Juvenile exposure to doxorubicin alters the cardiovascular response to adult-onset psychosocial stress in mice

References

• Abdelgawad, I. Y., Grant, M. K. O., Popescu, F. E., Largaespada, D. A., & Zordoky, B. N. (2021). Doxorubicin paradoxically ameliorates tumor-induced inflammation in young mice. International Journal of Molecular Sciences, 22, 9023. https://doi.org/10.3390/ijms22169023
   PubMed Web of Science ®Google Scholar
• Agostinucci, K., Grant, M. K. O., Seelig, D., Yucel, D., van Berlo, J., Bartolomucci, A., Dyck, J. R. B., & Zordoky, B. N. (2022). Divergent cardiac effects of angiotensin II and isoproterenol following juvenile exposure to doxorubicin. Frontiers in Cardiovascular Medicine, 9, 742193. https://doi.org/10.3389/fcvm.2022.742193
   PubMed Web of Science ®Google Scholar
• Agrimi, J., Scalco, A., Agafonova, J., Williams Iii, L., Pansari, N., Keceli, G., Jun, S., Wang, N., Mastorci, F., Tichnell, C., Murray, B., James, C. A., Calkins, H., Zaglia, T., Paolocci, N., & Chelko, S. P. (2020). Psychosocial stress hastens disease progression and sudden death in mice with arrhythmogenic cardiomyopathy. Journal of Clinical Medicine, 9, 3804. https://doi.org/10.3390/jcm9123804
   PubMed Web of Science ®Google Scholar
• Agrimi, J., Spalletti, C., Baroni, C., Keceli, G., Zhu, G., Caragnano, A., Matteucci, M., Chelko, S., Ramirez-Correa, G. A., Bedja, D., Casieri, V., Di Lascio, N., Scalco, A., Beltrami, A. P., Paolocci, N., Caleo, M., & Lionetti, V. (2019). Obese mice exposed to psychosocial stress display cardiac and hippocampal dysfunction associated with local brain-derived neurotrophic factor depletion. EBioMedicine, 47, 384–401. https://doi.org/10.1016/j.ebiom.2019.08.042
   PubMed Web of Science ®Google Scholar
• Ariffin, H., Azanan, M. S., Abd Ghafar, S. S., Oh, L., Lau, K. H., Thirunavakarasu, T., Sedan, A., Ibrahim, K., Chan, A., Chin, T. F., Liew, F. F., Jeyamogan, S., Rosli, E. S., Baharudin, R., Yap, T. Y., Skinner, R., Lum, S. H., & Hainaut, P. (2017). Young adult survivors of childhood acute lymphoblastic leukemia show evidence of chronic inflammation and cellular aging. Cancer, 123(21), 4207–4214. https://doi.org/10.1002/cncr.30857
   PubMed Web of Science ®Google Scholar
• Armstrong, G. T., Oeffinger, K. C., Chen, Y., Kawashima, T., Yasui, Y., Leisenring, W., Stovall, M., Chow, E. J., Sklar, C. A., Mulrooney, D. A., Mertens, A. C., Border, W., Durand, J. B., Robison, L. L., & Meacham, L. R. (2013). Modifiable risk factors and major cardiac events among adult survivors of childhood cancer. Journal of Clinical Oncology, 31(29), 3673–3680. https://doi.org/10.1200/JCO.2013.49.3205
   PubMed Web of Science ®Google Scholar
• Bartolomucci, A., Carola, V., Pascucci, T., Puglisi-Allegra, S., Cabib, S., Lesch, K. P., Parmigiani, S., Palanza, P., & Gross, C. (2010). Increased vulnerability to psychosocial stress in heterozygous serotonin transporter knockout mice. Disease Models & Mechanisms, 3(7–8), 459–470. https://doi.org/10.1242/dmm.004614
   PubMed Web of Science ®Google Scholar
• Bartolomucci, A., Palanza, P., Costoli, T., Savani, E., Laviola, G., Parmigiani, S., & Sgoifo, A. (2003). Chronic psychosocial stress persistently alters autonomic function and physical activity in mice. Physiology & Behavior, 80(1), 57–67. https://doi.org/10.1016/S0031-9384(03)00209-9
