Mutations in the p53 Gene in Acute Myeloid Leukemia Patients Correlate with Poor Prognosis

References

• Diamandis, E.P. (1995) “Clinical applications of the p53 tumor suppressor gene”. Clinica Chimica Acta 237, 79–90.
   PubMed Web of Science ®Google Scholar
• Lee, J.M. and Bernstein, A. (1995) “Apoptosis, cancer and the p53 tumour suppressor gene”, Cancer and Methastasis Reviews 14, 149–161.
   PubMed Web of Science ®Google Scholar
• Fung, C.Y. and Fisher, D.E. (1995) “p53: from molecular mechanisms to prognosis in cancer”, Journal of Clinical Oncology 13, 808–811.
   PubMed Web of Science ®Google Scholar
• Lane, D.P. and Crawford, L.V. (1979) “Tantigen is bound to a host protein in SV40-transformed cells”, Nature 278, 261.
   PubMed Web of Science ®Google Scholar
• Prokocimer, M. and Rotter, V. (1994) “Structure and function of p53 in normal cells and their aberrations in cancer cells: projection on the hematologic cell lineages”, Blood 84, 2391–2411.
   PubMed Web of Science ®Google Scholar
• Kuerbitz, S.J., Plunkett, B.S., Walsh, W.V. and Kastan, M.B. (1992) “Wild-type p53 is a cell cycle checkpoint determinant following irradiation”, Proceedings of the National Academy of Sciences of the USA 89, 7491–7495.
   PubMed Web of Science ®Google Scholar
• Kastan, M.B., Onyekwere, O., Sidransky, D., Vogelstein, B. and Craig, R.W. (1991) “Participation of p53 protein in the cellular response to DNA damage”, Cancer Research 51, 6304–6311.
   PubMed Web of Science ®Google Scholar
• Hollstein, M., Sidransky, D., Vogelstein, B. and Harris, C.C. (1991) “p53 mutations in human cancers”, Science 253, 49–53.
   PubMed Web of Science ®Google Scholar
• Bosari, S. and Viale, G. (1995) “The clinical significance of p53 aberrations in human tumours”, Virchows Archives 427, 229–241.
   PubMed Web of Science ®Google Scholar
• Velculescu, V.E. and El-Deiry, W.S. (1996) “Biological and clinical importance of the p53 tumor suppressor gene”, Clinical Chemistry 42, 858–868.
   PubMed Web of Science ®Google Scholar
• Imamura, J., Miyoshi, I. and Koeffler, P. (1994) “p53 in hematologic malignancies”, Blood 84, 2412–2421.
   PubMed Web of Science ®Google Scholar
• Guinn, B. and Padua, R.A. (1997) “Do p53 mutations have a role in the initiation and progression of leukemia?”, Cancer Journal 8, 1–9.
   Web of Science ®Google Scholar
• Fenaux, P., Preudhomme, C., Quiquandon, I., Jonveaux, P., Laï, J.L., Vanrumbeke, M., Loucheux-Lefebvre, M.H., Bauters, F., Berger, R. and Kerckaert, J.P. (1992) “Mutations of the p53 gene in acute myeloid leukemia”, British Journal of Haematology 80, 178–183.
   PubMed Web of Science ®Google Scholar
• Hu, G., Zhang, W. and Deisseroth, A.B. (1992) “p53 gene mutations in acute myelogenous leukaemia”, British Journal of Haematology 81, 489–494.
   PubMed Web of Science ®Google Scholar
• Kurosawa, M., Okabe, M., Kunieda, Y. and Asaka, M. (1995) “Analysis of the p53 gene mutations in acute myelogenous leukemia: the p53 gene mutations associated with a deletion of chromosome 17”, Annals of Hematology 71, 83–87.
   PubMed Web of Science ®Google Scholar
• Wattel, E., Preudhomme, C., Hecquet, B., Vanrumbeke, M., Quesnel, B., Dervite, I., Morel, P. and Fenaux, P. (1994) “p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies”, Blood 84, 3148–3157.
   PubMed Web of Science ®Google Scholar
• Nakano, Y., Kiyoi, H., Miyawaki, S., Asou, N., Ohno, R., Saito, H. and Naoe, T. (1999), British Journal of Haematology 104, 659–664.
