Phytochemical Analysis, In vitro Assessment of Antioxidant Properties and Cytotoxic Potential of Ruta chalepensis L. Essential Oil

References

• Abdel-Razeq, H., Attiga, F. and Mansour, A. (2015). Cancer care in Jordan. Hematol./ Oncol. Stem Cell Ther. 8(2): 64-70.
   PubMedGoogle Scholar
• Al Tarawneh, M., Khatib, S. and Arqub, K. (2010). Cancer incidence in Jordan, 1996-2005. East. Mediterr. health J. 16 (8): 837-845, 2010.
   PubMedGoogle Scholar
• Khader, Y., Sharkas, G., Arkoub, K., Alfaqih, M., Nimri, O. and Khader, A. (2018). The epidemiology and trend of cancer in Jordan, 2000-2013. J. Cancer Epidemiol. 2018.
   Google Scholar
• Ferlay, J., Soerjomataram, I., Dikshit, R., Eser, S., Mathers, C., Rebelo, M., Parkin, D., Forman, D. and Bray, F. (2014). Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int. J. Cancer. 136(5): E359-E386.
   PubMed Web of Science ®Google Scholar
• Edeoga, H., Okwu, D. and Mbaebie, B. (2005). Phytochemical constituents of some Nigerian medicinal plants. Afr. J. Biotechnol. 4(7): 685-688.
   Web of Science ®Google Scholar
• Cragg, G. and Newman, D. (2000). Antineoplastic agents from natural sources: achievements and future directions. Expert Opin. Invest. Drugs. 9(12): 2783-2797.þ
   PubMed Web of Science ®Google Scholar
• Kaur, R., Kapoor, K. and Kaur, H. (2011). Plants as a source of anticancer agents. J. Nat. Prod. Plant Resour. 1(1): 119-124.þ
   Google Scholar
• Lambert, R., Skandamis, P., Coote, P. and Nychas, G. (2001). A study of the minimum inhibitory concentration and mode of action of oregano essential oil, thymol and carvacrol. J. Appl. Microbiol. 91(3): 453-462.
   PubMed Web of Science ®Google Scholar
• De Cássia da Silveira e Sá, R., Lima, T., da Nóbrega, F., de Brito, A. and de Sousa D., (2017). Analgesic-like activity of essential oil constituents: an update. Int. J. Mol. Sci. 18(12): 2392.
   Web of Science ®Google Scholar
• Koh, K., Pearce, A., Marshman, G., Finlay Jones, J. and Hart, P. (2002). Tea tree oil reduces histamine induced skin inflammation. Br. J. Dermatol. 147(6): 1212-1217.
   PubMed Web of Science ®Google Scholar
• Cha, J., Kim, Y. and Kim, J. (2010). Essential oil and 1,8-cineole from Artemisia lavandulaefolia induces apoptosis in KB cells via mitochondrial stress and caspase activation. Food Sci. Biotechnol. 19(1): 185-191.
   Web of Science ®Google Scholar
• Jayaprakasha, G., Murthy, K., Uckoo, R. and Patil, B. (2013). Chemical composition of volatile oil from Citrus limettioides and their inhibition of colon cancer cell proliferation. Ind. Crops Prod. 45: 200-207.
   Web of Science ®Google Scholar
• Carvalho, A. andrade, L., de Sousa, É. and de Sousa, D. (2015). Antitumor phenylpropanoids found in essential oils. Biomed. Res. Int. 1-21.
   Web of Science ®Google Scholar
• Nieto, G. (2017). Biological activities of three essential oils of the Lamiaceae family. Medicines. 4(3): 63.
   Google Scholar
• Oran, S. and Al-Eisawi, D. (1998). Checklist of medicinal plants in Jordan. Dirasat. 25(2): 84- 112.
   Google Scholar
• Oran, S. (2014). The status of medicinal plants in Jordan. J. Agric. Sci. Technol. A. 4(6A): 461- 467.
   Google Scholar
• Oran, S. and Al-Eisawi, D. (2015). Ethnobotanical Survey of the medicinal plants in the central mountains (North-South) in Jordan. JBES. 6(3): 381-400.
   Google Scholar
• Al-Khalil, S. (1995). A survey of plants used in Jordanian traditional medicine. Int. J. Pharmacogn. 33(4): 317-323.
   Google Scholar
• Afifi, F. and Abu-Irmaileh, B. (2000). Herbal medicine in Jordan with special emphasis on less commonly used medicinal herbs. J. Ethnopharmacol.72(1-2): 101-110.
