Arabidopsis PEX19 is a dimeric protein that binds the peroxin PEX10

References

• Graham IA, Eastmond PJ. Pathways of straight and branched chain fatty acid catabolism in higher plants. Prog Lipid Res 2002; 41: 156–181
   PubMed Web of Science ®Google Scholar
• Reumann S. The photorespiratory pathway of leaf peroxisomes. Plant peroxisomes biochemistry, cell biology and biotechnological applications, A Baker, IA Graham. Kluwer Academic Publishers, Dordrecht 2002; 141–190
   Google Scholar
• Corpas FJ, Barroso JB, del Rio LA. Peroxisomes as a source of reactive oxygen species and nitric oxide signal molecules in plant cells. Trends Plant Sci 2001; 6: 145–150
   PubMed Web of Science ®Google Scholar
• Zolman BK, Yoder A, Bartel B. Genetic analysis of indole-3-butyric acid responses in Arabidopsis thaliana reveals four mutant classes. Genetics 2000; 156: 1323–1337
   PubMed Web of Science ®Google Scholar
• Stintzi A, Browse J. The Arabidopsis male-sterile mutant, opr3, lacks the 12-oxophytodienoic acid reductase required for jasmonate synthesis. Proc Natl Acad Sci USA 2000; 97: 10625–10630
   PubMed Web of Science ®Google Scholar
• Theodoulou FL, Job K, Slocombe SP, Footitt S, Holdsworth M, Baker A, Larson TR, Graham IA. Jasmonic acid levels are reduced in COMATOSE ATP-binding cassette transporter mutants. Implications for transport of jasmonate precursors into peroxisomes. Plant Physiol 2005; 137: 835–840
   PubMedGoogle Scholar
• Hu JP, Aguirre M, Peto C, Alonso J, Ecker J, Chory J. A role for peroxisomes in photomorphogenesis and development of Arabidopsis. Science 2002; 297: 405–409
   PubMed Web of Science ®Google Scholar
• Schumann U, Wanner G, Veenhuis M, Schmid M, Gietl C. AthPEX10, a nuclear gene essential for peroxisome and storage organelle formation during Arabidopsis embryogenesis. Proc Natl Acad Sci USA 2003; 100: 9626–9631
   PubMedGoogle Scholar
• Sparkes IA, Brandizzi F, Slocombe SP, El-Shami M, Hawes C, Baker A. An Arabidopsis pex10 null mutant is embryo lethal, implicating peroxisomes in an essential role during plant embryogenesis. Plant Physiol 2003; 133: 1809–1819
   PubMed Web of Science ®Google Scholar
• Footitt S, Slocombe SP, Larner V, Kurup S, Wu Y, Larson TR, Graham IA, Baker A, Holdsworth M. Control of germination and lipid mobilization by COMATOSE, the Arabidopsis homologue of human ALDP. Embo J 2002; 21: 2912–2922
   PubMed Web of Science ®Google Scholar
• Hettema E. H., Girzalsky W., van den Berg M., Erdmann R., Distel B. Saccharomyces cerevisiae Pex3p and Pex19p are required for proper localization and stability of peroxisomal membrane proteins. Embo J 2000; 19: 223–233
   PubMedGoogle Scholar
• South ST, Sacksteder KA, Li XL, Liu YF, Gould SJ. Inhibitors of COPI and COPII do not block PEX3-mediated peroxisome synthesis. J Cell Biol 2000; 149: 1345–1359
   PubMedGoogle Scholar
• South ST, Gould SJ. Peroxisome synthesis in the absence of preexisting peroxisomes. J Cell Biol 1999; 144: 255–266
   PubMedGoogle Scholar
• Honsho M, Hiroshige T, Fujiki Y. The membrane biogenesis peroxin Pex16p-Topogenesis and functional roles in peroxisomal membrane assembly. J Biol Chem 2002; 277: 44513–44524
   PubMedGoogle Scholar
• Gotte K, Girzalsky W, Linkert M, Baumgart E, Kammerer S, Kunau WH, Erdmann R. Pex19p, a farnesylated protein essential for peroxisome biogenesis. Mol Cell Biol 1998; 18: 616–628
   PubMed Web of Science ®Google Scholar
• Matsuzono Y, Kinoshita N, Tamura S, Shimozawa N, Hamasaki M, Ghaed K, Wanders RJA, Suzuki Y, Kondo N, Fujiki Y. Human PEX19: cDNA cloning by functional complementation, mutation analysis in a patient with Zellweger syndrome, and potential role in peroxisomal membrane assembly. Proc Natl Acad Sci USA 1999; 96: 2116–2121