   PubMed Web of Science ®Google Scholar
• Bartolomucci, A., Palanza, P., Gaspani, L., Limiroli, E., Panerai, A. E., Ceresini, G., Poli, M. D., & Parmigiani, S. (2001). Social status in mice: Behavioral, endocrine and immune changes are context dependent. Physiology & Behavior, 73(3), 401–410. https://doi.org/10.1016/S0031-9384(01)00453-X
   PubMed Web of Science ®Google Scholar
• Bartolomucci, A., Pederzani, T., Sacerdote, P., Panerai, A. E., Parmigiani, S., & Palanza, P. (2004). Behavioral and physiological characterization of male mice under chronic psychosocial stress. Psychoneuroendocrinology, 29(7), 899–910. https://doi.org/10.1016/j.psyneuen.2003.08.003
   PubMed Web of Science ®Google Scholar
• Blaauwbroek, R., Stant, A. D., Groenier, K. H., Kamps, W. A., Meyboom, B., & Postma, A. (2007). Health-related quality of life and adverse late effects in adult (very) long-term childhood cancer survivors. European Journal of Cancer, 43(1), 122–130. https://doi.org/10.1016/j.ejca.2006.08.003
   PubMed Web of Science ®Google Scholar
• Blaes, A., Konety, S., & Zordoky, B. (2021). Response to schoormans. Journal of the National Cancer Institute, 113(2), 214–215. https://doi.org/10.1093/jnci/djaa158
   PubMedGoogle Scholar
• Bosman, M., Kruger, D. N., Favere, K., Wesley, C. D., Neutel, C. H. G., Van Asbroeck, B., Diebels, O. R., Faes, B., Schenk, T. J., Martinet, W., De Meyer, G. R. Y., Van Craenenbroeck, E. M., & Guns, P. D. F. (2021). Doxorubicin impairs smooth muscle cell contraction: Novel insights in vascular toxicity. International Journal of Molecular Sciences, 22, 12812. https://doi.org/10.3390/ijms222312812
   PubMed Web of Science ®Google Scholar
• Brinkman, T. M., Li, C., Vannatta, K., Marchak, J. G., Lai, J. S., Prasad, P. K., Kimberg, C., Vuotto, S., Di, C., Srivastava, D., Robison, L. L., Armstrong, G. T., & Krull, K. R. (2016). Behavioral, social, and emotional symptom comorbidities and profiles in adolescent survivors of childhood cancer: A report from the childhood cancer survivor study. Journal of Clinical Oncology, 34(28), 3417–3425. https://doi.org/10.1200/JCO.2016.66.4789
   PubMed Web of Science ®Google Scholar
• Carnevali, L., Mastorci, F., Audero, E., Graiani, G., Rossi, S., Macchi, E., Callegari, S., Bartolomucci, A., Nalivaiko, E., Quaini, F., Gross, C., & Sgoifo, A. (2012). Stress-induced susceptibility to sudden cardiac death in mice with altered serotonin homeostasis. PLoS One, 7(7), e41184. https://doi.org/10.1371/journal.pone.0041184
   PubMed Web of Science ®Google Scholar
• Çetin, S., Babaoğlu, K., Başar, E. Z., Deveci, M., & Çorapçıoğlu, F. (2018). Subclinical anthracycline-induced cardiotoxicity in long-term follow-up of asymptomatic childhood cancer survivors: Assessment by speckle tracking echocardiography. Echocardiography, 35(2), 234–240. https://doi.org/10.1111/echo.13743
   PubMed Web of Science ®Google Scholar
• Chen, D. S., Yan, J., & Yang, P. Z. (2022). Cardiomyocyte atrophy, an underestimated contributor in doxorubicin-induced cardiotoxicity. Frontiers in Cardiovascular Medicine, 9, 812578. https://doi.org/10.3389/fcvm.2022.812578
   PubMed Web of Science ®Google Scholar
