholar
• Aoki K, Ishida N, Kawakita M. Substrate recognition by nucleotide sugar transporters: further characterization of substrate recognition regions by analyses of UDP-galactose/CMP-sialic acid transporter chimeras and biochemical analysis of the substrate specificity of parental and chimeric transporters. J Biol Chem 2003; 278: 22887–22893
   PubMed Web of Science ®Google Scholar
• Aoki K, Sun-Wada GH, Segawa H, Yoshioka S, Ishida N, Kawakita M. Expression and activity of chimeric molecules between human UDP-galactose transporter and CMP-sialic acid transporter. J Biochem (Tokyo) 1999; 126: 940–950
   PubMedGoogle Scholar
• Berninsone PM, Hirschberg CB. Nucleotide sugar transporters of the Golgi apparatus. Curr Opin Struct Biol 2000; 10: 542–547
   PubMed Web of Science ®Google Scholar
• Caffaro CE, Hirschberg CB, Berninsone PM. Independent and simultaneous translocation of two substrates by a nucleotide sugar transporter. Proc Natl Acad Sci USA 2006; 103: 16176–16181
   PubMedGoogle Scholar
• Capasso JM, Hirschberg CB. Mechanisms of glycosylation and sulfation in the Golgi apparatus: evidence for nucleotide sugar/nucleoside monophosphate and nucleotide sulfate/nucleoside monophosphate antiports in the Golgi apparatus membrane. Proc Natl Acad Sci USA 1984; 81: 7051–7055
   PubMed Web of Science ®Google Scholar
• Chevalet C, Gouzy J, SanCristobal-Gaudy M. Regional assignment of genetic markers using a somatic cell hybrid panel: a WWW interactive program available for the pig genome. Comput Appl Biosci 1997; 13: 69–73
   PubMedGoogle Scholar
• Dean N, Zhang YB, Poster JB. The VRG4 gene is required for GDP-mannose transport into the lumen of the Golgi in the yeast, Saccharomyces cerevisiae. J Biol Chem 1997; 272: 31908–31914
   PubMedGoogle Scholar
• Eckhardt M, Gotza B, Gerardy-Schahn R. Mutants of the CMP-sialic acid transporter causing the Lec2 phenotype. J Biol Chem 1998; 273: 20189–20195
   PubMed Web of Science ®Google Scholar
• Eckhardt M, Gotza B, Gerardy-Schahn R. Membrane topology of the mammalian CMP-sialic acid transporter. J Biol Chem 1999; 274: 8779–8787
   PubMedGoogle Scholar
• Eckhardt M, Muhlenhoff M, Bethe A, Gerardy-Schahn R. Expression cloning of the Golgi CMP-sialic acid transporter. Proc Natl Acad Sci USA 1996; 93: 7572–7576
   PubMed Web of Science ®Google Scholar
• Freeze HH. Genetic defects in the human glycome. Nat Rev Genet 2006; 7: 537–551
   PubMed Web of Science ®Google Scholar
• Fujishima-Kanaya N, Toki D, Suzuki K, Sawazaki T, Hiraiwa H, Iida M, Hayashi T, Uenishi H, Wada Y, Ito Y, Awata T. Development of 50 gene-associated microsatellite markers using BAC clones and the construction of a linkage map of swine chromosome 4. Anim Genet 2003; 34: 135–141
   PubMedGoogle Scholar
• Gao XD, Dean N. Distinct protein domains of the yeast Golgi GDP-mannose transporter mediate oligomer assembly and export from the endoplasmic reticulum. J Biol Chem 2000; 275: 17718–17727
   PubMedGoogle Scholar
• Gao XD, Nishikawa A, Dean N. Identification of a conserved motif in the yeast golgi GDP-mannose transporter required for binding to nucleotide sugar. J Biol Chem 2001; 276: 4424–4432
   PubMedGoogle Scholar
• Gietz RD, Woods RA. Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method. Methods Enzymol 2002; 350: 87–96
   PubMed Web of Science ®Google Scholar
• Gorodkin J, Cirera S, Hedegaard J, Gilchrist MJ, Panitz F, Jorgensen CB, Scheibye-Knudsen K, Arvin T, Lumholdt S, Sawera M, Green T, Nielsen BJ, Havgaard JH, Rosenkilde C, Wang J, Li H, Li R, Liu B, Hu S, Dong W, Li W, Yu J, Wang J, Staerfeltd HH, Wernersson R, Madsen LB, Thomsen B, Hornshoj H, Bujie Z, Wang X, Wang X, Bolund L, Brunak S, Yang H, Bendixen C, Fredholm M. Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 ESTs. Genome Biol. 2007; 2; 8: R45
   Google Scholar