   PubMed Web of Science ®Google Scholar
• Snyder WB, Faber KN, Wenzel TJ, Koller A, Luers GH, Rangell L, Keller GA, Subramani S. Pex19p interacts with Pex3p and Pex10p and is essential for peroxisome biogenesis in Pichia pastoris. Mol Biol Cell 1999; 10: 1745–1761
   PubMed Web of Science ®Google Scholar
• Soukupova M, Sprenger C, Gorgas K, Kunau WH, Dodt G. Identification and characterization of the human peroxin PEX3. Eur J Cell Biol 1999; 78: 357–374
   PubMedGoogle Scholar
• Hoepfner D, Schildknegt D, Braakman I, Philippsen P, Tabak HF. Contribution of the endoplasmic reticulum to peroxisome formation. Cell 2005; 122: 85–95
   PubMed Web of Science ®Google Scholar
• Ghaedi K, Tamura S, Okumoto K, Matsuzono Y, Fujiki Y. The peroxin Pex3p initiates membrane assembly in peroxisome biogenesis. Mol Biol Cell 2000; 11: 2085–2102
   PubMedGoogle Scholar
• Sacksteder KA, Jones JM, South ST, Li XL, Liu YF, Gould SJ. PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis. J Cell Biol 2000; 148: 931–944
   PubMed Web of Science ®Google Scholar
• Snyder WB, Koller A, Choy AJ, Subramani S. The peroxin Pex19p interacts with multiple, integral membrane proteins at the peroxisomal membrane. J Cell Biol 2000; 149: 1171–1177
   PubMed Web of Science ®Google Scholar
• Lambkin GR, Rachubinski RA. Yarrowia lipolytica cells mutant for the peroxisomal peroxin Pex19p contain structures resembling wild-type peroxisomes. Mol Biol Cell 2001; 12: 3353–3364
   PubMedGoogle Scholar
• Otzen M, Perband U, Wang D, Baerends RJS, Kunau WH, Veenhuis M, Van der Klei IJ. Hansenula polymorpha Pex19p is essential for the formation of functional peroxisomal membranes. J Biol Chem 2004; 279: 19181–19190
   PubMedGoogle Scholar
• Jones JM, Morrell JC, Gould SJ. PEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteins. J Cell Biol 2004; 164: 57–67
   PubMedGoogle Scholar
• Fransen M, Vastiau I, Brees C, Brys V, Mannaerts GP, Van Veldhoven PP. Potential role for Pex19p in assembly of PTS-receptor docking complexes. J Biol Chem 2004; 279: 12615–12624
   PubMedGoogle Scholar
• Fransen M, Wylin T, Brees C, Mannaerts GP, Van Veldhoven PP. Human Pex19p binds peroxisomal integral membrane proteins at regions distinct from their sorting sequences. Mol Cell Biol 2001; 21: 4413–4424
   PubMedGoogle Scholar
• Rottensteiner H, Kramer A, Lorenzen S, Stein K, Christiane LF, Volkmer-Engert R, Erdmann R. Peroxisomal membrane proteins contain common Pex19p-binding sites that are an integral part of their targeting signals. Mol Biol Cell 2004; 15: 3406–3417
   PubMedGoogle Scholar
• Fang Y, Morrell JC, Jones JM, Gould SJ. PEX3 functions as a PEX19 docking factor in the import of class I peroxisomal membrane proteins. J Cell Biol 2004; 164: 863–875
   PubMed Web of Science ®Google Scholar
• Fransen M, Vastiau I, Brees C, Brys V, Mannaerts GP, Van Veldhoven PP. Analysis of human Pex19p's domain structure by pentapeptide scanning mutagenesis. J Mol Biol 2005; 346: 1275–1286
   PubMedGoogle Scholar
• Shibata H, Kashiwayama Y, Imanaka T, Kato H. Domain architecture and activity of human Pex19p, a chaperone-like protein for intracellular trafficking of peroxisomal membrane proteins. J Biol Chem 2004; 279: 38486–38494
   PubMedGoogle Scholar
• Mayerhofer PU, Kattenfeld T, Roscher AA, Muntau AC. Two splice variants of human PEX19 exhibit distinct functions in peroxisomal assembly. Biochem Biophys Res Commun 2002; 291: 1180–1186
   PubMedGoogle Scholar
• Sambrook J, Russell DW. Molecular cloning, a laboratory manual. 3rd ed. New York: Cold Spring Harbour Laboratory Press; 2001.
