Gfi-1 Oncoproteins in Hematopoiesis

References

• Akashi, K., Traver, D., Miyamoto, T. and Weissman, I.L. (2000) "A clonogenic common myeloid progenitor that gives rise to all myeloid lineages", Nature 404, 193–197.
   PubMed Web of Science ®Google Scholar
• Orkin, S.H. (2000) "Diversification of haematopoietic stem cells to specific lineages", Nat. Rev. Genet. 1, 57–64.
   PubMed Web of Science ®Google Scholar
• Friedman, A.D. (2002) "Transcriptional regulation of granulo-cyte and monocyte development", Oncogene 21, 3377–3390.
   PubMed Web of Science ®Google Scholar
• Gilks, C.B., Bear, SE., Grimes, H.L. and Tsichlis, P.N. (1993) "Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein", Mol. Cell. Biol. 13, 1759–1768.
   PubMed Web of Science ®Google Scholar
• Roberts, T. and Cowell, J.K. (1997) "Cloning of the human Gfi-1 gene and its mapping to chromosome region 1p22", Oncogene 14, 1003–1005.
   PubMed Web of Science ®Google Scholar
• Zornig, M., Schmidt, T., Karsunky, H., Grzeschiczek, A. and Moroy, T. (1996) "Zinc finger protein GFI-1 cooperates with myc and pim-1 in T-cell lymphomagenesis by reducing the requirements for IL-2", Oncogene 12, 1789–1801.
   PubMed Web of Science ®Google Scholar
• Fuchs, B., Wagner, T., Rossel, N., Antoine, M., Beug, H. and Niessing, J. (1997) "Structure and erythroid cell-restricted expression of a chicken cDNA encoding a novel zinc finger protein of the Cys + His class", Gene 195, 277–284.
   PubMed Web of Science ®Google Scholar
• Kasai, S. and Scott, J.G. (2001) "A house fly gene homologous to the zinc finger proto-oncogene Gfi-1", Biochem. Biophys. Res. Commun. 283, 644–647.
   PubMed Web of Science ®Google Scholar
• Nolo, R., Abbott, L.A. and Benen, H.J. (2000) "Senseless, a Zn finger transcription factor, is necessary and sufficient for sensory organ development in Drosophila", Cell 102, 349–362.
   PubMed Web of Science ®Google Scholar
• Jia, Y, Xie, G., McDermott, J.B. and Aamodt, E. (1997) "The C. elegans gene pag-3 is homologous to the zinc finger proto-oncogene gfi-1", Development 124, 2063–2073.
   PubMed Web of Science ®Google Scholar
• Bell, D.W., Taguchi, T., Jenkins, N.A., Gilbert, D.J., Copeland, N.G., Gilks, C.B., Zweidler-McKay, P., Grimes, H.L., Tsichlis, P.N. and Testa, J.R. (1995) "Chromosomal localization of a gene, GF1, encoding a novel zinc finger protein reveals a new syntenic region between man and rodents", Cytogenet. Cell. Genet. 70, 263–267.
   PubMedGoogle Scholar
• Tong, B., Grimes, H.L., Yang, T.Y., Bear, S.E., Qin, Z., Du, K., El-Deiry, W.S. and Tsichlis, P.N. (1998) "The Gfi-1B proto-oncoprotein represses p21WAF1 and inhibits myeloid cell differentiation", Mol. Cell. Biol. 18, 2462–2473.
   PubMed Web of Science ®Google Scholar
• Rodel, B., Wagner, T., Zornig, M., Niessing, J. and Moroy, T. (1998) "The human homologue (GFI1B) of the chicken GFI gene maps to chromosome 9q34.13—A locus frequently altered in hematopoietic diseases", Genomics 54, 580–582.
   PubMed Web of Science ®Google Scholar
• Zweidler-Mckay, P.A., Grimes, H.L., Flubacher, M.M. and Tsichlis, P.N. (1996) "Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor", Mol. Cell. Biol. 16, 4024–4034.
   PubMed Web of Science ®Google Scholar
• Grimes, H.L., Chan, TO., Zweidler-McKay, P.A., Tong, B. and Tsichlis, P.N. (1996) "The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal", Mol. Cell. Biol. 16, 6263–6272.
   PubMed Web of Science ®Google Scholar
• Katoh, M. (2003) "Identification and characterization of human SNAIL3 (SNAI3) gene in silico", Int. J. Mol. Med. 11, 383–388.
   PubMed Web of Science ®Google Scholar
• Cameron, S., Clark, S.C., McDermott, J.B., Aamodt, E. and Horvitz, H.R. (2002) "PAG-3, a Zn-finger transcription factor, determines neuroblast fate in C. elegans", Development 129, 1763–1774.