   PubMed Web of Science ®Google Scholar
• Nakano, Y., Naoe, T., Kiyoi, H., Kitamura, K., Minami, S., Miyawaki, S., Asou, N., Kuriyama, K., Kusumoto, S., Shimazaki, C., Akiyama, H., Saito, K., Nishimura, M., Motoji, T., Shinagawa, K., Saito, H. and Ohno, R. (2000) “Prognostic value of p53 gene mutations and the product expression in de novo acute myeloid leukemia”, European Journal of Haematology 65, 23–31.
   PubMed Web of Science ®Google Scholar
• Seliger, B., Papadileris, S., Vogel, D., Hess, D., Brendel, C, Storkel, S., Ortel, J., Kolbe, K., Huber, C., Huhn, D. and Neubauer, A. (1996) “Analysis of the p53 and MDM-2 gene in acute myeloid leukemia”, European Journal of Haematology 57, 230–240.
   PubMed Web of Science ®Google Scholar
• Lorand, I.G.H., Souza, C.A. and Costa, F.F. (1984) “Hematological toxicity associated with agricultural chemicals”, Lancet 1, 404.
   PubMed Web of Science ®Google Scholar
• Bennett, J.M., Catovsky, D., Daniel, M.-T., Flandrin, G., Galton, D.A.G., Gralnick, H.R. and Sultan, C. (1976) “Proposals for classification of the acute leukaemias: French-American-British (FAB) Cooperative Group”, British Journal of Haematology 33, 451–458.
   PubMed Web of Science ®Google Scholar
• Bennett, J.M., Catovsky, D., Daniel, M.-T., Flandrin, G., Galton, D.A.G., Gralnick, H.R. and Sultan, C. (1985) “Criteria for the diagnosis of acute leukemia of megakaryocyte lineage (M7): a report of the French-American-British Cooperative Group”, Annals of Internal Medicine 103, 460–462.
   PubMed Web of Science ®Google Scholar
• Bennett, J.M., Catovsky, D., Daniel, M.-T., Flandrin, G., Galton, D.A.G., Gralnick, H.R. and Sultan, C. (1985) “Proposed revised criteria for the classification of acute myeloid leukemia: a report of the French-American-British Cooperative Group”, Annals of Internal Medicine 103, 626–629.
   PubMed Web of Science ®Google Scholar
• Yunis, J.J. (1981) “New chromosome techniques in the study of human neoplasia”, Human Pathology 12, 540–549.
   PubMed Web of Science ®Google Scholar
• Testa, J.R. and Rowley, J.D. (1980) “Chromosomes in leukemia and lymphoma with special emphasis on methodology”, In: Catovsky, D., ed, The Leukemia Cell (Churchill-Livingstone, Edinburg), p 184.
   Google Scholar
• Mitelman, F. (1991) In: ISNC: Guidelines for Cancer Cytogenetics, Supplement to an International System for Human Cytogenetic Nomenclature (Karger, Basel).
   Google Scholar
• Büchner, T., Hiddemann, W. Loffler, G., Gassmann, W., Maschmeyer, G., Heit, W., Hossfeld, D., Weh, H., Ludwig, W.-D., Thiel, E., Nowrousian, M., Aul, C., Lengfelder, E., Lathan, B., Mainzer, K., Urbanitz, D., Emmerich, B., Middelhoff, G., Donhuijsen-Ant, H.R., Hellriegel, H.-P. and Heinecke, A. (1991) “Improved cure rate by very early intensification combined with prolonged maintenance chemotherapy in patients with acute myeloid leukemia: data from the AML Cooperative Group”, Seminars in Hematology 28 (3, Suppl. 4), 76–79.
   PubMed Web of Science ®Google Scholar
• Wahlin, A., Hörnsten, P. and Jonsson, H. (1991) “Remission rate and survival in acute myeloid leukemia: impact of selection and chemotherapy”, European Journal of Haematology 46, 240–247.
   PubMed Web of Science ®Google Scholar
• Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning, a Laboratory Manual, 2nd ed. (Cold Spring Harbor Laboratory, Cold Spring Harbor, NY).
   Google Scholar
• Saiki, R.K., Gelfand, D.H., Stoffel, S., Scharf, S.J., Higushi, R., Horn, G.T., Mullis, K.B. and Erlich, H.A. (1988) “Primer-directed enzymatic amplification of DNA with thermostable DNA polymerase”, Science 239, 487–491.
   PubMed Web of Science ®Google Scholar
• Orita, M., Iwahana, H., Kanazawa, H., Hayashi, K. and Sekiya, T. (1989) “Detection of polymorphisms of human DNA by gel electrophoresis as single-strand coformation- polymorphisms”, Proceedings of the National Academy of Sciences of the USA 86, 2766–2770.
