Nitrite and Nitrate Plasma Levels, as Markers for Nitric Oxide Synthesis, in Thrombotic Thrombocytopenic Purpura (TTP)

References

• Moschcowitz, E. (1925). An acute febrile pleiochromic anemia with hyaline thrombosis of the terminal arterioles and capillaries: an undescribed disease. Arch. Intern. Med., 36, 294–310.
   Google Scholar
• Berkowitz, L. R., Dalldorf, F. G. and Blatt, P. M. (1979). Thrombotic thrombocytopenic purpura: a pathology review. J. Am. Med. Assoc., 241, 1709–10.
   PubMed Web of Science ®Google Scholar
• Rose, M., Rowe, J. M. and Eldor, A. (1993). The changing course of thrombotic thrombocytopenic purpura and modem therapy. Blood Rev., 7, 94–103.
   PubMed Web of Science ®Google Scholar
• Vane, J. R. and Botting, R. M. (1991). Endothelium-thromboresistance. Wien. Klin. Wochenschr., 103, 403–4.
   PubMed Web of Science ®Google Scholar
• Ignarro, L. J., Buga, G. M., Wood, K. S., Byrnes, R. E. and Chauduri, G. (1987). Endothelium-derived relaxing factor produced and released from artery and veins is nitric oxide. Proc. Natl. Acad. Sci. U.S.A., 84, 9265–9.
   PubMed Web of Science ®Google Scholar
• Palmer, R. M., Ferrige, A. G. and Moncada, S. (1987). Nitric oxide release accounts for the biological activity of endothelial-derived relaxing factor. Nature, 327, 524–6.
   PubMed Web of Science ®Google Scholar
• Vanhoutte, P. M. and Eber, B. (1991). Endothelial-derived relaxing and contracting factors. Wien. Klin. Wochenschr., 103, 405–11.
   PubMed Web of Science ®Google Scholar
• Seligman, S. P., Buyon, J. R, Clancy, R. M., Young, B. K. and Abramson, S. B. (1994). The role of nitric oxide in the pathogenesis of preeclampsia. Am. J. Obstet. Gynecol., 171, 944–8.
   PubMed Web of Science ®Google Scholar
• Moncada, S., Palmer, R. M. and Higgs, E. A. (1991). Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol. Rev., 43, 109–42.
   PubMed Web of Science ®Google Scholar
• Furchgott, R. F. and Zawadzki, J. V. (1980). The obligatory role of endothelial cells in the relaxation or arterial smooth muscle by acetylcholine. Nature, 228, 373–6.
   Web of Science ®Google Scholar
• Ignarro, L. J., Byrns, R. E., Buga, G. M. and Wood, K. S. (1987). Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical. Circ. Res., 61, 866–79.
   PubMed Web of Science ®Google Scholar
• Van-Buren, G. A., Yang, D. S. and Clark, K. E. (1992). Estrogen-induced uterine vasodilation is antagonized by L-nitroarginine methyl ester, an inhibitor of nitric oxide synthesis. Am. J. Obstet. Gynecol., 167, 828–33.
   PubMed Web of Science ®Google Scholar
• Marietta, M. A., Yoon, P. S., Iyengar, R., Leaf, C. D. and Wishnok, J. S. (1988). Macrophage oxidation of L-argi-nine to nitrite and nitrate: nitric oxide is an intermediate. Biochemistry, 27, 8706–11.
   PubMed Web of Science ®Google Scholar
• Ochoa, J. B., Udekwu, A. O., Billiar, T. R., Curran, R. D., Cerra, F. B., Simmons, R. L. and Peitzman, A. B. (1991). Nitrogen oxide levels in patients after trauma and during sepsis. Ann. Surg., 214, 621–6.
   PubMed Web of Science ®Google Scholar
• Shultz, P. J. and Tolins, J. P. Adaptation to increased dietary salt intake in the rat: role of endogenous nitric oxide. J. Clin. Invest., 91, 642–50.
   PubMed Web of Science ®Google Scholar
• Rosselli, M., Imthum, B., Macas, E., Keller, P. J. and Dubey, R. K. (1994). Circulating nitrite/nitrate levels increase with follicular development: indirect evidence for estradiol mediated NO-release. Biochem. Biophys. Res. Commun., 202, 1543–52.
   PubMed Web of Science ®Google Scholar
• Hibbs, J. B., Westenfelder, C., Taintor, R., Vavrin, Z., Kablitz, C., Baranowski, R. L., Ward, J. H., Menlove, R. L., McMurry, M. P., Kushner, J. P. and Samlowski, W. E. (1992). Evidence for cytokine-inducible nitric oxide synthesis from L-arginine in patients receiving interleukin-2 therapy. J. Clin. Invest., 89, 867–77.
   PubMed Web of Science ®Google Scholar
• Evans, T. G., Ramussen, K., Webke, G. and Hibbs, J. B. Jr. (1994). Nitric oxide synthesis in patients with advanced HTV infection. Clin. Exp. Immunol., 97, 83–6.
   PubMed Web of Science ®Google Scholar
• Rosselli, M., Imthum, B., Keller, P. J., Jackson, E. K. and Dubey, R. K. (1995). Circulating nitric oxide (nitrite/nitrate) levels in postmenopausal women substituted with 17(β-estradiol and norethisterone acetate. Hypertension, 25 [part 2], 848–53.
