85
Views
11
CrossRef citations to date
0
Altmetric
Research Article

Molecular Biology of Gastric MALT Lymphoma: Application in Clinical Management

Pages 339-344 | Published online: 04 Sep 2013

References

  • Isaacson, P.C., Muller-Hermelink, H., Pins, MA., Berger, F., Nathwani, B.N., Swerdlow, S.H. and Harris, N.L. (2001) "Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma)", In: Jaffe, E.S., Harris, N.L., Stein, H. and Vardiman, J.W., eds, WHO Classification of Tumours: Pathology and Genetics Tumours of Haematopoietic and Lymphoid Tissues, pp. 157–160.
  • Wotherspoon, AC., Doglioni, C. and Isaacson, P.G. (1992) "Low-grade gastric B-cell lymphoma of mucosa-associated lymphoid tissue (MALT): a multifocal disease", Histopatho-logy 20, 29–34.
  • Du, M.Q., Diss, T.C., Dogan, A., Ye, H.T., Aiello, A., Wotherspoon, AC., Pan, L.X. and Isaacson, P.G. (2000) "Clone-specific PCR reveals wide dissemination of gastric MALT lymphoma to the gastric mucosa", J. Pathol. 192, 488–493.
  • Thieblemont, C., Berger, F., Dumontet, C., Moullet, I., Bouafia, E, Felman, P., Salles, G. and Coiffier, B. (2000) "Mucosa-associated lymphoid tissue lymphoma is a disseminated disease in one third of 158 patients analyzed", Blood 95, 802–806.
  • Hussell, T., Isaacson, P.C., Crabtree, J.E. and Spencer, J. (1993) "The response of cells from low-grade B-cell gastric lymphomas of mucosa-associated lymphoid tissue to Helicobacter pylori", Lancet 342, 571–574.
  • Hussell, T., Isaacson, P.C., Crabtree, J.E. and Spencer, J. (1996) "Helicobacter pylori-specific tumour-infiltrating T cells provide contact dependent help for the growth of malignant B cells in low-grade gastric lymphoma of mucosa-associated lymphoid tissue", J. Pathol. 178, 122–127.
  • D'Elios, MM., Amedei, A., Manghetti, M., Costa, F., Baldari, CT., Quazi, AS., Telford, J.L., Romagnani, S. and Del Prete, G. (1999) "Impaired T-cell regulation of B-cell growth in Helicobacter pylon-related gastric low-grade MALT lymphoma", Gastroenterology 117, 1105–1112.
  • Hussell, T., Isaacson, PG., Crabtree, J.E., Dogan, A. and Spencer, J. (1993) "Immunoglobulin specificity of low grade B cell gastrointestinal lymphoma of mucosa-associated lym-phoid tissue (MALT) type", Am. J. Pathol. 142, 285–292.
  • Du, M.Q., Diss, T.C., Xu, CE, Peng, HZ., Isaacson, P.G. and Pan, LX. (1996) "Ongoing mutation in MALT lymphoma immunoglobulin VI-1 gene suggests that antigen stimulation plays a role in the clonal expansion", Leukemia 10, 1190–1197.
  • Du, M.Q., Xu, CE, Diss, T.C., Peng, HZ., Wotherspoon, AC., Isaacson, PG. and Pan, L.X. (1996) "Intestinal dissemination of gastric mucosa-associated lymphoid tissue lymphoma", Blood 88, 4445–4451.
  • Du, M.Q. and Isaacson, P.G. (2002) "Gastric MALT lymphoma: from aetiology to treatment", Lancet Oncol. 3, 97–104.
  • Auer, IA., Gascoyne, RD., Connors, J.M., Cotter, FE., Greiner, T.C., Sanger, W.G. and Horsman, D.E. (1997) "t(11;18)(q21;q21) is the most common translocation in MALT lymphomas", Ann. Oncol. 8, 979–985.
  • Ott, G., Katzenberger, T., Greiner, A., KaIla, J., Rosenwald, A., Heinrich, U., Ott, UM. and Muller Hermelink, H.K. (1997) "The t(11;18)(q21;q21) chromosome translocation is a fre-quent and specific aberration in low-grade but not high-grade malignant non-Hodgkin's lymphomas of the mucosa-associ-ated lymphoid tissue (MALT-) type", Cancer Res. 57, 3944–3948.
  • Baens, M., Maes, B., Steyls, A., Geboes, K., Marynen, P. and De Wolf-Peeters, C. (2000) "The product of the t(11;18), an API2-MLT fusion, marks nearly half of gastric MALT type lymphomas without large cell proliferation", Am. J. Pathol. 156, 1433–1439.