• Cheung, Y. F., Lam, W. W., Ip, J. J., Cheuk, D. K., Cheng, F. W., Yang, J. Y., Yau, J. P., Ho, K. K., Li, C. K., Li, R. C., Yuen, H. L., Ling, A. S., Li, V. W., & Chan, G. C. (2015). Myocardial iron load and fibrosis in long term survivors of childhood leukemia. Pediatric Blood & Cancer, 62(4), 698–703. https://doi.org/10.1002/pbc.25369
   PubMed Web of Science ®Google Scholar
• Chou, C. H., Hung, C. S., Liao, C. W., Wei, L. H., Chen, C. W., Shun, C. T., Wen, W. F., Wan, C. H., Wu, X. M., Chang, Y. Y., Wu, V. C., Wu, K. D., & Lin, Y. H. (2018). IL-6 trans-signalling contributes to aldosterone-induced cardiac fibrosis. Cardiovascular Research, 114(5), 690–702. https://doi.org/10.1093/cvr/cvy013
   PubMed Web of Science ®Google Scholar
• Costoli, T., Bartolomucci, A., Graiani, G., Stilli, D., Laviola, G., & Sgoifo, A. (2004). Effects of chronic psychosocial stress on cardiac autonomic responsiveness and myocardial structure in mice. American Journal of Physiology Heart and Circulatory Physiology, 286(6), H2133–2140. https://doi.org/10.1152/ajpheart.00869.2003
   PubMed Web of Science ®Google Scholar
• Dadomo, H., Sanghez, V., Di Cristo, L., Lori, A., Ceresini, G., Malinge, I., Parmigiani, S., Palanza, P., Sheardown, M., & Bartolomucci, A. (2011). Vulnerability to chronic subordination stress-induced depression-like disorders in adult 129SvEv male mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 35(6), 1461–1471. https://doi.org/10.1016/j.pnpbp.2010.11.016
   PubMed Web of Science ®Google Scholar
• de Wildt, D. J., de Jong, Y., Hillen, F. C., Steerenberg, P. A., & van Hoesel, Q. G. (1985). Cardiovascular effects of doxorubicin-induced toxicity in the intact Lou/M Wsl rat and in isolated heart preparations. The Journal of Pharmacology and Experimental Therapeutics, 235(1), 234–240.
   PubMed Web of Science ®Google Scholar
• Dutta, S., & Sengupta, P. (2016). Men and mice: Relating their ages. Life Sciences, 152, 244–248. https://doi.org/10.1016/j.lfs.2015.10.025
   PubMed Web of Science ®Google Scholar
• Ehrhardt, M. J., Mulrooney, D. A., Li, C., Baassiri, M. J., Bjornard, K., Sandlund, J. T., Brinkman, T. M., Huang, I. C., Srivastava, D. K., Ness, K. K., Robison, L. L., Hudson, M. M., & Krull, K. R. (2018). Neurocognitive, psychosocial, and quality-of-life outcomes in adult survivors of childhood non-Hodgkin lymphoma. Cancer, 124(2), 417–425. https://doi.org/10.1002/cncr.31019
   PubMed Web of Science ®Google Scholar
• Faber, J., Wingerter, A., Neu, M. A., Henninger, N., Eckerle, S., Munzel, T., Lackner, K. J., Beutel, M. E., Blettner, M., Rathmann, W., Peters, A., Meisinger, C., Linkohr, B., Neuhauser, H., Kaatsch, P., Spix, C., Schneider, A., Merzenich, H., Panova-Noeva, M., Prochaska, J. H., & Wild, P. S. (2018). Burden of cardiovascular risk factors and cardiovascular disease in childhood cancer survivors: Data from the German CVSS-study. European Heart Journal, 39(17), 1555–1562. https://doi.org/10.1093/eurheartj/ehy026
   PubMed Web of Science ®Google Scholar
• Ford, D. E., Mead, L. A., Chang, P. P., Cooper-Patrick, L., Wang, N. Y., & Klag, M. J. (1998). Depression is a risk factor for coronary artery disease in men: The precursors study. Archives of Internal Medicine, 158(13), 1422–1426. https://doi.org/10.1001/archinte.158.13.1422
   PubMedGoogle Scholar