• Guillen E, Abeijon C, Hirschberg CB. Mammalian Golgi apparatus UDP-N-acetylglucosamine transporter: molecular cloning by phenotypic correction of a yeast mutant. Proc Natl Acad Sci USA 1998; 95: 7888–7892
   PubMedGoogle Scholar
• Helmus Y, Denecke J, Yakubenia S, Robinson P, Luhn K, Watson DL, McGrogan PJ, Vestweber D, Marquardt T, Wild MK. Leukocyte adhesion deficiency II patients with a dual defect of the GDP-fucose transporter. Blood 2006; 107: 3959–3966
   PubMedGoogle Scholar
• Hiraiwa H, Sawazaki T, Suzuki K, Fujishima-Kanaya N, Toki D, Ito Y, Uenishi H, Hayashi T, Awata T, Yasue H. Elucidation of correspondence between swine chromosome 4 and human chromosome 1 by assigning 27 genes to the ImpRH map, and development of microsatellites in the proximity of 14 genes. Cytogenet Genome Res 2003; 101: 84–89
   PubMedGoogle Scholar
• Hirschberg CB, Robbins PW, Abeijon C. Transporters of nucleotide sugars, ATP, and nucleotide sulfate in the endoplasmic reticulum and Golgi apparatus. Annu Rev Biochem 1998; 67: 49–69
   PubMed Web of Science ®Google Scholar
• Hoflich J, Berninsone P, Gobel C, Gravato-Nobre MJ, Libby BJ, Darby C, Politz SM, Hodgkin J, Hirschberg CB, Baumeister R. Loss of srf-3-encoded nucleotide sugar transporter activity in Caenorhabditis elegans alters surface antigenicity and prevents bacterial adherence. J Biol Chem 2004; 279: 30440–30448
   Google Scholar
• Hong K, Ma D, Beverley SM, Turco SJ. The Leishmania GDP-mannose transporter is an autonomous, multi-specific, hexameric complex of LPG2 subunits. Biochemistry 2000; 39: 2013–2022
   PubMedGoogle Scholar
• Ishida N, Kawakita M. Molecular physiology and pathology of the nucleotide sugar transporter family (SLC35). Pflugers Arch 2004; 447: 768–775
   PubMed Web of Science ®Google Scholar
• Ishida N, Miura N, Yoshioka S, Kawakita M. Molecular cloning and characterization of a novel isoform of the human UDP-galactose transporter, and of related complementary DNAs belonging to the nucleotide-sugar transporter gene family. J Biochem (Tokyo) 1996; 120: 1074–1078
   PubMedGoogle Scholar
• Ishida N, Yoshioka S, Chiba Y, Takeuchi M, Kawakita M. Molecular cloning and functional expression of the human Golgi UDP-N-acetylglucosamine transporter. J Biochem (Tokyo) 1999a; 126: 68–77
   PubMedGoogle Scholar
• Ishida N, Yoshioka S, Iida M, Sudo K, Miura N, Aoki K, Kawakita M. Indispensability of transmembrane domains of Golgi UDP-galactose transporter as revealed by analysis of genetic defects in UDP-galactose transporter-deficient murine had-1 mutant cell lines and construction of deletion mutants. J Biochem (Tokyo) 1999b; 126: 1107–1117
   PubMedGoogle Scholar
• Kyte J, Doolittle RF. A simple method for displaying the hydropathic character of a protein. J Mol Biol 1982; 157: 105–132
   PubMed Web of Science ®Google Scholar
• Lubke T, Marquardt T, Etzioni A, Hartmann E, von Figura K, Korner C. Complementation cloning identifies CDG-IIc, a new type of congenital disorders of glycosylation, as a GDP-fucose transporter deficiency. Nat Genet 2001; 28: 73–76
   PubMed Web of Science ®Google Scholar
• Luhn K, Wild MK, Eckhardt M, Gerardy-Schahn R, Vestweber D. The gene defective in leukocyte adhesion deficiency II encodes a putative GDP-fucose transporter. Nat Genet 2001; 28: 69–72
   PubMed Web of Science ®Google Scholar
• Ma D, Russell DG, Beverley SM, Turco SJ. Golgi GDP-mannose uptake requires Leishmania LPG2. A member of a eukaryotic family of putative nucleotide-sugar transporters. J Biol Chem 1997; 272: 3799–3805
   PubMedGoogle Scholar
• Martinez-Duncker I, Dupre T, Piller V, Piller F, Candelier JJ, Trichet C, Tchernia G, Oriol R, Mollicone R. Genetic complementation reveals a novel human congenital disorder of glycosylation of type II, due to inactivation of the Golgi CMP-sialic acid transporter. Blood 2005; 105: 2671–2676
   PubMed Web of Science ®Google Scholar
• Martinez-Duncker I, Mollicone R, Codogno P, Oriol R. The nucleotide-sugar transporter family: a phylogenetic approach. Biochimie 2003; 85: 245–260
