- Adams, T.E., Sakurai, H. and Adams, B.M. (1999) "Effect of stress-like concentrations of cortisol on estradiol-dependent expression of gonadotropin-releasing hormone receptor in orchidectomized sheep", Biol. Reprod. 60, 164 - 168
- Arai, K.-I., Lee, F., Miyajima, A., Miyatake, S., Arai, N. and Yokota, T. (1990) "Cytokines: coordinators of immune and inflammatory responses", Annu. Rev. Biochem. 59, 783 - 836
- Battaglia, D.F. (1999). "In search of mechanisms and mediators by which immune stress disrupts reproductive neuroendocrine function and ovarian cyclicity". PhD Thesis, University of Michigan.
- Battaglia, D.F., Bowen, J.M., Krasa, H.B., Thrun, L.A., Viguié, C. and Karsch, F.J. (1997) "Endotoxin inhibits the reproductive neuroendocrine axis while stimulating adrenal steroids: a simultaneous view from hypophyseal portal and peripheral blood", Endocrinology 138, 4273 - 4281
- Battaglia, D.F., Brown, M.E., Krasa, H.B., Thrun, L.A., Viguié, C. and Karsch, F.J. (1998) "Systemic challenge with endotoxin stimulates corticotropin-releasing hormone and arginine vasopressin secretion into hypophyseal portal blood: coincidence with gonadotropin-releasing hormone suppression", Endocrinology 139, 4175 - 4181
- Battaglia, D.F., Beaver, A.B., Harris, T.G., Tanhehco, E., Viguié, C. and Karsch, F.J. (1999) "Endotoxin disrupts the estradiol-induced luteinizing hormone surge: interference with estradiol signal reading, not surge release", Endocrinology 140, 2471 - 2479
- Battaglia, D.F., Krasa, H.B., Padmanabhan, V., Viguié, C. and Karsch, F.J. (2000) "Endocrine alterations that underlie endotoxin-induced disruption of the follicular phase in ewes", Biol. Reprod. 62, 45 - 53
- Blatteis, C.M., Sehic, E. and Li, S. (1998) "Afferent pathways of pyrogen signaling", In: Kluger, M.J., Bartfai, T. and Dinarello, C.A., eds, Molecular Mechanisms of Fever (Ann. N.Y. Acad. Sci., New York) vol. 856, pp 95 - 107
- Bonavera, J.J., Kalra, S.P. and Kalra, P.S. (1993) "Mode of action of interleukin-1 in suppression of pituitary LH release in castrated male rats", Brain Res. 612, 1 - 8
- Bradley, S.G. (1979) "Cellular and molecular mechanisms of action of bacterial endotoxins", Annu. Rev. Microbiol. 33, 67 - 94
- Breen, K., Macfarlane, M., Sakurai, H., Adams, B. and Adams, T. (1999) "Stress-like levels of cortisol increase the negative feedback potency of estradiol in female sheep (abstract)", Biol. Reprod. 60 (suppl. 1), 276
- Briard, N., Barrell, G.K., Billings, H.J., Breen, K.M., Brown, M., Young, E.A. and Karsch, F.J. (2000) "Cortisol does not mediate endotoxin-induced inhibition of pulsatile LH secretion (abstract)", Biol. Reprod. 62 (suppl. 1), 323
- Caraty, A. and Locatelli, A. (1988) "Effect of time after castration on secretion of LHRH and LH in the ram", J. Reprod. Fert. 82, 263 - 269
- Clarke, I.J. and Cummins, J.T. (1982) "The temporal relationship between gonadotropin releasing hormone (GnRH) and luteinizing hormone (LH) secretion in ovariectomized ewes", Endocrinology 111, 1737 - 1739
- Coceani, F. and Akarsu, E.S. (1998) "Prostaglandin E 2 in the pathogenesis of fever: an update", In: Kluger, M.J., Bartfai, T. and Dinarello, C.A., eds, Molecular Mechanisms of Fever (Ann. N.Y. Acad. Sci., New York) vol. 856, pp 76 - 82