   PubMed Web of Science ®Google Scholar
• Schmidt, T., Zornig, M., Beneke, R. and Moroy, T. (1996) "MoMuLV proviral integrations identified by Sup-F selection in tumors from infected myc/pim bitransgenic mice correlate with activation of the Gfi-1 gene", Nucleic. Acids Res. 24, 2528–2534.
   PubMed Web of Science ®Google Scholar
• Schmidt, T., Karsunky, H., Gau, E., Zevnik, B., Elsasser, H.P. and Moroy, T. (1998) "Zinc finger protein GFI-1 has low oncogenic potential but cooperates strongly with pim and myc genes in T-cell lymphomagenesis", Oncogene 17, 2661–2667.
   PubMed Web of Science ®Google Scholar
• Schmidt, T., Karsunky, H., Rodel, B., Zevnik, B., Elsasser, H.P. and Moroy, T. (1998) "Evidence implicating Gfi-1 and Pim-1 in pre-T-cell differentiation steps associated with beta-selection", Embo. J. 17, 5349–5359.
   PubMed Web of Science ®Google Scholar
• Scheijen, B., Jonkers, J., Acton, D. and Berns, A. (1997) "Characterization of pal-1, a common proviral insertion site in murine leukemia virus-induced lymphomas of c-myc and Pim-1 transgenic mice", J. Virol. 71, 9–16.
   PubMed Web of Science ®Google Scholar
• Rodel, B., Tavassoli, K., Karsunky, H., Schmidt, T., Bachmann, M., Schaper, F., Heinrich, P., Shuai, K., Elsasser, H.P. and Moroy, T. (2000) "The zinc finger protein Gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3", Embo. J. 19, 5845–5855.
   PubMed Web of Science ®Google Scholar
• Doan, L.L., Kitay, M.K., Yu, Q., Singer, A., Herblot, S., Hoang, T., Bear, SE., Morse, 3rd, H.C., Tsichlis, P.N. and Grimes, H.L. (2003) "Growth factor independence-1B expression leads to defects in T cell activation, IL-7 receptor alpha expression, and T cell lineage commitment", J. Immunol. 170, 2356–2366.
   PubMed Web of Science ®Google Scholar
• Grimes, H.L., Gilks, C.B., Chan, TO., Porter, S. and Tsichlis, P.N. (1996) "The Gfi-1 protooncoprotein represses Bax expression and inhibits T-cell death", Proc. Natl Acad. Sci. USA 93, 14569–14573.
   PubMed Web of Science ®Google Scholar
• Karsunky, H., Mende, I., Schmidt, T. and Moroy, T. (2002) "High levels of the onco-protein Gfi-1 accelerate T-cell proliferation and inhibit activation induced T-cell death in Jurkat T-cells", Oncogene 21, 1571–1579.
   PubMed Web of Science ®Google Scholar
• Zhu, J., Guo, L., Min, B., Watson, C.J., Hu-Li, J., Young, H.A., Tsichlis, P.N. and Paul, W.E. (2002) "Growth factor independent-1 induced by IL-4 regulates Th2 cell prolifer-ation", Immunity 16, 733–744.
   PubMed Web of Science ®Google Scholar
• Karsunky, H., Zeng, H., Schmidt, T., Zevnik, B., Kluge, R., Schmid, K.W., Duhrsen, U. and Moroy, T. (2002) "Inflamma-tory reactions and severe neutropenia in mice lacking the transcriptional repressor Gfi1", Nat. Genet. 30, 295–300.
   PubMed Web of Science ®Google Scholar
• Hock, H., Hamblen, M.J., Rooke, H.M., Traver, D., Bronson, R.T., Cameron, S. and Orkin, S.H. (2003) "Intrinsic require-ment for zinc finger transcription factor Gfi-1 in neutrophil differentiation", Immunity 18, 109–120.
   PubMed Web of Science ®Google Scholar
• Person, R.E., Li, EQ., Duan, Z., Benson, K.F., Wechsler, J., Papadaki, H.A., Eliopoulos, G., Kaufman, C., Bertolone, S.J., Nakamoto, B., Papayannopoulou, T., Grimes, H.L. and Horwitz, M. (2003) "Mutations in proto-oncogene GFI1 cause human neutropenia and target ELA2", Nat. Genet. 34, 308–312.
