115
Views
9
CrossRef citations to date
0
Altmetric
Acute Leukaemia

Impact of FLT3 internal tandem duplications on Indian acute promyelocytic leukemia patients: Prognostic implications

, , , , , , & show all
Pages 99-101 | Published online: 04 Sep 2013

References

  • Rosnet O, Schiff C, Pebusque MJ, Marchetto S, Tonnelle C, Toiron Y, et al. Human FLT3/FLK2 gene: cDNA cloning and expression in hematopoietic cells. Blood 1993;82:1110–1119.
  • Boissel N, Cayuela JM, Preudhomme C, Thomas X, Grardel N, Fund X, Tigaud I, et al. Prognostic significance of FLT3 internal tandem repeat in patients with denovo acute myeloid leukemia treated with reinforced courses of chemotherapy. Leukemia 200216:1699-1704.
  • Schnittger S, Schoch C, Dugas M, Kern W, Staib P, Wuchter C, Loftier H, Sauerland CM, et al. Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: Correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease. Blood 2002;100:59–66.
  • Kiyoi H, Naoe T, Yokota S, Nakao M, Minami S, Kuriyama K, Takeshita A, Saito K, et al. Internal tandem duplication of FLT3 associated with leukocytosis in acute promyelocytic leukemia. Leukemia study group of the ministry of health and welfare (Kohseisho). Leukemia 1997;11:1447–1452.
  • Sanz MA, Martin G, Rayon C, Esteve J, Gonzalez M, Diaz-Mediavilla J, Bolufer P, Barragan E, et al. A modified AIDA protocol with anthracycline based consolidation results in high antileukemic efficacy and reduced toxicity in newly diagnosed PML/RARA positive acute promyelocytic leukemia. Blood 1999;9:3015–3021.
  • Chomczynsky P, Sacchi N. Single step method of RNA isolation by acid guanidium thocyanate—phenol chloroform extraction. Anal Biochem 1987;162:156–159.
  • Borrow J, Goddard AD, Gibbons B, Katz F, Swirsky D, Fioretos T, Dube I, Winfield DA, et al. Diagnosis of acute promyelocytic leukemia by RT-PCR: Detection of PML—RARA and RARA—PML fusion transcripts. Br J Haematol 1992;82:529–540.
  • Noguera NI, Breccia M, Divona M, Diverio D, Costa V, De Santis S, et al. Alterations of the FLT3 gene in acute promyelocytic leucemia: Association with diagnostic charac-teristics and analysis of clinical outcome in patients treated with the Italian AIDA protocol. Leukemia 2002;16: 2185–2189.
  • Shih LY, Kuo MC, Liang DC, Huang CF, Lin TL, Wu JH, Wang PN, et al. Internal tandem duplication and Asp835 mutations of the FMS-like tyrosine kinase 3(FLT3) gene in acute promyelocytic leukemia. Cancer 2003;98:1206–1216.
  • Kainz B, Heintel D, Marculescu R, Schwarzinger I, Sperr W, Le T, Welterman A, Fontasch C, Haas OA, et al. Variable prognostic value of FLT3 internal tandem dulications in patients with denovo AML and a normal karyotype, t(15;17), t(8;21) or inv16. Hematol J 2002;3:283–289.
  • Grimdade D, Gale R, Hills R, Kottaridis P, Swirsky D, Gilkes A, Nugent E, Mills K. The relationship between FLT3 mutation status, biological characteristics and outcome in patients with acute promyelocytic leukemia. Blood 2003;102, (abstract no.334).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.