- Coceani, F., Bishai, I., Engelberts, D., House, R.V. and Adamson, S.L. (1995) "Response of newborn and adult sheep to pyrogens: relation between fever and brain eicosanoid changes", Brain Res. 700, 191 - 204
- Coleman, E.S., Elassser, T.H., Kemppainen, R.J., Coleman, D.A. and Sartin, J.L. (1993) "Effect of endotoxin on pituitary hormone secretion in sheep", Neuroendocrinology 58, 111 - 122
- Conte-Devolx, B., Guillaume, V., Boudouresque, F., Graziani, N., Magnan, E., Grino, M., Emperaire, N., Nahoul, K., Cataldi, M. and Oliver, C. (1992) "Effects of metyrapone infusion on corticotropin-releasing factor and arginine vasopressin secretion into the hypophysial portal blood of conscious, unrestrained rams", Acta Endocrinol. 127, 435 - 440
- Dadoun, F., Guillaume, V., Sauze, N., Farisse, J., Velut, J.-G., Orsoni, J.-C., Gaillard, R. and Oliver, C. (1998) "Effect of endotoxin on the hypothalamic-pituitary-adrenal axis in sheep", Eur. J. Endocrinol. 138, 193 - 197
- Daley, C.A., Sakurai, H., Adams, B.M. and Adams, T.E. (1999) "Effect of stress-like concentrations of cortisol on gonadotroph function in orchidectomized sheep", Biol. Reprod. 60, 158 - 163
- DeRijk, R., Van Rooijen, N., Tilders, F.J.H., Besedovsky, H.O., Del Rey, A. and Berkenbosch, F. (1991) "Selective depletion of macrophages prevents pituitary-adrenal activation in response to subproigenic, but not pyrogenic, doses of bacterial endotoxin in rats", Endocrinology 129, 330 - 338
- Dobson, H., Essawy, S.A. and Alam, M.G.S. (1988) "Suppression of LH response to gonadotrophin-releasing hormone or oestradiol by ACTH (1-24) treatment in anoestrous ewes", J. Endocrinol. 118, 193 - 197
- Dubey, A.K. and Plant, T.M. (1985) "A suppression of gonadotropin secretion by cortisol in castrated male rhesus monkeys (Macaca mulatta) mediated by the interruption of hypothalamic gonadotropin-releasing hormone release", Biol. Reprod. 33, 423 - 431
- Ebisui, O., Fukata, J., Tominaga, T., Murakami, N., Kobayashi, H., Segawa, H., Muro, S., Naito, Y., Nakai, Y., Masui, Y., Nishida, T. and Imura, H. (1992) "Roles of interleukin-1α and -1β in endotoxin-induced suppression of plasma gonadotropin levels in rats", Endocrinology 130, 3307 - 3313
- Elmquist, J.K., Breder, C.D., Sherin, J.E., Schammell, T.E., Hickey, W.F., Dewitt, D. and Saper, C.B. (1997) "Intravenous lipopolysaccharide induces cyclooxygenase 2-like immunoreactivity in rat brain perivascular microglia and meningeal macrophages", J. Comp. Neurol. 381, 119 - 129
- Feng, Y.-J., Shalts, E., Xia, L., Rivier, J., Rivier, C., Vale, W. and Ferin, M. (1991) "An inhibitory effect of interleukin-1a on basal gonadotropin release in the ovariectomized rhesus monkey: reversal by corticotropin-releasing factor antagonist", Endocrinology 128, 2077 - 2082
- Ferin, M. (1993) "Stress and the gonadal axis in the female rhesus monkey: interface between the immune and neuroendocrine systems", Human Reprod. 8 (suppl. 2), 147 - 150
- Givalois, L., Dornand, J., Mekaouche, M., Solier, M.D., Bristow, A.F., Ixart, G., Siaud, P., Assenmacher, I. and Barbanel, G. (1994) "Temporal cascade of plasma level surges in ACTH, corticosterone, and cytokines in endotoxin-challenged rats", Am. J. Physiol. 267, R164 - R170
