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Hematology Volume 8, 2003 - Issue 1
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Research Article

Detection of Erythrocytes Deficient of Glycosylphosphatidyl-inositol Anchored Membrane Proteins in Patients with Paroxysmal Nocturnal Hemoglobinuria by the Toxin HEC Secreted by Aeromonas hydrophila J-1

Jian WangNational Laboratory of Medical Molecular BiologyInstitute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing100005, People's Republic of China
,
Hai-li LiuNational Laboratory of Medical Molecular BiologyInstitute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing100005, People's Republic of China
,
Cai-min XuNational Laboratory of Medical Molecular BiologyInstitute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing100005, People's Republic of China
,
Yang YangNational Laboratory of Medical Molecular BiologyInstitute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing100005, People's Republic of China
,
Zhao-jiang LvPeking Union Medical College HospitalBeijing100730, People's Republic of China
,
Hua-zhen PangNational Laboratory of Medical Molecular BiologyInstitute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing100005, People's Republic of China
&
Zhi-nan ZhangPeking Union Medical College HospitalBeijing100730, People's Republic of China
 show all
Pages 41-46 | Published online: 04 Sep 2013

References

  • Ham, T.H. (1937) "Chronic hemolytic anemia with paroxysmal nocturnal hemoglobinuria: study of the mechanism of hemolytic in relation to acid base equilibrium", N. Engl. J. Med. 217, 915–918.
  • Zhang, Z., Pan, H. and Feng, L. (1984) "Diagnostic value of cobra venom factor hemolysis test", Chin. J. Hematol. 5, 41–44.
  • Lv, Z-J., Du, T. and Zhang, Z. (1997) "The clinical implication of detection of CD59- cells in paroxysmal nocturnal hemoglobi-nuria", Chin. J. Hematol. 18, 513–516.
  • Diep, D.B. and Nelson, K.L. (1998) "Glycosylphosphatidyli-nositol anchors of membrane glycoproteins are binding determinants for the channel-forming toxin aerolysin", J. Biol. Chem. 273, 2355–2360.
  • Brodsky, R.A., Mukhina, G.L., Nelson, K.L., Lawrence, T.S., Jones, R.J. and Buckley, J.T. (1999) "Resistance of paro-xysmal nocturnal hemoglobinuria cells to the glycosylpho-sphatidylinositol-binding toxin aerolysin", Blood 93(5), 1749–1756.
  • Tu, X. and Lu, C. (1992) "Purification and characterization of HEC toxin produced by Aeromonas hydrophila", Acta Microbiol. Sin. 32(6), 432–438.
  • Laemli, U.K. (1970) "Cleavage of structural protein during the assembly of the head of bactriophage T4", Nature 227, 680–685.

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