Therapeutic doses of plasma rich in growth factors cannot provoke cancer by means of the IGF-1 pathway or inflammation in dogs

References

• Allin KH, Bojesen SE, Nordestgaard BG. 2009. Baseline C-reactive protein is associated with incident cancer and survival in patients with cancer. J Clin Oncol. 27:2217–2224. doi: 10.1200/JCO.2008.19.8440
   PubMed Web of Science ®Google Scholar
• Anitua E. 1999. Plasma rich in growth factors: preliminary results of use in the preparation of future sites for implants. Int J Oral Maxillofac Implants. 14:529–535.
   PubMed Web of Science ®Google Scholar
• Anitua E, Alkhraisat MH, Orive G. 2012. Perspectives and challenges in regenerative medicine using plasma rich in growth factors. J Control Release. 157:29–38. doi: 10.1016/j.jconrel.2011.07.004
   PubMed Web of Science ®Google Scholar
• Anitua E, Sánchez M, Aguirre JJ, Prado R, Padilla S, Orive G. 2014. Efficacy and safety of plasma rich in growth factors intra-articular infiltrations in the treatment of knee osteoarthritis. Arthroscopy. 30:1006–1017. doi: 10.1016/j.arthro.2014.05.021
   PubMed Web of Science ®Google Scholar
• Christensen MB, Eriksen T, Kjelgaard M. 2015. C-reactive protein: quantitative marker of surgical trauma and post-surgical complications in dogs: a systematic review. Acta Vet Scand. 57:1–10. doi: 10.1080/03461238.2015.1020856
   PubMed Web of Science ®Google Scholar
• Crossley R, Coloma A, Ríos C, Gonzalez C. 2010. Determinación de proteína C-reactiva en hembras caninas con tumores mamarios benignos y malignos. Arch Med Vet. 42:101–105. doi: 10.4067/S0301-732X2010000100014
   Web of Science ®Google Scholar
• Dabrowski R, Szczubial M, Kostro K, Wawron W, Ceron JJ, Tvarijonaviciute A. 2015. Serum insulin-like growth factor-1 and C-reactive protein concentrations before and after ovariohysterectomy in bitches with pyometra. Theriogenology. 83:474–477. doi: 10.1016/j.theriogenology.2014.09.024
   PubMed Web of Science ®Google Scholar
• Fahie MA, Ortolano GA, Guercio V, Schaffer JA, Johnston G, Au J, Hettlich BA, Phillips T, Allen MJ, Bertone AL. 2013. A randomized controlled trial of the efficacy of autologous platelet therapy for the treatment of osteoarthritis in dogs. J Am Vet Med A. 243:1291–1297. doi: 10.2460/javma.243.9.1291
   PubMed Web of Science ®Google Scholar
• Grageda E, Lozada JL, Boyne PJ, Caplanis N, McMillan PJ. 2005. Bone formation in the maxillary sinus by using platelet-rich plasma: an experimental study in sheep. J Oral Implantol. 31:2–17. doi: 10.1563/0-692.1
   PubMedGoogle Scholar
• Grahnen A, Kastrup K, Heinrich U, Gourmelen M, Preece MA, Vaccarello MA, Guevara-Aguirre J, Rosenfeld RG, Sietnieks A. 1993. Pharmacokinetics of recombinant human insulin-like growth factor I given subcutaneously to healthy volunteers and to patients with growth hormone receptor deficiency. Acta Paediatr. 82:9–13. doi: 10.1111/j.1651-2227.1993.tb12918.x
   Web of Science ®Google Scholar
• Grimberg A. 2003. Mechanisms by which IGF-I may promote cancer. Cancer Biol Ther. 2:628–633. doi: 10.4161/cbt.2.6.678
   Web of Science ®Google Scholar
• Grimberg A, Cohen P. 2000. Role of insulin-like growth factors and their binding proteins in growth control and carcinogenesis. J Cell Physiol. 183:1–9. doi: 10.1002/(SICI)1097-4652(200004)183:1<1::AID-JCP1>3.0.CO;2-J
   PubMed Web of Science ®Google Scholar
• Lim HY, Im KS, Kim NH, Kim HW, Shin JI, Yhee JY, Sur JH. 2015. Effects of obesity and obesity-related molecules on canine mammary gland tumors. Vet Pathol. 52:1045–1051. doi: 10.1177/0300985815579994
   PubMed Web of Science ®Google Scholar
• Maniscalco L, Iussich S, Morello E, Martano M, Gattino F, Miretti S, Biolatti B, Accornero P, Martignani E, Sánchez-Céspedes R, et al. 2015. Increased expression of insulin-like growth factor-1 receptor is correlated with worse survival in canine appendicular osteosarcoma. Vet J. 205:272–280. doi: 10.1016/j.tvjl.2014.09.005
   PubMed Web of Science ®Google Scholar
• Martinez-Subiela S, Cerón JJ. 2005. Analytical validation of commercial assays for the determination of haptoglobin, C-reactive protein and serum amyloid in dogs. Arch Med Vet. 37:61–66. doi: 10.4067/S0301-732X2005000100009
   Web of Science ®Google Scholar
• Otabe K, Sugimoto T, Jinbo T, Honda M, Kitao S, Hayashi S, Shimizu M, Yamamoto S. 1998. Physiological levels of C-reactive protein in normal canine sera. Vet Res Comm. 22:77–85. doi: 10.1023/A:1006071211779
   PubMed Web of Science ®Google Scholar
• Philippou A, Maridaki M, Halapas A and Koutsilieris M. 2007. The role of the insulin-like growth factor 1 (IGF-1) in skeletal muscle physiology. Vivo. 21:45–54.
   PubMed Web of Science ®Google Scholar
• Renehan AG, Zwahlen M, Minder C, O’dwye ST, Shalet SM, Egger M. 2004. Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis. Lancet. 363:1346–1353. doi: 10.1016/S0140-6736(04)16044-3
   PubMed Web of Science ®Google Scholar
• Schippinger G, Oettl K, Fankhauser F, Spirk S, Domej W, Hofmann P. 2011. Influence of intramuscular application of autologous conditioned plasma on systemic circulating IGF-1. J Sports Sci Med. 10:439–444.
   PubMed Web of Science ®Google Scholar
• Wasterlain AS, Braun HJ, Harris AHS, Kim HJ, Dragoo JL. 2013. The systemic effects of platelet-rich plasma injection. Am J Sports Med. 41:186–193. doi: 10.1177/0363546512466383
   PubMed Web of Science ®Google Scholar