- Goodman, R.L. (1994) "Neuroendocrine control of the ovine estrous cycle", In: Knobil, E. and Neill, J.D., eds, The Physiology of Reproduction, 2nd ed. (Raven Press, New York) vol. 2, pp 659 - 709
- Harris, T.G., Battaglia, D.F., Brown, M.E., Brown, M.B., Carlson, N.E., Viguié, C., Williams, C.Y. and Karsch, F.J. (2000) "Prostaglandins mediate the endotoxin-induced suppression of pulsatile gonadotropin-releasing hormone and luteinizing hormone secretion in the ewe", Endocrinology 141, 1050 - 1058
- Kalra, P.S., Sahu, A. and Kalra, S.P. (1990) "Interleukin-1 inhibits the ovarian steroid-induced luteinizing hormone surge and release of hypothalamic luteinizing hormone-releasing hormone in rats", Endocrinology 126, 2145 - 2152
- Kalra, P.S., Edwards, T.G., Xu, B., Jain, M. and Kalra, S.P. (1998) "The anti-gonadotropic effects of cytokines: the role of neuropeptides", Domest. Anim. Endocrinol. 15, 321 - 332
- Karsch, F.J. (1987) "Central actions of ovarian steroids in the feedback regulation of pulsatile secretion of luteinizing hormone", Annu. Rev. Physiol. 49, 365 - 382
- Karsch, F.J., Dahl, G.E., Evans, N.P., Manning, J.M., Mayfield, K.P., Moenter, S.M. and Foster, D.L. (1993) "Seasonal changes in gonadotropin-releasing hormone secretion in the ewe: alteration in response to the negative feedback action of estradiol", Biol. Reprod. 49, 1377 - 1383
- Kluger, M.J. (1991) "Fever: role of pyrogens and cryogens", Physiol. Rev. 71, 93 - 127
- Kujjo, L.L., Bosu, W.T.K. and Perez, G.I. (1995) "Opioid peptides involvement in endotoxin-induced suppression of LH secretion in ovariectomized Holstein heifers", Reprod. Toxicol. 9, 169 - 174
- Kurumbail, R.G., Stevens, A.M., Gierse, J.K., McDonald, J.J., Stegeman, R.A., Pak, J.Y., Gildehaus, D., Miyashiro, J.M., Penning, T.D., Seibert, K., Isakson, P.C. and Stallings, W.C. (1996) "Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents", Nature 384, 644 - 648
- Lohuis, J.A.C.M., Verheijden, J.H.M., Burvenich, C. and van Miert, A.S.J.P.A.M. (1988) "Pathophysiological effects of endotoxins in ruminants", Vet. Quart. 10, 109 - 116
- Macfarlane, M.S., Breen, K.M., Sakurai, H., Adams, B.M. and Adams, T.E. (2000) "Effect of duration of infusion of stress-like concentrations of cortisol on follicular development and the preovulatory surge of LH in sheep", Anim. Reprod. Sci. 63, 167 - 175
- Massart-Leen, A.M., Burvenich, C., Messom, G.V.-V. and Hilderson, H. (1992) "Parital prostaglandin-mediated mechanism controlling the release of cortisol in plasma after intravenous administration of endotoxins", Domest. Anim. Endocrinol. 9, 273 - 283
- Morrison, D.C. and Ryan, J.L. (1987) "Endotoxins and disease mechanisms", Annu. Rev. Med. 38, 417 - 432
- Nappi, R.E. and Rivest, S. (1997) "Effect of immune and metabolic challenges on the luteinizing hormone-releasing hormone neuronal system in cycling female rats: an evaluation at the transcriptional level", Endocrinology 138, 1374 - 1384
- Peter, A.T., Bosu, W.T.K. and DeDecker, R.J. (1989) "Suppression of preovulatory luteinizing hormone surges in heifers after intrauterine infusions of Escherichia coli endotoxin", Am. J. Vet. Res. 50, 368 - 373