  • Remstein, ED., James, CD. and Kurtin, P.J. (2000) "Incidence and subtype specificity of API2-MALT1 fusion translocations in extranodal, nodal, and splenic marginal zone lymphomas", Am. J. Pathol. 156, 1183–1188.
  • Motegi, M., Yonezumi, M., Suzuki, H., Suzuki, R., Hosokawa, Y., Hosaka, S., Kodera, Y., Morishima, Y., Nakamura, S. and Seto, M. (2000) "API2-MALT1 chimeric transcripts involved in mucosa-associated lymphoid tissue type lymphoma predict heterogeneous products", Am. J. Pathol. 156, 807–812.
  • Kalla, J., Stilgenbauer, S., Schaffner, C., Wolf, S., Ott, G., Greiner, A., Rosenwald, A., Dohner, H., Muller-Hermelink, H.K. and Lichter, P. (2000) "Heterogeneity of the API2-MALT1 gene rearrangement in MALT-type lymphoma", Leukemia 14, 1967–1974.
  • Ye, H., Dogan, A., Liu, H., Wotherspoon, AC., Nicholson, A.G., Charlotte, E, Leblond, V, Speight, P.M., Isaacson, P.G. and Du, M.Q. (2002) "Markedly variable frequencies of t(11;18) in different MALT lymphoma", Blood 98(11), 767a.
  • Dierlamm, J., Baens, M., Wlodarska, I., Stefanova-Ouzounova, M., Hernandez, J.M., Hossfeld, D.K., De Wolf-Peeters, C., Hagemeijer, A., Van den Berghe, H. and Marynen, P. (1999) "The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas", Blood 93, 3601–3609.
  • Uren, G.A., O'Rourke, K., Aravind, L., Pisabarro, T.M., Seshagiri, S., Koonin, V.E. and Dixit, M.V. (2000) "Identifi-cation of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma", Mol. Cell. 6, 961–967.
  • Liu, H., Ye, H., Dogan, A., Ranaldi, R., Hamoudi, R.A., Bearzi, I., Isaacson, P.G. and Du, M.Q. (2001) "T(11;18)(q21;q21) is associated with advanced mucosa-associated lymphoid tissue lymphoma that expresses nuclear BCL10", Blood 98, 1182–1187.
  • Lucas, P.C., Yonezumi, M., Inohara, N., McAllister-Lucas, L.M., Abazeed, ME., Chen, EE, Yamaoka, S., Seto, M. and Nunez, G. (2001) "Bc110 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway", J. Biol. Chem. 276, 19012–19019.
  • Liu, H., Ye, H., Ruskone-Fourmestraux, A., de Jong, D., Pileri, S., Thiede, C., Lavergne, A., Boot, H., Caletti, G., Wundisch, T., Molina, T., Taal, B.G., Elena, S., Thomas, T., Zinzani, EL., Neubauer, A., Stolte, M., Hamoudi, R.A., Dogan, A., Isaacson, EC. and Du, M.Q. (2002) "T(11;18) is a marker for all stage gastric MALT lymphomas that will not respond to H. pylori eradication", Gastroenterology 122, 1286–1294.
  • Chuang, S.S., Lee, C., Hamoudi, R., Liu, H., Lee, ES., Ye, H., Diss, T.C., Dogan, A., Isaccson, P.G. and Du, M.Q. (2002) "High frequency of t(11;18) in gastric MALT lymphomas in Taiwan including one case with high grade transformation", Br. J. Haematol., In Press.
  • Wotherspoon, AC., Pan, LX., Diss, T.C. and Isaacson, P.G. (1992) "Cytogenetic study of B-cell lymphoma of mucosa-associated lymphoid tissue", Cancer Genet. Cytogenet. 58, 35–38.
  • Achuthan, R., Bell, S.M., Leek, J.P., Roberts, P., Horgan, K., Markham, A.F., Selby, P.J. and MacLennan, K.A. (2000) "Novel translocation of the BCL10 gene in a case of mucosa associated lymphoid tissue lymphoma", Genes Chromosomes Cancer 29, 347–349.
  • Willis, T.G., Jadayel, D.M., Du, M.Q., Peng, H., Perry, A.R., Abdul-Rauf, M., Price, H., Karran, L., Majekodunmi, O., VVlodarska, I., Pan, L., Crook, T., Hamoudi, R., Isaacson, P.G. and Dyer, M.J. (1999) "Bc110 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types", Cell 96, 35–45.
  • Zhang, Q., Siebert, R., Yan, M., Hinzmann, B., Cui, X., Xue, L., Rakestraw, K.M., Naeve, C.W., Beckmann, G., Weisenburger, D.D., Sanger, W.G., Nowotny, H., Vesely, M., Callet-Bauchu, E., Salles, G., Dixit, V.M., Rosenthal, A., Schlegelberger, B. and Morris, S.W. (1999) "Inactivating mutations and overexpres-sion of BCL10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32)", Nat. Genet. 22, 63–68.
