59
Views
3
CrossRef citations to date
0
Altmetric
Malignancy

Subsequential Alterations of Telomeric DNA Length Correlate with Cytogenetic Response in Chronic Myeloid Leukemia Treated with Interferon alpha

, , , , &
Pages 1-10 | Received 28 Feb 1999, Published online: 13 Jul 2016

References

  • Kantarjian, H. M., Deisseroth, A., Kurzrock, R., Estrov, Z. and Talpaz, M. (1993). Chronic myelogenous leukemia: A concise update. Blood, 82, 691–703.
  • Talpaz, M., Kantarjian, H. M., McCredie, K. B., Keating, M. J., Trujillo, J. and Gutterman, J. (1987). Clinical investigation of human alpha interferon in chronic myelogenous leukemia. Blood, 69, 1280–1288.
  • Kloke, O., Niederle, N., Qiu, J. Y., Wandl, U., Moritz, T., Nagel-Hiemke, M. and Opslks, B. (1993). Impact of interferon alpha-induced cytogenetic improvement on survival in chronic myelogenous leukaemia. Br J Haematol, 83, 399–403.
  • Ozer, H., George, S. L., Schiffer, C. A., Rao, K., Rao, P. N., Wurster-Hill, D. H., Arthur, D. D., Powell, B., Gottlieb, A., Peterson, B. A., Rai, K., Testa, J. R., LeBeau, M., Tantravahi, R. and Bloomfield, C. D. (1993). Prolonged subcutaneous administration of recombinant α2b interferon in patients with previously untreated Philadelphia chromosome-positive chronic-phase chronic myelogenous leukemia: effect on remission duration and survival: cancer and leukemia group B study 8583. Blood, 82, 2975–2984.
  • Allan, N. C., Richards, S. M. and Shepherd, P. C. A. (1995). UK medical research council randomized, multicentre trial of interferon-an1 for chronic myeloid leukaemia: improved survival irrespective of cytogenetic response. Lancet, 345, 1392–1397.
  • Moyzis, R. K., Buckingham, J. M., Cram, L. S., Dani, M., Deaven, L. L., Jones, M. D., Meyne, J., Ratliff, R. L. and Wu, J. R. (1988). A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes. Proc Natl Acad Sci USA, 85, 6622–6626.
  • Harley, C. B., Futcher, A. B. and Greider, C. W. (1990). Telomeres shorten during aging of human fibroblasts. Nature, 345, 458–460.
  • Allsopp, R. C., Vaziri, H., Patterson, C., Goldstein, S., Younglai, E. V., Futcher, A. B., Greider, C. W. and Harley, C. B. (1992). Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci USA, 89, 10114–10118.
  • Hastie, N. D., Dempster, M., Dunlop, M. G., Thompson, A. M., Green, D. K. and Allshire, R. C. (1990). Telomere reduction in human colorectal carcinoma and with aging. Nature, 346, 866–868.
  • Hiyama, E., Hiyama, K., Tatsumoto, N., Kodama, T., Shay, J. W. and Yokoyama, T. (1996). Telomerase activity in human intestine. Int J Oncol, 9, 453–458.
  • Lindsey, J., Mcgill, N. I., Lindsey, L. A., Green, D. K. and Cooke, H. J. (1991). In vivo loss of telomeric repeats with age in humans. Mutat Res, 256, 45–48.
  • Satoh, H., Hiyama, K., Takeda, M., Awaya, Y., Watanabe, K., Ihara, Y., Maeda, H., Ishioka, S. and Yamakido, M. (1996). Telomere shortening in peripheral blood cells was related with aging but not with white blood cell count, Jpn J Human Genet, 41, 413–417.
  • Vaziri, H., Dragowska, W., Allsopp, R. C., Thomas, T. E., Harley, C. B. and Lansdorp, P. M. (1994). Evidence for a mitotic clock in human hematopoietic stem cells: Loss of telomeric DNA with age. Proc Natl Acad Sci USA, 91, 9857–9860.
  • Chiu, C. P., Dragowska, W., Kim, N. W., Vaziri, H., Yui, J., Thomas, T. E., Harley, C. B. and Lansdorp, P. M.(1996). Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow. Stem Cell, 14, 239–248.
  • Iwama, H., Ohyashiki, K., Ohyashiki, J. H., Hayashi, S., Yahata, N., Ando, K., Toyama, K., Hoshika, A., Takasaki, M. and Shay, J. W. (1998). Telomere length and telomerase activity vary with age in peripheral blood cells obtained from normal individuals. Human Genet, 102, 397–402.