- Petraglia, F., Sutton, S., Vale, W. and Plotsky, P. (1987) "Corticotropin-releasing factor decreases plasma luteinizing hormone levels in female rats by inhibiting gonadotropin-releasing hormone release into hypophyseal-portal circulation", Endocrinology 120, 1083 - 1088
- Porter, D.W.F., Lincoln, D.W. and Naylor, A.M. (1990) "Plasma cortisol is increased during the inhibition of LH secretion by central LHRH in the ewe", Neuroendocrinology 51, 705 - 712
- Rivest, S. and Rivier, C. (1993a) "Interleukin-1β inhibits the endogenous expression of the early gene c-fos located within the nucleus of LH-RH neurons and interferes with hypothalamic LH-RH release during proestrus in the rat", Brain Res. 613, 132 - 142
- Rivest, S. and Rivier, C. (1993b) "Centrally injected interleukin-1 beta inhibits the hypothalamic LHRH secretion and circulating LH levels via prostaglandins in rats", J. Neuroendocrinol. 5, 445 - 450
- Rivest, S. and Rivier, C. (1993c) "Central mechanisms and sites of action involved in the inhibitory effects of CRF and cytokines on LHRH neuronal activity", Ann. N.Y. Acad. Sci. 697, 117 - 141
- Rivest, S. and Rivier, C. (1995) "The role of corticotropin-releasing factor and interleukin-1 in the regulation of neurons controlling reproductive functions", Endocr. Rev. 16, 177 - 199
- Rivest, S., Lee, S., Attardi, B. and Rivier, C. (1993) "The chronic intracerebroventricular infusion of interleukin-1β alters the activity of the hypothalamic-pituitary-gonadal axis of cycling rats. I. Effect on LHRH and gonadotropin biosynthesis and secretion", Endocrinology 133, 2424 - 2430
- Rivier, C. (1995) "Influence of immune signals on the hypothalamic-pituitary axis of the rodent", Front. Neuroendocrinol. 16, 151 - 182
- Rivier, C. and Vale, W. (1984) "Influence of corticotropin-releasing factor on reproductive functions in the rat", Endocrinology 114, 914 - 921
- Rivier, C. and Vale, W. (1989) "In the rat, interleukin-1α acts at the level of the brain and the gonads to interfere with gonadotropin and sex steroid secretion", Endocrinology 124, 2105 - 2109
- Sancho-Tello, M., Tash, J.S., Roby, K.F. and Terranova, P.F. (1993) "Effects of lipopolysaccharide on ovarian function in the pregnant mare serum gonadotropin-treated rat", Endocr. J. 1, 503 - 511
- Saper, C. (1998) "Neurobiological basis of fever", In: Kluger, M.J., Bartfai, T. and Dinarello, C.A., eds, Molecular Mechanisms of Fever (Ann. N.Y. Acad. Sci., New York) vol. 856, pp 90 - 94
- Sapolsky, R., Rivier, C., Yamamoto, G., Plotsky, P. and Vale, W. (1987) "Interleukin-1 stimulates the secretion of hypothalamic corticotropin-releasing factor", Science 238, 522 - 524
- Schäfer, M.K.-H., Ulke, C., Thomas, S. and Bette, M. (1998) "Peripheral immune stimulation induces region- and cell-specific changes in cytokine and cytokine receptor gene expression in the pituitary gland (abstract)", Soc. Neurosci. Abstr. 24 (2), 1611
- Shalts, E., Feng, Y.-J. and Ferin, M. (1992) "Vasopressin mediates the interleukin-1α-induced decrease in luteinizing hormone secretion in the ovariectomized rhesus monkey", Endocrinology 131, 153 - 158
