Chronic Lymphocytic Leukaemia—the Haematologic Basis for Diagnosis and Treatment

References

• Foa, R. and Hoffbrand, A.V. (2000) “Editorial: Biology of chronic lymphocytic leukemia”, Rev. Clin. Exp. Hematoi. 4, 3–4.
   Google Scholar
• Rozman, C. and Montserrat, E. (1995) “Chronic lymphocytic leukemia”, N. Engl. J. Med. 333, 1052–1057.
   PubMed Web of Science ®Google Scholar
• Foon, K.A. (1995) “Chronic lymphoid leukemias: recent advances in biology and therapy”. Stem Cells 13, 1–21.
   PubMed Web of Science ®Google Scholar
• de Lima, M., O'Brien, S., Lerner, S. and Keating, M.J. (1998) “Chronic lymphocytic leukemia in the young patient”, Semin. Oncol 25, 107–116.
   PubMed Web of Science ®Google Scholar
• La Civita, L., Zignego, A.L., Monti, M., Longombardo, G., Greco, F., Pasero, G. and Ferri, C. (1996) “Type C hepatitis and chronic lymphocytic leukaemia”, Eur. J. Cancer 32A, 1819–1820.
   PubMed Web of Science ®Google Scholar
• Hamblin, T.J. and Oscier, D.G. (1998) “Chronic lymphocytic leukaemia”, In: Whittaker, J.A. and Holmes, J., eds, Leukaemia and Associated Diseases (Blackwell Science, Oxford), pp 105–135.
   Google Scholar
• Kantor, A.B. (1991) “The development and repertoire of B-l cells (CD5 B cells)”, Immunol. Today 12, 389–391.
   PubMedGoogle Scholar
• Caligaris-Cappio, F. (2000) “Biology of chronic lymphocytic leukemia”, Rev. Clin. Exp. Hematoi. 4, 5–21.
   PubMedGoogle Scholar
• Matutes, E., Owusu-Ankomah, K., Morilla, R., Garcia Marco, J., Houlihan, A., Que, T.H. and Catovsky, D. (1994) “The immunological profile of B-cell disorders and proposal of a scoring system for the diagnosis of CLL”, Leukemia 8, 1640–1645.
   PubMed Web of Science ®Google Scholar
• Matutes, E. (1996) “Trisomy 12 in chronic lymphocytic leukaemia”, Leuk. Res. 20, 375–377.
   PubMed Web of Science ®Google Scholar
• Dascalescu, C., Gressin, R., Callanan, M., Sotto, J.J. and Leroux, D. (1996) “t(11; 14)(q13; q32): Chronic lymphocytic leukaemia or mantle cell leukaemia?”, Br. J. Haematol. 95, 572–573.
   PubMed Web of Science ®Google Scholar
• Cuneo, A., De Angeli, C., Roberti, M.G., Piva, N., Bigoni, R., Gandini, D., et al., (1996) “Richter's syndrome in a case of atypical chronic lymphocytic leukaemia with the t(11; 14)(q13; q32): role for a p63 exon 7 gene mutation”, Br. J. Haematol. 92, 375–381.
   PubMed Web of Science ®Google Scholar
• Rai, K.R., Sawitsky, A., Cronkite, E.P., Chanana, A.D., Levy, R.N. and Pasternack, B.S. (1975) “Clinical staging of chronic lymphocytic leukemia”, Blood 46, 219–234.
   PubMed Web of Science ®Google Scholar
• Binet, J.L., Catovsky, D., Chandra, P., Dighiero, G., Montserrat, E., Rai, K.R. and Sawitsky, A. (1981) “Chronic lymphocytic leukaemia: proposals for a revised prognostic staging system”, Br. J. Haematol. 48, 365–367.
   PubMed Web of Science ®Google Scholar
• Matutes, E. and Polliack, A. (2000) “Morphological and immunophenotypic features of chronic lymphocytic leukemia”, Rev. Clin. Exp. Hematoi. 4, 22–47.
   PubMedGoogle Scholar
• Geisler, C.H., Hou-Jensen, K., Myhre Jensen, O., Tinggaard-Pedersen, N., Mark Hansen, M., Hansen, N.E., et al., (1996) “The bone-marrow infiltration pattern in B-cell chronic lymphocytic leukemia is not an important prognostic factor”, Eur. J. Haematol. 57, 292–300.
   PubMed Web of Science ®Google Scholar
• Damle, R.N., Wasil, T., Fais, F., Ghiotto, F., Valetta, A., Allen, S.L., et al., (1999) “lg V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia”, Blood 94, 1840–1847.
   PubMed Web of Science ®Google Scholar
• Juliusson, G., Oscier, D.G., Fitchett, M., Ross, F.M., Stockdill, G., Mackie, M.J., et al., (1990) “Prognostic subgroups in B-cell chronic lymphocytic leukemia defined by specific chromosomal abnormalities”, N. Engl. J. Med. 323, 720–724.