• Germanakis, I., Kalmanti, M., Parthenakis, F., Nikitovic, D., Stiakaki, E., Patrianakos, A., & Vardas, P. E. (2006). Correlation of plasma N-terminal pro-brain natriuretic peptide levels with left ventricle mass in children treated with anthracyclines. International Journal of Cardiology, 108(2), 212–215. https://doi.org/10.1016/j.ijcard.2005.05.006
   PubMed Web of Science ®Google Scholar
• Johannsdottir, I. M. R., Hamre, H., Fossa, S. D., Loge, J. H., Drolsum, L., Lund, M. B., Nordsletten, L., & Kiserud, C. (2017). Adverse health outcomes and associations with self-reported general health in childhood lymphoma survivors. Journal of Adolescent and Young Adult Oncology, 6(3), 470–476. https://doi.org/10.1089/jayao.2017.0018
   PubMed Web of Science ®Google Scholar
• Kamphuis, M. H., Kalmijn, S., Tijhuis, M. A., Geerlings, M. I., Giampaoli, S., Nissinen, A., Grobbee, D. E., & Kromhout, D. (2006). Depressive symptoms as risk factor of cardiovascular mortality in older European men: The Finland, Italy and Netherlands Elderly (FINE) study. European Journal of Cardiovascular Prevention and Rehabilitation, 13(2), 199–206. https://doi.org/10.1097/01.hjr.0000188242.64590.92
   PubMedGoogle Scholar
• Kelly, K. M. (2012). Management of children with high-risk Hodgkin lymphoma. British Journal of Haematology, 157(1), 3–13. https://doi.org/10.1111/j.1365-2141.2011.08975.x
   PubMed Web of Science ®Google Scholar
• Kivimaki, M., Virtanen, M., Elovainio, M., Kouvonen, A., Vaananen, A., & Vahtera, J. (2006). Work stress in the etiology of coronary heart disease–a meta-analysis. Scandinavian Journal of Work, Environment & Health, 32(6), 431–442. https://doi.org/10.5271/sjweh.1049
   PubMed Web of Science ®Google Scholar
• Kuba, K., Esser, P., Mehnert, A., Hinz, A., Johansen, C., Lordick, F., & Gotze, H. (2019). Risk for depression and anxiety in long-term survivors of hematologic cancer. Health Psychology, 38(3), 187–195. https://doi.org/10.1037/hea0000713
   PubMed Web of Science ®Google Scholar
• Leger, K., Slone, T., Lemler, M., Leonard, D., Cochran, C., Bowman, W. P., Bashore, L., & Winick, N. (2015). Subclinical cardiotoxicity in childhood cancer survivors exposed to very low dose anthracycline therapy. Pediatric Blood & Cancer, 62(1), 123–127. https://doi.org/10.1002/pbc.25206
   PubMed Web of Science ®Google Scholar
• Liao, C. W., Chou, C. H., Wu, X. M., Chen, Z. W., Chen, Y. H., Chang, Y. Y., Wu, V. C., Rose-John, S., Hung, C. S., & Lin, Y. H. (2020). Interleukin-6 plays a critical role in aldosterone-induced macrophage recruitment and infiltration in the myocardium. Biochimica et Biophysica Acta Molecular Basis of Disease, 1866(3), 165627. https://doi.org/10.1016/j.bbadis.2019.165627
   PubMed Web of Science ®Google Scholar
• Lipshultz, S. E., Diamond, M. B., Franco, V. I., Aggarwal, S., Leger, K., Santos, M. V., Sallan, S. E., & Chow, E. J. (2014). Managing chemotherapy-related cardiotoxicity in survivors of childhood cancers. Paediatric Drugs, 16(5), 373–389. https://doi.org/10.1007/s40272-014-0085-1
   PubMed Web of Science ®Google Scholar