   PubMedGoogle Scholar
• Miura N, Ishida N, Hoshino M, Yamauchi M, Hara T, Ayusawa D, Kawakita M. Human UDP-galactose translocator: molecular cloning of a complementary DNA that complements the genetic defect of a mutant cell line deficient in UDP-galactose translocator. J Biochem (Tokyo) 1996; 120: 236–241
   PubMedGoogle Scholar
• Moller M, Berg F, Riquet J, Pomp D, Archibald A, Anderson S, Feve K, Zhang Y, Rothschild M, Milan D, Andersson L, Tuggle CK. High-resolution comparative mapping of pig Chromosome 4, emphasizing the FAT1 region. Mamm Genome 2004; 15: 717–731
   PubMedGoogle Scholar
• Oelmann S, Stanley P, Gerardy-Schahn R. Point mutations identified in Lec8 Chinese hamster ovary glycosylation mutants that inactivate both the UDP-galactose and CMP-sialic acid transporters. J Biol Chem 2001; 276: 26291–26300
   PubMed Web of Science ®Google Scholar
• Puglielli L, Hirschberg CB. Reconstitution, identification, and purification of the rat liver golgi membrane GDP-fucose transporter. J Biol Chem 1999; 274: 35596–35600
   PubMedGoogle Scholar
• Puglielli L, Mandon EC, Rancour DM, Menon AK, Hirschberg CB. Identification and purification of the rat liver Golgi membrane UDP-N-acetylgalactosamine transporter. J Biol Chem 1999; 274: 4474–4479
   PubMedGoogle Scholar
• Segawa H, Ishida N, Takegawa K, Kawakita M. Schizosaccharomyces pombe UDP-galactose transporter: identification of its functional form through cDNA cloning and expression in mammalian cells. FEBS Lett 1999; 451: 295–298
   PubMedGoogle Scholar
• Segawa H, Kawakita M, Ishida N. Human and Drosophila UDP-galactose transporters transport UDP-N-acetylgalactosamine in addition to UDP-galactose. Eur J Biochem 2002; 269: 128–138
   PubMedGoogle Scholar
• Senes A, Engel DE, DeGrado WF. Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifs. Curr Opin Struct Biol 2004; 14: 465–479
   PubMed Web of Science ®Google Scholar
• Suda T, Kamiyama S, Suzuki M, Kikuchi N, Nakayama K, Narimatsu H, Jigami Y, Aoki T, Nishihara S. Molecular cloning and characterization of a human multisubstrate specific nucleotide-sugar transporter homologous to Drosophila fringe connection. J Biol Chem 2004; 279: 26469–26474
   PubMedGoogle Scholar
• Thomsen B, Horn P, Panitz F, Bendixen E, Petersen AH, Holm LE, Nielsen VH, Agerholm JS, Arnbjerg J, Bendixen C. A missense mutation in the bovine SLC35A3 gene, encoding a UDP-N-acetylglucosamine transporter, causes complex vertebral malformation. Genome Res 2006; 16: 97–105
   PubMed Web of Science ®Google Scholar
• Tusnady GE, Simon I. Principles governing amino acid composition of integral membrane proteins: application to topology prediction. J Mol Biol 1998; 283: 489–506
   PubMed Web of Science ®Google Scholar
• Tusnady GE, Simon I. The HMMTOP transmembrane topology prediction server. Bioinformatics 2001; 17: 849–850
   PubMed Web of Science ®Google Scholar
• Waldman BC, Rudnick G. UDP-GlcNAc transport across the Golgi membrane: electroneutral exchange for dianionic UMP. Biochemistry 1990; 29: 44–52
   PubMedGoogle Scholar
• Wernersson R, Schierup MH, Jorgensen FG, Gorodkin J, Panitz F, Staerfeldt HH, Christensen OF, Mailund T, Hornshoj H, Klein A, Wang J, Liu B, Hu S, Dong W, Li W, Wong GK, Yu J, Wang J, Bendixen C, Fredholm M, Brunak S, Yang H, Bolund L. Pigs in sequence space: a 0.66X coverage pig genome survey based on shotgun sequencing. BMC Genomics 2005; 6: 70
   PubMed Web of Science ®Google Scholar
• Yerle M, Echard G, Robic A, Mairal A, Dubut-Fontana C, Riquet J, Pinton P, Milan D, Lahbib-Mansais Y, Gellin J. A somatic cell hybrid panel for pig regional gene mapping characterized by molecular cytogenetics. Cytogenet Cell Genet 1996; 73: 194–202
   PubMedGoogle Scholar
• Yakubenia S, Wild MK. Leukocyte adhesion deficiency II. Advances and open questions. FEBS J 2006; 273: 4390–4398
   PubMedGoogle Scholar