   PubMed Web of Science ®Google Scholar
• Yucel, R., Karsunky, H., Klein-Hitpass, L. and Moroy, T. (2003) "The transcriptional repressor Gfi1 affects development of early, uncommitted c-Kit + T cell progenitors and CD4/CD8 lineage decision in the thymus", J. Exp. Med. 197, 831–844.
   PubMed Web of Science ®Google Scholar
• Dale, D.C., Person, R.E., Bolyard, A.A., Aprikyan, A.G., Bos, C., Bonilla, M.A., Boxer, L.A., Kannourakis, G., Zeidler, C., Welte, K., Benson, K.F. and Horwitz, M. (2000) "Mutations in the gene encoding neutrophil elastase in congenital and cyclic neutropenia", Blood 96, 2317–2322.
   PubMed Web of Science ®Google Scholar
• Horwitz, M., Benson, K.F., Person, R.E., Aprikyan, A.G. and Dale, D.C. (1999) "Mutations in ELA2, encoding neutrophil elastase, define a 21-day biological clock in cyclic haemato-poiesis", Nat. Genet. 23, 433–436.
   PubMed Web of Science ®Google Scholar
• Horwitz, M., Benson, K.F., Duan, Z., Person, R.E., Wechsler, J., Williams, K., Albani, D. and Li, F.Q. (2003) "Role of neutrophil elastase in bone marrow failure syndromes: molecular genetic revival of the chalone hypothesis", Curr. Opin. Hematol. 10, 49–54.
   PubMed Web of Science ®Google Scholar
• Saleque, S., Cameron, S. and Orkin, S.H. (2002) "The zinc-finger proto-oncogene Gfi-1b is essential for development of the erythroid and megakaryocytic lineages", Genes Dev. 16, 301–306.
   PubMed Web of Science ®Google Scholar
• Osawa, M., Yamaguchi, T., Nakamura, Y., Kaneko, S., Onodera, M., Sawada, K., Jegalian, A., Wu, H., Nakauchi, H. and Iwama, A. (2002) "Erythroid expansion mediated by the Gfi-1B zinc finger protein: role in normal hematopoiesis", Blood 100, 2769–2777.
   PubMed Web of Science ®Google Scholar
• Duan, Z. and Horwitz, M. (2003) "Targets of the transcrip-tional repressor oncoprotein Gfi-1", Proc. Nat! Acad. Sci. USA 100, 5932–5937.
   PubMed Web of Science ®Google Scholar
• Zhang, D.E., Zhang, P., Wang, N.D., Hetherington, C.J., Darlington, G.J. and Tenen, D.G. (1997) "Absence of granulocyte colony-stimulating factor signaling and neutro-phil development in CCAAT enhancer binding protein alpha-deficient mice", Proc. Nat! Acad. Sci. USA 94, 569–574.
   PubMed Web of Science ®Google Scholar
• Yamanaka, R., Barlow, C., Lekstrom-Himes, J., Castilla, L.H., Liu, P.P., Eckhaus, M., Decker, T., Wynshaw-Boris, A. and Xanthopoulos, K.G. (1997) "Impaired granulopoiesis, myelo-dysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice", Proc. Nat! Acad. Sci. USA 94, 13187–13192.
   PubMed Web of Science ®Google Scholar
• Klappacher, G.W., Lunyak, V.V., Sykes, D.B., Sawka-Verhelle, D., Sage, J., Brard, G., Ngo, S.D., Gangadharan, D., Jacks, T., Kamps, M.P., Rose, D.W., Rosenfeld, M.G. and Glass, C.K. (2002) "An induced Ets repressor complex regulates growth arrest during terminal macrophage differentiation", Cell 109, 169–180.
   PubMed Web of Science ®Google Scholar
• Lessard, J. and Sauvageau, G. (2003) "Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells", Nature 423, 255–260.
   PubMed Web of Science ®Google Scholar
• Park, I.K., Qian, D., Kiel, M., Becker, M.W., Pihalja, M., Weissman, IL., Morrison, S.J. and Clarke, M.F. (2003) "Bmi-1 is required for maintenance of adult self-renewing haemato-poietic stem cells", Nature 423, 302–305.
   PubMed Web of Science ®Google Scholar
• Nakagawa, K. and Yokosawa, H. (2002) "PIAS3 induces SUMO-1 modification and transcriptional repression of IRF-1", FEBS Lett. 530, 204–208.
   PubMed Web of Science ®Google Scholar
• Wallis, D., Hamblen, M., Zhou, Y., Venken, K.J., Schumacher, A., Grimes, H.L., Zoghbi, H.Y., Orkin, S.H. and Bellen, H.J. (2003) "The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival", Development 130, 221–232.
   PubMed Web of Science ®Google Scholar