   PubMed Web of Science ®Google Scholar
• A conference on the morphologic, immunologic, and cytogenetic classification of the chronic (mature) B and T lymphoid leukemia: (MIC IV). Cancer Genet. Cytogenet. 48 (1990) pp. 131–132.
   Google Scholar
• Stilgenbauer, S., Lichter, P. and Döhner, H. (2000) “Genetic features of B-cell chronic lymphocytic leukemia”, Rev. Clin. Exp. Hematoi. 4, 48–72.
   PubMedGoogle Scholar
• Johansson, B., Mertens, F. and Mitelman, F. (1993) “Cytogenetic deletion, maps of hematologic neoplasms: circumstantial evidence for tumor suppressor loci”, Genes Chromosomes Cancer 8, 205–218.
   PubMed Web of Science ®Google Scholar
• Raffeid, M. and Jaffe, E.S. (1991) “Bcl-1, t(11;14), and mantle cell-derived lymphomas”, Blood 78, 259–263.
   PubMed Web of Science ®Google Scholar
• EI Rouby, S., Thomas, A., Costin, D., Rosenberg, C.R., Potmesil, M., Silber, R. and Newcombe, E.W. (1993) “p53 Gene mutation in B-cell chronic lymphocytic leukaemia is associated with drug resistance and is independent of MDR1/MDR3 gene expression”, Blood 82, 3452–3459.
   PubMed Web of Science ®Google Scholar
• Howe, D.J., Bromidge, T.J., Stack-Dunne, M., Davies, S.V., Paxton, A., Phillips, M.J., et al, (1997) “Trisomy 12 is a rare event in cases of CLL with typical immunophenotype and morphology”, Hematology 2, 373–378.
   PubMedGoogle Scholar
• Solinas-Toldo, S., Lampel, S., Stilgenbauer, S., Nickolenko, J., Benner, A., Döhner, H., et al., (1997) “Matrix-based comparative genomic hybridization: biochips to screen for genomic imbalances”, Genes Chromosomes Cancer 20, 399–407.
   PubMed Web of Science ®Google Scholar
• Hallek, M. (2000) “New concepts in the pathogenesis, diagnosis, prognostic factors and clinical presentation of chronic lymphocytic leukemia”, Rev. Clin. Exp. Hematoi. 4,103–117.
   Google Scholar
• Myint, H., Copplestone, J.A., Orchard, J., Craig, V., Curtis, D., Prentice, A.G., et al., (1995) “Fludarabine-related autoimmune haemolytic anaemia in patients with chronic lymphocytic leukaemia”, Br. J. Haematol. 91, 341–344.
   PubMed Web of Science ®Google Scholar
• Apostolopoulos, A., Symeonidis, A. and Zoumbos, N. (1990) “Prognostic significance of immune function parameters in patients with chronic lymphocytic leukaemia”, Eur. J. Haematol. 44, 39–44.
   PubMed Web of Science ®Google Scholar
• Orsini, E., Guarini, A. and Foa, R. (2000) “Accessory cells, cytokine loops and cell-to-cell interactions in chronic lymphocytic leukemia”, Rev. Clin. Exp. Hematoi. 4, 73–98.
   PubMedGoogle Scholar
• Liu, Y.J., Joshua, D.E., Williams, G.T., Smith, C.A., Gordon, J. and MacLennan, I.C. (1989) “Mechanism of antigen-driven selection in germinal centres”, Nature 342, 929–931.
   PubMed Web of Science ®Google Scholar
• Keating, M.J. and O'Brien, S. (2000) “Conventional management of chronic lymphocytic leukemia”, Rev. Clin. Exp. Hematoi. 4, 118–133.
   Google Scholar
• Catovsky, D., Fooks, J. and Richards, S. (1989) “Prognostic factors in chronic lymphocytic leukaemia: the importance of age, sex and response to treatment in survival. A report from the MRC CLL 1, Trial”, Br. J. Haematol. 72, 141–149, for the MRC Working Party on Leukaemia in Adults.
   PubMed Web of Science ®Google Scholar
• Keating, M.J., Kantarjian, H., Talpaz, M., Redman, J., Koller, C., Barlogie, B., et al., (1989) “Fludarabine: a new agent with major activity against chronic lymphocytic leukemia”, Blood 74, 19–25.
   PubMed Web of Science ®Google Scholar
• Colby, C, McAfee, S.L., Sackstein, R., Finkelstein, D.M., Fishman, J.A. and Spitzer, T.R. (1999) “A prospective randomised trial comparing the toxicity and safety of atovaquone with trimethoprim/sulfamethoxazole as Pneumocystis carinii prophylaxis following autologous peripheral blood stem cell transplantation”, Bone Marrow Transplant. 24, 897–902.