   PubMed Web of Science ®Google Scholar
• Assaf, A., Haddadin, R., Aldouri, N., Alabbassi, R., Mashallah, S., Mohammad, M. and Bustanji, Y. (2013). Anti-cancer, anti-inflammatory and anti-microbial activities of plant extracts used against hematological tumors in the traditional medicine of Jordan. J. Ethnopharmacol. 145(3): 728-736.
   PubMed Web of Science ®Google Scholar
• Bustanji, Y., AlDouri, N., Issa, A., Mashallah, S., Assaf, A., Aburjai, T. and Mohammad, M. (2012). Cytotoxic effect of Mercurialis annua L. methanolic extract on six human solid cancer cell lines. Sci. Res. Essays. 7(37): 3218-3222.
   Google Scholar
• Abu-Rish, E., Kasabri, V., Hudaib, M., Mashalla, S., AlAlawi, L., Tawaha, K., Mohammad, M., Mohamed, Y. and Bustanji, Y. (2016). Evaluation of the antiproliferative activity of some traditional anticancer herbal remedies from Jordan. Trop. J. Pharm. Res. 15(3): 469-474.
   Web of Science ®Google Scholar
• Yousef, I., Oran, S., Bustanji, Y., Al-Eisawi, D. and Abu-Irmaileh, B. (2018). Cytotoxic effect of selected wild medicinal plant species from Jordan on Two different breast cancer cell lines, MCF 7 and T47D. Biol. Med. 10(4): 443-443C.
   Google Scholar
• Appelhans, M., Krohm, S., Manafzadeh, S. and Wen, J. (2016). Phylogenetic placement of Psilopeganum, a rare monotypic genus of Rutaceae (the citrus family) endemic to China. J. Syst. Evol. 54(5): 535-544.
   Web of Science ®Google Scholar
• Al-Said, M., Tariq, M., Al-Yahya, M. A., Rafatullah, S., Ginnawi, O. and Ageel, A. (1990). Studies on Ruta chalepensis, an ancient medicinal herb still used in traditional medicine. J. Ethnopharmacol. 28(3): 305-312.
   PubMed Web of Science ®Google Scholar
• Delazar, A., Delnavazi, M., Yassa, N., Parkhideh, S., Delazar, N., Nahar, L. and Sarker, S.D. (2012). Essential oil composition and isolation of free radical-scavenging phenolic glycosides from the aerial parts of Ajuga chamaepitys growing in Iran. Rev. Bras. Farmacogn. 22(2): 399- 305.
   Google Scholar
• Vandendool, H. and Kratz, P. (1963). A generalization of the retention index system including linear temperature programmed gas-liquid partition chromatography. J. Chromatogr. 11: 4634-71.
   Web of Science ®Google Scholar
• Wei, X., Koo, I., Kim, S. and Zhang, X. (2014). Compound identification in GC-MS by simultaneously evaluating the mass spectrum and retention index. Analyst. 139(10): 2507-2514.
   PubMed Web of Science ®Google Scholar
• Adams, R.P. (2007). Identification of essential oil components by gas chromatography/mass spectrometry: Allured publishing corporation Carol Stream, IL.
   Google Scholar
• Bouyahya, A., Dakka, N., Talbaoui, A., El Moussaoui, N., Abrini, J. and Bakri, Y. (2018). Phenolic contents and antiradical capacity of vegetable oil from Pistacia lentiscus (L). J. Mater. Environ. Sci. 9: 1518-1524.
   Google Scholar
• Polatoglu, K., Sen, A., Kandemir, A. and Gören, N. (2012). Essential oil composition and DPPH scavenging activity of endemic Tanacetum mucroniferum Hub.–Mor. & Grierson from Turkey. J. Essent. Oil-Bear. Plants. 15(1): 66-74.
   Web of Science ®Google Scholar
• Oyaýzu, M. (1986). Studies on product of browning reaction prepared from glucose amine. Jpn. J. Nutr. 44: 307-315.
   Google Scholar
• Peng, L., Wang, B. and Ren, P. (2005). Reduction of MTT by flavonoids in the absence of cells. Colloids Surf., B. 45(2): 108-111.
   PubMed Web of Science ®Google Scholar
• Soobrattee, M., Neergheen, V., Luximon-Ramma, A., Aruoma, O. and Bahorun, T. (2005). Phenolics as potential antioxidant therapeutic agents: mechanism and actions. Mutat. Res., Fundam. Mol. Mech. Mutagen. 579(1-2): 200-213.
   PubMed Web of Science ®Google Scholar
• Khorasani Esmaeili, A., Mat Taha, R., Mohajer, S. and Banisalam, B. (2015). Antioxidant activity and total phenolic and flavonoid content of various solvent extracts from in vivo and in vitro grown Trifolium pratense L. (Red Clover). Biomed. Res. Int. 2015: 1-11.
