Free diC14-amidine liposomes inhibit the TNF-α secretion induced by CpG sequences and lipopolysaccharides: role of lipoproteins

References

• Felgner PL, Gadek TR, Holm M, Roman R, Chan HW, Wenz M, Northrop JP, Ringold GM, Danielsen M. Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc Natl Acad Sci USA 1987; 84: 7413–7417
   PubMed Web of Science ®Google Scholar
• Zhu N, Liggitt D, Liu Y, Debs R. Systemic gene expression after intravenous DNA delivery into adult mice. Science 261:209–211.
   PubMed Web of Science ®Google Scholar
• Mahato RI, Anwer K, Tagliaferri F, Meaney C, Leonard P, Wadhwa MS, Logan M, French M, Rolland A. Biodistribution and gene expression of lipid/plasmid complexes after systemic administration. Hum Gene Ther 1998; 9: 2083–2099
   PubMed Web of Science ®Google Scholar
• Templeton NS, Lasic DD, Frederik PM, Strey HH, Roberts DD, Pavlakis GN. Improved DNA: liposome complexes for increased systemic delivery and gene expression. Nat Biotechnol 1997; 15: 647–652
   PubMed Web of Science ®Google Scholar
• McLean JW, Fox EA, Baluk P, Bolton PB, Haskell A, Pearlman R, Thurston G, Umemoto EY, McDonald DM. Organ-specific endothelial cell uptake of cationic liposome-DNA complexes in mice. Am J Physiol 1997; 273: H387–404
   PubMed Web of Science ®Google Scholar
• Dow SW, Fradkin LG, Liggitt DH, Willson AP, Heath TD, Potter TA. Lipid-DNA complexes induce potent activation of innate immune responses and antitumor activity when administered intravenously. J Immunol 1999; 163: 1552–1561
   PubMed Web of Science ®Google Scholar
• Li S, Wu SP, Whitmore M, Loeffert EJ, Wang L, Watkins SC, Pitt BR, Huang L. Effect of immune response on gene transfer to the lung via systemic administration of cationic lipidic vectors. Am J Physiol 1999; 276: L796–804
   PubMed Web of Science ®Google Scholar
• Tan Y, Li S, Pitt BR, Huang L. The inhibitory role of CpG immunostimulatory motifs in cationic lipid vector-mediated transgene expression in vivo. Hum Gene Ther 1999; 10: 2153–2161
   PubMed Web of Science ®Google Scholar
• Yew NS, Zhao H, Wu IH, Song A, Tousignant JD, Przybylska M, Cheng SH. Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs. Mol Ther 2000; 1: 255–262
   PubMed Web of Science ®Google Scholar
• Elouahabi A, Flamand V, Ozkan S, Paulart F, Vandenbranden M, Goldman M, Ruysschaert JM. Free cationic liposomes inhibit the inflammatory response to cationic lipid-DNA complex injected intravenously and enhance its transfection efficiency. Mol Ther 2003; 7: 81–88
   PubMed Web of Science ®Google Scholar
• Tousignant JD, Zhao H, Yew NS, Cheng SH, Eastman SJ, Scheule RK. DNA sequences in cationic lipid:pDNA-mediated systemic toxicities. Hum Gene Ther 2003; 14: 203–214
   PubMed Web of Science ®Google Scholar
• Mahato RI, Kawabata K, Nomura T, Takakura Y, Hashida M. Physicochemical and pharmacokinetic characteristics of plasmid DNA/cationic liposome complexes. J Pharm Sci 1995; 84: 1267–1271
   PubMed Web of Science ®Google Scholar
• Osaka G, Carey K, Cuthbertson A, Godowski P, Patapoff T, Ryan A, Gadek T, Mordenti J. Pharmacokinetics, tissue distribution, and expression efficiency of plasmid [33P]DNA following intravenous administration of DNA/cationic lipid complexes in mice: use of a novel radionuclide approach. J Pharm Sci 1996; 85: 612–618
   PubMed Web of Science ®Google Scholar
• Sakurai F, Terada T, Yasuda K, Yamashita F, Takakura Y, Hashida M. The role of tissue macrophages in the induction of proinflammatory cytokine production following intravenous injection of lipoplexes. Gene Ther 2002; 9: 1120–1126
   PubMed Web of Science ®Google Scholar
• Kwon HJ, Lee KW, Yu SH, Han JH, Kim DS. NF-kappaB-dependent regulation of tumor necrosis factor-alpha gene expression by CpG-oligodeoxynucleotides. Biochem Biophys Res Commun 2003; 311: 129–138