   PubMedGoogle Scholar
• Stein, C., Classen, H. G. and Schwedt, G. (1988). Kinetic studies on nitrite and nitrate in rats by ion-pair chro-matography. Clinica Chimica Acta, 175, 167–74.
   PubMed Web of Science ®Google Scholar
• Winer, B. J., Brown, D. R. and Michels, K. M. (1991). Statistical principles in experimental design, 3rd edn, pp. 911–54. New York: McGraw-Hill.
   Google Scholar
• Rose, M. and Eldor, A. (1987). High incidence of relapses in thrombotic thrombocytopenic purpura. Clinical study of 38 patients. Am. J. Med., 83, 437–44.
   PubMed Web of Science ®Google Scholar
• Nathan, C. and Xie, Q. W. (1994). Regulation of the biosynthesis of nitric oxide. J. Biol. Chem., 269, 13725–8.
   PubMed Web of Science ®Google Scholar
• Marletta, M. A. (1993). Nitric oxide synthase structure and mechanism. J. Biol. Chem., 268, 12231–4.
   PubMed Web of Science ®Google Scholar
• Davies, R F., Olesen, S. P., Clapham, D. E., Morrel, E. M. and Schoen, F. J. (1988). Endothelial communications. Hypertension, 11, 563–72.
   PubMed Web of Science ®Google Scholar
• Nishimura, J. and Van Breemen, C. (1989). Direct regulation of smooth muscle contractile elements by second messengers. Biochem. Biophys. Res. Com., 163, 929–35.
   PubMed Web of Science ®Google Scholar
• Radomski, M. K. and Moncada, S. (1993). Regulation of vascular homeostasis by nitric oxide. Thromb. Haemost., 70, 36–41.
   PubMed Web of Science ®Google Scholar
• Radomski, M. K., Palmer, R. M. J. and Moncada, S. (1987). The anti-aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide. Br. J. Pharmacol. 92, 639–46.
   PubMed Web of Science ®Google Scholar
• Hyslop, S. and de Nucci, G. (1991). The mechanisms and significance of the coupled release of endothelium-derived relaxing factor (EDRF) and prostacyclin (PGI2) from endothelial cells. Wien. Klin. Wochenschr., 103, 422–34.
   PubMed Web of Science ®Google Scholar
• Wennmalm, Å. (1994). Endothelial nitric oxide and cardiovascular disease. J. Intern. Med., 235, 317–27.
   PubMed Web of Science ®Google Scholar
• Wu, K. K. (1992). Role of prostacyclin in the pathogenesis and therapy of thrombotic thrombocytopenic purpura. In: Hemolytic uremic syndrome and thrombotic thrombocytopenic purpura. Kaplan BS, Trompeter RS, Moake JL (eds), pp. 483–9, New York: Marcel Dekker Inc..
   Google Scholar
• Remuzzi, G., Marchesi, D., Misiani, R., Mecca, G., De Gaetano, G. and Donati, M. B. (1979). Familial deficiency of a plasma factor stimulating vascular prostacyclin activity. Thromb. Res., 16, 517–70.
   PubMed Web of Science ®Google Scholar
• Wu, K. K., Hall, E. R., Rossi, E. C. and Papp, A. C. (1985). Serum prostacyclin binding defects in thrombotic thrombocytopenic purpura. J. Clin. Invest., 75, 168–74.
   PubMed Web of Science ®Google Scholar
• Bobbio-Pallavicini, E., Porta, C., Tacconi, F., Gugliotta, L., Centurioni, R., Vianelli, N., Billio, A., Ascari, E. and the Italian Cooperative Group for TIP. (1994). Intravenous prostacyclin (as Epoprostenol) infusion in thrombotic thrombocytopenic purpura (TTP). Four case reports and review of the literature. Haematologica, 79, 429–37.
   PubMed Web of Science ®Google Scholar
• Radomski, M. K., Palmer, R. M. J. and Moncada, S. (1990). An L-arginine/nitric oxide pathway present in human platelets regulates aggregation. Proc. Natl. Acad. Sci. U.S.A., 87, 1193–7.
   PubMed Web of Science ®Google Scholar
• Radomski, M. K., Palmer, R. M. J. and Moncada, S. (1987). Endogenous nitric oxide inhibits human platelet adhesion to vascular endothelium. Lancet, 2, 1057–8.
   PubMed Web of Science ®Google Scholar
• Loscalzo, J. (1995). Nitric oxide and vascular disease. N. Engl. J. Med., 333, 251–3.
   PubMed Web of Science ®Google Scholar
• Wennmalm, Å., Benthin, G., Edlund, A., Jungersten, L., Kieler-Jensen, N., Lundin, S., Westfelt, U. N., Petersson, A. S. and Waagstein, F. (1993). Metabolism and excretion of nitric oxide in humans. An experimental and clinical study. Circ. Res., 73, 1121–7.
   PubMed Web of Science ®Google Scholar
• Evans, T., Carpenter, A., Kinderman, H. and Cohen, J. (1993). Evidence of increased nitric oxide production in patients with the sepsis syndrome. Circ. Shock, 41, 77–81.
   PubMedGoogle Scholar
• Shultz, P. J. and Raij, L. (1991). Endogenously synthe-sized nitric oxide prevent endotoxin-induced glomerular thrombosis, J. Clin. Invest., 90, 1718–25.
   Web of Science ®Google Scholar
• Wasserman, A. E. (1978). The nitric-nitrosamine situation: a review. Food Engl., 50, 110–6.
   Google Scholar