   PubMed Web of Science ®Google Scholar
• Mohabeer, A.J., Hiti, A.L. and Martin, W.J. (1991) “Nonradioactive single strand conformation polymorphism (SSCP) using the Pharmacia “PhastSystem””, Nucleic Acids Research 19, 3154.
   PubMed Web of Science ®Google Scholar
• Conover, W.J. (1971) Practical Nonparametric Statistics (Wiley, New York).
   Google Scholar
• Collett, D. (1994) Modelling Survival Data in Medical Research (Chapman & Hall, Londres).
   Google Scholar
• Trecca, D., Longo, L., Biondi, A., Cro, L., Calori, R., Grignani, F., Maiolo, A.T., Pelicci, P.G. and Neri, A. (1994) “Analysis of p53 gene mutations in acute myeloid leukemia”, American Journal of Hematology 46, 304–309.
   PubMed Web of Science ®Google Scholar
• Bühler-Leclerc, M., Gratwohl, A. and Senn, H. (1993) “Occurrence of point mutations in p53 gene is not increased in patients with acute myeloid leukaemia carrying an activating N-ras mutation”, British Journal of Haematology 84, 443–450.
   PubMed Web of Science ®Google Scholar
• Dicciani, M.B., Yu, J., Hsiao, M., Mukherjee, S., Shao, L.-E. and Yu, A.L. (1994) “Clinical significance of p53 mutations in relapsed T-cell acute lymphoblastic leukemia”, Blood 84, 3105–3112.
   PubMed Web of Science ®Google Scholar
• Preudhomme, C., Dervite, I., Wattel, E., Vanrumbeke, M., Flactif, M., Lai, J.C., Hecquet, B., Coppin, M.C., Nelken, B., Gosselin, B. and Fenaux, P. (1995) “Clinical significance of p53 mutations in newly diagnosed Burkitt's lymphoma and acute lymphoblastic leukemia: a report of 48 cases”, Journal of Clinical Oncology 13, 812–820.
   PubMed Web of Science ®Google Scholar
• Liang, Y.-Y., Esteve, A., Martel-Planche, G., Takahashi, S., Lu, S.-H., Montesano, R. and Holistein, M. (1995) “p53 mutations in esophageal tumors from high-incidence areas of China”, International Journal of Cancer 61, 611–614.
   PubMed Web of Science ®Google Scholar
• Bhatia, K., Gutiérrez, M.I., Huppi, K. and Magrath, I.T. (1992) “PCR detection of a neutral CGA/CGG dimorphism in exon 6 of the human p53 gene”, Nucleic Acids Research 20, 928.
   PubMed Web of Science ®Google Scholar
• Chang, Y.-S., Lin, Y.-J., Tsai, C.-N., Shu, C.-H., Tsai, M.-S., Choo, K.-B. and Liu, S.-T. (1992) “Detection of mutations in the p53 gene in human head and neck carcinomas by single strand conformation polymorphism analysis”, Cancer Letters 67, 167–174.
   PubMed Web of Science ®Google Scholar
• Fenaux, P., Jonveaux, P., Quiquandon, I., Lai, J.L., Pignon, J.M., Loucheaux-Lefebvre, M.H., Bauters, F., Berger, R. and Kerckaert, J.P. (1991) “p53 gene mutations in acute myeloid leukemia with 17p monosomy”. Blood 78, 1652–1657.
   PubMed Web of Science ®Google Scholar
• Nakai, H., Misawa, S., Tanaka, S., Nishigaki, H., Taniwaki, M., Yokota, S., Horiike, S., Takashima, T., Seriu, T., Nakagawa, H., Fujii, H., Shimazaki, C., Okada, H., Toguchida, J., Ishizaki, K., Abe, T. and Kashima, K. (1993) “p53 gene mutations and loss of a chromosome 17p in Philadelphia chromosome (Ph1)-positive acute leukemia”, Leukemia 7, 1547–1551.
   PubMed Web of Science ®Google Scholar
• Misawa, S., Horiike, S., Kaneko, H., Sasai, Y., Ueda, Y., Nakao, M., Yokota, S., Taniwaki, M., Fujii, H., Nakagawa, H., Tsuda, S. and Kashima, K. (1998) “Significance of chromosomal alterations and mutations of the N-ras and TP53 genes in relation to leukemogenesis of acute myeloid leukemia”. Leukemia Research 22, 631–637.