• Lipshultz, S. E., Lipsitz, S. R., Kutok, J. L., Miller, T. L., Colan, S. D., Neuberg, D. S., Stevenson, K. E., Fleming, M. D., Sallan, S. E., Franco, V. I., Henkel, J. M., Asselin, B. L., Athale, U. H., Clavell, L. A., Michon, B., Laverdiere, C., Larsen, E., Kelly, K. M., & Silverman, L. B. (2013). Impact of hemochromatosis gene mutations on cardiac status in doxorubicin-treated survivors of childhood high-risk leukemia. Cancer, 119(19), 3555–3562. https://doi.org/10.1002/cncr.28256
   PubMed Web of Science ®Google Scholar
• Lipshultz, S. E., Lipsitz, S. R., Sallan, S. E., Simbre, V. C., 2nd, Shaikh, S. L., Mone, S. M., Gelber, R. D., & Colan, S. D. (2002). Long-term enalapril therapy for left ventricular dysfunction in doxorubicin-treated survivors of childhood cancer. Journal of Clinical Oncology, 20(23), 4517–4522. https://doi.org/10.1200/JCO.2002.12.102
   PubMed Web of Science ®Google Scholar
• Lipshultz, S. E., Miller, T. L., Lipsitz, S. R., Neuberg, D. S., Dahlberg, S. E., Colan, S. D., Silverman, L. B., Henkel, J. M., Franco, V. I., Cushman, L. L., Asselin, B. L., Clavell, L. A., Athale, U., Michon, B., Laverdiere, C., Schorin, M. A., Larsen, E., Usmani, N., & Sallan, S. E. (2012). Continuous versus bolus infusion of doxorubicin in children with all: Long-term cardiac outcomes. Pediatrics, 130(6), 1003–1011. https://doi.org/10.1542/peds.2012-0727
   PubMed Web of Science ®Google Scholar
• Lipshultz, S. E., Sambatakos, P., Maguire, M., Karnik, R., Ross, S. W., Franco, V. I., & Miller, T. L. (2014). Cardiotoxicity and cardioprotection in childhood cancer. Acta Haematologica, 132(3–4), 391–399. https://doi.org/10.1159/000360238
   PubMed Web of Science ®Google Scholar
• Maayah, Z. H., Alam, A. S., Takahara, S., Soni, S., Ferdaoussi, M., Matsumura, N., Zordoky, B. N., Eisenstat, D. D., & Dyck, J. R. B. (2021). Resveratrol reduces cardiac NLRP3-inflammasome activation and systemic inflammation to lessen doxorubicin-induced cardiotoxicity in juvenile mice. FEBS Letters, 595(12), 1681–1695. https://doi.org/10.1002/1873-3468.14091
   PubMed Web of Science ®Google Scholar
• Matsumura, N., Zordoky, B. N., Robertson, I. M., Hamza, S. M., Parajuli, N., Soltys, C.-L M., Beker, D. L., Grant, M. K., Razzoli, M., Bartolomucci, A., & Dyck, J. R. B. (2018). Co-administration of resveratrol with doxorubicin in young mice attenuates detrimental late-occurring cardiovascular changes. Cardiovascular Research, 114, 1350–1359. https://doi.org/10.1093/cvr/cvy064
   PubMed Web of Science ®Google Scholar
• Mawad, W., Mertens, L., Pagano, J. J., Riesenkampff, E., Reichert, M. J. E., Mital, S., Kantor, P. F., Greenberg, M., Liu, P., Nathan, P. C., & Grosse-Wortmann, L. (2020). Effect of anthracycline therapy on myocardial function and markers of fibrotic remodelling in childhood cancer survivors. Eur Heart J Cardiovasc Imaging, 22, 435–442. https://doi.org/10.1093/ehjci/jeaa093
   Web of Science ®Google Scholar
• Ness, K. K., Armstrong, G. T., Kundu, M., Wilson, C. L., Tchkonia, T., & Kirkland, J. L. (2015). Frailty in childhood cancer survivors. Cancer, 121(10), 1540–1547. https://doi.org/10.1002/cncr.29211
   PubMed Web of Science ®Google Scholar
• Nysom, K., Holm, K., Lipsitz, S. R., Mone, S. M., Colan, S. D., Orav, E. J., Sallan, S. E., Olsen, J. H., Hertz, H., Jacobsen, J. R., & Lipshultz, S. E. (1998). Relationship between cumulative anthracycline dose and late cardiotoxicity in childhood acute lymphoblastic leukemia. Journal of Clinical Oncology, 16(2), 545–550. https://doi.org/10.1200/JCO.1998.16.2.545
