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PAPERS

Length-dependent regulation of the Kv1.2 channel activation by its C-terminus

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Pages 186-193 | Received 12 Sep 2008, Published online: 09 Jul 2009

References

  • Yellen G. The moving parts of voltage-gated ion channels. Quart Rev Biophys 1998; 31: 239–295
  • Long SB, Campbell EB, MacKinnon R. Crystal structure of a mammalian voltage-dependent Shaker Family K+ Channel. Science 2005; 309: 897–903
  • Long SB, Campbell EB, MacKinnon R. Voltage sensor of Kv1.2: structure basis of electromechanical coupling. Science 2005; 309: 903–908
  • VanDongen AM, Frech GC, Drewe JA, Joho RH, Brown AM. Alteration and restoration of K+ channel function by deletions at the N- and C-termini. Neuron 1990; 5: 433–443
  • Marten I, Hoshi T. Voltage-dependent gating characteristics of the K+ channel KAT1 depend on the N and C termini. Proc Natl Acad Sci USA 1997; 94: 3448–3453
  • Aydar E, Palmer C. Functional characterization of the C-terminus of the human ether-a-go-go-related gene K+ channel (HERG). J Physiol (London) 2001; 534: 1–14
  • Loukin SH, Lin J, Athar U, Palmer C, Saimi Y. The carboxyl tail forms a discrete functional domain that blocks closure of the yeast K+ channel. Proc Natl Acad Sci USA 2002; 99: 1926–1930
  • Hatano N, Ohya S, Muraki K, Clark RB, Giles WR, Imaizumi Y. Two arginines in the cytoplasmic C-terminal domain are essential for voltage-dependent regulation of A-type K+ current in the Kv4 channel subfamily. J Biol Chem 2004; 279: 5450–5459
  • Ju M, Stevens L, Leadbitter E, Wray D. The roles of N- and C-terminal determinants in the activation of the Kv2.1 potassium channel. J Biol Chem 2003; 278: 12769–12778
  • Peng K, Radivojac P, Vucetic S, Dunker AK, Obradovic Z. Length-dependent prediction of protein intrinsic disorder. BMC Bioinformatics. 2006; 7: 208–225
  • Dosztanyi Z, Csizmok V, Tompa P, Simon I. IUPred: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content. Bioinformatics 2005; 21: 3433–3434
  • Prilusky J, Felder CE, Zeev-Ben-Mordehai T, Rydberg EH, Man O, Beckmann JS, Silman I, Sussman JL. FoldIndex: a simple tool to predict whether a given protein sequence is intrinsically unfolded. Bioinformatics 2005; 21: 3435–3438
  • Linding R, Russell RB, Neduva V, Gibson TJ. GlobPlot: exploring protein sequences for globularity and disorder Nucleic Acids Res 2003; 31: 3701–3708
  • Berman HM, Westbrook J, Feng Z, Gilliland G., Bhat TN, Weissig H, Shindyalov IN, Bourne PE. The Protein Data Bank. Nucleic Acids Res 2000; 28: 235–242
  • MacKerell AD, Jr, Zhao L, Wu A, Bi L, Liu P, Zhang X, Jiang T, et al. All-atom empirical potential for molecular modeling and dynamics Studies of proteins. J Phys Chem B 1998; 102: 3586–3616
  • Yang JS, Chen WW, Skolnick J, Shakhnovich EI. All-atom ab initio folding of a diverse set of proteins. Structure 2007; 15: 53–63
  • Rohl CA, Strauss CE, Misura KM, Baker D. Protein structure prediction using Rosetta. Methods Enzymol 2004; 383: 66–93
  • Li YJ, Bi LJ, Zhang XE, Zhou YF, Zhang JB, Chen YY, Li W, Zhang ZP. Reversible immobilization of proteins with streptavidin affinity tags on a surface plasmon resonance biosensor chip. Anal Bioanal Chem 2006; 386: 1321–1326
  • Long SB, Tao X, Campbell EB, Mackinnon R. Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment. Nature 2007; 450: 376–382
  • Magidovich E, Fleishman SJ, Yifrach O. Intrinsically disordered C-terminal segments of voltage-activated potassium channels: a possible fishing rod-like mechanism for channel binding to scaffold proteins. Bioinformatics 2006; 22: 1546–1550
  • Magidovich E, Orr I, Fass D, Abdu U, Yifrach O. Intrinsic disorder in the C-terminal domain of the Shaker voltage-activated K+ channel modulates its interaction with scaffold proteins. Proc Natl Acad Sci USA 2007; 104: 13022–13027
  • Doyle DA, Cabral JM, Pfuetzner RA, Kuo A, Gulbis JM, Cohen SL, Chait BT, MacKinnon R. The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science 1998; 280: 69–76
  • Dyson HJ, Wright PE. Intrinsically unstructured proteins and their functions. Nat Rev Mol Cell Biol 2005; 6: 197–208
  • Fink AL. Natively unfolded proteins. Curr Opin Struct Biol 2005; 15: 35–41
  • Mittag T, Forman-Kay JD. Atomic-level characterization of disordered protein ensembles. Curr Opin Struct Biol 2007; 17: 3–14
  • Lu Z, Klem AM, Ramu Y. Ion conduction pore is conserved among potassium channels. Nature 2001; 413: 809–813
  • Lu Z, Klem AM, Ramu Y. Coupling between voltage sensors and activation gate in voltage-gated K+ channels. J Gen Physiol 2002; 120: 663–676
  • Ferrer T, Rupp J, Piper DR, Tristani-Firouzi M. The S4-S5 linker directly couples voltage sensor movement to the activation gate in the human ether-a’-go-go-related gene (hERG) K+ channel. J Biol Chem 2006; 281: 12858–12864
  • Humphrey W, Dalke A, Schulten K. VMD: visual molecular dynamics. J Mol Graph 1996; 14: 33–38

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