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Original

Quantification of the effects of a ryanodine receptor channel mutation on interaction with a ryanoid

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Pages 185-193 | Received 02 Aug 2006, Published online: 09 Jul 2009

References

  • Banerjee A. Plants and the heart. Dialog Cardiovas Med 2000; 5: 239–241
  • Williams AJ, West DJ, Sitsapesan R. Light at the end of the Ca2 + -release channel tunnel: structures and mechanisms involved in ion translocation in ryanodine receptor channels. Quart Rev Biophys 2001; 34: 61–104
  • Marban E, Wier WG. Ryanodine as a tool to determine the contributions of calcium entry and calcium release to the calcium transient and contraction of cardiac purkinje fibers. Circ Res 1985; 56: 133–138
  • Berridge MJ, Bootman MD, Roderick HL. Calcium signalling: dynamics, homeostasis and remodelling. Nat Rev Mol Cell Biol 2003; 4: 517–529
  • Rousseau E, Smith JS, Meissner G. Ryanodine modifies conductance and gating behaviour of single Ca2 +  release channel. Am J Physiol 1987; 253: C364–368
  • Ashley RH, Williams AJ. Divalent cation activation and inhibition of single calcium release channels from sheep cardiac sarcoplasmic reticulum. J Gen Physiol 1990; 95: 981–1005
  • Tinker A, Sutko JL, Ruest L, Deslongchamps P, Welch W, Airey JA, Gerzon K, Bidasee KR, Besch HR, Jr, Williams AJ. Electrophysiological effects of ryanodine derivatives on the sheep cardiac sarcoplasmic reticulum calcium-release channel. Biophys J 1996; 70: 2110–2119
  • Sutko JL, Airey JA, Welch W, Ruest L. The pharmacology of ryanodine and related compounds. Pharmacol Rev 1997; 49: 53–98
  • Williams AJ, Tanna B. The interaction of ryanoids with individual ryanodine receptor channels. Biol Res 2004; 37: 527–538
  • Welch W. Quantitative relationships between ryanoids, receptor affinity and channel conductance. Front Biosci 2002; 1: 1727–1742
  • Welch W, Williams AJ, Tinker A, Mitchell KE, Deslongchamps P, Lamothe J, Gerzon K, Bidasee KR, Besch HR, Jr, Airey JA, Sutko JL, Ruest L. Structural components of ryanodine responsible for modulation of sarcoplasmic reticulum calcium channel function. Biochem 1997; 36: 2939–2950
  • Welch W, Sutko JL, Mitchell KE, Airey JA, Ruest L. The pyrrole locus is the major orienting factor in ryanodine binding. Biochem 1996; 35: 7165–7173
  • Witcher DR, McPherson PS, Kahl SD, Lewis T, Bentley P, Mullinnix MJ, Windass JD, Campbell KP. Photoaffinity labeling of the ryanodine receptor/Ca2 +  release channel with an azido derivative of ryanodine. J Biol Chem 1994; 269: 13076–13079
  • Callaway C, Seryshev A, Wang J-P, Slavik KJ, Needleman DH, Cantu C, III, Wu Y, Jayaraman T, Marks AR, Hamilton SL. Localization of the high and low affinity [3H]Ryanodine binding sites on the skeletal muscle Ca2 +  release channel. J Biol Chem 1994; 269: 15876–15884
  • Wang R, Bolstad J, Kong H, Zhang L, Brown C, Chen SRW. The predicted TM10 transmembrane sequence of the cardiac Ca2 +  release channel (ryanodine receptor) is crucial for channel activation and gating. J Biol Chem 2004; 279: 3635–3642
  • Wang R, Zhang L, Bolstad J, Diao N, Brown C, Ruest L, Welch W, Williams AJ, Chen SRW. Residue Gln4863 within a predicted transmembrane sequence of the Ca2 +  release channel (ryanodine receptor) is critical for ryanodine interaction. J Biol Chem 2003; 278: 51557–51565
  • Ranatunga KM, Moreno-King TM, Tanna B, Wang R, Chen SRW, Ruest L, Welch W, Williams AJ. The Gln4863Ala mutation within a putative, pore-lining trans-membrane helix of the cardiac ryanodine receptor channel alters both the kinetics of ryanoid interaction and the subsequent fractional conductance. Mol Pharmacol 2005; 68: 840–846
  • Tanna B, Welch W, Ruest L, Sutko JL, Williams AJ. Voltage-sensitive equilibrium between two states within a ryanoid-modified conductance state of the ryanodine receptor channel. Biophys J 2005; 88: 2585–2596
  • Miller C. Open-state substructure of single chloride channels from Torpedo electroplax. Phil Trans Roy Soc Lon B 1982; 299: 401–411
  • Williams AJ. An introduction to the methods available for ion channel reconstitution. Microelectrode techniques: the Plymouth Workshop handbook, D Ogden. The Company of Biologists, Cambridge 1994; 79–99
  • McGarry SJ, Williams AJ. Activation of the sheep cardiac sarcoplasmic reticulum Ca2 + -release channel by analogues of sulmazole. Br J Pharmacol 1994; 111: 1212–1220
  • Tanna B, Welch W, Ruest L, Sutko JL, Williams AJ. Ryanoid modification of the cardiac muscle ryanodine receptor channel results in relocation of the tetraethylammonium binding site. J Gen Physiol 2001; 117: 385–393
  • Tanna B, Welch W, Ruest L, Sutko JL, Williams AJ. Interactions of a reversible ryanoid (21-amino-9alpha-hydroxy-ryanodine) with single cardiac ryanodine receptor channels. J Gen Physiol 1998; 112: 55–69
  • Colquhoun D, Sigworth FJ. Fitting and statistical analysis of single-channel recording. Single-channel recording, B Sakmann, E Neher. Plenum, New York & London 1983; 191–263
  • Shah PK, Sowdhamini R. Structural understanding of the transmembrane domains of inositol triphosphate receptors and ryanodine receptors towards calcium channeling. Prot Eng 2001; 14: 867–874
  • Welch W, Rheault S, West DJ, Williams AJ. A model of the putative pore region of the cardiac ryanodine receptor channel. Biophys J 2004; 87: 2335–2351
  • Saftenku E, Williams AJ, Sitsapesan R. Markovian models of low and high activity levels of cardiac ryanodine receptors. Biophys J 2001; 80: 2727–2741
  • Zahradnik I, Gyorke S, Zahradnikova A. Calcium activation of ryanodine receptor channels – reconciling RyR gating models with tetrameric channel structure. J Gen Physiol 2005; 126: 515–527
  • Hille, B. 1984. Ionic channels of excitable membranes. 1st ed. Sunderland, MA: Sinauer. pp 426.
  • Qin F, Auerbach A, Sachs F. Estimating single-channel kinetic parameters from idealized patch-clamp data containing missed events. Biophys J 1996; 70: 264–280
  • Venkataramanan L, Sigworth FJ. Applying hidden Markov models to the analysis of single ion channel activity. Biophys J 2002; 82: 1930–1942

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