  • Du, M.Q., Peng, H., Liu, H., Hamoudi, R.A., Diss, T.C., Willis, T.G., Ye, H., Dogan, A., Wotherspoon, AC., Dyer, M.J. and Isaacson, P.G. (2000) "BCL10 gene mutation in lymphoma", Blood 95, 3885–3890.
  • Ye, H., Dogan, A., Karran, L., Willis, T.G., Chen, L., VVlodarska, I., Dyer, M.J., Isaacson, P.G. and Du, M.Q. (2000) "BCL10 expression in normal and neoplastic lymphoid tissue: nuclear localization in MALT lymphoma", Am. J. Pathol. 157, 1147–1154.
  • Maes, B., Demunter, A., Peeters, B. and Wolf-Peeters, C. (2002) "BCL10 mutation does not represent an important pathogenic mechanism in gastric MALT-type lymphoma, and the presence of the API2-MLT fusion is associated with aberrant nuclear BCL10 expression", Blood 99, 1398–1404.
  • Yoneda, T., Imaizumi, K., Maeda, M., Yui, D., Manabe, T., Katayama, T., Sato, N., Gomi, F., Morihara, T., Mori, Y., Miyoshi, K., Hitomi, J., Ugawa, S., Yamada, S., Okabe, M. and Tohyama, M. (2000) "Regulatory mechanisms of TRAF2-mediated signal transduction by Bc110, a MALT lymphoma-associated protein", J. Biol. Chem. 275, 11114–11120.
  • Morris, S.W. (2001) "Oncogene deregulation in B-cell non-Hodgkin's lymphoma: recent advances", American Society of Hematology Education Program Book, pp. 191–204.
  • Ruland, J., Duncan, CS., Elia, A., del Barco, B., Nguyen, L., Plyte, S., Millar, D.C., Bouchard, D., Wakeham, A., Ohashi, P.S. and Mak, T.W. (2001) "Bc110 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure", 104, 33–42.
  • Wotherspoon, AC., Doglioni, C., Diss, T.C., Pan, L., Moschini, A., de Boni, M. and Isaacson, P.G. (1993) "Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helico-bacter pylori", Lancet 342, 575–577.
  • Isaacson, P.C., Diss, T.C., Wotherspoon, A.C., Barbazza, R., de Boni, M. and Doglioni, C. (1999) "Long-term follow-up of gastric MALT lymphoma treated by eradication of H. pylori with antibodies", Gastroenterology 117, 750–751.
  • Begum, S., Sano, T., Endo, H., Kawamata, H. and Urakami, Y. (2000) "Mucosal change of the stomach with low-grade mucosa-associated lymphoid tissue lymphoma after eradica-tion of Helicobacter pylori: follow-up study of 48 cases", J. Med. Investig. 47, 36–46.
  • Savio, A., Zamboni, G., Capelli, R, Negrini, R., Santandrea, G., Scarpa, A., Fuini, A., Pasini, F., Ambrosetti, A., Paterlini, A., Buffoli F., Angelini, CE, Cesari, R, Rolfi, F., Graffeo, M., Pascarella, A., Valli, M., Mombello, A., Ederle, A. and Franzin, G. (2000) "Relapse of low-grade gastric MALT lymphoma after Helicobacter pylori eradication: true relapse or persistence? Long-term post-treatment follow-up of a multi-center trial in the north-east of Italy and evaluation of the diagnostic protocol's adequacy", Recent Results Cancer Res. 156, 116–124.
  • Bayerdorffer, E., Neubauer, A., Rudolph, B., Thiede, C., Lehn, N., Eidt, S. and Stolte, M. (1995) "Regression of primary gastric lymphoma of mucosa-associated lymphoid tissue type after cure of Helicobacter pylori infection. MALT Lymphoma Study Group", Lancet 345, 1591–1594.
  • Roggero, E., Zucca, E., Pinotti, G., Pascarella, A., Capella, C., Savio, A., Pedrinis, E., Paterlini, A., Venco, A. and Cavalli, E (1995) "Eradication of Helicobacter pylori infection in primary low-grade gastric lymphoma of mucosa-associated lymphoid tissue", Ann. Intern. Med. 122, 767–769.
  • Sackmann, M., Morgner, A., Rudolph, B., Neubauer, A., Thiede, C., Schulz, H., Kraemer, W., Boersch, G., Rohde, R, Seifert, E., Stolte, M. and Bayerdoerffer, E. (1997) "Regression of gastric MALT lymphoma after eradication of Helicobacter pylori is predicted by endosonographic staging. MALT Lymphoma Study Group", Gastroenterology 113, 1087–1090.