   PubMed Web of Science ®Google Scholar
• Ruysschaert JM, el Ouahabi A, Willeaume V, Huez G, Fuks R, Vandenbranden M, Di Stefano P. A novel cationic amphiphile for transfection of mammalian cells. Biochem Biophys Res Commun 1994; 203: 1622–1628
   PubMed Web of Science ®Google Scholar
• Chapman MJ, Goldstein S, Lagrange D, Laplaud PM. A density gradient ultracentrifugal procedure for the isolation of the major lipoprotein classes from human serum. J Lipid Res 1981; 22: 339–358
   PubMed Web of Science ®Google Scholar
• Osborne JC. Delipidation of plasma lipoproteins. Methods Enzymol 1986; 128: 213–222
   PubMed Web of Science ®Google Scholar
• Takeda K, Akira S. Toll-like receptors in innate immunity. Int Immunol 2005; 17: 1–14
   PubMed Web of Science ®Google Scholar
• Leifer CA, Kennedy MN, Mazzoni A, Lee C, Kruhlak MJ, Segal DM. TLR9 is localized in the endoplasmic reticulum prior to stimulation. J Immunol 2004; 173: 1179–1183
   PubMed Web of Science ®Google Scholar
• Tandia BM, Lonez C, Vandenbranden M, Ruysschaert JM, Elouahabi A. Lipid mixing between lipoplexes and plasma lipoproteins is a major barrier for intravenous transfection mediated by cationic lipids. J Biol Chem 2005; 280: 12255–12261
   PubMed Web of Science ®Google Scholar
• Thuahnai ST, Lund-Katz S, Williams DL, Phillips MC. Scavenger receptor class B, type I-mediated uptake of various lipids into cells. Influence of the nature of the donor particle interaction with the receptor. J Biol Chem 2001; 276: 43801–43808
   PubMed Web of Science ®Google Scholar
• Urban S, Zieseniss S, Werder M, Hauser H, Budzinski R, Engelmann B. Scavenger receptor BI transfers major lipoprotein-associated phospholipids into the cells. J Biol Chem 2000; 275: 33409–33415
   PubMed Web of Science ®Google Scholar
• de Beer MC, Castellani LW, Cai L, Stromberg AJ, de Beer FC, van der Westhuyzen DR. ApoA-II modulates the association of HDL with class B scavenger receptors SR-BI and CD36. J Lipid Res 2004; 45: 706–715
   PubMed Web of Science ®Google Scholar
• Huard K, Bourgeois P, Rhainds D, Falstrault L, Cohn JS, Brissette L. Apolipoproteins C-II and C-III inhibit selective uptake of low- and high-density lipoprotein cholesteryl esters in HepG2 cells. Int J Biochem Cell Biol 2005; 37: 1308–1318
   PubMed Web of Science ®Google Scholar
• Tandia BM, Vandenbranden M, Wattiez R, Lakhdar Z, Ruysschaert JM, Elouahabi A. Identification of human plasma proteins that bind to cationic lipid/DNA complex and analysis of their effects on transfection efficiency: implications for intravenous gene transfer. Mol Ther 2003; 8: 264–273
   PubMed Web of Science ®Google Scholar
• Lada AT, Rudel LL. Associations of low density lipoprotein particle composition with atherogenicity. Curr Opin Lipidol 2004; 15: 19–24
   PubMed Web of Science ®Google Scholar
• Scheffer PG, Teerlink T, Heine RJ. Clinical significance of the physicochemical properties of LDL in type 2 diabetes. Diabetologia 2005; 48: 808–816
   PubMed Web of Science ®Google Scholar
• Lee JY, Plakidas A, Lee WH, Heikkinen A, Chanmugam P, Bray G, Hwang DH. Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids. J Lipid Res 2003; 44: 479–486
   PubMed Web of Science ®Google Scholar
• Ares MP, Stollenwerk M, Olsson A, Kallin B, Jovinge S, Nilsson J. Decreased inducibility of TNF expression in lipid-loaded macrophages. BMC Immunol 2002; 3: 13
   PubMedGoogle Scholar
• Calder PC. Polyunsaturated fatty acids and inflammation. Biochem Soc Trans 2005; 33: 423–427
   PubMed Web of Science ®Google Scholar
• Hamilton TA, Ma GP, Chisolm GM. Oxidized low density lipoprotein suppresses the expression of tumor necrosis factor-alpha mRNA in stimulated murine peritoneal macrophages. J Immunol 1990; 144: 2343–2350
   PubMed Web of Science ®Google Scholar