- Shalts, E., Xia, L., Xiao, E. and Ferin, M. (1994) "Inhibitory effect of arginine-vasopressin on LH secretion in the ovariectomized rhesus monkey", Neuroendocrinology 59, 336 - 342
- Schobitz, B., De Kloet, E.R. and Holsboer, F. (1994) "Gene expression and function of interleukin 1, interleukin 6 and tumor necrosis factor in the brain", Prog. Neurobiol. 44, 397 - 432
- Takeuchi, Y., Nagabukuro, H., Kizumi, O. and Mori, Y. (1997) "Lipopolysaccharide-induced suppression of hypothalamic gonadotropin-releasing hormone pulse generator in ovariectomized goats", J. Vet. Med. Sci. 59, 93 - 96
- Taylor, C.C. and Terranova, P.F. (1996) "Liopolysaccharide inhibits in vitro luteinizing hormone-stimulated rat ovarian granulosa cell estradiol but not progesterone secretion", Biol. Reprod. 54, 1390 - 1396
- Tilders, F.J.H., DeRijk, R.H., Van Dam, A.M., Vincent, V.A., Schotanus, K. and Persoons, J.H. (1994) "Activation of the hypothalamus-pituitary-adrenal axis by bacterial endotoxins: routes and intermediate signals", Psychoneuroendocrinology 19, 209 - 232
- Ulevitch, R.J. and Tobias, P.S. (1995) "Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin", Annu. Rev. Immunol. 13, 437 - 457
- Van Dam, A.M., Bauer, J., Tilders, F.J.H. and Berkenbosch, R. (1995) "Endotoxin-induced appearance of immunoreactive interleukin-1β in ramified microglia in rat brain: a light and electron microscopic study", Neuroscience 65, 815 - 826
- Williams, C.Y., Harris, T.G., Battaglia, D.F., Viguié, C. and Karsch, F.J. (2001) "Endotoxin inhibits pituitary responsiveness to gonadotropin-releasing hormone", Endocrinology 142, 1915 - 1922
- Xiao, E., Xia-Zhang, L., Barth, A., Zhu, J. and Ferin, M. (1998) "Stress and the menstrual cycle: relevance of cycle quality in the short- and long-term response to a 5-day endotoxin challenge during the follicular phase in the rhesus monkey", J. Clin. Endocrinol. Metab. 83, 2454 - 2460
- Xiao, E., Xia-Zhang, L. and Ferin, M. (1999) "Stress and the menstrual cycle: short- and long- term response to a 5-day endotoxin challenge during the luteal phase in the rhesus monkey", J. Clin. Endocrinol. Metab. 84, 623 - 626
- Xiao, E., Xia-Zhang, L. and Ferin, M. (2000) "Inhibitory effects of endotoxin on LH secretion in the ovariectomized monkey are prevented by naloxone but not by an interleukin-1 receptor antagonist", Neuroimmunomodulation 7, 6 - 15
- Yoo, M.-J., Nishihara, M. and Takahashi, M. (1997a) "Tumor necrosis factor-α mediates endotoxin induced suppression of gonadotropin-releasing hormone pulse generator activity in the rat", Endocr. J. 44, 141 - 148
- Yoo, M.-J., Nishihara, M. and Takahashi, M. (1997b) "Involvement of prostaglandins in suppression of gonadotropin-releasing hormone pulse generator activity by tumor necrosis factor-α", J. Reprod. Dev. 43, 181 - 187
- Yu, W.H., Mastronardi, C.A., Karanth, S. and McCann, S.M. (2001). "Lipopolysaccharide (LPS) stimulates tumor necrosis factor (TNF)-alpha secretion from pituitaries and medial basal hypothalami (MBH) in vitro". Program and Abstracts, 83rd Annual Meeting of the Endocrine Society, 513 (abstract).
Free access
Mechanisms for Ovarian Cycle Disruption by Immune/inflammatory Stress
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.