   PubMed Web of Science ®Google Scholar
• Oeffinger, K. C., Mertens, A. C., Sklar, C. A., Kawashima, T., Hudson, M. M., Meadows, A. T., Friedman, D. L., Marina, N., Hobbie, W., Kadan-Lottick, N. S., Schwartz, C. L., Leisenring, W., Robison, L. L., & Childhood Cancer Survivor Study. (2006). Chronic health conditions in adult survivors of childhood cancer. The New England Journal of Medicine, 355(15), 1572–1582. https://doi.org/10.1056/NEJMsa060185
   PubMed Web of Science ®Google Scholar
• Patterson, Z. R., Khazall, R., Mackay, H., Anisman, H., & Abizaid, A. (2013). Central ghrelin signaling mediates the metabolic response of C57BL/6 male mice to chronic social defeat stress. Endocrinology, 154(3), 1080–1091. https://doi.org/10.1210/en.2012-1834
   PubMed Web of Science ®Google Scholar
• Prasad, P. K., Hardy, K. K., Zhang, N., Edelstein, K., Srivastava, D., Zeltzer, L., Stovall, M., Seibel, N. L., Leisenring, W., Armstrong, G. T., Robison, L. L., & Krull, K. (2015). Psychosocial and neurocognitive outcomes in adult survivors of adolescent and early young adult cancer: A report from the childhood cancer survivor study. Journal of Clinical Oncology, 33(23), 2545–2552. https://doi.org/10.1200/JCO.2014.57.7528
   PubMed Web of Science ®Google Scholar
• Rabelo, E., De Angelis, K., Bock, P., Gatelli Fernandes, T., Cervo, F., Bello Klein, A., Clausell, N., & Claudia Irigoyen, M. (2001). Baroreflex sensitivity and oxidative stress in adriamycin-induced heart failure. Hypertension (Dallas, TX: 1979), 38(3 Pt 2), 576–580. https://doi.org/10.1161/hy09t1.096185
   PubMed Web of Science ®Google Scholar
• Razzoli, M., Frontini, A., Gurney, A., Mondini, E., Cubuk, C., Katz, L. S., Cero, C., Bolan, P. J., Dopazo, J., Vidal-Puig, A., Cinti, S., & Bartolomucci, A. (2016). Stress-induced activation of brown adipose tissue prevents obesity in conditions of low adaptive thermogenesis. Molecular Metabolism, 5(1), 19–33. https://doi.org/10.1016/j.molmet.2015.10.005
   PubMed Web of Science ®Google Scholar
• Razzoli, M., Karsten, C., Yoder, J. M., Bartolomucci, A., & Engeland, W. C. (2014). Chronic subordination stress phase advances adrenal and anterior pituitary clock gene rhythms. American Journal of Physiology, Regulatory, Integrative and Comparative Physiology, 307(2), R198–205. https://doi.org/10.1152/ajpregu.00101.2014
   PubMed Web of Science ®Google Scholar
• Razzoli, M., Lindsay, A., Law, M. L., Chamberlain, C. M., Southern, W. M., Berg, M., Osborn, J., Engeland, W. C., Metzger, J. M., Ervasti, J. M., & Bartolomucci, A. (2020). Social stress is lethal in the mdx model of Duchenne muscular dystrophy. EBioMedicine, 55, 102700. https://doi.org/10.1016/j.ebiom.2020.102700
   PubMed Web of Science ®Google Scholar
• Razzoli, M., Sanghez, V., & Bartolomucci, A. (2015). Chronic subordination stress induces hyperphagia and disrupts eating behavior in mice modeling binge-eating-like disorder. Frontiers in Nutrition, 1, 30. https://doi.org/10.3389/fnut.2014.00030
   PubMedGoogle Scholar
• Reagan-Shaw, S., Nihal, M., & Ahmad, N. (2008). Dose translation from animal to human studies revisited. FASEB Journal, 22(3), 659–661. https://doi.org/10.1096/fj.07-9574LSF
   PubMed Web of Science ®Google Scholar