   PubMed Web of Science ®Google Scholar
• Bellosillo, B., Villamor, N., Colomer, D., Pons, G., Montserrat, E. and Gil, J. (1999) “In vitro evaluation of fludarabine in combination with cyclophosphamide and/or mitoxantrone in B-cell chronic lymphocytic leukemia”, Blood 94, 2836–2843.
   PubMed Web of Science ®Google Scholar
• The French Cooperative Group on CLLJohnson, S., Smith, A.G., Löffler, H., Ösby, E., Juliusson, G., et al., (1996) “Multicentre prospective randomised trial of fludarabine versus cyclophosphamide, doxorubicin, and prednisone (CAP) for treatment of advanced-stage chronic lymphocytic leukaemia”, Lancet 347, 1432–1438.
   PubMed Web of Science ®Google Scholar
• Jacobs, P. and King, H.S. (1987) “A randomised prospective comparison of chemotherapy to total body irradiation as initial treatment for the indolent lymphoproliferative diseases”, Blood 69, 1642–1646.
   PubMed Web of Science ®Google Scholar
• Kipps, T.J. (1997) “Chronic lymphocytic leukemia”, Curr. Opin. Hematoi. 4, 268–276.
   PubMedGoogle Scholar
• Campath users' meeting 2000 (in press).
   Google Scholar
• Keating, M.J., O'Brien, S., Lerner, S., Koller, C., Beran, M., Robertson, L.E., et al., (1998) “Long-term follow-up of patients with chronic lymphocytic leukemia (CLL) receiving fludarabine regimens as initial therapy”, Blood 92, 1165–1171.
   PubMed Web of Science ®Google Scholar
• Österborg, A., Fassas, A.S., Anagnostopouios, A., Dyer, M.J.S., Catovsky, D and Mellstedt, H. (1996) “Humanized CD52 monoclonal antibody Campath-1H as first-line treatment in chronic lymphocytic leukaemia”, Br. J. Haematol. 93, 151–153.
   PubMed Web of Science ®Google Scholar
• Rai, K.R. and Gupta, N. (2000) “Monoclonal antibodies in chronic lymphocytic leukemia”, Rev. Clin. Exp. Hematoi. 4, 134–144.
   Google Scholar
• Cheson, B.D., Dancey, J. and Murgo, A. (2000) “New drugs for the treatment of chronic lymphocytic leukemia”, Rev. Clin. Exp. Hematol. 4, 145–166.
   Google Scholar
• Neal, Jr, T.F., Tefferi, A., Witzing, T.E., Su, J., Phyliky, R.L. and Nagorney, D.M. (1992) “Splenectomy in advanced chronic lymphocytic leukemia: a single institution experience with 50 patients”, Am. J. Med. 93, 435–440.
   PubMed Web of Science ®Google Scholar
• Michallet, M., Archimbaud, E., Bandini, G., Rowlings, P.A., Deeg, H.J., Gahrton, G., et al., (1996) “HLA-identical sibling bone marrow transplantation in younger patients with chronic lymphocytic leukemia”, Ann. Intern. Med. 124, 311–315.
   PubMed Web of Science ®Google Scholar
• Esteve, J., Villamor, N., Colomer, D., Bosch, F., López-Guillermo, A., Rovira, M., et al., (1998) “Hematopoietic stem cell transplantation in chronic lymphocytic leukemia: a report 12 patients from a single institution”, Ann. Oncol. 9,167–172.
   PubMed Web of Science ®Google Scholar
• Waselenko, J. K., Flynn, J.M. and Byrd, J.C. (1999) “Stem-cell transplantation in chronic lymphocytic leukemia: the time for designing randomised studies has arrived”, Semin. Oncol. 26, 48–61.
   PubMed Web of Science ®Google Scholar
• Dreger, P., Michallet, M. and Schmitz, N. (2000) “Stem-cell transplantation for chronic lymphocytic leukemia: the 1999 perspective”, Ann. Oncol. 11(Suppl. 1), S49–S53.
   PubMedGoogle Scholar
• Esteve, J. and Montserrat, E. (2000) “Hematopoietic stem-cell transplantation for B-cell chronic lymphocytic leukemia: current status”, Rev. Clin. Exp. Hematol. 4,167–178.
   Google Scholar
• Jacobs, P., Wood, L., Fullard, L., Waldmann, H. and Hale, G. (1994) “T cell depletion by exposure to Campath-1G in vitro prevents graft-versus-host disease”, Bone Marrow Transplant. 13, 763–769.
   PubMed Web of Science ®Google Scholar
• Jacobs, P. (1997) “Myelodsyplasia and the leukemias”, Disease-a-Month 43, 505–600.
   PubMed Web of Science ®Google Scholar