  • Montalban, C., Manzanal, A., Boixeda, D., Redondo, C., Alvarez, I., Calleja, J.L. and Bellas, C. (1997) "Helicobacter pylori eradication for the treatment of low-grade gastric MALT lymphoma: follow-up together with sequential molecular studies", Ann. Oncol. 8\(Suppl. 2), 37–39.
  • Steinbach, G., Ford, R., Glober, G., Sample, D., Hagemeister, F.B., Lynch, P.M., McLaughlin, P.W., Rodriguez, M.A., Romaguera, J.E., Sarris, A.H., Younes, A., Luthra, R., Manning, J.T., Johnson, CM., Lahoti, S., Shen, Y., Lee, J.E., Winn, R.J., Genta, R.M., Graham, D.Y. and Cabanillas, EE (1999) "Antibiotic treatment of gastric lymphoma of mucosa-associated lymphoid tissue. An uncontrolled trial", Ann. Intern. Med. 131, 88–95.
  • Thiede, C., Wundisch, T., Neubauer, B., Alpen, B., Morgner, A., Ritter, M., Ehninger, G., Stolte, M., Bayerdorffer, E. and Neubauer, A. (2000) "Eradication of Helicobacter pylori and stability of remissions in low-grade gastric B-cell lymphomas of the mucosa-associated lymphoid tissue: results of an ongoing multicenter trial", Recent Results Cancer Res. 156, 125–133.
  • Ruskone-Fourmestraux, A., Lavergne, A., Aegerter, Megraud, E, Palazzo, L., de Mascarel, A., Molina, T. and Rambaud, J.L. (2001) "Predictive factors for regression of gastric MALT lymphoma after anti-Helicobacter pylori treat-ment", Gut 48, 297–303.
  • Nakamura, S., Matsumoto, T., Suekane, H., Takeshita, M., Hizawa, K., Kawasaki, M., Yao, T., Tsuneyoshi, M., Iida, M. and Fujishima, M. (2001) "Predictive value of endoscopic ultrasonography for regression of gastric low grade and high grade MALT lymphomas after eradication of Helicobacter pylori", Gut 48, 454–460.
  • Morgner, A., Miehlke, S., Fischbach, W., Schmitt, W., Muller-Hermelink, H., Greiner, A., Thiede, C., Schetelig, J., Neubauer, A., Stolte, M., Ehninger, G. and Bayerdorffer, E. (2001) "Complete remission of primary high-grade B-cell gastric lymphoma after cure of Helicobacter pylori infection", J. Clin. Oncol. 19, 2041–2048.
  • Liu, H., Ruskone Fourmestraux, A., Lavergne-Slove, A., Ye, H., Molina, T., Bouhnik, Y., Hamoudi, R.A., Diss, T.C., Dogan, A., Megraud, E, Rambaud, J.C., Du, M.Q. and Isaacson, P.G. (2000) "Resistance of t(11;18) positive gastric mucosa-associated lymphoid tissue lymphoma to Helicobacter pylori eradication therapy", Lancet 357, 39–40.
  • Alpen, B., Neubauer, A., Dierlamm, J., Marynen, R, Thiede, C., Bayerdorfer, E. and Stolte, M. (2000) "Translocation t(11;18) absent in early gastric marginal zone B-cell lymphoma of MALT type responding to eradication of Helicobacter pylori infection", Blood 95, 4014–4015.
  • Nakamura, T., Nakamura, S., Yonezumi, M., Suzuki, T., Matsuura, A., Yatabe, Y, Yokoi, T., Ohashi, K. and Seto, M. (2000) "Helicobacter pylori and the t(11;18)(q21;q21) transloca-tion in gastric low-grade B-cell lymphoma of mucosa-associated lymphoid tissue type", Jpn. J. Cancer Res. 91, 301–309.
  • Raderer, M., Ostereicher, C., Machold, K., Formanek, M., ebiger, W., nz, M., agosics, B. and Chott, A. (2001) "Impaired response of gastric MALT-lymphoma to Helicobacter pylori eradication in patients with autoimmune disease", Ann. Oncol. 12, 937–939.
  • Gronbaek, K., Straten, RT., Ralfkiaer, E., Ahrenkiel, V, Andersen, M.K., Hansen, N.E., Zeuthen, J., Hou-Jensen, K. and Guldberg, P. (1998) "Somatic Fas mutations in non-Hodgkin's lymphoma: association with extranodal disease and autoimmunity", Blood 92, 3018–3024.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.