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Hematology Volume 8, 2003 - Issue 2
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Research Article

Role of Plasminogen Activator Inhibitor-1 (PAI-1) Levels in the Diagnosis of BMT-associated Hepatic Veno-occlusive Disease and Monitoring of Subsequent Therapy with Defibrotide (DF)

M. KaleelrahmanDepartments of Medical Oncology and HaematologyChristie Hospital, Wilmslow Rd, Manchester, UK
,
J.D. EatonDepartments of Medical Oncology and HaematologyChristie Hospital, Wilmslow Rd, Manchester, UK
,
D. LeemingThrombosis Reference Centre, Withington Hospital, Manchester, UK
,
K. BowyerDepartments of Medical Oncology and HaematologyChristie Hospital, Wilmslow Rd, Manchester, UK
,
D. TabernerThrombosis Reference Centre, Withington Hospital, Manchester, UK
,
J. ChangDepartments of Medical Oncology and HaematologyChristie Hospital, Wilmslow Rd, Manchester, UK
,
J.H. ScarffeDepartments of Medical Oncology and HaematologyChristie Hospital, Wilmslow Rd, Manchester, UK
&
R. ChopraDepartments of Medical Oncology and HaematologyChristie Hospital, Wilmslow Rd, Manchester, UK
 show all
Pages 91-95 | Published online: 04 Sep 2013

References

  • Salat, C., Holler, E., Hans-Jochem, K., Brigitte, R., Pihusch, R., Wolfgang, W. and Hiller, E. (1997) "Plasminogen activator inhibitor 1 confirms the diagnosis of hepatic veno-ocdusive disease in patients with hyper bilirubinemia after bone marrow transplant", Blood 89, 2184.
  • Richardson, P.G., Elias, A.D., Krishnan, A., Wheeler, C., Nath, R., Hoppensteadt, D., Kinchla, N.M., Neuberg, D., Waller, E.K., Antin, J.H., Soiffer, R., Vredenburgh, J., LiIli, M., Woolfrey, A.E., Bearman, S.I., Iacobelli, M., Jawed, Famed and Guinan, E.C. (1998) "Treatment of severe veno-ocdusive disease with Defibrotide: compassionate use results in response without significant toxicity in a high-risk popu-lation", Blood 92, 737–744.
  • Chopra, R. and Eaton, J.D. (2000) "Defibrotide for the treatment of hepatic veno-occlusive disease: results of the European compassionate use study", Br. J. Haematol. 111, 1122–1129.
  • Jones, R.J., Lee, K.S.K., Beschorner, W.E., Vogel, V.G., Grochow, L.B., Braine, H.G., Vogelsang, G.B., Sensenbrenner, L.L., Santos, G.W. and Sarel, R. (1987) "Venocclusive disease of the liver following bone marrow transplantation", Transplantation 44, 778–783.
  • Mcdonald, G.B., Hinds, M.S., Fisher, L.D., Schoch, H.G., Wolford, J.L., Banaji, M., Hardin, B.J., Shulman, H.M. and Clift, R.A. (1993) "Veno-occlusive disease of the liver and multiorgan failure after bone marrow transplan-tation: a cohort study of 355 patients", Ann. Intern. Med. 118, 225.
  • Bearman, S.I., Anderson, G.L., Mori, M., Hinds, MS., Shulman, H.M. and Mcdonald, G.B. (1993) "Veno-occlusive disease of the liver: development of a model for predicting fatal outcome after marrow transplantation", J. Clin. Oncol. 11, 1729.
  • Bearman, S.I. (1995) "The syndrome of hepatic veno-occlusive disease after marrow transplantation", Blood 85, 3005.
  • Carreras, E., Granena, A., Navasa, M., Bruguera, M., Marco, V, Sierra, J., Tassies, M.D., Garcia-Pegan, J-C., Marti, J.-M., Bosch, J., Rodes, J. and Rozman, C. (1993) "Transjugular liver biopsy in BMT", Bone Marrow Transplant. 11, 21.
  • Scrobohaci, M.L., Drouet, L., Monem-Mansi, A., Devergie, A., Maudin, B., D'Agay, M.F. and Gluckman, E. (1991) "Liver veno-occlusive disease after bone marrow transplantation changes in coagulation parameters and endothelial markers", Thromb. Res. 63, 509.
  • Faioni, E.M., Krachmalnikoff, A. and Bearman, S.I. (1993) "Naturally occurring anticoagulants and bone-marrow transplantation: plasma protein C predicts the development of veno-occlusive disease of the liver", Blood 81, 3458.
  • Palmer, K.J. and Goa, K.L. (1993) "Defibrotide: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in vascular disorders", Drugs 45, 259.

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