  • de Lange, T. (1995). Telomere dynamics and genome instability in human cancer. In Telomeres (eds) Blackburn, E. H., Greider, C. W., Cold Spring Harbor Lab Press, New York, 265–293.
  • Shay, J. W. (1995). Aging and cancer: are telomeres and telomerase the connection? Mol Med Today, 1, 378–384.
  • Shay, J. W., Werbin, H. and Wright, W. E. (1996). Telomeres and telomerase in human leukemias. Leukemia, 10, 1255–1261.
  • Ohyashiki, K., Ohyashiki, J. H., Fujimura, T., Kawakubo, K., Saito, M., Nakazawa, S. and Toyama, K. (1994). Telomere shortening in hematopoietic neoplasias is related to their genetic alterations but not replicative capability. Cancer Genet Cytogenet, 78, 64–67.
  • Ohyashiki, K., Ohyashiki, J. H., Iwama, H., Hayashi, S., Shay, J. W. and Toyama, K. (1996). Telomerase reactivation in leukemia cells. Int J Oncol, 8, 417–421.
  • Ohyashiki, K., Ohyashiki, J. H., Iwama, H., Hayashi, S., Shay, J. W. and Toyama, K. (1997). Telomerase activity and cytogenetic changes in chronic myeloid leukemia with disease progression. Leukemia, 11, 190–195.
  • Counter, C. M., Gupta, J., Harley, C. B., Leber, B. and Bacchetti, S. (1995). Telomerase activity in normal leukocytes and in hematologic malignancies. Blood, 85, 2315–2320.
  • Ohyashiki, J. H., Ohyashiki, K., Fujimura, T., Kawakubo, K., Shimamoto, T., Iwabuchi, A. and Toyama, K. (1994). Telomere shortening associated with disease evolution patterns in myelodysplastic syndromes. Cancer Res, 54, 3557–3560.
  • Ohyashiki, J. H., Ohyashiki, K., Iwama, H., Hayashi, S., Toyama, K. and Shay, J. W. (1997). Clinical implications of telomerase activity levels in acute leukemia. Clin Cancer Res, 3, 619–625.
  • Yamada, O., Oshimi, K., Motoji, T. and Mizoguchi, H. (1995). Telomeric DNA in normal and leukemic blood cells. J Clin Invest, 95, 1117–1123.
  • Fujimura, T. (1995). Telomere shortening in hematopoietic neoplasias and its clinical implications (in Japanese with English abstract). J Tokyo Med Coll, 53, 652–663.
  • Iwama, H., Ohyashiki, K., Ohyashiki, J. H., Hayashi, S., Ando, K., Shay, J. W. and Toyama, K. (1997). The relationship between telomere length and therapy-related cytogenetoc responses in chronic myeloid leukemia. Cancer, 79, 1552–1560.
  • ISCN. (1991). Guidelines for Cancer Cytogenetics: Supplement to An International System for Human Cytogenetic Nomenclature, F. Mitelman (ed); Basel, S. Karger.
  • Ohyashiki, J. H., Ohyashiki, K., Sano, T. and Toyama, K. (1996). Non-radioisotopic and simi-quantiative procedure for terminal repeat amplification protocol. Jpn J Cancer Res, 87, 329–331.
  • Ohyashiki, J. H., Ohyashiki, K., Toyama, K. and Shay, J. W. (1996). A non-radioactive, fluorescence-based telomeric repeat amplification protocol to detect and quantitate telomerase activity. Trends Genet, 12, 395–396.
  • Morin, G. B. (1989). The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell, 59, 521–529.
  • Blackburn, E. H. (1982). Telomerases. Annu Rev Biochem, 61, 113–119.
  • Hiyama, K., Hirai, Y., Koizumi, S., Akiyama, M., Hiyama, E., Piatyszek, M. A., Shay, J. W., Ishioka, S. and Yamakido, M. (1995). Activation of telomerase in human lymphocytes and hematopoietic progenitor cells. J Immunol, 155, 3711–3715.
  • Adamson, D. J. A., King, D. J. and Haites, N. E. (1992). Significant telomere shortening in childhood leukemia. Cancer Genet Cytogenet, 61, 204–206.
  • Hiyama, E., Hiyama, K., Yokoyama, T., Ichikawa, T. and Matsuura, Y. (1992). Length of telomeric repeats in neuroblastoma: correlation with prognosis and other biological characteristics, Jpn J Cancer Res, 83, 159–164.
  • Hiyama, E., Hiyama, K., Yokoyama, T., Matsuura, Y., Piatyszek, M. A. and Shay, J. W. (1995). Correlating telomerase activity levels with human neuroblastoma outcomes. Nat Med, 1, 249–255.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.