• Rozanski, A., Blumenthal, J. A., & Kaplan, J. (1999). Impact of psychological factors on the pathogenesis of cardiovascular disease and implications for therapy. Circulation, 99(16), 2192–2217. https://doi.org/10.1161/01.cir.99.16.2192
   PubMed Web of Science ®Google Scholar
• Sanghez, V., Cubuk, C., Sebastian-Leon, P., Carobbio, S., Dopazo, J., Vidal-Puig, A., & Bartolomucci, A. (2016). Chronic subordination stress selectively downregulates the insulin signaling pathway in liver and skeletal muscle but not in adipose tissue of male mice. Stress (Amsterdam, Netherlands), 19(2), 214–224. https://doi.org/10.3109/10253890.2016.1151491
   PubMed Web of Science ®Google Scholar
• Sanghez, V., Razzoli, M., Carobbio, S., Campbell, M., McCallum, J., Cero, C., Ceresini, G., Cabassi, A., Govoni, P., Franceschini, P., de Santis, V., Gurney, A., Ninkovic, I., Parmigiani, S., Palanza, P., Vidal-Puig, A., & Bartolomucci, A. (2013). Psychosocial stress induces hyperphagia and exacerbates diet-induced insulin resistance and the manifestations of the metabolic syndrome. Psychoneuroendocrinology, 38(12), 2933–2942. https://doi.org/10.1016/j.psyneuen.2013.07.022
   PubMed Web of Science ®Google Scholar
• Schoormans, D. (2021). RE: Cardiovascular disease in breast cancer survivors: An important topic in breast cancer survivorship. Journal of the National Cancer Institute, 113(2), 212–213. https://doi.org/10.1093/jnci/djaa157
   PubMedGoogle Scholar
• Schoormans, D., Pedersen, S. S., Dalton, S., Rottmann, N., & Poll-Franse, L. V. D. (2016). Cardiovascular co-morbidity in cancer patients: The role of psychological distress. Cardio-Oncology (London, England), 2(1), 9. https://doi.org/10.1186/s40959-016-0019-x
   PubMedGoogle Scholar
• Schoormans, D., van de Poll-Franse, L., Vissers, P., van Herk-Sukel, M. P. P., Pedersen, S. S., Rottmann, N., Horsbol, T., Dalton, S., & Denollet, J. (2017). Pharmaceutically treated anxiety but not depression prior to cancer diagnosis predicts the onset of cardiovascular disease among breast cancer survivors. Breast Cancer Research and Treatment, 166(1), 259–266. https://doi.org/10.1007/s10549-017-4387-1
   PubMed Web of Science ®Google Scholar
• Shen, H., Wang, J., Min, J., Xi, W., Gao, Y., Yin, L., Yu, Y., Liu, K., Xiao, J., Zhang, Y. F., & Wang, Z. N. (2018). Activation of TGF-beta1/alpha-SMA/Col I profibrotic pathway in fibroblasts by galectin-3 contributes to atrial fibrosis in experimental models and patients. Cellular Physiology and Biochemistry: International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 47(2), 851–863. https://doi.org/10.1159/000490077
   PubMedGoogle Scholar
• Simas, B. B., Nunes, E. A., Crestani, C. C., & Speretta, G. F. (2018). Cardiovascular and metabolic consequences of the association between chronic stress and high-fat diet in rats. Stress (Amsterdam, Netherlands), 21(3), 247–256. https://doi.org/10.1080/10253890.2018.1437413
   PubMed Web of Science ®Google Scholar
• Teng, A. E., Noor, B., Ajijola, O. A., & Yang, E. H. (2021). Chemotherapy and radiation-associated cardiac autonomic dysfunction. Current Oncology Reports, 23(2), 14. https://doi.org/10.1007/s11912-020-01013-7
   PubMed Web of Science ®Google Scholar