   Web of Science ®Google Scholar
• Zouari, N., Ayadi, I., Fakhfakh, N., Rebai, A. and Zouari, S. (2012). Variation of chemical composition of essential oils in wild populations of Thymus algeriensis Boiss. et Reut., a North African endemic species. Lipids Health Dis. 11(1): 28.
   PubMed Web of Science ®Google Scholar
• Baser, K., Özek, T. and Beis, S. (1996). Constituents of the essential oil of Ruta chalepensis L. from Turkey. J. Essent. Oil Res. 8(4): 413-414.
   Google Scholar
• Bagchi, G., Dwivedi, P., Singh, A., Haider, F. and Naqvi, A. (2003). Variations in essential oil constituents at different growth stages of Ruta chalepensis on cultivation at North Indian plains. J. Essent. Oil Res. 15(4): 263-264.
   Web of Science ®Google Scholar
• Haddouchi, F., Chaouche, T., Zaouali, Y., Ksouri, R., Attou, A. and Benmansour, A. (2013). Chemical composition and antimicrobial activity of the essential oils from four Ruta species growing in Algeria. Food Chem. 141(1): 253-258.
   PubMed Web of Science ®Google Scholar
• Khoury, M., Stien, D., Ouaini, N., Eparvier, V., Arnold Apostolides, N. and El Beyrouthy, M. (2014). Chemical composition and antimicrobial activity of the essential oil of Ruta chalepensis L. growing wild in Lebanon. Chem. Biodiversity. 11(12): 1990-1997.
   Google Scholar
• Lengliz, O., Mejri, J., Abderrabba, M., Khalifa, R. and Mejri, M. (2018). Ruta chalepensis L. essential oil: a new anti sprouting agent for potatoes bio conservation. J. Chem. Article ID 8547851, 6 pages.
   Google Scholar
• Tungmunnithum, D., Thongboonyou, A., Pholboon, A. and Yangsabai, A. (2018). Flavonoids and other phenolic compounds from medicinal plants for pharmaceutical and medical aspects: an overview. Medicines. 5(3): 93.
   Google Scholar
• Bendary, E., Francis, R., Ali, H., Sarwat, M. and El Hady, S. (2013). Antioxidant andstructure- activity relationships (SARs) of some phenolic and anilines compounds. Ann. Agric. Sci. 58(2): 173-181.
   Google Scholar
• Côté, J., Caillet, S., Doyon, G., Sylvain, J. and Lacroix, M. (2010). Bioactive compounds in cranberries and their biological properties. Crit. Rev. Food Sci. Nutr. 50(7): 666-679.
   PubMed Web of Science ®Google Scholar
• Babbar, N., Oberoi, H. and Sandhu, S. (2015). Therapeutic and nutraceutical potential of bioactive compounds extracted from fruit residues. Crit. Rev. Food Sci. Nutr. 55(3): 319-337.
   PubMed Web of Science ®Google Scholar
• Harborne, J. and Williams, C. (2000). Advances in flavonoid research since 1992. Phytochemistry. 55(6): 481-504.
   PubMed Web of Science ®Google Scholar
• Panche, A., Diwan, A. and Chandra, S. (2016). Flavonoids: an overview. J. Nutr. Sci. 5: e47- e47.
   PubMed Web of Science ®Google Scholar
• Ouerghemmi, I., Rebey, I., Rahali, F., Bourgou, S., Pistelli, L., Ksouri, R., Marzouk, B. and Tounsi, M. (2017). Antioxidant and antimicrobial phenolic compounds from extracts of cultivated and wild-grown Tunisian Ruta chalepensis. J. Food Drug Anal. 25(2): 350-359.
   PubMed Web of Science ®Google Scholar
• Terkmane, S., Gali, L., Bourrebaba, L., Shoji, K., Legembre, P., Konstantia, G., Ioanna, C. and Bedjou, F. (2018). Chemical composition, antioxidant and anticancer effect of Ruta chalepensis‘s extracts against human leukemic cells. Phytotherapie. 16(S1): S225-S236.
   Google Scholar
• Khlifi, D., Sghaier, R., Amouri, S., Laouini, D., Hamdi, M. and Bouajila, J. (2013). Composition and antioxidant, anti-cancer and anti-inflammatory activities of Artemisia herba- alba, Ruta chalpensis L. and Peganum harmala L. Food Chem. Toxicol. 55: 202-208.
   Web of Science ®Google Scholar
• Benazir, J., Suganthi, R., Renjini Devi, M., Suganya, K., Monisha, K., Nizar Ahamed, K. and Santhi, R. (2011). Phytochemical profiling, antimicrobial and cytotoxicity studies of methanolic extracts from Ruta graveolens. J. Pharm. Res. 4(5): 1407-1409.
   Google Scholar