   Google Scholar
• Tugal HB, Pool M, Baker A. Arabidopsis 22-kilodalton peroxisomal membrane protein. Nucleotide sequence analysis and biochemical characterization. Plant Physiol 1999; 120: 309–320
   PubMedGoogle Scholar
• Lisenbee CS, Heinze M, Trelease RN. Peroxisomal ascorbate peroxidase resides within a subdomain of rough endoplasmic reticulum in wild-type Arabidopsis cells. Plant Physiol 2003; 132: 870–882
   PubMedGoogle Scholar
• Lopez-Huertas E, Oh JS, Baker A. Antibodies against Pex14p block ATP-independent binding of matrix proteins to peroxisomes in vitro. FEBS Lett 1999; 459: 227–229
   PubMedGoogle Scholar
• Charlton W, Matsui K, Johnson B, Graham IA, Ohme-Takagi M, Baker A. Salt-induced expression of peroxisome-associated genes requires components of the ethylene, jasmonate and abscisic acid signalling pathways. Plant Cell Environ 2005; 28: 513–524
   Google Scholar
• Combet C, Blanchet C, Geourjon C, Deleage G. NPS@: Network Protein Sequence Analysis. Trends Biochem Sci 2000; 25: 147–150
   PubMed Web of Science ®Google Scholar
• Kamada T, Nito K, Hayashi H, Mano S, Hayashi M, Nishimura M. Functional differentiation of peroxisomes revealed by expression profiles of peroxisomal genes in Arabidopsis thaliana. Plant Cell Physiol 2003; 44: 1275–1289
   PubMedGoogle Scholar
• Zacharias DA, Violin JD, Newton AC, Tsien RY. Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells. Science 2002; 296: 913–916
   PubMed Web of Science ®Google Scholar
• Abe Y, Shodai T, Muto T, Mihara K, Torii H, Nishikawa S-i, Endo T, Kohda D. Structural basis of presequence recognition by the mitochondrial protein import receptor Tom20. Cell 2000; 100: 551–560
   PubMed Web of Science ®Google Scholar
• Brix J, Rudiger S, Bukau B, Schneider-Mergener J, Pfanner N. Distribution of binding sequences for the mitochondrial import receptors Tom20, Tom22, and Tom70 in a presequence-carrying preprotein and a non-cleavable preprotein. J Biol Chem 1999; 274: 16522–16530
   PubMedGoogle Scholar
• Notredame C, Higgins DG, Heringa J. T-coffee: A novel method for fast and accurate multiple sequence alignment. J Mol Biol 2000; 302: 205–217
   PubMed Web of Science ®Google Scholar
• Zimmermann P, Hirsch-Hoffmann M, Hennig L, Gruissem W. GENEVESTIGATOR. Arabidopsis microarray database and analysis toolbox. Plant Physiol 2004; 136: 2621–2632
   PubMed Web of Science ®Google Scholar
• Boyes DC, Zayed AM, Ascenzi R, McCaskill AJ, Hoffman NE, Davis KR, Gorlach J. Growth stage-based phenotypic analysis of Arabidopsis: A model for high throughput functional genomics in plants. Plant Cell 2001; 13: 1499–1510
   PubMed Web of Science ®Google Scholar