• Tham, E. B., Haykowsky, M. J., Chow, K., Spavor, M., Kaneko, S., Khoo, N. S., Pagano, J. J., Mackie, A. S., & Thompson, R. B. (2013). Diffuse myocardial fibrosis by T1-mapping in children with subclinical anthracycline cardiotoxicity: Relationship to exercise capacity, cumulative dose and remodeling. Journal of Cardiovascular Magnetic Resonance, 15, 48. https://doi.org/10.1186/1532-429X-15-48
   PubMed Web of Science ®Google Scholar
• Tong, X., Li, V. W., Liu, A. P., So, E. K., Chan, Q., Ho, K. K., Yau, J. P., Cheuk, D. K., Cheung, Y. F., & Ng, M. Y. (2019). Cardiac magnetic resonance T1 mapping in adolescent and young adult survivors of childhood cancers. Circulation: Cardiovascular Imaging, 12, e008453. https://doi.org/10.1161/CIRCIMAGING.118.008453
   PubMed Web of Science ®Google Scholar
• Tremolada, M., Bonichini, S., Basso, G., & Pillon, M. (2016). Post-traumatic stress symptoms and post-traumatic growth in 223 childhood cancer survivors: Predictive risk factors. Frontiers in Psychology, 7, 287. https://doi.org/10.3389/fpsyg.2016.00287
   PubMed Web of Science ®Google Scholar
• van Dalen, E. C., Raphael, M. F., Caron, H. N., & Kremer, L. C. (2011). Treatment including anthracyclines versus treatment not including anthracyclines for childhood cancer. Cochrane Database Systematic Review, 19;(1):CD006647.
   PubMed Web of Science ®Google Scholar
• Vandecruys, E., Mondelaers, V., De Wolf, D., Benoit, Y., & Suys, B. (2012). Late cardiotoxicity after low dose of anthracycline therapy for acute lymphoblastic leukemia in childhood. Journal of Cancer Survivorship, 6(1), 95–101. https://doi.org/10.1007/s11764-011-0186-6
   PubMed Web of Science ®Google Scholar
• Vuotto, S. C., Krull, K. R., Li, C., Oeffinger, K. C., Green, D. M., Patel, S. K., Srivastava, D., Stovall, M., Ness, K. K., Armstrong, G. T., Robison, L. L., & Brinkman, T. M. (2017). Impact of chronic disease on emotional distress in adult survivors of childhood cancer: A report from the Childhood Cancer Survivor Study. Cancer, 123(3), 521–528. https://doi.org/10.1002/cncr.30348
   PubMed Web of Science ®Google Scholar
• Wilcox, R. R. (1987). New statistical procedures for the social sciences: Modern solutions to basic problems. L. Erlbaum Associates.
   Google Scholar
• Yazaki, K., Takahashi, K., Shigemitsu, S., Yamada, M., Iso, T., Kobayashi, M., Akimoto, K., Tamaichi, H., Fujimura, J., Saito, M., Nii, M., & Shimizu, T. (2018). In-depth insight into the mechanisms of cardiac dysfunction in patients with childhood cancer after anthracycline treatment using layer-specific strain analysis. Circulation Journal, 82(3), 715–723. https://doi.org/10.1253/circj.CJ-17-0874
   PubMed Web of Science ®Google Scholar
• Yeh, E. T., & Vejpongsa, P. (2015). Subclinical cardiotoxicity associated with cancer therapy: Early detection and future directions. Journal of the American College of Cardiology, 65(23), 2523–2525. https://doi.org/10.1016/j.jacc.2015.04.012
   PubMed Web of Science ®Google Scholar
• Ylanen, K., Poutanen, T., Savikurki-Heikkila, P., Rinta-Kiikka, I., Eerola, A., & Vettenranta, K. (2013). Cardiac magnetic resonance imaging in the evaluation of the late effects of anthracyclines among long-term survivors of childhood cancer. Journal of the American College of Cardiology, 61(14), 1539–1547. https://doi.org/10.1016/j.jacc.2013.01.019
   PubMed Web of Science ®Google Scholar