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Hemostasis and Thrombosis

The effect of 5-hydroxtryptamine on the regulation of megakaryocytopoiesis

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Pages 53-56 | Published online: 04 Sep 2013

References

  • Nemecek GM, Coughlin SR, Handley DA, Moskowitz MA. Stimulation of aortic-smooth muscle cell mitogenesis by serotonin. Proc Natl Acad Sci USA 1986;83:674–678.
  • Yang M, Sridiatkhachorn A, Anthony M, Chong BH. Serotonin stimulates megakaryocytopoiesis via 5HT2 recep-tors. Blood Coagul Fibrin 1996;6:127–133.
  • Yang M, Li K, Chuen CKY, Pong NH, et al. Serotonin is a growth factor for megakaryocytopoiesis. Blood 2003; 102(11):2918.
  • Lee SL, Wang WW, Fanburg BL. Superoxide as an intermediate signal for serotonin-induced mitogenesis. Free Radic Biol Med 1998;24:855–858.
  • Lee SL, Wang WW, et al. Superoxide scavenging effect of Ginkgo biloba extracton serotonin-induced mitogenesis. Bio-chem Pharmacol 1998;56:527–533.
  • Warden SJ, Robling AJ, et al. Inhibition of the serotonin (5-Hydroxytryptamine) transporter reduces bone accrual during growth. Endocrinology 2005;146:685–693.
  • Vesela J, Rehak P, Mihalik J, et al. Expression of serotonin receptors in mouse oocytes and preimplantation embryos. Physiol Res 2003;52(2):223–228.
  • Choi DS, Ward SJ, Messaddeq N, et al. 5-HT2B receptor-mediated serotonin morphogenetic functions in mouse cranial neural crest and myocardiac cell. Development 1997124:1745-1755.
  • Nebigil CG, Choi DS, et al. Serotonin 2B receptor is required for heart development. PNAS 2000;97:9508–9513.
  • Yang M, Li K, Chuen CKY, et al. An alternative growth factor for hematopoietic stem cells and megakaryocytopoiesis. Blood 2004;104(11):2060.
  • Rothman BR, Baumann MH, et al. Evidence for possible involvement of 5-HT2B receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medi-cations. Circulation 2000;102:2836–2841.
  • Howells EF, Maroteaux L, Gershon MD. Serotonin and the 5-HT2B receptor in the development of enteric neurons. J Neurosci 2000;20: 294–305.
  • Westbroek I, Plas AVD, et al. Expression of serotonin receptors in bone. J Biol Chem 2001;276:28961–28968.
  • Seuwen K, Magnaldo I, Pouyssegur J. Serotonin stimulates DNA synthesis in fibroblasts acting through 5-HT1B receptors coupled to a Gi-protein. Nature 1988; 335(6187):254–256.
  • Grewal JS, Mukhin YV, et al. Serotonin 5-HT2A receptor induces TGF-131 expression in mesangial cells via ERK: Proliferative and fibrotic signals. Am J Physiol Renal Physiol 1999;276:922–930.
  • Deniau IG, Burnol AF, Girard J. Identification and localization of a skeletal muscle secrotonin 5-HT2A receptor coupled to the Jak/STAT pathway. J Biol Chem 1997;272: 14825–14829.
  • Nebigil CG, Launay MJ, et al. 5-Hydroxytryptamine 2B receptor regulates cell-cycle progression: Cross-talk with tyrosine kinase pathways. PNAS 2000;97:2591–2596.
  • Lee SL, Wang WW, et al. Serotonin stimulates mitogen-activated protein kinase activity through the formation of superoxide anion. Am J Physiol Lung Cell Mol Physiol 1999;277:282–291.
  • Lee SL, Simon AR, Wang WW, et al. H202 signals 5-HT-induced ERK MAP kinase activation and mitogenesis of smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2001;281:646–652.
  • Greene EL, Houghton O, Collinsworth G, et al. 5-HT2A receptors stimulate mitogenactivated protein kinase via H202 generation in rat renal mesangial cells. Am J Physiol Renal Physiol 2000;278:F650–F658.
  • Liu YL, Suzuki YJ, Day RNI, et al. Rho kinase-induced nuclear translocation of ERK1/ERK2 in smooth muscle cell mitogen-esis caused by serotonin. Circ Res 2004;95(6):579–586.
  • Yang M, Srikiathchorn A, Anthony M, Chesterman CN, Chong BH. Serotonin uptake, storage and metabolism in megakaryoblasts. hit J Hematol 1996;63:137–142.
  • Yang M, Li K, Yuen PMP, Pong NH, Wong R, Chik KW, Li CK, Shing MMK, Fok TF. Identification of 5-HT2A, 5-HT2B and 5-HT2C receptors on human megakaryocytes and megakaryocytic cell lines. Thromb Haemost 2001:311.
  • Yang M, Yuen PMP, Li K, et al. New link between megakaryocytopoiesis and neurotransmitter 5-HT. Blood 2002;100:1880.
  • Sung R, Yang M, Yi Q, Li K, et al. Serotonin has a promoting effect on the proliferation of bone marrow stromal cells. Exp Hematol Suppl. (1) 2003;31(7):224–225, 493.
  • Yang M, Li K, Lam AC, et al. Platelet-derived growth factor enhances granulopoiesis via bone marrow stromal cells. Int J Hematol 2001;73(3):327–334.
  • Yang M, Khachigian LM, Hicks C, et al. Identification of PDGF receptors on human megakaryocytes and megakaryo-cytic cell lines. Thromb Haemost 1997;78(2):892–896.
  • Yang M, Chesterman CN, Chong BH. Recombinant PDGF enhances megakaryocytopoiesis in vitro. Br J Haematol 1995;91 (2):285–289.
  • Su RJ, Li K, Zhang XB, Yang M, et al. Platelet-derived growth factor enhances ex vivo expansion of CD34+ cells from human cord blood. Br J Haematol 2002;117:735–746.
  • Chui CMY, Li K, Yang M, et al. Platelet-derived growth factor up-regulates the expression of transcription factors NF-E2, GATA-1 and c-Fos in megakaryocytic cell lines. Cytokine 2003;21(2):51–64.
  • Turkina AG, Khoroshko ND, et al. Therapeutic efficacy of imatinib mesylate (glivec) in chronic phase of myeloid leukaemia. Ter-Arldi 2003;75 (8):62–67.
  • Yang M, Li K, Yuen PMP, et al. Thrombospondin-1 inhibits in vitro megakaryocytopoiesis via CD36. Thromb Res 2003; 109(1):47–54.
  • Battinelli E, Loscalzo J. Nitro oxide induces apoptosis in megakaryocytic cell lines. Blood 2000;95:3451–3459.
  • Yang M, Hogg PJ, Chisholm OT, Li K, Chesterman CN, Chong BH. TSP1 inhibits PEG-rHuMGDF-induced mega-karyocytopoiesis via TSP/TSP receptor interaction. Blood 1999;94(10):41a.

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