   PubMed Web of Science ®Google Scholar
• Buchman, V.J., Chumakov, P.M., Ninkina, N.N., Samarina, O.P. and Georgiev, G.P. (1988) “A variation in the structure of the protein-coding region of the human p53 gene”, Gene 70, 245–252.
   PubMed Web of Science ®Google Scholar
• Pignon, J.M., Vinatier, I., Fanen, P., Jonveaux, P., Tournilhac, O., Imbert, M., Rochant, H. and Goossens, M. (1994) “Exhaustive analysis of the p53 gene coding sequence by denaturing gradient gel electrophoresis: application to the detection of point mutations in acute leukemias”, Human Mutation 3, 126–132.
   PubMed Web of Science ®Google Scholar
• Hussain, S.P. and Harris, C. (1999) “p53 mutation spectrum and load: the generation of hypotheses linking the exposure of endogenous or exogenous carcinogens to human cancer”, Mutation Research 428, 23–32.
   PubMed Web of Science ®Google Scholar
• Kocialkowski, S., Pezzella, F., Morrison, H., Jones, M., Laha, S., Harris, A.L., Mason, D.Y. and Gatter, K.C. (1995) “Mutations in the p53 gene are not limited to classic hot spots and are not predictive of p53 protein expression in high-grade non- Hodgkin's lymphoma”, British Journal of Haematology 89, 55–60.
   PubMed Web of Science ®Google Scholar
• Nishida, N., Fukuda, Y., Kokuryu, H., Toguchida, J., Yandell, D.W., Ikenega, M., Imura, H. and Ishizaki, K. (1993) “Role and mutational heterogeneity of the p53 gene in hepatocellular carcinoma”, Cancer Research 53, 368–372.
   PubMed Web of Science ®Google Scholar
• Chi, S.-G., White, W.V., Meyers, F.J., Siders, D.B., Lee, F. and Gumerlock, P.H. (1994) “p53 in prostate cancer: frequent expressed transition mutations”. Journal of the National Cancer Institute 86, 926–933.
   PubMed Web of Science ®Google Scholar
• Tanaka, H., Shibagaki, I., Shimada, Y., Wagata, T., Imamura, M. and Ishizaki, K. (1996) “Characterization of p53 gene mutations in esophageal squamous cell carcinoma cell lines: increased frequency and different spectrum of mutations from primary tumors”. International Journal of Cancer 65, 372–376.
   PubMed Web of Science ®Google Scholar
• Lane, D.P. (1994) “p53 and human cancers”, British Medical Bulletin 50, 582–599.
   PubMed Web of Science ®Google Scholar
• Casey, G., Lopez, M.E., Ramos, J.C., Plummer, S.J., Arboleda, M.J., Shaughnessy, M., Karlan, B. and Slamon, D.J. (1996) “DNA sequence analysis of exons 2 through 11 and immunohistochemical staining are required to detect all known p53 alterations in human malignancies”, Oncogene 13, 1971–1981.
   PubMed Web of Science ®Google Scholar
• Ciesielski, D., Dziewulska-Bokiniek, A., Zoltoeska, A., Roszkiewicz, A., Kopacz, A. and Wojtacki, J. (1995) “p53 expression in breast cancer related to prognostic factors”, Neoplasma 42, 235–237.
   PubMed Web of Science ®Google Scholar
• Field, J.K., Spandidos, D.A., Malliri, A., Gosney, J.R., Yiagnisis, M. and Stell, P.M. (1991) “Elevated p53 expression correlates with a history of heavy smoking in squamous cell carcinoma of the head and neck”, British Journal of Cancer 64, 573–577.
   PubMed Web of Science ®Google Scholar
• Ohue, M., Tomita, N., Monden, T., Fujita, M., Fukunaga, M., Takami, K., Yana, I., Ohnishi, T., Enomoto, T., Inoue, M., Shimano, T. and Mori, T. (1994) “A frequent alteration of the p53 gene in carcinoma in adenoma of colon”, Cancer Research 54, 4798–4804.
   PubMed Web of Science ®Google Scholar
• Kusser, W.C., Miao, X., Glickman, B.W., Friedland, J., Rothman, N., Hemstreet, G.P., Mellot, J., Swan, D.C., Schulte, P.A. and Hayes, R.B. (1994)” p53 mutations in human bladder cancer“, Environmental and Molecular Mutation 24, 156–160.
   PubMed Web of Science ®Google Scholar